5WDI
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![BU of 5wdi by Molmil](/molmil-images/mine/5wdi) | Structure of Human Sts-2 histidine phosphatase domain | 分子名称: | SULFATE ION, Ubiquitin-associated and SH3 domain-containing protein A | 著者 | Zhou, W, Yin, Y, Weinheimer, A.W, Kaur, N, Carpino, N, French, J.B. | 登録日 | 2017-07-05 | 公開日 | 2017-08-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Structural and Functional Characterization of the Histidine Phosphatase Domains of Human Sts-1 and Sts-2. Biochemistry, 56, 2017
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5W5G
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![BU of 5w5g by Molmil](/molmil-images/mine/5w5g) | Structure of Human Sts-1 histidine phosphatase domain | 分子名称: | Ubiquitin-associated and SH3 domain-containing protein B | 著者 | Zhou, W, Yin, Y, Weinheimer, A.W, Kaur, N, Carpino, N, French, J.B. | 登録日 | 2017-06-15 | 公開日 | 2017-08-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Structural and Functional Characterization of the Histidine Phosphatase Domains of Human Sts-1 and Sts-2. Biochemistry, 56, 2017
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7UWQ
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![BU of 7uwq by Molmil](/molmil-images/mine/7uwq) | |
6B10
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![BU of 6b10 by Molmil](/molmil-images/mine/6b10) | C. Jejuni Agmatine Deiminase | 分子名称: | PHOSPHATE ION, POTASSIUM ION, Putative peptidyl-arginine deiminase family protein | 著者 | Shek, R, Hicks, K.A, French, J.B. | 登録日 | 2017-09-15 | 公開日 | 2017-12-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structural and Functional Basis for Targeting Campylobacter jejuni Agmatine Deiminase To Overcome Antibiotic Resistance. Biochemistry, 56, 2017
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6B2W
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8U5M
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![BU of 8u5m by Molmil](/molmil-images/mine/8u5m) | Structure of Sts-1 HP domain with rebamipide | 分子名称: | Rebamipide, Ubiquitin-associated and SH3 domain-containing protein B | 著者 | Azia, F, Dey, R, French, J.B. | 登録日 | 2023-09-12 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Rebamipide and Derivatives are Potent, Selective Inhibitors of Histidine Phosphatase Activity of the Suppressor of T Cell Receptor Signaling Proteins. J.Med.Chem., 67, 2024
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8U7E
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![BU of 8u7e by Molmil](/molmil-images/mine/8u7e) | Structure of Sts-1 HP domain with rebamipide derivative | 分子名称: | N-(4-ethylbenzoyl)-3-(2-oxo-1,2-dihydroquinolin-4-yl)-L-alanine, Ubiquitin-associated and SH3 domain-containing protein B | 著者 | Aziz, F, Dey, R, French, J.B. | 登録日 | 2023-09-15 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Rebamipide and Derivatives are Potent, Selective Inhibitors of Histidine Phosphatase Activity of the Suppressor of T Cell Receptor Signaling Proteins. J.Med.Chem., 67, 2024
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6W6Z
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![BU of 6w6z by Molmil](/molmil-images/mine/6w6z) | BlsA ground state | 分子名称: | BLUF domain-containing protein, FLAVIN MONONUCLEOTIDE | 著者 | Chitrakar, I, French, J.B. | 登録日 | 2020-03-18 | 公開日 | 2020-10-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Structural Basis for the Regulation of Biofilm Formation and Iron Uptake in A. baumannii by the Blue-Light-Using Photoreceptor, BlsA. Acs Infect Dis., 6, 2020
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6W72
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![BU of 6w72 by Molmil](/molmil-images/mine/6w72) | BlsA photo-activated state | 分子名称: | BLUF domain-containing protein, FLAVIN MONONUCLEOTIDE | 著者 | Chitrakar, I, French, J.B. | 登録日 | 2020-03-18 | 公開日 | 2020-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Structural Basis for the Regulation of Biofilm Formation and Iron Uptake in A. baumannii by the Blue-Light-Using Photoreceptor, BlsA. Acs Infect Dis., 6, 2020
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4P66
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![BU of 4p66 by Molmil](/molmil-images/mine/4p66) | Electrostatics of Active Site Microenvironments of E. coli DHFR | 分子名称: | CALCIUM ION, Dihydrofolate reductase, METHOTREXATE, ... | 著者 | Liu, C.T, Layfield, J.P, Stewart III, R.J, French, J.B, Hanoian, P, Asbury, J.B, Hammes-Schiffer, S, Benkovic, S.J. | 登録日 | 2014-03-21 | 公開日 | 2014-07-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Probing the electrostatics of active site microenvironments along the catalytic cycle for Escherichia coli dihydrofolate reductase. J.Am.Chem.Soc., 136, 2014
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4P68
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![BU of 4p68 by Molmil](/molmil-images/mine/4p68) | Electrostatics of Active Site Microenvironments for E. coli DHFR | 分子名称: | ACETATE ION, CALCIUM ION, Dihydrofolate reductase, ... | 著者 | Liu, C.T, Layfield, J.P, Stewart III, R.J, French, J.B, Hanoian, P, Asbury, J.B, Hammes-Schiffer, S, Benkovic, S.J. | 登録日 | 2014-03-22 | 公開日 | 2014-07-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Probing the electrostatics of active site microenvironments along the catalytic cycle for Escherichia coli dihydrofolate reductase. J.Am.Chem.Soc., 136, 2014
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6NJ0
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![BU of 6nj0 by Molmil](/molmil-images/mine/6nj0) | Wild-type E. coli MenE with bound m phenylether-linked analogue of OSB-AMS | 分子名称: | 2-succinylbenzoate--CoA ligase, 5'-O-{3-[3-(2-carboxyphenyl)-3-oxopropyl]phenyl}adenosine | 著者 | Si, Y, Yin, Y, French, J.B, Tonge, P.J. | 登録日 | 2019-01-02 | 公開日 | 2019-04-10 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Structure-Based Design, Synthesis, and Biological Evaluation of Non-Acyl Sulfamate Inhibitors of the Adenylate-Forming Enzyme MenE. Biochemistry, 58, 2019
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7LBA
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![BU of 7lba by Molmil](/molmil-images/mine/7lba) | E. coli Agmatinase | 分子名称: | Agmatinase, MANGANESE (II) ION | 著者 | Chitrakar, I, Ahmed, S.F, Torelli, A.T, French, J.B. | 登録日 | 2021-01-07 | 公開日 | 2021-03-31 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the E. coli agmatinase, SPEB. Plos One, 16, 2021
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5C5H
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![BU of 5c5h by Molmil](/molmil-images/mine/5c5h) | R195K E. coli MenE with bound OSB-AMS | 分子名称: | 2-succinylbenzoate--CoA ligase, 5'-O-{[4-(2-carboxyphenyl)-4-oxobutanoyl]sulfamoyl}adenosine, MAGNESIUM ION | 著者 | Matarlo, J.S, Shek, R, Rajashankar, K.R, Tonge, P.J, French, J.B. | 登録日 | 2015-06-19 | 公開日 | 2015-10-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Mechanism of MenE Inhibition by Acyl-Adenylate Analogues and Discovery of Novel Antibacterial Agents. Biochemistry, 54, 2015
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6OH9
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![BU of 6oh9 by Molmil](/molmil-images/mine/6oh9) | Yeast Guanine Deaminase | 分子名称: | NONAETHYLENE GLYCOL, SULFATE ION, Yeast Guanine Deaminase, ... | 著者 | Shek, R.S, French, J.B. | 登録日 | 2019-04-05 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Determinants for Substrate Selectivity in Guanine Deaminase Enzymes of the Amidohydrolase Superfamily. Biochemistry, 58, 2019
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6OHC
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![BU of 6ohc by Molmil](/molmil-images/mine/6ohc) | E. coli Guanine Deaminase | 分子名称: | GLYCEROL, Guanine deaminase, ZINC ION | 著者 | Shek, R.S, French, J.B. | 登録日 | 2019-04-05 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Determinants for Substrate Selectivity in Guanine Deaminase Enzymes of the Amidohydrolase Superfamily. Biochemistry, 58, 2019
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6OHB
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![BU of 6ohb by Molmil](/molmil-images/mine/6ohb) | E. coli Guanine Deaminase | 分子名称: | Guanine deaminase, ZINC ION | 著者 | Shek, R.S, French, J.B. | 登録日 | 2019-04-05 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Determinants for Substrate Selectivity in Guanine Deaminase Enzymes of the Amidohydrolase Superfamily. Biochemistry, 58, 2019
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6OHA
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![BU of 6oha by Molmil](/molmil-images/mine/6oha) | Yeast Guanine Deaminase | 分子名称: | PENTAETHYLENE GLYCOL, Probable guanine deaminase, SULFATE ION, ... | 著者 | Shek, R.S, French, J.B. | 登録日 | 2019-04-05 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structural Determinants for Substrate Selectivity in Guanine Deaminase Enzymes of the Amidohydrolase Superfamily. Biochemistry, 58, 2019
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