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PDB: 23 results
1YS4
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BU of 1ys4 by Molmil
Structure of Aspartate-Semialdehyde Dehydrogenase from Methanococcus jannaschii
Descriptor: Aspartate-semialdehyde dehydrogenase, MALONIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Faehnle, C.R, Ohren, J.F, Viola, R.E.
Deposit date:2005-02-07
Release date:2005-11-01
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:A New Branch in the Family: Structure of Aspartate-beta-semialdehyde Dehydrogenase from Methanococcus jannaschii
J.Mol.Biol., 353, 2005
4PMW
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BU of 4pmw by Molmil
Structure of mouse Dis3L2 in complex with oligoU RNA substrate
Descriptor: DIS3-like exonuclease 2, MAGNESIUM ION, U-U-U-U-U-U-U-U-U-U-U-U-U-U
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2014-05-22
Release date:2014-07-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway.
Nature, 514, 2014
4KRE
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BU of 4kre by Molmil
Structure of Human Argonaute-1 bound to endogenous Sf9 RNA
Descriptor: Protein argonaute-1, RNA (5'-R(P*AP*AP*UP*AP*UP*UP*AP*AP*A*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
Authors:Faehnle, C.R, Elkayam, E, Joshua-Tor, L.
Deposit date:2013-05-16
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.754 Å)
Cite:The making of a slicer: activation of human argonaute-1.
Cell Rep, 3, 2013
4KRF
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BU of 4krf by Molmil
Structure of Human Argonaute-1 let-7 complex
Descriptor: Protein argonaute-1, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*UP*U)-3')
Authors:Faehnle, C.R, Elkayam, E, Joshua-Tor, L.
Deposit date:2013-05-16
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:The making of a slicer: activation of human argonaute-1.
Cell Rep, 3, 2013
5W0M
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BU of 5w0m by Molmil
Structure of human TUT7 catalytic module (CM) in complex with U5 RNA
Descriptor: IODIDE ION, SULFATE ION, Terminal uridylyltransferase 7, ...
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-31
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
5W0B
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BU of 5w0b by Molmil
Structure of human TUT7 catalytic module (CM)
Descriptor: IODIDE ION, SULFATE ION, Terminal uridylyltransferase 7, ...
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-30
Release date:2017-06-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.614 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
5W0O
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BU of 5w0o by Molmil
Structure of human TUT7 catalytic module (CM) in complex with dsRNA
Descriptor: Terminal uridylyltransferase 7, URIDINE 5'-TRIPHOSPHATE, double-stranded RNA
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-31
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.488 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
5W0N
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BU of 5w0n by Molmil
Structure of human TUT7 catalytic module (CM) in complex with UMPNPP and U2 RNA
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, IODIDE ION, MAGNESIUM ION, ...
Authors:Faehnle, C.R, Walleshauser, J, Joshua-Tor, L.
Deposit date:2017-05-31
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
Nat. Struct. Mol. Biol., 24, 2017
2GYY
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BU of 2gyy by Molmil
Structure of aspartate semialdehyde dehydrogenase (ASADH) from Streptococcus pneumoniae
Descriptor: Aspartate beta-semialdehyde dehydrogenase
Authors:Faehnle, C.R, Le Coq, J, Liu, X, Viola, R.E.
Deposit date:2006-05-10
Release date:2006-08-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria.
J.Biol.Chem., 281, 2006
2HMF
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BU of 2hmf by Molmil
Structure of a Threonine Sensitive Aspartokinase from Methanococcus jannaschii Complexed with Mg-ADP and Aspartate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ASPARTIC ACID, MAGNESIUM ION, ...
Authors:Faehnle, C.R, Viola, R.E.
Deposit date:2006-07-11
Release date:2006-10-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The initial step in the archaeal aspartate biosynthetic pathway catalyzed by a monofunctional aspartokinase.
Acta Crystallogr.,Sect.F, 62, 2006
2GZ1
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BU of 2gz1 by Molmil
Structure of Aspartate Semialdehyde Dehydrogenase (ASADH) from Streptococcus pneumoniae complexed with NADP
Descriptor: Aspartate beta-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Faehnle, C.R, Le Coq, J, Liu, X, Viola, R.E.
Deposit date:2006-05-10
Release date:2006-08-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria.
J.Biol.Chem., 281, 2006
2GZ3
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BU of 2gz3 by Molmil
Structure of Aspartate Semialdehyde Dehydrogenase (ASADH) from Streptococcus pneumoniae complexed with NADP and aspartate-semialdehyde
Descriptor: (2R)-2-AMINO-4-OXOBUTANOIC ACID, Aspartate beta-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Faehnle, C.R, Le Coq, J, Liu, X, Viola, R.E.
Deposit date:2006-05-10
Release date:2006-08-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria.
J.Biol.Chem., 281, 2006
2GZ2
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BU of 2gz2 by Molmil
Structure of Aspartate Semialdehyde Dehydrogenase (ASADH) from Streptococcus pneumoniae complexed with 2',5'-ADP
Descriptor: ADENOSINE-2'-5'-DIPHOSPHATE, Aspartate beta-semialdehyde dehydrogenase
Authors:Faehnle, C.R, Le Coq, J, Liu, X, Viola, R.E.
Deposit date:2006-05-10
Release date:2006-08-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria.
J.Biol.Chem., 281, 2006
2QZ9
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BU of 2qz9 by Molmil
crystal structure of aspartate semialdehyde dehydrogenase II from vibrio cholerae
Descriptor: Aspartate-semialdehyde dehydrogenase
Authors:Viola, R.E, Liu, X, Ohren, J.F, Faehnle, C.R.
Deposit date:2007-08-16
Release date:2008-04-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.
Acta Crystallogr.,Sect.D, 64, 2008
2R00
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BU of 2r00 by Molmil
crystal structure of aspartate semialdehyde dehydrogenase II complexed with ASA from vibrio cholerae
Descriptor: 2,2'-oxydiacetic acid, Aspartate-semialdehyde dehydrogenase
Authors:Viola, R.E, Liu, X, Ohren, J.F, Faehnle, C.R.
Deposit date:2007-08-17
Release date:2008-04-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.
Acta Crystallogr.,Sect.D, 64, 2008
1PR3
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BU of 1pr3 by Molmil
Crystal Structure of the R103K Mutant of Aspartate Semialdehyde dehydrogenase from Haemophilus influenzae
Descriptor: Aspartate semialdehyde dehydrogenase, PHOSPHATE ION
Authors:Blanco, J, Moore, R.A, Faehnle, C.R, Coe, D.M, Viola, R.E.
Deposit date:2003-06-19
Release date:2004-07-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr.,Sect.D, 60, 2004
1PU2
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BU of 1pu2 by Molmil
Crystal Structure of the K246R Mutant of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae
Descriptor: Aspartate-semialdehyde dehydrogenase
Authors:Blanco, J, Moore, R.A, Faehnle, C.R, Coe, D.M, Viola, R.E.
Deposit date:2003-06-23
Release date:2004-07-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr.,Sect.D, 60, 2004
5W6V
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BU of 5w6v by Molmil
The Structure of human Argonaute-1 in complex with the hook motif of human GW182
Descriptor: Protein argonaute-1, RNA (5'-R(P*AP*AP*UP*AP*UP*UP*AP*AP*AP*A)-3'), Trinucleotide repeat-containing gene 6A protein
Authors:Elkayam, E, Faehnle, C.R, Joshua-Tor, L.
Deposit date:2017-06-17
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.828 Å)
Cite:Multivalent Recruitment of Human Argonaute by GW182.
Mol. Cell, 67, 2017
1Q2X
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BU of 1q2x by Molmil
Crystal Structure of the E243D Mutant of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae bound with substrate aspartate semialdehyde
Descriptor: Aspartate-semialdehyde dehydrogenase
Authors:Blanco, J, Moore, R.A, Faehnle, C.R, Coe, D.M, Viola, R.E.
Deposit date:2003-07-26
Release date:2004-07-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr.,Sect.D, 60, 2004
1PQP
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BU of 1pqp by Molmil
Crystal Structure of the C136S Mutant of Aspartate Semialdehyde Dehydrogenase from Haemophilus influenzae Bound with Aspartate Semialdehyde and Phosphate
Descriptor: Aspartate-semialdehyde dehydrogenase, L-HOMOSERINE, PHOSPHATE ION
Authors:Blanco, J, Moore, R.A, Faehnle, C.R, Viola, R.E.
Deposit date:2003-06-18
Release date:2004-08-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr.,Sect.D, 60, 2004
1PS8
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BU of 1ps8 by Molmil
Crystal Structure of the R270K Mutant of Aspartate Semialdehyde dehydrogenase from Haemophilus influenzae
Descriptor: Aspartate semialdehyde dehydrogenase
Authors:Blanco, J, Moore, R.A, Faehnle, C.R, Coe, D.M, Viola, R.E.
Deposit date:2003-06-20
Release date:2004-07-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr.,Sect.D, 60, 2004
3Q11
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BU of 3q11 by Molmil
Crystals Structure of Aspartate beta-Semialdehyde Dehydrogenase from Streptococcus pneumoniae with NADP and aspartyl beta-difluorophosphonate
Descriptor: 1,2-ETHANEDIOL, 5,5-difluoro-4-oxo-5-phosphono-D-norvaline, Aspartate-semialdehyde dehydrogenase, ...
Authors:Pavlovsky, A.G, Viola, R.E, Faehnle, C.R.
Deposit date:2010-12-16
Release date:2012-01-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family.
Chem.Biol.Drug Des., 79, 2012
3PYL
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BU of 3pyl by Molmil
Crystal structure of aspartate beta-semialdehide dehydrogenase from Streptococcus pneumoniae with D-2,3-diaminopropionate
Descriptor: 3-amino-D-alanine, Aspartate-semialdehyde dehydrogenase
Authors:Pavlovsky, A.G, Liu, X, Faehnle, C.R, Potente, N, Viola, R.E.
Deposit date:2010-12-13
Release date:2012-01-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family.
Chem.Biol.Drug Des., 79, 2012

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