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PDB: 44 results

4ONM
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BU of 4onm by Molmil
Crystal structure of human Mms2/Ubc13 - NSC697923
Descriptor: 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ...
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-28
Release date:2015-05-06
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4OFB
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BU of 4ofb by Molmil
Crystal structure of human BRCA1 BRCT in complex with nonphosphopeptide inhibitor
Descriptor: Breast cancer type 1 susceptibility protein, nonphosphopeptide inhibitor
Authors:Sun, L, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-14
Release date:2015-04-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain.
Acs Chem.Biol., 10, 2015
4ONN
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BU of 4onn by Molmil
Crystal structure of human Mms2/Ubc13 - BAY 11-7082
Descriptor: 3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ...
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-28
Release date:2015-05-06
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4ONL
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BU of 4onl by Molmil
Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P
Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-01-28
Release date:2015-05-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4ORH
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BU of 4orh by Molmil
Crystal structure of RNF8 bound to the UBC13/MMS2 heterodimer
Descriptor: E3 ubiquitin-protein ligase RNF8, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.M.
Deposit date:2014-02-11
Release date:2014-02-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.802 Å)
Cite:Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
J.Biol.Chem., 287, 2012
4QPQ
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BU of 4qpq by Molmil
Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM
Descriptor: Relaxosome protein TraM, sbmA DNA1, sbmA DNA2
Authors:Peng, Y, Lu, J, Wong, J, Edwards, R.A, Frost, L.S, Glover, J.N.M.
Deposit date:2014-06-24
Release date:2014-09-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.106 Å)
Cite:Mechanistic Basis of Plasmid-Specific DNA Binding of the F Plasmid Regulatory Protein, TraM.
J.Mol.Biol., 426, 2014
4QPO
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BU of 4qpo by Molmil
Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM
Descriptor: PHOSPHATE ION, Relaxosome protein TraM
Authors:Peng, Y, Lu, J, Wong, J, Edwards, R.A, Frost, L.S, Glover, J.N.M.
Deposit date:2014-06-24
Release date:2014-09-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Mechanistic Basis of Plasmid-Specific DNA Binding of the F Plasmid Regulatory Protein, TraM.
J.Mol.Biol., 426, 2014
2R1Z
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BU of 2r1z by Molmil
Crystal Structure of the BARD1 BRCT Repeat
Descriptor: BRCA1-associated RING domain protein 1, GLYCEROL
Authors:Lee, M.S, Edwards, R.A, Williams, R.S, Glover, M.J.N.
Deposit date:2007-08-23
Release date:2007-09-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the BARD1 BRCT Repeat
To be Published
3K16
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BU of 3k16 by Molmil
Crystal Structure of BRCA1 BRCT D1840T in complex with a minimal recognition tetrapeptide with a free carboxy C-terminus
Descriptor: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.
Deposit date:2009-09-25
Release date:2010-03-02
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K05
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BU of 3k05 by Molmil
The crystal structure of MDC1 BRCT T2067D in complex with a minimal recognition tetrapeptide with an amidated C-terminus
Descriptor: GLYCEROL, Mediator of DNA damage checkpoint protein 1, phospho peptide
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.
Deposit date:2009-09-24
Release date:2010-03-02
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K0H
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BU of 3k0h by Molmil
The crystal structure of BRCA1 BRCT in complex with a minimal recognition tetrapeptide with an amidated C-terminus
Descriptor: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.
Deposit date:2009-09-24
Release date:2010-03-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K15
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BU of 3k15 by Molmil
Crystal Structure of BRCA1 BRCT D1840T in complex with a minimal recognition tetrapeptide with an amidated C-terminus
Descriptor: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.
Deposit date:2009-09-25
Release date:2010-03-02
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3K0K
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BU of 3k0k by Molmil
Crystal Structure of BRCA1 BRCT in complex with a minimal recognition tetrapeptide with a free carboxy C-terminus.
Descriptor: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
Authors:Campbell, S.J, Edwards, R.A, Glover, J.N.
Deposit date:2009-09-24
Release date:2010-03-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010
3D8A
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BU of 3d8a by Molmil
Co-crystal structure of TraM-TraD complex.
Descriptor: Protein traD, Relaxosome protein TraM
Authors:Glover, J.N.M, Lu, J, Wong, J.J, Edwards, R.A.
Deposit date:2008-05-22
Release date:2008-09-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis of specific TraD-TraM recognition during F plasmid-mediated bacterial conjugation.
Mol.Microbiol., 70, 2008
3QZC
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BU of 3qzc by Molmil
Structure of the periplasmic stress response protein CpxP
Descriptor: Periplasmic protein CpxP, ZINC ION
Authors:Thede, G.L, Edwards, R.A, Glover, J.N.M.
Deposit date:2011-03-04
Release date:2011-03-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of the Periplasmic Stress Response Protein CpxP.
J.Bacteriol., 193, 2011
3OMY
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BU of 3omy by Molmil
Crystal structure of the pED208 TraM N-terminal domain
Descriptor: GLYCEROL, MAGNESIUM ION, Protein traM
Authors:Wong, J.J.W, Lu, J, Edwards, R.A, Frost, L.S, Mark Glover, J.N.
Deposit date:2010-08-27
Release date:2011-05-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural basis of cooperative DNA recognition by the plasmid conjugation factor, TraM.
Nucleic Acids Res., 39, 2011
3ON0
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BU of 3on0 by Molmil
Crystal structure of the pED208 TraM-sbmA complex
Descriptor: Protein traM, sbmA
Authors:Wong, J.J.W, Lu, J, Edwards, R.A, Frost, L.S, Mark Glover, J.N.
Deposit date:2010-08-27
Release date:2011-05-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.874 Å)
Cite:Structural basis of cooperative DNA recognition by the plasmid conjugation factor, TraM.
Nucleic Acids Res., 39, 2011
5U6K
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BU of 5u6k by Molmil
Crystal structure of TopBP1 BRCT4/5 in complex with a BLM phosphopeptide
Descriptor: Bloom Sydrome recQ helicase like protein (BLM), DNA topoisomerase 2-binding protein 1
Authors:Glover, J.N.M, Sun, L, Edwards, R.A.
Deposit date:2016-12-08
Release date:2017-10-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insight into BLM Recognition by TopBP1.
Structure, 25, 2017
4NRG
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BU of 4nrg by Molmil
Crystal Structure of a human Mms2/Ubc13 D118G mutant
Descriptor: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
Authors:Hodge, C.D, Edwards, R.A, Glover, J.N.M.
Deposit date:2013-11-26
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes.
J.Am.Chem.Soc., 136, 2014
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