5W20
 
 | | Crystal Structure of inosine-substituted duplex DNA | | 分子名称: | DNA (5'-D(*CP*CP*AP*IP*IP*CP*CP*TP*GP*G)-3'), MAGNESIUM ION | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2017-06-05 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Comparative analysis of inosine-substituted duplex DNA by circular dichroism and X-ray crystallography.
J. Biomol. Struct. Dyn., 36, 2018
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2RF3
 | | Crystal Structure of Tricyclo-DNA: An Unusual Compensatory Change of Two Adjacent Backbone Torsion Angles | | 分子名称: | 5'-d(CGCG(TCY)ATTCGCG)-3', SPERMINE, ZINC ION | | 著者 | Pallan, P.S, Ittig, D, Heroux, A, Wawrzak, Z, Leumann, C.J, Egli, M. | | 登録日 | 2007-09-27 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles.
Chem.Commun.(Camb.), 2008, 2008
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8SKQ
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7UCR
 | | Joint X-ray/neutron structure of the Sarcin-Ricin loop RNA | | 分子名称: | SULFATE ION, Sarcin-Ricin loop RNA | | 著者 | Harp, J.M, Egli, M.E, Pallan, P.S, Coates, L. | | 登録日 | 2022-03-17 | | 公開日 | 2022-07-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | NEUTRON DIFFRACTION (1 Å), X-RAY DIFFRACTION | | 主引用文献 | Cryo neutron crystallography demonstrates influence of RNA 2'-OH orientation on conformation, sugar pucker and water structure.
Nucleic Acids Res., 50, 2022
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6VEM
 | | Structure of RNA octamer | | 分子名称: | COBALT HEXAMMINE(III), Modified Octamer RNA | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2020-01-02 | | 公開日 | 2020-11-18 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Synthesis, chirality-dependent conformational and biological properties of siRNAs containing 5'-(R)- and 5'-(S)-C-methyl-guanosine.
Nucleic Acids Res., 48, 2020
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1HRU
 | | THE STRUCTURE OF THE YRDC GENE PRODUCT FROM E.COLI | | 分子名称: | PHOSPHATE ION, YRDC GENE PRODUCT | | 著者 | Teplova, M, Tereshko, V, Sanishvili, R, Joachimiak, A, Bushueva, T, Anderson, W.F, Egli, M, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2000-12-21 | | 公開日 | 2001-01-31 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding.
Protein Sci., 9, 2000
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1EX2
 | | CRYSTAL STRUCTURE OF BACILLUS SUBTILIS MAF PROTEIN | | 分子名称: | PHOSPHATE ION, PROTEIN MAF, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | 著者 | Minasov, G, Teplova, M, Stewart, G.C, Koonin, E.V, Anderson, W.F, Egli, M, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2000-04-28 | | 公開日 | 2000-06-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Functional implications from crystal structures of the conserved Bacillus subtilis protein Maf with and without dUTP.
Proc.Natl.Acad.Sci.USA, 97, 2000
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8SV4
 | | 7-Deazapurines and 5-Halogenpyrimidine DNA duplex | | 分子名称: | 1,2-ETHANEDIOL, 2-[2-(2-ethoxyethoxy)ethoxy]ethanol, ACETATE ION, ... | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2023-05-15 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Conformational Morphing by a DNA Analogue Featuring 7-Deazapurines and 5-Halogenpyrimidines and the Origins of Adenine-Tract Geometry.
Biochemistry, 62, 2023
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8SV3
 | | 7-Deazapurines and 5-Halogenpyrimidine DNA duplex | | 分子名称: | GLYCEROL, MAGNESIUM ION, Modified DNA, ... | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2023-05-15 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Conformational Morphing by a DNA Analogue Featuring 7-Deazapurines and 5-Halogenpyrimidines and the Origins of Adenine-Tract Geometry.
Biochemistry, 62, 2023
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7U38
 | | Pixantrone tethered DNA duplex | | 分子名称: | 1,2-ETHANEDIOL, Pixantrone AP conjugate-modified DNA | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2022-02-26 | | 公開日 | 2023-03-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Structural Characterization of a Covalent Conjugate between Pixantrone and an Abasic Site in DNA
To Be Published
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1G2J
 | | RNA OCTAMER R(CCCP*GGGG) CONTAINING PHENYL RIBONUCLEOTIDE | | 分子名称: | 5'-R(*CP*CP*CP*(PYY)P*GP*GP*GP*G)-3', CALCIUM ION | | 著者 | Minasov, G, Matulic-Adamic, J, Wilds, C.J, Haeberli, P, Usman, N, Beigelman, L, Egli, M. | | 登録日 | 2000-10-20 | | 公開日 | 2000-12-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Crystal structure of an RNA duplex containing phenyl-ribonucleotides, hydrophobic isosteres of the natural pyrimidines.
RNA, 6, 2000
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8CTY
 | | 12-mer DNA structure of ExBIM bound to RNase-H | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2022-05-16 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Conformation and Pairing Properties of an O 6 -Methyl-2'-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA.
Chem.Res.Toxicol., 35, 2022
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8CU0
 | | 12-mer DNA structure of ExBIM bound to RNaseH -modified DDD | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*(OWR)P*CP*CP*G)-3'), GLYCEROL, ... | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2022-05-16 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Conformation and Pairing Properties of an O 6 -Methyl-2'-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA.
Chem.Res.Toxicol., 35, 2022
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8CTZ
 | | 12-mer DNA structure of ExBIM & O6Me-G bound to RNase-H | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*CP*GP*CP*(6OG)P*AP*AP*TP*TP*(OWR)P*GP*CP*G)-3'), ... | | 著者 | Pallan, P.S, Egli, M. | | 登録日 | 2022-05-16 | | 公開日 | 2022-08-31 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Conformation and Pairing Properties of an O 6 -Methyl-2'-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA.
Chem.Res.Toxicol., 35, 2022
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7JY2
 | | Z-DNA joint X-ray/Neutron | | 分子名称: | Chains: A,B | | 著者 | Harp, J.M, Coates, L, Egli, M. | | 登録日 | 2020-08-28 | | 公開日 | 2021-04-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | NEUTRON DIFFRACTION (1.5 Å), X-RAY DIFFRACTION | | 主引用文献 | Water structure around a left-handed Z-DNA fragment analyzed by cryo neutron crystallography.
Nucleic Acids Res., 49, 2021
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7JJE
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7JJF
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7JJD
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7LO9
 | | RNA dodecamer containing a GNA A residue | | 分子名称: | Chains: A,B,C,D | | 著者 | Harp, J.M, Wawrzak, Z, Egli, M. | | 登録日 | 2021-02-09 | | 公開日 | 2021-12-22 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Overcoming GNA/RNA base-pairing limitations using isonucleotides improves the pharmacodynamic activity of ESC+ GalNAc-siRNAs.
Nucleic Acids Res., 49, 2021
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9BF2
 | | MID domain of Ago2 bound to UMP | | 分子名称: | Protein argonaute-2, URIDINE-5'-MONOPHOSPHATE | | 著者 | Harp, J.M, Egli, M. | | 登録日 | 2024-04-16 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth.
Curr Protoc, 4, 2024
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9BF0
 | | MID domain of human Argo2 bound to UTP | | 分子名称: | Protein argonaute-2, URIDINE 5'-TRIPHOSPHATE | | 著者 | Harp, J.M, Egli, M. | | 登録日 | 2024-04-16 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth.
Curr Protoc, 4, 2024
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9BEZ
 | | MID domain of human Argo2 bound to RNA | | 分子名称: | Protein argonaute-2, [(3~{S},4~{R},5~{R})-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-4-oxidanyl-oxolan-3-yl] [oxidanyl(phosphonooxy)phosphoryl] hydrogen phosphate | | 著者 | Harp, J.M, Egli, M. | | 登録日 | 2024-04-16 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth.
Curr Protoc, 4, 2024
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8UK4
 | | Crystal structure of human polymerase eta with incoming dTMPnPP nucleotide opposite urea lesion | | 分子名称: | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(UD8)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... | | 著者 | Tomar, R, Egli, M, Stone, M.P. | | 登録日 | 2023-10-12 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | | 主引用文献 | Replication Bypass of the N -(2-Deoxy-d-erythro-pentofuranosyl)-urea DNA Lesion by Human DNA Polymerase eta.
Biochemistry, 63, 2024
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8UJX
 | | Crystal structure of human polymerase eta with incoming dGMPnPP nucleotide opposite urea lesion | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(UD8)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... | | 著者 | Tomar, R, Egli, M, Stone, M.P. | | 登録日 | 2023-10-11 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Replication Bypass of the N -(2-Deoxy-d-erythro-pentofuranosyl)-urea DNA Lesion by Human DNA Polymerase eta.
Biochemistry, 63, 2024
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8UJV
 | | Crystal structure of human polymerase eta with incoming dCMPnPP nucleotide opposite urea lesion | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(UD8)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... | | 著者 | Tomar, R, Egli, M, Stone, M.P. | | 登録日 | 2023-10-11 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Replication Bypass of the N -(2-Deoxy-d-erythro-pentofuranosyl)-urea DNA Lesion by Human DNA Polymerase eta.
Biochemistry, 63, 2024
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