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PDB: 54 件
3KGQ
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BU of 3kgq by Molmil
Carboxypeptidase A liganded to an organic small-molecule: conformational changes
分子名称: ACETONE, CITRIC ACID, Carboxypeptidase A1, ...
著者Fernandez, D, Boix, E, Pallares, I, Aviles, F.X, Vendrell, J.
登録日2009-10-29
公開日2010-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Functional Analysis of the Complex between Citrate and the Zinc Peptidase Carboxypeptidase A
Enzyme Res, 2011, 2011
8GKQ
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Crystal Structure Analysis of Aspergillus fumigatus alkaline protease
分子名称: 1,2-ETHANEDIOL, Alkaline protease 1, CALCIUM ION, ...
著者Fernandez, D, Diec, D.D.L, Guo, W, Russi, S.
登録日2023-03-20
公開日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision.
Sci Rep, 13, 2023
8GKO
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BU of 8gko by Molmil
Crystal Structure Analysis of Aspergillus fumigatus alkaline protease
分子名称: 1,2-ETHANEDIOL, Alkaline protease 1, FORMYL GROUP, ...
著者Fernandez, D, Diec, D.D.L, Guo, W, Russi, S.
登録日2023-03-20
公開日2023-11-01
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision.
Sci Rep, 13, 2023
8GKP
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Crystal Structure Analysis of Aspergillus fumigatus alkaline protease
分子名称: Alkaline protease 1, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ...
著者Fernandez, D, Diec, D.D.L, Guo, W, Russi, S.
登録日2023-03-20
公開日2023-11-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision.
Sci Rep, 13, 2023
6W8E
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BU of 6w8e by Molmil
Crystal Structure Analysis of Space-grown Lysozyme
分子名称: CHLORIDE ION, Lysozyme
著者Fernandez, D, Russi, S.
登録日2020-03-20
公開日2020-04-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Protein structural changes on a CubeSat under rocket acceleration profile.
NPJ Microgravity, 6, 2020
6W7P
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BU of 6w7p by Molmil
Crystal Structure Analysis of Space-grown Lysozyme - Ground experiment
分子名称: CHLORIDE ION, Lysozyme, SODIUM ION
著者Fernandez, D, Russi, S.
登録日2020-03-19
公開日2020-04-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Protein structural changes on a CubeSat under rocket acceleration profile.
NPJ Microgravity, 6, 2020
6DNK
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BU of 6dnk by Molmil
Human Stimulator of Interferon Genes
分子名称: Stimulator of interferon genes protein, cGAMP
著者Fernandez, D, Li, L, Ergun, S.L.
登録日2018-06-06
公開日2019-03-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition.
Cell, 178, 2019
6CFF
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BU of 6cff by Molmil
Stimulator of Interferon Genes Human
分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Stimulator of interferon genes protein
著者Fernandez, D, Li, L, Ergun, S.L.
登録日2018-02-14
公開日2019-03-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.396 Å)
主引用文献STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition.
Cell, 178, 2019
6CY7
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BU of 6cy7 by Molmil
Human Stimulator of Interferon Genes
分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, GLYCEROL, IMIDAZOLE, ...
著者Fernandez, D, Li, L, Ergun, S.L.
登録日2018-04-04
公開日2019-03-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition.
Cell, 178, 2019
7MJC
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BU of 7mjc by Molmil
Crystal Structure Analysis of ALDH1B1
分子名称: Aldehyde dehydrogenase X, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Fernandez, D, Chen, J.K.
登録日2021-04-20
公開日2022-06-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Inhibitors targeted to aldehyde dehydrogenase
Nat.Chem.Biol., 2022
7MJD
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Crystal Structure Analysis of ALDH1B1
分子名称: 8-(2-methoxyphenyl)-10-(4-phenylphenyl)-1$l^{4},8-diazabicyclo[5.3.0]deca-1(7),9-diene, Aldehyde dehydrogenase X, mitochondrial, ...
著者Fernandez, D, Chen, J.K.
登録日2021-04-20
公開日2022-06-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Inhibitors targeted to aldehyde dehydrogenase
Nat.Chem.Biol., 2022
5A52
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The crystal structure of Arabidopsis thaliana CAR1 in complex with one calcium ion
分子名称: CALCIUM ION, CALCIUM-DEPENDENT LIPID-BINDING DOMAIN-CONTAINING PROTEIN, GLYCEROL, ...
著者Fernandez, D, Marquez, J.A.
登録日2015-06-16
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Calcium-Dependent Oligomerization of Car Proteins at Cell Membrane Modulates Aba Signaling.
Proc.Natl.Acad.Sci.USA, 113, 2016
7N1S
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BU of 7n1s by Molmil
Crystal Structure Analysis of Xac Nucleotide Pyrophosphatase/Phosphodiesterase
分子名称: Phosphodiesterase-nucleotide pyrophosphatase, TETRAETHYLENE GLYCOL, ZINC ION
著者Fernandez, D, Li, L, Brown, J.A, Carozza, J.A.
登録日2021-05-28
公開日2022-06-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献ENPP1's regulation of extracellular cGAMP is a ubiquitous mechanism of attenuating STING signaling.
Proc.Natl.Acad.Sci.USA, 119, 2022
6NQT
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GalNac-T2 soaked with UDP-sugar
分子名称: MANGANESE (II) ION, Polypeptide N-acetylgalactosaminyltransferase 2, [[(2~{R},3~{S},4~{R},5~{R})-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R},6~{R})-3-(hex-5-ynoylamino)-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl] hydrogen phosphate
著者Fernandez, D, Bertozzi, C.R, Schumann, B, Agbay, A.
登録日2019-01-21
公開日2020-01-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells.
Mol.Cell, 78, 2020
7MW8
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BU of 7mw8 by Molmil
Crystal Structure Analysis of Xac Nucleotide Pyrophosphatase/Phosphodiesterase
分子名称: Phosphodiesterase-nucleotide pyrophosphatase, ZINC ION, pApG
著者Fernandez, D, Li, L, Brown, J.A.
登録日2021-05-15
公開日2022-05-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献ENPP1's regulation of extracellular cGAMP is a ubiquitous mechanism of attenuating STING signaling.
Proc.Natl.Acad.Sci.USA, 119, 2022
3HUV
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BU of 3huv by Molmil
Carboxypeptidase A liganded to an organic small-molecule: conformational changes
分子名称: Carboxypeptidase A1 (Pancreatic), ZINC ION
著者Fernandez, D, Boix, E, Aviles, F.X, Vendrell, J.
登録日2009-06-15
公開日2010-06-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Carboxypeptidase A liganded to an organic small-molecule: conformational changes
To be Published
3HLP
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BU of 3hlp by Molmil
Carboxypeptidase A liganded to an organic small-molecule: conformational changes
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Carboxypeptidase A1 (Pancreatic), ...
著者Fernandez, D.
登録日2009-05-28
公開日2010-06-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Carboxypeptidase A liganded to an organic small-molecule: conformational
To be Published
3GLJ
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BU of 3glj by Molmil
A polymorph of carboxypeptidase B zymogen structure
分子名称: Carboxypeptidase B, GLYCEROL, ZINC ION
著者Fernandez, D.
登録日2009-03-12
公開日2009-10-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Analysis of a new crystal form of procarboxypeptidase B: further insights into the catalytic mechanism
Biopolymers, 2009
3I1U
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BU of 3i1u by Molmil
Carboxypeptidase A Inhibited by a Thiirane Mechanism-Based inactivator
分子名称: (2S,3R)-2-benzyl-3-sulfanylbutanoic acid, Carboxypeptidase A1 (Pancreatic), GLYCEROL, ...
著者Fernandez, D.
登録日2009-06-28
公開日2009-11-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.391 Å)
主引用文献The X-ray structure of carboxypeptidase A inhibited by a thiirane mechanism-based inhibitor
Chem.Biol.Drug Des., 75, 2010
7RAD
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BU of 7rad by Molmil
Crystal Structure Analysis of ALDH1B1
分子名称: 1,2-ETHANEDIOL, 3-(2-methoxyphenyl)-1-(4-phenylphenyl)-6,7,8,9-tetrahydro-5~{H}-imidazo[1,2-a][1,3]diazepine, Aldehyde dehydrogenase X, ...
著者Fernandez, D, Chen, J.K.
登録日2021-07-01
公開日2022-06-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Inhibitors targeted to aldehyde dehydrogenase
Nat.Chem.Biol., 2022
4K90
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Extracellular metalloproteinase from Aspergillus
分子名称: BORIC ACID, CALCIUM ION, Extracellular metalloproteinase mep, ...
著者Fernandez, D, Russi, S, Vendrell, J, Monod, M, Pallares, I.
登録日2013-04-19
公開日2013-10-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A functional and structural study of the major metalloprotease secreted by the pathogenic fungus Aspergillus fumigatus.
Acta Crystallogr.,Sect.D, 69, 2013
7SCI
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BU of 7sci by Molmil
AM0627 metallopeptidase from Akkermansia muciniphila
分子名称: CHLORIDE ION, FORMIC ACID, Peptidase M60 domain-containing protein, ...
著者Fernandez, D, Bertozzi, C.R, Shon, D.J.
登録日2021-09-28
公開日2022-04-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences.
J.Biol.Chem., 298, 2022
8U45
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BU of 8u45 by Molmil
Crystal Structure Analysis of Aspergillus fumigatus alkaline protease
分子名称: Alkaline protease 1, CALCIUM ION, CHLORIDE ION, ...
著者Fernandez, D, Diec, D.D.L, Guo, W, Russi, S.
登録日2023-09-08
公開日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision.
Sci Rep, 13, 2023
6XKD
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BU of 6xkd by Molmil
Structure of ligand-bound mouse cGAMP hydrolase ENPP1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Fernandez, D, Li, L.
登録日2020-06-26
公開日2021-06-02
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure-Aided Development of Small-Molecule Inhibitors of ENPP1, the Extracellular Phosphodiesterase of the Immunotransmitter cGAMP.
Cell Chem Biol, 27, 2020
2V77
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Crystal Structure of Human Carboxypeptidase A1
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CARBOXYPEPTIDASE A1, OCTANE-1,3,5,7-TETRACARBOXYLIC ACID, ...
著者Pallares, I, Fernandez, D, Comellas-Bigler, M, Fernandez-Recio, J, Ventura, S, Aviles, F.X, Vendrell, J.
登録日2007-07-27
公開日2008-07-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.603 Å)
主引用文献Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid).
Acta Crystallogr. D Biol. Crystallogr., D64, 2008

 

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