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PDB: 1 results

4B2D
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BU of 4b2d by Molmil
human PKM2 with L-serine and FBP bound.
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, PYRUVATE KINASE ISOZYMES M1/M2, ...
Authors:Chaneton, B, Hillmann, P, Zheng, L, Martin, A.C.L, Maddocks, O.D.K, Chokkathukalam, A, Coyle, J.E, Jankevics, A, Holding, F.P, Vousden, K.H, Frezza, C, O'Reilly, M, Gottlieb, E.
Deposit date:2012-07-13
Release date:2012-10-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Serine is a natural ligand and allosteric activator of pyruvate kinase M2.
Nature, 491, 2012

227561

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