7FRS
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![BU of 7frs by Molmil](/molmil-images/mine/7frs) | PanDDA analysis group deposition of ground-state model of PTP1B | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 | Authors: | Mehlman, T, Biel, J, Azeem, S.M, Nelson, E.R, Hossain, S, Dunnett, L.E, Paterson, N.G, Douangamath, A, Talon, R, Axford, D, Orins, H, von Delft, F, Keedy, D.A. | Deposit date: | 2022-10-26 | Release date: | 2022-11-23 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B. Elife, 12, 2023
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4BLS
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![BU of 4bls by Molmil](/molmil-images/mine/4bls) | P4 PROTEIN FROM BACTERIOPHAGE PHI12 Q278A MUTANT IN COMPLEX WITH AMPcPP | Descriptor: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, NTPASE P4 | Authors: | El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J. | Deposit date: | 2013-05-04 | Release date: | 2013-08-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution. Nucleic Acids Res., 41, 2013
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4BLR
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![BU of 4blr by Molmil](/molmil-images/mine/4blr) | P4 PROTEIN FROM BACTERIOPHAGE PHI12 IN COMPLEX WITH UTP | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, NTPASE P4, URIDINE 5'-TRIPHOSPHATE | Authors: | El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J. | Deposit date: | 2013-05-04 | Release date: | 2013-08-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution. Nucleic Acids Res., 41, 2013
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2W9N
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![BU of 2w9n by Molmil](/molmil-images/mine/2w9n) | crystal structure of linear di-ubiquitin | Descriptor: | CHLORIDE ION, UBIQUITIN, ZINC ION | Authors: | Komander, D, Reyes-Turcu, F, Wilkinson, K.D, Barford, D. | Deposit date: | 2009-01-27 | Release date: | 2009-04-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Molecular Discrimination of Structurally Equivalent Lys 63-Linked and Linear Polyubiquitin Chains. Embo Rep., 10, 2009
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4BLT
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![BU of 4blt by Molmil](/molmil-images/mine/4blt) | P4 PROTEIN FROM BACTERIOPHAGE PHI12 S292A MUTANT IN COMPLEX WITH AMPcPP | Descriptor: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, NTPASE P4 | Authors: | El Omari, K, Meier, C, Kainov, D, Sutton, G, Grimes, J.M, Poranen, M.M, Bamford, D.H, Tuma, R, Stuart, D.I, Mancini, E.J. | Deposit date: | 2013-05-04 | Release date: | 2013-08-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Tracking in Atomic Detail the Functional Specializations in Viral Reca Helicases that Occur During Evolution. Nucleic Acids Res., 41, 2013
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2IZX
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![BU of 2izx by Molmil](/molmil-images/mine/2izx) | Molecular Basis of AKAP Specificity for PKA Regulatory Subunits | Descriptor: | AKAP-IS, CAMP-DEPENDENT PROTEIN KINASE TYPE II-ALPHA REGULATORY SUBUNIT, DITHIANE DIOL | Authors: | Gold, M.G, Lygren, B, Dokurno, P, Hoshi, N, McConnachie, G, Tasken, K, Carlson, C.R, Scott, J.D, Barford, D. | Deposit date: | 2006-07-27 | Release date: | 2006-11-08 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Molecular Basis of Akap Specificity for Pka Regulatory Subunits. Mol.Cell, 24, 2006
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2J7N
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![BU of 2j7n by Molmil](/molmil-images/mine/2j7n) | Structure of the RNAi polymerase from Neurospora crassa | Descriptor: | GLYCEROL, MAGNESIUM ION, RNA-DEPENDENT RNA POLYMERASE | Authors: | Salgado, P.S, Koivunen, M.R.L, Makeyev, E.V, Bamford, D.H, Stuart, D.I, Grimes, J.M. | Deposit date: | 2006-10-13 | Release date: | 2006-12-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Structure of an Rnai Polymerase Links RNA Silencing and Transcription. Plos Biol., 4, 2006
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2YIB
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![BU of 2yib by Molmil](/molmil-images/mine/2yib) | Structure of the RNA polymerase VP1 from Infectious Pancreatic Necrosis Virus | Descriptor: | RNA-DIRECTED RNA POLYMERASE | Authors: | Graham, S.C, Sarin, L.P, Bahar, M.W, Myers, R.A, Stuart, D.I, Bamford, D.H, Grimes, J.M. | Deposit date: | 2011-05-11 | Release date: | 2011-07-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | The N-Terminus of the RNA Polymerase from Infectious Pancreatic Necrosis Virus is the Determinant of Genome Attachment. Plos Pathog., 7, 2011
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2Y4I
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![BU of 2y4i by Molmil](/molmil-images/mine/2y4i) | KSR2-MEK1 heterodimer | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1, ... | Authors: | Brennan, D.F, Barford, D. | Deposit date: | 2011-01-06 | Release date: | 2011-01-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.46 Å) | Cite: | A Raf-Induced Allosteric Transition of Ksr Stimulates Ksr and Raf Phosphorylation of Mek Nature, 472, 2011
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4B02
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![BU of 4b02 by Molmil](/molmil-images/mine/4b02) | The C-terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage phi6 RNA-Dependent RNA Polymerase | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | Authors: | Sarin, L.P, Wright, S, Chen, Q, Degerth, L.H, Stuart, D.I, Grimes, J.M, Bamford, D.H, Poranen, M.M. | Deposit date: | 2012-06-27 | Release date: | 2012-08-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The C-Terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage Phi6 RNA-Dependent RNA Polymerase. Virology, 432, 2012
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4A8O
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![BU of 4a8o by Molmil](/molmil-images/mine/4a8o) | Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation | Descriptor: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | Authors: | Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M. | Deposit date: | 2011-11-21 | Release date: | 2012-07-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation. J.Virol., 86, 2012
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2JF5
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![BU of 2jf5 by Molmil](/molmil-images/mine/2jf5) | crystal structure of Lys63-linked di-ubiquitin | Descriptor: | CADMIUM ION, CHLORIDE ION, COBALT (II) ION, ... | Authors: | Komander, D, Odenwaelder, P, Barford, D. | Deposit date: | 2007-01-26 | Release date: | 2008-02-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Molecular Discrimination of Structurally Equivalent Lys 63-Linked and Linear Polyubiquitin Chains. Embo Rep., 10, 2009
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2VHC
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![BU of 2vhc by Molmil](/molmil-images/mine/2vhc) | P4 PROTEIN FROM BACTERIOPHAGE PHI12 N234G mutant in complex with AMPCPP and MN | Descriptor: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MANGANESE (II) ION, NTPASE P4 | Authors: | Kainov, D.E, Mancini, E.J, Telenius, J, Lisal, J, Grimes, J.M, Bamford, D.H, Stuart, D.I, Tuma, R. | Deposit date: | 2007-11-20 | Release date: | 2007-12-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural Basis of Mechanochemical Coupling in a Hexameric Molecular Motor. J.Biol.Chem., 283, 2008
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1W9H
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![BU of 1w9h by Molmil](/molmil-images/mine/1w9h) | The Structure of a Piwi protein from Archaeoglobus fulgidus. | Descriptor: | CADMIUM ION, CHLORIDE ION, HYPOTHETICAL PROTEIN AF1318, ... | Authors: | Parker, J.S, Roe, S.M, Barford, D. | Deposit date: | 2004-10-13 | Release date: | 2005-01-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure of a Piwi Protein Suggests Mechanisms for Sirna Recognition and Slicer Activity Embo J., 23, 2004
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2VHJ
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![BU of 2vhj by Molmil](/molmil-images/mine/2vhj) | P4 PROTEIN FROM BACTERIOPHAGE PHI12 S252A mutant in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, NTPASE P4 | Authors: | Kainov, D.E, Mancini, E.J, Telenius, J, Lisal, J, Grimes, J.M, Bamford, D.H, Stuart, D.I, Tuma, R. | Deposit date: | 2007-11-21 | Release date: | 2007-12-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Basis of Mechanochemical Coupling in a Hexameric Molecular Motor. J.Biol.Chem., 283, 2008
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2V0P
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![BU of 2v0p by Molmil](/molmil-images/mine/2v0p) | The Structure of Tap42 Alpha4 Subunit | Descriptor: | TYPE 2A PHOSPHATASE-ASSOCIATED PROTEIN 42, ZINC ION | Authors: | Roe, S.M, Yang, J, Barford, D. | Deposit date: | 2007-05-15 | Release date: | 2007-07-17 | Last modified: | 2019-05-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Structure of Tap42/Alpha4 Reveals a Tetratricopeptide Repeat-Like Fold and Provides Insights Into Pp2A Regulation. Biochemistry, 46, 2007
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2VHQ
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![BU of 2vhq by Molmil](/molmil-images/mine/2vhq) | P4 PROTEIN FROM BACTERIOPHAGE PHI12 S252A mutant in complex with ATP AND MG | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, NTPASE P4 | Authors: | Kainov, D.E, Mancini, E.J, Telenius, J, Lisal, J, Grimes, J.M, Bamford, D.H, Stuart, D.I, Tuma, R. | Deposit date: | 2007-11-22 | Release date: | 2007-12-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural Basis of Mechanochemical Coupling in a Hexameric Molecular Motor. J.Biol.Chem., 283, 2008
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2V55
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![BU of 2v55 by Molmil](/molmil-images/mine/2v55) | Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Komander, D, Garg, R, Wan, P.T.C, Ridley, A.J, Barford, D. | Deposit date: | 2008-10-01 | Release date: | 2008-11-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.705 Å) | Cite: | Mechanism of Multi-Site Phosphorylation from a Rock-I:Rhoe Complex Structure. Embo J., 27, 2008
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2VHT
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![BU of 2vht by Molmil](/molmil-images/mine/2vht) | P4 PROTEIN FROM BACTERIOPHAGE PHI12 R279A mutant in complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, NTPASE P4 | Authors: | Kainov, D.E, Mancini, E.J, Telenius, J, Lisal, J, Grimes, J.M, Bamford, D.H, Stuart, D.I, Tuma, R. | Deposit date: | 2007-11-25 | Release date: | 2007-12-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis of Mechanochemical Coupling in a Hexameric Molecular Motor. J.Biol.Chem., 283, 2008
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2VFK
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![BU of 2vfk by Molmil](/molmil-images/mine/2vfk) | AKAP18 delta central domain - AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, AKAP18 DELTA | Authors: | Gold, M.G, Smith, F.D, Scott, J.D, Barford, D. | Deposit date: | 2007-11-05 | Release date: | 2008-05-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Akap18 Contains a Phosphoesterase Domain that Binds AMP J.Mol.Biol., 375, 2008
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2YIA
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![BU of 2yia by Molmil](/molmil-images/mine/2yia) | Structure of the RNA polymerase VP1 from Infectious Pancreatic Necrosis Virus | Descriptor: | POTASSIUM ION, RNA-DIRECTED RNA POLYMERASE | Authors: | Graham, S.C, Sarin, L.P, Bahar, M.W, Myers, R.A, Stuart, D.I, Bamford, D.H, Grimes, J.M. | Deposit date: | 2011-05-11 | Release date: | 2011-07-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | The N-Terminus of the RNA Polymerase from Infectious Pancreatic Necrosis Virus is the Determinant of Genome Attachment. Plos Pathog., 7, 2011
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2VHU
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![BU of 2vhu by Molmil](/molmil-images/mine/2vhu) | P4 PROTEIN FROM BACTERIOPHAGE PHI12 K241C mutant in complex with ADP and MgCl | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NTPASE P4 | Authors: | Kainov, D.E, Mancini, E.J, Telenius, J, Lisal, J, Grimes, J.M, Bamford, D.H, Stuart, D.I, Tuma, R. | Deposit date: | 2007-11-25 | Release date: | 2007-12-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural Basis of Mechanochemical Coupling in a Hexameric Molecular Motor. J.Biol.Chem., 283, 2008
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2YI8
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![BU of 2yi8 by Molmil](/molmil-images/mine/2yi8) | Structure of the RNA polymerase VP1 from Infectious Pancreatic Necrosis Virus | Descriptor: | CHLORIDE ION, POTASSIUM ION, RNA-DIRECTED RNA POLYMERASE | Authors: | Graham, S.C, Sarin, L.P, Bahar, M.W, Myers, R.A, Stuart, D.I, Bamford, D.H, Grimes, J.M. | Deposit date: | 2011-05-11 | Release date: | 2011-07-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The N-Terminus of the RNA Polymerase from Infectious Pancreatic Necrosis Virus is the Determinant of Genome Attachment. Plos Pathog., 7, 2011
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2VFL
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![BU of 2vfl by Molmil](/molmil-images/mine/2vfl) | AKAP18 delta central domain - CMP | Descriptor: | AKAP18 DELTA, CYTIDINE-5'-MONOPHOSPHATE | Authors: | Gold, M.G, Smith, F.D, Scott, J.D, Barford, D. | Deposit date: | 2007-11-05 | Release date: | 2008-05-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Akap18 Contains a Phosphoesterase Domain that Binds AMP J.Mol.Biol., 375, 2008
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3ZN3
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![BU of 3zn3 by Molmil](/molmil-images/mine/3zn3) | N-terminal domain of S. pombe Cdc23 APC subunit | Descriptor: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 8, MERCURY (II) ION | Authors: | Zhang, Z, Yang, J, Conin, N, Kulkarni, K, Barford, D. | Deposit date: | 2013-02-13 | Release date: | 2013-02-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Four Canonical Tpr Subunits of Human Apc/C Form Related Homo-Dimeric Structures and Stack in Parallel to Form a Tpr Suprahelix J.Mol.Biol., 425, 2013
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