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PDB: 44 件
1EN5
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CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Y34F MUTANT
分子名称: MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE
著者Edwards, R.A, Whittaker, M.M, Baker, E.N, Whittaker, J.W, Jameson, G.B.
登録日2000-03-20
公開日2001-06-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Outer sphere mutations perturb metal reactivity in manganese superoxide dismutase.
Biochemistry, 40, 2001
1EN4
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CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Q146H MUTANT
分子名称: MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE
著者Edwards, R.A, Whittaker, M.M, Baker, E.N, Whittaker, J.W, Jameson, G.B.
登録日2000-03-20
公開日2001-06-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Outer sphere mutations perturb metal reactivity in manganese superoxide dismutase.
Biochemistry, 40, 2001
1EN6
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BU of 1en6 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE Q146L MUTANT
分子名称: MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE
著者Edwards, R.A, Whittaker, M.M, Baker, E.N, Whittaker, J.W, Jameson, G.B.
登録日2000-03-20
公開日2001-06-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Outer sphere mutations perturb metal reactivity in manganese superoxide dismutase.
Biochemistry, 40, 2001
1VEW
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BU of 1vew by Molmil
MANGANESE SUPEROXIDE DISMUTASE FROM ESCHERICHIA COLI
分子名称: HYDROXIDE ION, MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE
著者Edwards, R.A, Baker, H.M, Whittaker, M.M, Whittaker, J.W, Jameson, G.B, Baker, E.N.
登録日1998-01-20
公開日1998-05-27
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Escherichia coli manganese superoxide dismutase at 2.1-angstrom resolution.
J.Biol.Inorg.Chem., 3, 1998
1I08
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BU of 1i08 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE H30A MUTANT OF MANGANESE SUPEROXIDE DISMUTASE FROM E. COLI
分子名称: MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE
著者Edwards, R.A, Whittaker, M.M, Whittaker, J.W, Baker, E.N, Jameson, G.B.
登録日2001-01-29
公開日2001-02-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Removing a hydrogen bond in the dimer interface of Escherichia coli manganese superoxide dismutase alters structure and reactivity.
Biochemistry, 40, 2001
1I0H
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BU of 1i0h by Molmil
CRYSTAL STRUCTURE OF THE E. COLI MANGANESE SUPEROXIDE DISMUTASE MUTANT Y174F AT 1.35 ANGSTROMS RESOLUTION.
分子名称: MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE Y174F MUTANT
著者Edwards, R.A, Whittaker, M.M, Whittaker, J.W, Baker, E.N, Jameson, G.B.
登録日2001-01-29
公開日2001-02-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Removing a hydrogen bond in the dimer interface of Escherichia coli manganese superoxide dismutase alters structure and reactivity.
Biochemistry, 40, 2001
1MMM
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DISTINCT METAL ENVIRONMENT IN IRON-SUBSTITUTED MANGANESE SUPEROXIDE DISMUTASE PROVIDES A STRUCTURAL BASIS OF METAL SPECIFICITY
分子名称: FE (III) ION, HYDROXIDE ION, PROTEIN (IRON-SUBSTITUTED MANGANESE SUPEROXIDE DISMUTASE)
著者Edwards, R.A, Whittaker, M.M, Whittaker, J.W, Jameson, G.B, Baker, E.N.
登録日1998-08-26
公開日1998-09-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Distinct Metal Environment in Fe-Substituted Manganese Superoxide Dismutase Provides a Structural Basis of Metal Specificity
J.Am.Chem.Soc., 120, 1998
8D34
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Crystal Structure of SARS CoV-2 NSP15 Endroribonuclease H250A
分子名称: Uridylate-specific endoribonuclease nsp15
著者Farraj, R.A, Edwards, R.A, Glover, J.N.M.
登録日2022-05-31
公開日2023-06-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Crystal Structure of SARS CoV-2 NSP15 Endroribonuclease H250A
To Be Published
8UK7
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Periplasmic domain of Escherichia coli CpxA
分子名称: Sensor histidine kinase CpxA
著者Glover, M.J.N, Murray, C.R.A, Edwards, R.A, Thede, G.L.
登録日2023-10-12
公開日2023-10-25
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The sensor of the bacterial histidine kinase CpxA is a novel dimer of extracytoplasmic Per-ARNT-Sim domains.
J.Biol.Chem., 300, 2024
9BIV
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Crystal Structure of Ubc13 with a New Active Site Loop Conformation
分子名称: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
著者Farraj, R.A, Edwards, R.A, Glover, J.N.M.
登録日2024-04-24
公開日2024-05-08
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Crystal Structure of Ubc13 with a New Active Site Loop Conformation
To Be Published
2ADO
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BU of 2ado by Molmil
Crystal Structure Of The Brct Repeat Region From The Mediator of DNA damage checkpoint protein 1, MDC1
分子名称: Mediator of DNA damage checkpoint protein 1
著者Lee, M.S, Edwards, R.A, Thede, G.L, Glover, J.N.
登録日2005-07-20
公開日2005-08-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure of the BRCT Repeat Domain of MDC1 and Its Specificity for the Free COOH-terminal End of the {gamma}-H2AX Histone Tail.
J.Biol.Chem., 280, 2005
1IX9
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BU of 1ix9 by Molmil
Crystal Structure of the E. coli Manganase(III) superoxide dismutase mutant Y174F at 0.90 angstroms resolution.
分子名称: MANGANESE (II) ION, Superoxide Dismutase
著者Anderson, B.F, Edwards, R.A, Whittaker, M.M, Whittaker, J.W, Baker, E.N, Jameson, G.B.
登録日2002-06-17
公開日2002-12-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献Structures at 0.90 A resolution of the oxidised and reduced forms of the Y174F mutant of the manganese superoxide dismutase from Escherichia coli
To be Published
1IXB
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CRYSTAL STRUCTURE OF THE E. COLI MANGANESE(II) SUPEROXIDE DISMUTASE MUTANT Y174F AT 0.90 ANGSTROMS RESOLUTION.
分子名称: MANGANESE ION, 1 HYDROXYL COORDINATED, SUPEROXIDE DISMUTASE
著者Anderson, B.F, Edwards, R.A, Whittaker, M.M, Whittaker, J.W, Baker, E.N, Jameson, G.B.
登録日2002-06-18
公開日2002-12-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献Structures at 0.90 A resolution of the oxidised and reduced forms of the Y174F mutant of the manganese superoxide dismutase from Escherichia coli
To be Published
4WHV
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BU of 4whv by Molmil
E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B
分子名称: E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ...
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2014-09-23
公開日2015-09-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (8.3 Å)
主引用文献RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
J.Biol.Chem., 291, 2016
4QPQ
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BU of 4qpq by Molmil
Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM
分子名称: Relaxosome protein TraM, sbmA DNA1, sbmA DNA2
著者Peng, Y, Lu, J, Wong, J, Edwards, R.A, Frost, L.S, Glover, J.N.M.
登録日2014-06-24
公開日2014-09-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.106 Å)
主引用文献Mechanistic Basis of Plasmid-Specific DNA Binding of the F Plasmid Regulatory Protein, TraM.
J.Mol.Biol., 426, 2014
4ONM
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BU of 4onm by Molmil
Crystal structure of human Mms2/Ubc13 - NSC697923
分子名称: 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ...
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2014-01-28
公開日2015-05-06
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4ONN
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Crystal structure of human Mms2/Ubc13 - BAY 11-7082
分子名称: 3-[(4-methylphenyl)sulfonyl]prop-2-enenitrile, GLYCEROL, Ubiquitin-conjugating enzyme E2 N, ...
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2014-01-28
公開日2015-05-06
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4OFB
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Crystal structure of human BRCA1 BRCT in complex with nonphosphopeptide inhibitor
分子名称: Breast cancer type 1 susceptibility protein, nonphosphopeptide inhibitor
著者Sun, L, Edwards, R.A, Glover, J.N.M.
登録日2014-01-14
公開日2015-04-15
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain.
Acs Chem.Biol., 10, 2015
4ONL
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Crystal structure of human Mms2/Ubc13_D81N, R85S, A122V, N123P
分子名称: Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2014-01-28
公開日2015-05-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.
Acs Chem.Biol., 10, 2015
4ORH
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BU of 4orh by Molmil
Crystal structure of RNF8 bound to the UBC13/MMS2 heterodimer
分子名称: E3 ubiquitin-protein ligase RNF8, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2, ...
著者Campbell, S.J, Edwards, R.A, Glover, J.N.M.
登録日2014-02-11
公開日2014-02-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.802 Å)
主引用文献Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
J.Biol.Chem., 287, 2012
4QPO
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BU of 4qpo by Molmil
Mechanistic basis of plasmid-specific DNA binding of the F plasmid regulatory protein, TraM
分子名称: PHOSPHATE ION, Relaxosome protein TraM
著者Peng, Y, Lu, J, Wong, J, Edwards, R.A, Frost, L.S, Glover, J.N.M.
登録日2014-06-24
公開日2014-09-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Mechanistic Basis of Plasmid-Specific DNA Binding of the F Plasmid Regulatory Protein, TraM.
J.Mol.Biol., 426, 2014
1J74
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Crystal Structure of Mms2
分子名称: MMS2
著者Moraes, T.F, Edwards, R.A, McKenna, S, Pastushok, L, Xiao, W, Glover, J.N.M, Ellison, M.J.
登録日2001-05-15
公開日2001-08-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13.
Nat.Struct.Biol., 8, 2001
1J7D
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BU of 1j7d by Molmil
Crystal Structure of hMms2-hUbc13
分子名称: MMS2, UBIQUITIN-CONJUGATING ENZYME E2-17 KDA
著者Moraes, T.F, Edwards, R.A, McKenna, S, Pashushok, L, Xiao, W, Glover, J.N.M, Ellison, M.J.
登録日2001-05-16
公開日2001-08-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13.
Nat.Struct.Biol., 8, 2001
5U6K
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Crystal structure of TopBP1 BRCT4/5 in complex with a BLM phosphopeptide
分子名称: Bloom Sydrome recQ helicase like protein (BLM), DNA topoisomerase 2-binding protein 1
著者Glover, J.N.M, Sun, L, Edwards, R.A.
登録日2016-12-08
公開日2017-10-04
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Insight into BLM Recognition by TopBP1.
Structure, 25, 2017
3K16
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Crystal Structure of BRCA1 BRCT D1840T in complex with a minimal recognition tetrapeptide with a free carboxy C-terminus
分子名称: Breast cancer type 1 susceptibility protein, CHLORIDE ION, NICKEL (II) ION, ...
著者Campbell, S.J, Edwards, R.A, Glover, J.N.
登録日2009-09-25
公開日2010-03-02
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Structure, 18, 2010

 

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