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PDB: 94 results

1SLV
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RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; COPPER-BOUND
Descriptor: ACETATE ION, ANIONIC TRYPSIN, CALCIUM ION, ...
Authors:Brinen, L.S, Fletterick, R.J.
Deposit date:1996-02-07
Release date:1996-07-11
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray structures of a designed binding site in trypsin show metal-dependent geometry.
Biochemistry, 35, 1996
1TRM
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BU of 1trm by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF ASN102 MUTANT OF TRYPSIN. ROLE OF ASP102 IN SERINE PROTEASE CATALYSIS
Descriptor: BENZAMIDINE, CALCIUM ION, TRYPSIN
Authors:Sprang, S, Standing, T, Fletterick, R.J.
Deposit date:1987-10-21
Release date:1988-07-16
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis.
Science, 237, 1987
1SLX
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RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; ZINC-BOUND
Descriptor: ACETATE ION, ANIONIC TRYPSIN, CALCIUM ION, ...
Authors:Brinen, L.S, Fletterick, R.J.
Deposit date:1996-02-07
Release date:1996-07-11
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray structures of a designed binding site in trypsin show metal-dependent geometry.
Biochemistry, 35, 1996
1TC1
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A 1.4 ANGSTROM CRYSTAL STRUCTURE FOR THE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE OF TRYPANOSOMA CRUZI
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FORMYCIN B, PROTEIN (HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE)
Authors:Focia, P.J, Craig III, S.P, Nieves-Alicea, R, Fletterick, R.J, Eakin, A.E.
Deposit date:1998-09-30
Release date:1999-10-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:A 1.4 A crystal structure for the hypoxanthine phosphoribosyltransferase of Trypanosoma cruzi.
Biochemistry, 37, 1998
1EAP
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CRYSTAL STRUCTURE OF A CATALYTIC ANTIBODY WITH A SERINE PROTEASE ACTIVE SITE
Descriptor: IGG2B-KAPPA 17E8 FAB (HEAVY CHAIN), IGG2B-KAPPA 17E8 FAB (LIGHT CHAIN), PHENYL[1-(N-SUCCINYLAMINO)PENTYL]PHOSPHONATE
Authors:Zhou, G.W, Guo, J, Huang, W, Scanlan, T.S, Fletterick, R.J.
Deposit date:1994-08-10
Release date:1994-12-20
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a catalytic antibody with a serine protease active site.
Science, 265, 1994
1EZU
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ECOTIN Y69F, D70P BOUND TO D102N TRYPSIN
Descriptor: CALCIUM ION, ECOTIN, TRYPSIN II, ...
Authors:Gillmor, S.A, Takeuchi, T, Yang, S.Q, Craik, C.S, Fletterick, R.J.
Deposit date:2000-05-11
Release date:2000-06-23
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Compromise and accommodation in ecotin, a dimeric macromolecular inhibitor of serine proteases.
J.Mol.Biol., 299, 2000
1EZS
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CRYSTAL STRUCTURE OF ECOTIN MUTANT M84R, W67A, G68A, Y69A, D70A BOUND TO RAT ANIONIC TRYPSIN II
Descriptor: CALCIUM ION, ECOTIN, TRYPSIN II, ...
Authors:Gillmor, S.A, Takeuchi, T, Yang, S.Q, Craik, C.S, Fletterick, R.J.
Deposit date:2000-05-11
Release date:2000-06-23
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Compromise and accommodation in ecotin, a dimeric macromolecular inhibitor of serine proteases.
J.Mol.Biol., 299, 2000
1P0S
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Crystal Structure of Blood Coagulation Factor Xa in Complex with Ecotin M84R
Descriptor: Coagulation factor X precursor, Ecotin precursor, MAGNESIUM ION, ...
Authors:Wang, S.X, Hur, E, Sousa, C.A, Brinen, L, Slivka, E.J, Fletterick, R.J.
Deposit date:2003-04-10
Release date:2003-08-26
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Extended Interactions and Gla Domain of Blood Coagulation Factor Xa
Biochemistry, 42, 2003
1SDM
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Crystal structure of kinesin-like calmodulin binding protein
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, kinesin heavy chain-like protein
Authors:Vinogradova, M.V, Reddy, V.S, Reddy, A.S, Sablin, E.P, Fletterick, R.J.
Deposit date:2004-02-13
Release date:2004-06-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of kinesin regulated by Ca(2+)-calmodulin.
J.Biol.Chem., 279, 2004
1Q4X
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Crystal Structure of Human Thyroid Hormone Receptor beta LBD in complex with specific agonist GC-24
Descriptor: Thyroid hormone receptor beta-1, [4-(3-BENZYL-4-HYDROXYBENZYL)-3,5-DIMETHYLPHENOXY]ACETIC ACID
Authors:Borngraeber, S, Budny, M.J, Chiellini, G, Cunha-Lima, S.T, Togashi, M, Webb, P, Baxter, J.D, Scanlan, T.S, Fletterick, R.J.
Deposit date:2003-08-04
Release date:2004-02-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor.
Proc.Natl.Acad.Sci.USA, 100, 2003
1T79
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Crystal structure of the androgen receptor ligand binding domain in complex with a FxxLW motif
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, FxxLW motif peptide
Authors:Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
Deposit date:2004-05-08
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
1PK5
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BU of 1pk5 by Molmil
Crystal structure of the orphan nuclear receptor LRH-1
Descriptor: Orphan nuclear receptor NR5A2
Authors:Sablin, E.P, Krylova, I.N, Fletterick, R.J, Ingraham, H.A.
Deposit date:2003-06-04
Release date:2003-07-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for ligand-independent activation of the orphan nuclear receptor LRH-1
Mol.Cell, 11, 2003
1T74
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Crystal structure of the androgen receptor ligand binding domain in complex with a WxxLF motif
Descriptor: 1,2-ETHANEDIOL, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, ...
Authors:Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
Deposit date:2004-05-07
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
1T7F
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Crystal structure of the androgen receptor ligand binding domain in complex with a LxxLL motif
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, LxxLL motif peptide
Authors:Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
Deposit date:2004-05-10
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
1T7M
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Crystal structure of the androgen receptor ligand binding domain in complex with a FxxYF motif
Descriptor: 1,2-ETHANEDIOL, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, ...
Authors:Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
Deposit date:2004-05-10
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
1T7T
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Crystal structure of the androgen receptor ligand binding domain in complex with 5-alpha dihydrotestosterone
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor
Authors:Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
Deposit date:2004-05-10
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
1T76
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Crystal structure of the androgen receptor ligand binding domain in complex with a WxxVW motif
Descriptor: 1,2-ETHANEDIOL, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, ...
Authors:Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
Deposit date:2004-05-08
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
1T7R
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BU of 1t7r by Molmil
Crystal structure of the androgen receptor ligand binding domain in complex with a FxxLF motif
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, FxxLF motif peptide
Authors:Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
Deposit date:2004-05-10
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
1T73
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Crystal structure of the androgen receptor ligand binding domain in complex with a FxxFF motif
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, FxxFF motif peptide, ...
Authors:Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J.
Deposit date:2004-05-07
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
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數據於2024-08-28公開中

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