3EA5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ea5 by Molmil](/molmil-images/mine/3ea5) | Kap95p Binding Induces the Switch Loops of RanGDP to adopt the GTP-bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics | Descriptor: | GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, Importin subunit beta-1, ... | Authors: | Forwood, J.K, Lonhienne, J.K, Guncar, G, Stewart, M, Marfori, M, Kobe, B. | Deposit date: | 2008-08-24 | Release date: | 2008-10-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics. J.Mol.Biol., 383, 2008
|
|
2V1O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2v1o by Molmil](/molmil-images/mine/2v1o) | Crystal structure of N-terminal domain of acyl-CoA thioesterase 7 | Descriptor: | COENZYME A, CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE | Authors: | Forwood, J.K, Thakur, A.S, Guncar, G, Marfori, M, Mouradov, D, Meng, W.N, Robinson, J, Huber, T, Kellie, S, Martin, J.L, Hume, D.A, Kobe, B. | Deposit date: | 2007-05-28 | Release date: | 2007-06-26 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural Basis for Recruitment of Tandem Hotdog Domains in Acyl-Coa Thioesterase 7 and its Role in Inflammation. Proc.Natl.Acad.Sci.USA, 104, 2007
|
|
3ND2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nd2 by Molmil](/molmil-images/mine/3nd2) | Structure of Yeast Importin-beta (Kap95p) | Descriptor: | Importin subunit beta-1 | Authors: | Forwood, J.K, Kobe, B. | Deposit date: | 2010-06-06 | Release date: | 2010-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Quantitative Structural Analysis of Importin-beta Flexibility: Paradigm for Solenoid Protein Structures Structure, 18, 2010
|
|
6RPK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rpk by Molmil](/molmil-images/mine/6rpk) | |
6RPO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rpo by Molmil](/molmil-images/mine/6rpo) | |
6RPL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rpl by Molmil](/molmil-images/mine/6rpl) | |
3SPS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sps by Molmil](/molmil-images/mine/3sps) | |
6UDS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uds by Molmil](/molmil-images/mine/6uds) | |
7JVO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jvo by Molmil](/molmil-images/mine/7jvo) | |
8SUD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sud by Molmil](/molmil-images/mine/8sud) | JC Polyomavirus LTA NLS bound to importin alpha 2 | Descriptor: | Importin subunit alpha-1, Large T antigen | Authors: | Cross, E.M, Forwood, J.K, Alvisi, G. | Deposit date: | 2023-05-12 | Release date: | 2024-02-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals. Protein Sci., 33, 2024
|
|
4ZRB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zrb by Molmil](/molmil-images/mine/4zrb) | |
6WX9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wx9 by Molmil](/molmil-images/mine/6wx9) | SOX2 bound to Importin-alpha 5 | Descriptor: | Importin subunit alpha-5, Transcription factor SOX-2 | Authors: | Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N. | Deposit date: | 2020-05-10 | Release date: | 2020-10-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for nuclear import selectivity of pioneer transcription factor SOX2. Nat Commun, 12, 2021
|
|
6WPR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wpr by Molmil](/molmil-images/mine/6wpr) | |
4ZV3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zv3 by Molmil](/molmil-images/mine/4zv3) | |
8ECH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ech by Molmil](/molmil-images/mine/8ech) | |
7N8J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7n8j by Molmil](/molmil-images/mine/7n8j) | |
7JJM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jjm by Molmil](/molmil-images/mine/7jjm) | Crystal structure of Importin alpha 2 in complex with LSD1 NLS | Descriptor: | CHLORIDE ION, Importin subunit alpha-1, Lysine-specific histone demethylase 1A | Authors: | Tu, W.J, McGuaig, R, Tan, H.Y.A, Hardy, C, Seddiki, N, Ali, S, Dahlstrom, J.E, Bean, E.G, Dunn, J, Forwood, J.K, Tsimbalyuk, S, Smith, K.M, Yip, D, Malik, L, Prasana, T, Milburn, P, Rao, S. | Deposit date: | 2020-07-27 | Release date: | 2020-08-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch. Front Immunol, 11, 2020
|
|
7JJL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jjl by Molmil](/molmil-images/mine/7jjl) | Crystal structure of Importin Alpha 3 in complex with human LSD1 NLS | Descriptor: | Importin subunit alpha-3, Lysine-specific histone demethylase 1A | Authors: | Tu, W.J, McCuaig, R, Tan, H.Y.A, Hardy, K, Seddiki, N, Ali, S, Dahlstrom, J.E, Bean, E.G, Dunn, J, Forwood, J.K, Tsimbalyuk, S, Smith, K, Yip, D, Malik, L, Prasana, T, Milburn, P, Rao, S. | Deposit date: | 2020-07-27 | Release date: | 2020-08-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch. Front Immunol, 11, 2020
|
|
7JK7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jk7 by Molmil](/molmil-images/mine/7jk7) | Crystal structure of Importin alpha 2 in complex with LSD1 NLS S111E mutant | Descriptor: | GLYCEROL, Importin subunit alpha-1, Lysine-specific histone demethylase 1A | Authors: | Tu, W.J, McCuaig, R, Tan, A.H.Y, Hardy, K, Seddiki, N, Ali, S, Dahlstron, J.E, Bean, E.G, Dunn, J, Forwood, J.K, Tsimbalyuk, S, Smith, K.M, Yip, D, Malik, L, Prasana, T, Milburn, P, Rao, S. | Deposit date: | 2020-07-27 | Release date: | 2020-08-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch. Front Immunol, 11, 2020
|
|
8SG7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sg7 by Molmil](/molmil-images/mine/8sg7) | |
2QVT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qvt by Molmil](/molmil-images/mine/2qvt) | Structure of Melampsora lini avirulence protein, AvrL567-D | Descriptor: | AvrL567-D | Authors: | Guncar, G, Wang, C.I, Forwood, J.K, Teh, T, Catanzariti, A.M, Lawrence, G, Schirra, H.J, Anderson, P.A, Ellis, J.G, Dodds, P.N, Kobe, B. | Deposit date: | 2007-08-08 | Release date: | 2007-10-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Crystal structures of flax rust avirulence proteins AvrL567-A and -D reveal details of the structural basis for flax disease resistance specificity. Plant Cell, 19, 2007
|
|
6PZN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pzn by Molmil](/molmil-images/mine/6pzn) | |
6PZM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pzm by Molmil](/molmil-images/mine/6pzm) | |
2Q2B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2q2b by Molmil](/molmil-images/mine/2q2b) | |
2OPC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2opc by Molmil](/molmil-images/mine/2opc) | Structure of Melampsora lini avirulence protein, AvrL567-A | Descriptor: | AvrL567-A, COBALT (II) ION, IMIDAZOLE | Authors: | Guncar, G, Wang, C.I, Forwood, J.K, Teh, T, Catanzariti, A.M, Ellis, J.G, Dodds, P.N, Kobe, B. | Deposit date: | 2007-01-29 | Release date: | 2007-03-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | The use of Co2+ for crystallization and structure determination, using a conventional monochromatic X-ray source, of flax rust avirulence protein. Acta Crystallogr.,Sect.F, 63, 2007
|
|