4P6T
 
 | | Crystal Structure of tyrosinase from Bacillus megaterium with p-tyrosol in the active site | | 分子名称: | 4-(2-hydroxyethyl)phenol, COPPER (II) ION, Tyrosinase | | 著者 | Goldfeder, M, Kanteev, M, Adir, N, Fishman, A. | | 登録日 | 2014-03-25 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Determination of tyrosinase substrate-binding modes reveals mechanistic differences between type-3 copper proteins.
Nat Commun, 5, 2014
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6QXD
 | | Crystal Structure of tyrosinase from Bacillus megaterium with JKB inhibitor in the active site. | | 分子名称: | (2,4-dinitrophenyl)-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]methanone, COPPER (II) ION, Tyrosinase | | 著者 | Deri Zenaty, B, Gitto, R, Pazy, Y, Fishman, A. | | 登録日 | 2019-03-07 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.317 Å) | | 主引用文献 | Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile.
Eur.J.Med.Chem., 178, 2019
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5BRT
 | | Crystal Structure of 2-hydroxybiphenyl 3-monooxygenase from Pseudomonas azelaica with 2-hydroxybiphenyl in the active site | | 分子名称: | 2-HYDROXYBIPHENYL, 2-hydroxybiphenyl-3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Kanteev, M, Bregman-Cohen, A, Deri, B, Adir, N, Fishman, A. | | 登録日 | 2015-06-01 | | 公開日 | 2015-08-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A crystal structure of 2-hydroxybiphenyl 3-monooxygenase with bound substrate provides insights into the enzymatic mechanism.
Biochim.Biophys.Acta, 1854, 2015
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7Z5P
 | | Bilirubin oxidase from Bacillus pumilus | | 分子名称: | COPPER (II) ION, Copper oxidase | | 著者 | Gihaz, S, Herzallh, N.S, Cohen, Y, Bachar, O, Fishman, A, Yehezkeli, O. | | 登録日 | 2022-03-09 | | 公開日 | 2022-05-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.991 Å) | | 主引用文献 | The Structure of Bilirubin Oxidase from Bacillus pumilus Reveals a Unique Disulfide Bond for Site-Specific Direct Electron Transfer.
Biosensors (Basel), 12, 2022
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5I3A
 | | Crystal Structure of tyrosinase from Bacillus megaterium with configuration A of hydroquinone inhibitor in the active site | | 分子名称: | Tyrosinase, ZINC ION, benzene-1,4-diol | | 著者 | Kanteev, M, Deri, B, Adir, N, Fishman, A. | | 登録日 | 2016-02-10 | | 公開日 | 2016-10-12 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The unravelling of the complex pattern of tyrosinase inhibition.
Sci Rep, 6, 2016
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5I3B
 | | Crystal Structure of tyrosinase from Bacillus megaterium with configuration B of hydroquinone inhibitor in the active site | | 分子名称: | Tyrosinase, ZINC ION, benzene-1,4-diol | | 著者 | Kanteev, M, Deri, B, Adir, N, Fishman, A. | | 登録日 | 2016-02-10 | | 公開日 | 2016-10-12 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The unravelling of the complex pattern of tyrosinase inhibition.
Sci Rep, 6, 2016
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5I38
 | | Crystal Structure of tyrosinase from Bacillus megaterium with inhibitor kojic acid in the active site | | 分子名称: | 5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE, COPPER (II) ION, Tyrosinase | | 著者 | Kanteev, M, Goldfeder, M, Deri, B, Adir, N, Fishman, A. | | 登録日 | 2016-02-10 | | 公開日 | 2016-10-12 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The unravelling of the complex pattern of tyrosinase inhibition.
Sci Rep, 6, 2016
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4D87
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5OAE
 | | Crystal Structure of tyrosinase from Bacillus megaterium with SVF inhibitor in the active site | | 分子名称: | 1-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]ethanone, COPPER (II) ION, Tyrosinase | | 著者 | Deri, B, Gitto, R, Pazy Benhar, Y, Fishman, A. | | 登録日 | 2017-06-21 | | 公開日 | 2018-04-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments.
J. Med. Chem., 61, 2018
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6S3J
 | | Crystal Structure of lipase from Geobacillus stearothermophilus T6 variant E134C/F149C | | 分子名称: | CALCIUM ION, Lipase, ZINC ION | | 著者 | Gihaz, S, Bash, Y, Rush, I, Shahar, A, Pazy, Y, Fishman, A. | | 登録日 | 2019-06-25 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Bridges to Stability: Engineering Disulfide Bonds Towards Enhanced Lipase Biodiesel Synthesis
Chemcatchem, 2019
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6S3V
 | | Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant E251C/G332C | | 分子名称: | CALCIUM ION, Lipase, ZINC ION | | 著者 | Gihaz, S, Bash, Y, Rush, I, Shahar, A, Pazy, Y, Fishman, A. | | 登録日 | 2019-06-26 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Bridges to Stability: Engineering Disulfide Bonds Towards Enhanced Lipase Biodiesel Synthesis
Chemcatchem, 2019
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6S3G
 | | Crystal Structure of lipase from Geobacillus stearothermophilus T6 variant A187C/F291C | | 分子名称: | CALCIUM ION, Lipase, ZINC ION | | 著者 | Gihaz, S, Bash, Y, Rush, I, Shahar, A, Pazy, Y, Fishman, A. | | 登録日 | 2019-06-25 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Bridges to Stability: Engineering Disulfide Bonds Towards Enhanced Lipase Biodiesel Synthesis
Chemcatchem, 2019
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4P6S
 | | Crystal Structure of tyrosinase from Bacillus megaterium with L-DOPA in the active site | | 分子名称: | 3,4-DIHYDROXYPHENYLALANINE, Tyrosinase, ZINC ION | | 著者 | Goldfeder, M, Kanteev, M, Adir, N, Fishman, A. | | 登録日 | 2014-03-25 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Determination of tyrosinase substrate-binding modes reveals mechanistic differences between type-3 copper proteins.
Nat Commun, 5, 2014
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4P6R
 | | Crystal Structure of tyrosinase from Bacillus megaterium with tyrosine in the active site | | 分子名称: | TYROSINE, Tyrosinase, ZINC ION | | 著者 | Goldfeder, M, Kanteev, M, Adir, N, Fishman, A. | | 登録日 | 2014-03-25 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Determination of tyrosinase substrate-binding modes reveals mechanistic differences between type-3 copper proteins.
Nat Commun, 5, 2014
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4X71
 | | Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant A269T | | 分子名称: | CALCIUM ION, Lipase, ZINC ION | | 著者 | Kanteev, M, Dror, A, Gihaz, S, Shahar, A, Fishman, A. | | 登録日 | 2014-12-09 | | 公開日 | 2015-06-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural insights into methanol-stable variants of lipase T6 from Geobacillus stearothermophilus.
Appl.Microbiol.Biotechnol., 99, 2015
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4Z2U
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4X7B
 | | Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant H86Y/A269T | | 分子名称: | CALCIUM ION, Lipase, ZINC ION | | 著者 | Kanteev, M, Dror, A, Gihaz, S, Fishman, A. | | 登録日 | 2014-12-09 | | 公開日 | 2015-06-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insights into methanol-stable variants of lipase T6 from Geobacillus stearothermophilus.
Appl.Microbiol.Biotechnol., 99, 2015
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4X6U
 | | Crystal Structure of lipase from Geobacillus stearothermophilus T6 | | 分子名称: | CALCIUM ION, Lipase, ZINC ION | | 著者 | Kanteev, M, Dror, A, Gihaz, S, Fishman, A. | | 登録日 | 2014-12-09 | | 公開日 | 2015-06-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Structural insights into methanol-stable variants of lipase T6 from Geobacillus stearothermophilus.
Appl.Microbiol.Biotechnol., 99, 2015
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4X85
 | | Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant H86Y/A269T/R374W | | 分子名称: | CALCIUM ION, Lipase, ZINC ION | | 著者 | Kanteev, M, Dror, A, Gihaz, S, Fishman, A. | | 登録日 | 2014-12-10 | | 公開日 | 2015-06-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.192 Å) | | 主引用文献 | Structural insights into methanol-stable variants of lipase T6 from Geobacillus stearothermophilus.
Appl.Microbiol.Biotechnol., 99, 2015
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4Z2R
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4Z2T
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3NQ1
 | | Crystal Structure of Tyrosinase from Bacillus megaterium in complex with inhibitor kojic acid | | 分子名称: | 5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE, COPPER (II) ION, Tyrosinase, ... | | 著者 | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | | 登録日 | 2010-06-29 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | First structures of an active bacterial tyrosinase reveal copper plasticity.
J.Mol.Biol., 405, 2011
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3NQ5
 | | Crystal Structure of Tyrosinase from Bacillus megaterium R209H mutant | | 分子名称: | COPPER (II) ION, Tyrosinase, ZINC ION | | 著者 | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | | 登録日 | 2010-06-29 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | First structures of an active bacterial tyrosinase reveal copper plasticity.
J.Mol.Biol., 405, 2011
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3NQ0
 | | Crystal Structure of Tyrosinase from Bacillus megaterium crystallized in the absence of Zinc | | 分子名称: | COPPER (II) ION, Tyrosinase | | 著者 | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | | 登録日 | 2010-06-29 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | First structures of an active bacterial tyrosinase reveal copper plasticity.
J.Mol.Biol., 405, 2011
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3NPY
 | | Crystal Structure of Tyrosinase from Bacillus megaterium soaked in CuSO4 | | 分子名称: | CHLORIDE ION, COPPER (II) ION, Tyrosinase, ... | | 著者 | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | | 登録日 | 2010-06-29 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.192 Å) | | 主引用文献 | First structures of an active bacterial tyrosinase reveal copper plasticity.
J.Mol.Biol., 405, 2011
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