1HS2
 
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5VH8
 | | Structure and dynamics of RNA repeat expansions that cause Huntington's Disease and myotonic dystrophy type 1 | | 分子名称: | RNA (5'-R(*GP*AP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*C)-3') | | 著者 | Chen, J.L, VanEtten, D.M, Fountain, M.A, Yildirim, I, Disney, M.D. | | 登録日 | 2017-04-12 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and Dynamics of RNA Repeat Expansions That Cause Huntington's Disease and Myotonic Dystrophy Type 1.
Biochemistry, 56, 2017
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5VH7
 | | Structure and dynamics of RNA repeat expansions that cause Huntington's Disease and myotonic dystrophy type 1 | | 分子名称: | RNA (5'-R(*GP*AP*CP*CP*AP*GP*CP*AP*G)-3') | | 著者 | Chen, J.L, VanEtten, D.M, Fountain, M.A, Yildirim, I, Disney, M.D. | | 登録日 | 2017-04-12 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and Dynamics of RNA Repeat Expansions That Cause Huntington's Disease and Myotonic Dystrophy Type 1.
Biochemistry, 56, 2017
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9CPG
 | | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1 | | 分子名称: | 4-carbamimidamidophenyl 4-carbamimidamidobenzoate, RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3') | | 著者 | Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L. | | 登録日 | 2024-07-18 | | 公開日 | 2024-08-07 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1.
Bioorg.Med.Chem.Lett., 2024
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9CPJ
 | | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1 | | 分子名称: | RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3') | | 著者 | Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L. | | 登録日 | 2024-07-18 | | 公開日 | 2024-08-07 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1.
Bioorg.Med.Chem.Lett., 2024
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9CPD
 | | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1 | | 分子名称: | 4-[(3-methoxyphenyl)amino]-2-methylquinoline-6-carboximidamide, RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3') | | 著者 | Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L. | | 登録日 | 2024-07-18 | | 公開日 | 2024-08-07 | | 最終更新日 | 2024-08-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structures of small molecules bound to a model of a CUG RNA repeat expansion.
Bioorg.Med.Chem.Lett., 111, 2024
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9CPI
 | | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1 | | 分子名称: | 4-[1-(2-aminoethyl)-4,5-dihydro-1H-imidazol-2-yl]-N-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]benzamide, RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3') | | 著者 | Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L. | | 登録日 | 2024-07-18 | | 公開日 | 2024-08-07 | | 最終更新日 | 2024-08-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structures of small molecules bound to a model of a CUG RNA repeat expansion.
Bioorg.Med.Chem.Lett., 111, 2024
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9DLL
 | | NMR structures of small molecules bound to a model of an RNA CAG repeat expansion. | | 分子名称: | 4-carbamimidamidophenyl 4-carbamimidamidobenzoate, CAG 13-mer RNA (5'-R(*GP*AP*CP*AP*GP*CP*AP*GP*CP*UP*GP*UP*C)-3') | | 著者 | Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L. | | 登録日 | 2024-09-11 | | 公開日 | 2024-09-25 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structures of small molecules bound to a model of an RNA CAG repeat expansion.
Nucleic Acids Res., 2024
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6VA3
 | | Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MQC | | 分子名称: | 4-[(3-methoxyphenyl)amino]-2-methylquinoline-6-carboximidamide, RNA (5'-R(*CP*AP*CP*AP*CP*GP*UP*CP*GP*G)-3'), RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3') | | 著者 | Chen, J.L, Fountain, M.A, Disney, M.D. | | 登録日 | 2019-12-16 | | 公開日 | 2020-05-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing.
J.Am.Chem.Soc., 142, 2020
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6VA2
 | | Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MH5 | | 分子名称: | (2E,2'E)-2,2'-{dibenzo[b,d]thiene-2,8-diyldi[(1E)eth-1-yl-1-ylidene]}bis(N-methylhydrazine-1-carboximidamide), RNA (5'-R(*CP*AP*CP*AP*CP*GP*UP*CP*GP*G)-3'), RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3') | | 著者 | Chen, J.L, Fountain, M.A, Disney, M.D. | | 登録日 | 2019-12-16 | | 公開日 | 2020-05-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing.
J.Am.Chem.Soc., 142, 2020
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6VA1
 | | Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element | | 分子名称: | RNA (5'-R(*CP*AP*CP*AP*CP*GP*UP*CP*GP*G)-3'), RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3') | | 著者 | Chen, J.L, Fountain, M.A, Disney, M.D. | | 登録日 | 2019-12-16 | | 公開日 | 2020-05-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing.
J.Am.Chem.Soc., 142, 2020
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6VA4
 | | Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MIP | | 分子名称: | N-[3-(8-methoxy-4-oxo-4,5-dihydro-3H-pyrimido[5,4-b]indol-3-yl)propyl]-N-methylcyclohexanaminium, RNA (5'-R(*CP*AP*CP*AP*CP*GP*UP*CP*GP*G)-3'), RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3') | | 著者 | Chen, J.L, Fountain, M.A, Disney, M.D. | | 登録日 | 2019-12-16 | | 公開日 | 2020-05-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing.
J.Am.Chem.Soc., 142, 2020
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2L8C
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2L8U
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2L8W
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2LOA
 | | Structural Basis for Bifunctional Zn(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA | | 分子名称: | 4-(1,4,7,10-tetraazacyclododecan-1-ylmethyl)quinoline, DNA (5'-D(*GP*CP*CP*GP*CP*AP*GP*TP*GP*C)-3'), ZINC ION | | 著者 | Morrow, J.R, Fountain, M.A, del Mundo, I.A, Siter, K.E. | | 登録日 | 2012-01-20 | | 公開日 | 2012-03-14 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for Bifunctional Zinc(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA.
Inorg.Chem., 51, 2012
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2LO8
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2LO5
 | | Structural Basis for Bifunctional Zn(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA, Structure of a Thymine bulge | | 分子名称: | DNA (5'-D(*GP*GP*CP*CP*GP*CP*AP*GP*TP*GP*CP*C)-3') | | 著者 | Morrow, J.R, Fountain, M.A, del Mundo, I.A, Siter, K.E. | | 登録日 | 2012-01-17 | | 公開日 | 2012-03-14 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for Bifunctional Zinc(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA.
Inorg.Chem., 51, 2012
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