6E93
| Crystal Structure of ZBTB38 C-terminal Zinc Fingers 6-9 in complex with methylated DNA | 分子名称: | DNA (5'-D(*GP*CP*AP*CP*TP*CP*AP*TP*(DCM)P*GP*GP*(DCM)P*GP*CP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*(DCM)P*GP*CP*(DCM)P*GP*AP*TP*GP*AP*GP*TP*GP*C)-3'), ZINC ION, ... | 著者 | Hudson, N.O, Whitby, F.G, Buck-Koehntop, B.A. | 登録日 | 2018-07-31 | 公開日 | 2018-11-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | 主引用文献 | Structural insights into methylated DNA recognition by the C-terminal zinc fingers of the DNA reader protein ZBTB38. J. Biol. Chem., 293, 2018
|
|
4FQ9
| Crystal Structure of 3-hydroxydecanoyl-Acyl Carrier Protein Dehydratase (FabA) from Pseudomonas aeruginosa | 分子名称: | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, GLYCEROL, PHOSPHATE ION | 著者 | Moynie, L, Mcmahon, S.A, Duthie, F.G, Naismith, J.H. | 登録日 | 2012-06-25 | 公開日 | 2013-03-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Structural insights into the mechanism and inhibition of the beta-hydroxydecanoyl-acyl carrier protein dehydratase from Pseudomonas aeruginosa J.Mol.Biol., 425, 2013
|
|
7C6U
| Crystal structure of SARS-CoV-2 complexed with GC376 | 分子名称: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase | 著者 | Fu, L, Feng, Y, Qi, J, Gao, F.G. | 登録日 | 2020-05-22 | 公開日 | 2020-09-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease. Nat Commun, 11, 2020
|
|
3OYX
| Haloferax volcanii Malate Synthase Magnesium/Glyoxylate Complex | 分子名称: | CHLORIDE ION, GLYOXYLIC ACID, MAGNESIUM ION, ... | 著者 | Howard, B.R, Bracken, C, Neighbor, A, Thomas, G, Lamlenn, K.K, Schubert, H.L, Whitby, F.G. | 登録日 | 2010-09-24 | 公開日 | 2011-06-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G. Bmc Struct.Biol., 11, 2011
|
|
3OYZ
| Haloferax volcanii Malate Synthase Pyruvate/Acetyl-CoA Ternary Complex | 分子名称: | ACETYL COENZYME *A, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Howard, B.R, Bracken, C, Neighbor, A, Thomas, G, Lamlenn, K.K, Schubert, H.L, Whitby, F.G. | 登録日 | 2010-09-24 | 公開日 | 2011-06-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G. Bmc Struct.Biol., 11, 2011
|
|
3PB0
| |
3PUG
| Haloferax volcanii Malate Synthase Native at 3mM Glyoxylate | 分子名称: | CHLORIDE ION, GLYOXYLIC ACID, MAGNESIUM ION, ... | 著者 | Howard, B.R, Bracken, C.D, Neighbor, A.M, Thomas, G.C, Lamlenn, K.K, Schubert, H.L, Whitby, F.G. | 登録日 | 2010-12-04 | 公開日 | 2011-06-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G. Bmc Struct.Biol., 11, 2011
|
|
3RBQ
| Co-crystal structure of human UNC119 (retina gene 4) and an N-terminal Transducin-alpha mimicking peptide | 分子名称: | Guanine nucleotide-binding protein G(t) subunit alpha-1, Protein unc-119 homolog A | 著者 | Constantine, R, Whitby, F.G, Hill, C.P, Baehr, W. | 登録日 | 2011-03-29 | 公開日 | 2011-06-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | UNC119 is required for G protein trafficking in sensory neurons. Nat.Neurosci., 14, 2011
|
|
3PB2
| |
6LA6
| |
6LAP
| |
6NBI
| Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein | 分子名称: | CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. | 登録日 | 2018-12-07 | 公開日 | 2019-04-17 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
|
|
6NBF
| Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein | 分子名称: | CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. | 登録日 | 2018-12-07 | 公開日 | 2019-04-17 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
|
|
6NBH
| Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein | 分子名称: | CHOLESTEROL, Gs protein alpha subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhao, L.-H, Ma, S, Sutkeviciute, I, Shen, D.-D, Zhou, X.E, de Waal, P.P, Li, C.-Y, Kang, Y, Clark, L.J, Jean-Alphonse, F.G, White, A.D, Xiao, K, Yang, D, Jiang, Y, Watanabe, T, Gardella, T.J, Melcher, K, Wang, M.-W, Vilardaga, J.-P, Xu, H.E, Zhang, Y. | 登録日 | 2018-12-07 | 公開日 | 2019-04-17 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364, 2019
|
|
1JPH
| Ile260Thr mutant of Human UroD, human uroporphyrinogen III decarboxylase | 分子名称: | UROPORPHYRINOGEN DECARBOXYLASE | 著者 | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | 登録日 | 2001-08-02 | 公開日 | 2001-12-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase. Blood, 98, 2001
|
|
1JPK
| Gly156Asp mutant of Human UroD, human uroporphyrinogen III decarboxylase | 分子名称: | UROPORPHYRINOGEN DECARBOXYLASE | 著者 | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | 登録日 | 2001-08-02 | 公開日 | 2001-12-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase. Blood, 98, 2001
|
|
1JPI
| Phe232Leu mutant of human UROD, human uroporphyrinogen III decarboxylase | 分子名称: | UROPORPHYRINOGEN DECARBOXYLASE | 著者 | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | 登録日 | 2001-08-02 | 公開日 | 2001-12-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase. Blood, 98, 2001
|
|
1ATL
| Structural interaction of natural and synthetic inhibitors with the VENOM METALLOPROTEINASE, ATROLYSIN C (FORM-D) | 分子名称: | CALCIUM ION, O-methyl-N-[(2S)-4-methyl-2-(sulfanylmethyl)pentanoyl]-L-tyrosine, Snake venom metalloproteinase atrolysin-D, ... | 著者 | Zhang, D, Botos, I, Gomis-Rueth, F.-X, Doll, R, Blood, C, Njoroge, F.G, Fox, J.W, Bode, W, Meyer, E.F. | 登録日 | 1995-05-26 | 公開日 | 1995-10-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural interaction of natural and synthetic inhibitors with the venom metalloproteinase, atrolysin C (form d). Proc.Natl.Acad.Sci.USA, 91, 1994
|
|
1AK5
| |
7TXE
| |
7U2V
| |
5Y2K
| A human antibody AF4H1L1 | 分子名称: | a group 2 HA binding antibody AF4H1K1 Fab heavy chain, a group 2 HA binding antibody AF4H1K1 Fab light chain | 著者 | Xiao, H, Qi, J, Gao, F.G. | 登録日 | 2017-07-26 | 公開日 | 2019-01-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | An H3-clade neutralizing antibody screened from an H7N9 patient that binds group 2 influenza A hemagglutinins To Be Published
|
|
5Y2M
| |
5Y2L
| |
7UJV
| Structure of PHD2 in complex with HIF2a-CODD | 分子名称: | Egl nine homolog 1, Endothelial PAS domain-containing protein 1, FE (III) ION, ... | 著者 | Ferens, F.G, Tarade, D, Lee, J.E, Ohh, M. | 登録日 | 2022-03-31 | 公開日 | 2023-04-05 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Deficiency in PHD2-mediated hydroxylation of HIF2 alpha underlies Pacak-Zhuang syndrome. Commun Biol, 7, 2024
|
|