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PDB: 39 件

5O3O
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Pronase-treated paired helical filament in Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2017-05-24
公開日2017-07-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5O3T
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Straight filament in Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Fitzpatrick, A.W.P, Falcon, B, He, S, Murzin, A.G, Murshudov, G, Garringer, H.G, Crowther, R.A, Ghetti, B, Goedert, M, Scheres, S.H.W.
登録日2017-05-24
公開日2017-07-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
8BGS
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Tau Paired Helical Filament from Extracellular Vesicles from Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Behr, T.S, Ryskeldi-Falcon, B.
登録日2022-10-28
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.
Biorxiv, 2023
7NRV
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Paired helical filament from Alzheimer's disease with PET ligand APN-1607
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
8BGV
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Tau Paired Helical Filament from Cellular Fraction of Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Behr, T.S, Ryskeldi-Falcon, B.
登録日2022-10-28
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.
Biorxiv, 2023
7NRT
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Conformation 2 of straight filament from primary age-related tauopathy brain
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRX
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BU of 7nrx by Molmil
Straight filament from Alzheimer's disease with PET ligand APN-1607
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRS
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Conformation 1 of straight filament from primary age-related tauopathy brain
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
7NRQ
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BU of 7nrq by Molmil
Paired helical filament from primary age-related tauopathy brain
分子名称: Microtubule-associated protein tau
著者Shi, Y, Murzin, A.G, Falcon, B, Epstein, A, Machin, J, Tempest, P, Newell, K.L, Vidal, R, Garringer, H.J, Sahara, N, Higuchi, M, Ghetti, B, Jang, M, Scheres, S.H.W, Goedert, M.
登録日2021-03-04
公開日2021-03-24
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141, 2021
6QJQ
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Cryo-EM structure of heparin-induced 2N3R tau filaments
分子名称: Microtubule-associated protein tau
著者Zhang, W, Falcon, B, Murzin, A.G, Fan, J, Crowther, R.A, Goedert, M, Scheres, S.H.W.
登録日2019-01-24
公開日2019-02-20
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
8ONS
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BU of 8ons by Molmil
TAF15 amyloid fold in atypical FTLD - Individual 1
分子名称: TATA-binding protein-associated factor 2N
著者Tetter, S, Ryskeldi-Falcon, B.
登録日2023-04-03
公開日2023-12-06
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (1.97 Å)
主引用文献TAF15 amyloid filaments in frontotemporal lobar degeneration.
Nature, 625, 2024
6TJO
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Cryo-EM structure of TypeI tau filaments extracted from the brains of individuals with Corticobasal degeneration
分子名称: Microtubule-associated protein tau
著者Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W.
登録日2019-11-26
公開日2020-02-05
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
6TJX
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Cryo-EM structure of TypeII tau filaments extracted from the brains of individuals with Corticobasal degeneration
分子名称: Microtubule-associated protein tau
著者Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W.
登録日2019-11-27
公開日2020-02-05
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
8OTI
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BU of 8oti by Molmil
CTE typeIII tau filament
分子名称: Microtubule-associated protein tau
著者Tetter, S, Qi, C, Ryskeldi-Falcon, B, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
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件を2024-06-12に公開中

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