1K6K
 
 | | Crystal Structure of ClpA, an AAA+ Chaperone-like Regulator of ClpAP protease implication to the functional difference of two ATPase domains | | Descriptor: | ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA | | Authors: | Guo, F, Maurizi, M.R, Esser, L, Xia, D. | | Deposit date: | 2001-10-16 | | Release date: | 2002-09-27 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of ClpA, an HSP100 chaperone and regulator of ClpAP protease
J.Biol.Chem., 277, 2002
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4F33
 | | Crystal Structure of therapeutic antibody MORAb-009 | | Descriptor: | MORAb-009 FAB heavy chain, MORAb-009 FAB light chain, TETRAETHYLENE GLYCOL | | Authors: | Xia, D, Ma, J, Tang, W.K, Esser, L. | | Deposit date: | 2012-05-08 | | Release date: | 2012-07-11 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.749 Å) | | Cite: | Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.
J.Biol.Chem., 287, 2012
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7U9J
 | | Crystal structure of Mesothelin-207 fragment | | Descriptor: | GLYCEROL, Isoform 3 of Mesothelin, SULFATE ION | | Authors: | Zhan, J, Esser, L, Lin, D, Tang, W.K, Xia, D. | | Deposit date: | 2022-03-10 | | Release date: | 2023-02-01 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies.
Cancer Res Commun, 3, 2023
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1MBU
 | | Crystal Structure Analysis of ClpSN heterodimer | | Descriptor: | ATP-Dependent clp Protease ATP-Binding Subunit clp A, BIS-(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE YTTRIUM, CHLORIDE ION, ... | | Authors: | Guo, F, Esser, L, Singh, S.K, Maurizi, M.R, Xia, D. | | Deposit date: | 2002-08-03 | | Release date: | 2002-12-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of the Heterodimeric Complex of the Adaptor, ClpS, with the N-domain of the AAA+ Chaperone, ClpA
J.Biol.Chem., 277, 2002
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1MBX
 | | CRYSTAL STRUCTURE ANALYSIS OF ClpSN WITH TRANSITION METAL ION BOUND | | Descriptor: | ATP-Dependent clp Protease ATP-Binding Subunit clp A, BIS-(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE YTTRIUM, CHLORIDE ION, ... | | Authors: | Guo, F, Esser, L, Singh, S.K, Maurizi, M.R, Xia, D. | | Deposit date: | 2002-08-03 | | Release date: | 2002-12-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Crystal Structure of the Heterodimeric Complex of the Adaptor, ClpS, with the N-domain of the AAA+ Chaperone, ClpA
J.Biol.Chem., 277, 2002
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4F3F
 | | Crystal Structure of Msln7-64 MORAb-009 FAB complex | | Descriptor: | MORAb-009 Fab heavy chain, MORAb-009 Fab light chain, Mesothelin | | Authors: | Xia, D, Pastan, I, Ma, J, Tang, W.K, Esser, L. | | Deposit date: | 2012-05-09 | | Release date: | 2012-07-11 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights.
J.Biol.Chem., 287, 2012
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1MBV
 | | CRYSTAL STRUCTURE ANALYSIS OF ClpSN HETERODIMER TETRAGONAL FORM | | Descriptor: | ATP-Dependent clp Protease ATP-Binding Subunit clp A, Protein yljA | | Authors: | Guo, F, Esser, L, Singh, S.K, Maurizi, M.R, Xia, D. | | Deposit date: | 2002-08-03 | | Release date: | 2002-12-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Crystal Structure of the Heterodimeric Complex of the Adaptor, ClpS, with the N-domain of AAA+ Chaperone ClpA
J.Biol.Chem., 277, 2002
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1R6B
 | | High resolution crystal structure of ClpA | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ClpA protein, MAGNESIUM ION | | Authors: | Xia, D, Maurizi, M.R, Guo, F, Singh, S.K, Esser, L. | | Deposit date: | 2003-10-15 | | Release date: | 2004-08-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone.
J.Struct.Biol., 146, 2004
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1R6Q
 | | ClpNS with fragments | | Descriptor: | ATP-dependent Clp protease ATP-binding subunit clpA, ATP-dependent Clp protease adaptor protein clpS, BIS-(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE YTTRIUM, ... | | Authors: | Xia, D, Maurizi, M.R, Guo, F, Singh, S.K, Esser, L. | | Deposit date: | 2003-10-16 | | Release date: | 2005-02-15 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone.
J.Struct.Biol., 146, 2004
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1R6O
 | | ATP-dependent Clp protease ATP-binding subunit clpA/ATP-dependent Clp protease adaptor protein clpS | | Descriptor: | ATP-dependent Clp protease ATP-binding subunit clpA, ATP-dependent Clp protease adaptor protein clpS, BIS-(2-HYDROXYETHYL)AMINO-TRIS(HYDROXYMETHYL)METHANE YTTRIUM, ... | | Authors: | Xia, D, Maurizi, M.R, Guo, F, Singh, S.K, Esser, L. | | Deposit date: | 2003-10-15 | | Release date: | 2005-02-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Crystallographic investigation of peptide binding sites in the N-domain of the
ClpA chaperone
J.Struct.Biol., 146, 2004
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7U8C
 | | Crystal structure of Mesothelin C-terminal peptide-MORAb 15B6 FAB complex | | Descriptor: | MORab 15B6 Fab heavy chain, MORab 15B6 Fab light chain, Mesothelin, ... | | Authors: | Zhan, J, Esser, L, Xia, D. | | Deposit date: | 2022-03-08 | | Release date: | 2022-06-08 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Highly active CAR T cells that bind to a juxtamembrane region of mesothelin and are not blocked by shed mesothelin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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1R6C
 | | High resolution structure of ClpN | | Descriptor: | ATP-dependent Clp protease ATP-binding subunit clpA | | Authors: | Xia, D, Maurizi, M.R, Guo, F, Singh, S.K, Esser, L. | | Deposit date: | 2003-10-15 | | Release date: | 2005-02-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystallographic investigation of peptide binding sites in the N-domain of the
ClpA chaperone
J.Struct.Biol., 146, 2004
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2B4L
 | | Crystal structure of the binding protein OpuAC in complex with glycine betaine | | Descriptor: | 1,2-ETHANEDIOL, Glycine betaine-binding protein, TRIMETHYL GLYCINE | | Authors: | Horn, C, Sohn-Boesser, L, Breed, J, Welte, W, Schmitt, L, Bremer, E. | | Deposit date: | 2005-09-26 | | Release date: | 2006-03-21 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Molecular Determinants for Substrate Specificity of the Ligand-binding Protein OpuAC from Bacillus subtilis for the Compatible Solutes Glycine Betaine and Proline Betaine.
J.Mol.Biol., 357, 2006
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2B4M
 | | Crystal structure of the binding protein OpuAC in complex with proline betaine | | Descriptor: | 1,1-DIMETHYL-PROLINIUM, Glycine betaine-binding protein | | Authors: | Horn, C, Sohn-Boesser, L, Breed, J, Welte, W, Schmitt, L, Bremer, E. | | Deposit date: | 2005-09-26 | | Release date: | 2006-03-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Molecular Determinants for Substrate Specificity of the Ligand-binding Protein OpuAC from Bacillus subtilis for the Compatible Solutes Glycine Betaine and Proline Betaine.
J.Mol.Biol., 357, 2006
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2VUL
 | | Thermostable mutant of ENVIRONMENTALLY ISOLATED GH11 XYLANASE | | Descriptor: | DODECAETHYLENE GLYCOL, GH11 XYLANASE, SULFATE ION | | Authors: | Dumon, C, Varvak, A, Wall, M.A, Flint, J.E, Lewis, R.J, Lakey, J.H, Luginbuhl, P, Healey, S, Todaro, T, Desantis, G, Sun, M, Parra-Gessert, L, Tan, X, Weiner, D.P, Gilbert, H.J. | | Deposit date: | 2008-05-27 | | Release date: | 2008-06-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Engineering Hyperthermostability Into a Gh11 Xylanase is Mediated by Subtle Changes to Protein Structure.
J.Biol.Chem., 283, 2008
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2VUJ
 | | Environmentally isolated GH11 xylanase | | Descriptor: | GH11 XYLANASE, GLYCEROL | | Authors: | Dumon, C, Varvak, A, Wall, M.A, Flint, J.E, Lewis, R.J, Lakey, J.H, Luginbuhl, P, Healey, S, Todaro, T, DeSantis, G, Sun, M, Parra-Gessert, L, Tan, X, Weiner, D.P, Gilbert, H.J. | | Deposit date: | 2008-05-26 | | Release date: | 2008-06-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Engineering Hyperthermostability Into a Gh11 Xylanase is Mediated by Subtle Changes to Protein Structure.
J.Biol.Chem., 283, 2008
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1I8E
 | | NMR ENSEMBLE OF ION-SELECTIVE LIGAND A22 FOR PLATELET INTEGRIN ALPHAIIB-BETA3 | | Descriptor: | ION-SELECTIVE LIGAND A22 | | Authors: | Smith, J.W, Le Calvez, H, Parra-Gessert, L, Preece, N.E, Jia, X, Assa-Munt, N. | | Deposit date: | 2001-03-13 | | Release date: | 2002-07-10 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Selection and structure of ion-selective ligands for platelet integrin alpha IIb(beta) 3.
J.Biol.Chem., 277, 2002
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1I93
 | | NMR ENSEMBLE OF ION-SELECTIVE LIGAND D16 FOR PLATELET INTEGRIN ALPHAIIB-BETA3 | | Descriptor: | ION-SELECTIVE LIGAND D16 | | Authors: | Smith, J.W, Le Calvez, H, Parra-Gessert, L, Preece, N.E, Jia, X, Assa-Munt, N. | | Deposit date: | 2001-03-17 | | Release date: | 2002-07-10 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Selection and structure of ion-selective ligands for platelet integrin alpha IIb(beta) 3.
J.Biol.Chem., 277, 2002
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1I98
 | | NMR ENSEMBLE OF ION-SELECTIVE LIGAND D18 FOR PLATELET INTEGRIN ALPHAIIB-BETA3 | | Descriptor: | ION-SELECTIVE LIGAND D18 | | Authors: | Smith, J.W, Le Calvez, H, Parra-Gessert, L, Preece, N.E, Jia, X, Assa-Munt, N. | | Deposit date: | 2001-03-18 | | Release date: | 2002-07-10 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Selection and structure of ion-selective ligands for platelet integrin alpha IIb(beta) 3.
J.Biol.Chem., 277, 2002
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1I6Y
 | | NMR ENSEMBLE OF ION-SELECTIVE LIGAND A1 FOR PLATELET INTEGRIN ALPHAIIB-BETA3 | | Descriptor: | ION-SELECTIVE LIGAND A1 | | Authors: | Smith, J.W, Le Calvez, H, Parra-Gessert, L, Preece, N.E, Jia, X, Assa-Munt, N. | | Deposit date: | 2001-03-06 | | Release date: | 2002-07-10 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Selection and structure of ion-selective ligands for platelet integrin alpha IIb(beta) 3.
J.Biol.Chem., 277, 2002
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