4UQX
 
 | | Coevolution of the ATPase ClpV, the TssB-TssC Sheath and the Accessory HsiE Protein Distinguishes Two Type VI Secretion Classes | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, HSIE1 | | 著者 | Forster, A, Planamente, S, Manoli, E, Lossi, N.S, Freemont, P.S, Filloux, A. | | 登録日 | 2014-06-25 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Coevolution of the ATPase Clpv, the Sheath Proteins Tssb and Tssc and the Accessory Protein Tagj/Hsie1 Distinguishes Type Vi Secretion Classes.
J.Biol.Chem., 289, 2014
|
|
4UQW
 | | Coevolution of the ATPase ClpV, the TssB-TssC Sheath and the Accessory HsiE Protein Distinguishes Two Type VI Secretion Classes | | 分子名称: | BENZAMIDINE, PROTEIN CLPV1 | | 著者 | Forster, A, Planamente, S, Manoli, E, Lossi, N.S, Freemont, P.S, Filloux, A. | | 登録日 | 2014-06-25 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Coevolution of the ATPase Clpv, the Sheath Proteins Tssb and Tssc and the Accessory Protein Tagj/Hsie1 Distinguishes Type Vi Secretion Classes.
J.Biol.Chem., 289, 2014
|
|
2BGU
 | | CRYSTAL STRUCTURE OF THE DNA MODIFYING ENZYME BETA-GLUCOSYLTRANSFERASE IN THE PRESENCE AND ABSENCE OF THE SUBSTRATE URIDINE DIPHOSPHOGLUCOSE | | 分子名称: | BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | | 著者 | Vrielink, A, Rueger, W, Driessen, H.P.C, Freemont, P.S. | | 登録日 | 1994-06-09 | | 公開日 | 1995-12-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the DNA modifying enzyme beta-glucosyltransferase in the presence and absence of the substrate uridine diphosphoglucose.
EMBO J., 13, 1994
|
|
5N8N
 | | Contracted sheath of a Pseudomonas aeruginosa type six secretion system consisting of TssB1 and TssC1 | | 分子名称: | EvpB family type VI secretion protein, Type VI secretion protein, family | | 著者 | Salih, O, He, S, Stach, L, Macdonald, J.T, Planamente, S, Manoli, E, Scheres, S, Filloux, A, Freemont, P.S. | | 登録日 | 2017-02-23 | | 公開日 | 2018-01-10 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | Atomic Structure of Type VI Contractile Sheath from Pseudomonas aeruginosa.
Structure, 26, 2018
|
|
2BGT
 | |
6RRT
 | | T=4 MS2 Virus-like-particle | | 分子名称: | Capsid protein | | 著者 | de Martin Garrido, N, Ramlaul, K, Simpson, P.A, Crone, M.A, Freemont, P.S, Aylett, C.H.S. | | 登録日 | 2019-05-20 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (6 Å) | | 主引用文献 | Bacteriophage MS2 displays unreported capsid variability assembling T = 4 and mixed capsids.
Mol.Microbiol., 113, 2020
|
|
6RRS
 | | T=3 MS2 Virus-like particle | | 分子名称: | Capsid protein | | 著者 | de Martin Garrido, N, Ramlaul, K, Simpson, P.A, Crone, M.A, Freemont, P.S, Aylett, C.H.S. | | 登録日 | 2019-05-20 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Bacteriophage MS2 displays unreported capsid variability assembling T = 4 and mixed capsids.
Mol.Microbiol., 113, 2020
|
|
1POS
 | | CRYSTAL STRUCTURE OF A NOVEL DISULFIDE-LINKED "TREFOIL" MOTIF FOUND IN A LARGE FAMILY OF PUTATIVE GROWTH FACTORS | | 分子名称: | PORCINE PANCREATIC SPASMOLYTIC POLYPEPTIDE | | 著者 | De, A, Brown, D, Gorman, M, Carr, M, Sanderson, M.R, Freemont, P.S. | | 登録日 | 1993-10-08 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of a disulfide-linked "trefoil" motif found in a large family of putative growth factors.
Proc.Natl.Acad.Sci.USA, 91, 1994
|
|
3NS9
 | | Crystal structure of CDK2 in complex with inhibitor BS-194 | | 分子名称: | (2S,3S)-3-{[7-(benzylamino)-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-5-yl]amino}butane-1,2,4-triol, Cell division protein kinase 2 | | 著者 | Hazel, P, Freemont, P.S. | | 登録日 | 2010-07-01 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | A Novel Pyrazolo[1,5-a]pyrimidine Is a Potent Inhibitor of Cyclin-Dependent Protein Kinases 1, 2, and 9, Which Demonstrates Antitumor Effects in Human Tumor Xenografts Following Oral Administration.
J.Med.Chem., 53, 2010
|
|
1C3J
 | | T4 PHAGE BETA-GLUCOSYLTRANSFERASE: SUBSTRATE BINDING AND PROPOSED CATALYTIC MECHANISM | | 分子名称: | BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | | 著者 | Morera, S, Imberty, A, Aschke-Sonnenborn, U, Ruger, W, Freemont, P.S. | | 登録日 | 1999-07-28 | | 公開日 | 1999-08-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | T4 phage beta-glucosyltransferase: substrate binding and proposed catalytic mechanism.
J.Mol.Biol., 292, 1999
|
|
6H56
 | |
4UQZ
 | | Coevolution of the ATPase ClpV, the TssB-TssC Sheath and the Accessory HsiE Protein Distinguishes Two Type VI Secretion Classes | | 分子名称: | ACETATE ION, HSIB1, HSIE1 | | 著者 | Forster, A, Planamente, S, Manoli, E, Lossi, N.S, Freemont, P.S, Filloux, A. | | 登録日 | 2014-06-25 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | | 主引用文献 | Coevolution of the ATPase Clpv, the Sheath Proteins Tssb and Tssc and the Accessory Protein Tagj/Hsie1 Distinguishes Type Vi Secretion Classes.
RNA, 20, 2014
|
|
4B5H
 | | Substate bound inactive mutant of Neisseria AP endonuclease in presence of metal ions | | 分子名称: | 5'-D(*CP*GP*AP*TP*GP*GP*GP*TP*AP*GP*CP)-3', 5'-D(*GP*CP*TP*AP*CP*3DRP*CP*AP*TP*CP*GP)-3', MANGANESE (II) ION, ... | | 著者 | Lu, D, Silhan, J, MacDonald, J.T, Carpenter, E.P, Jensen, K, Tang, C.M, Baldwin, G.S, Freemont, P.S. | | 登録日 | 2012-08-03 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
Proc. Natl. Acad. Sci. U.S.A., 109, 2012
|
|
4B5M
 | | Neisseria AP endonuclease bound to the substrate with a cytosine orphan base | | 分子名称: | 5'-D(*3DRP*CP*AP*TP*CP*GP)-3', 5'-D(*CP*GP*AP*TP*GP*CP*GP*TP*AP*GP*CP)-3', 5'-D(*GP*CP*TP*AP*CP)-3', ... | | 著者 | Lu, D, Silhan, J, MacDonald, J.T, Carpenter, E.P, Jensen, K, Tang, C.M, Baldwin, G.S, Freemont, P.S. | | 登録日 | 2012-08-06 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.758 Å) | | 主引用文献 | Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
Proc. Natl. Acad. Sci. U.S.A., 109, 2012
|
|
1BGU
 | | CRYSTAL STRUCTURE OF THE DNA MODIFYING ENZYME BETA-GLUCOSYLTRANSFERASE IN THE PRESENCE AND ABSENCE OF THE SUBSTRATE URIDINE DIPHOSPHOGLUCOSE | | 分子名称: | BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | | 著者 | Vrielink, A, Rueger, W, Driessen, H.P.C, Freemont, P.S. | | 登録日 | 1994-06-09 | | 公開日 | 1994-10-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the DNA modifying enzyme beta-glucosyltransferase in the presence and absence of the substrate uridine diphosphoglucose.
EMBO J., 13, 1994
|
|
1BGT
 | |
1BOR
 | | TRANSCRIPTION FACTOR PML, A PROTO-ONCOPROTEIN, NMR, 1 REPRESENTATIVE STRUCTURE AT PH 7.5, 30 C, IN THE PRESENCE OF ZINC | | 分子名称: | TRANSCRIPTION FACTOR PML, ZINC ION | | 著者 | Borden, K.L.B, Freemont, P.S. | | 登録日 | 1995-09-27 | | 公開日 | 1997-04-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML.
EMBO J., 14, 1995
|
|
1FRE
 | | XNF7 BBOX, DEVELOPMENTAL PROTEIN, PH 7.5, 30 C, WITH ZINC, NMR, 1 STRUCTURE | | 分子名称: | NUCLEAR FACTOR XNF7, ZINC ION | | 著者 | Borden, K.L.B, Freemont, P.S. | | 登録日 | 1996-01-31 | | 公開日 | 1997-02-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Novel topology of a zinc-binding domain from a protein involved in regulating early Xenopus development.
EMBO J., 14, 1995
|
|
4UQY
 | | Coevolution of the ATPase ClpV, the TssB-TssC Sheath and the Accessory HsiE Protein Distinguishes Two Type VI Secretion Classes | | 分子名称: | HSIB1, HSIE1 | | 著者 | Forster, A, Planamente, S, Manoli, E, Lossi, N.S, Freemont, P.S, Filloux, A. | | 登録日 | 2014-06-25 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Coevolution of the ATPase Clpv, the Sheath Proteins Tssb and Tssc and the Accessory Protein Tagj/Hsie1 Distinguishes Type Vi Secretion Classes.
J.Biol.Chem., 289, 2014
|
|
5IIP
 | | Staphylococcus aureus OpuCA | | 分子名称: | Glycine betaine/carnitine/choline ABC transporter%2C ATP-binding protein%2C putative | | 著者 | Tosi, T, Campeotto, I, Freemont, P.S, Grundling, A. | | 登録日 | 2016-03-01 | | 公開日 | 2016-08-24 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The second messenger c-di-AMP inhibits the osmolyte uptake system OpuC in Staphylococcus aureus.
Sci.Signal., 9, 2016
|
|
5JQ5
 | | Crystal structure of CDK2 in complex with inhibitor ICEC0942 | | 分子名称: | (3R,4R)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol, ACETATE ION, Cyclin-dependent kinase 2 | | 著者 | Hazel, P, Freemont, P.S. | | 登録日 | 2016-05-04 | | 公開日 | 2017-02-08 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Inhibitor Selectivity for Cyclin-Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study.
ChemMedChem, 12, 2017
|
|
5JQ8
 | | Crystal structure of CDK2 in complex with inhibitor ICEC0943 | | 分子名称: | (3S,4S)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol, Cyclin-dependent kinase 2 | | 著者 | Hazel, P, Freemont, P.S. | | 登録日 | 2016-05-04 | | 公開日 | 2017-02-08 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Inhibitor Selectivity for Cyclin-Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study.
ChemMedChem, 12, 2017
|
|
6GYW
 | |
6GYY
 | |
6GYX
 | |
