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PDB: 357 件

1Z39
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Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with 2'-deoxyinosine
分子名称: 2'-DEOXYINOSINE, purine nucleoside phosphorylase
著者Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E.
登録日2005-03-10
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
J.Biol.Chem., 280, 2005
1Z38
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Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with inosine
分子名称: INOSINE, purine nucleoside phosphorylase
著者Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E.
登録日2005-03-10
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
J.Biol.Chem., 280, 2005
1Z35
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Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with 2-fluoroadenosine
分子名称: 2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, purine nucleoside phosphorylase
著者Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E.
登録日2005-03-10
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
J.Biol.Chem., 280, 2005
1YAD
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Structure of TenI from Bacillus subtilis
分子名称: Regulatory protein tenI, SULFATE ION, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM
著者Toms, A.V, Haas, A.L, Park, J.-H, Begley, T.P, Ealick, S.E.
登録日2004-12-17
公開日2005-02-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II.
Biochemistry, 44, 2005
1EKK
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CRYSTAL STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE IN THE R3 FORM WITH HYDROXYETHYLTHIAZOLE
分子名称: 2-(4-METHYL-THIAZOL-5-YL)-ETHANOL, HYDROXYETHYLTHIAZOLE KINASE, SULFUR DIOXIDE
著者Campobasso, N, Mathews, I.I, Begley, T.P, Ealick, S.E.
登録日2000-03-09
公開日2000-08-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution.
Biochemistry, 39, 2000
3QH2
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Crystal structure of TenI from Bacillus subtilis complexed with product cThz-P
分子名称: 4-methyl-5-[2-(phosphonooxy)ethyl]-1,3-thiazole-2-carboxylic acid, Regulatory protein tenI, SULFATE ION
著者Han, Y, Zhang, Y, Hazra, A, Chatterjee, A, Lai, R, Begley, T.P, Ealick, S.E.
登録日2011-01-25
公開日2011-05-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.231 Å)
主引用文献A Missing Enzyme in Thiamin Thiazole Biosynthesis: Identification of TenI as a Thiazole Tautomerase.
J.Am.Chem.Soc., 133, 2011
1YFW
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Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans complexed with 4-chloro-3-hydroxyanthranilic acid and O2
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate-3,4-dioxygenase, 4-CHLORO-3-HYDROXYANTHRANILIC ACID, ...
著者Zhang, Y, Colabroy, K.L, Begley, T.P, Ealick, S.E.
登録日2005-01-04
公開日2005-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis.
Biochemistry, 44, 2005
1YAK
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Complex of Bacillus subtilis TenA with 4-amino-2-methyl-5-hydroxymethylpyrimidine
分子名称: 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, Transcriptional activator tenA
著者Toms, A.V, Haas, A.L, Park, J.-H, Begley, T.P, Ealick, S.E.
登録日2004-12-17
公開日2005-02-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II.
Biochemistry, 44, 2005
3PKW
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Crystal Structure of Toxoflavin Lyase (TflA) bound to Mn(II)
分子名称: MANGANESE (II) ION, Toxoflavin lyase (TflA)
著者Fenwick, M.K, Philmus, B, Begley, T.P, Ealick, S.E.
登録日2010-11-12
公開日2011-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Toxoflavin lyase requires a novel 1-his-2-carboxylate facial triad .
Biochemistry, 50, 2011
1Z34
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Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with 2-fluoro-2'-deoxyadenosine
分子名称: 5-(6-AMINO-2-FLUORO-PURIN-9-YL)-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-OL, purine nucleoside phosphorylase
著者Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E.
登録日2005-03-10
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
J.Biol.Chem., 280, 2005
1Y1Q
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Crystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium in Complex with Uridine-5p-monophosphate and Sulfate Ion at 2.35A Resolution
分子名称: SULFATE ION, URIDINE-5'-MONOPHOSPHATE, Uridine phosphorylase
著者Gabdoulkhakov, A.G, Dontsova, M.V, Kachalova, G.S, Betzel, C, Ealick, S.E, Mikhailov, A.M.
登録日2004-11-19
公開日2005-11-22
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structures of Salmonella Typhimurium Uridine Phosphorylase in Native and Three Complexes Forms - with Uridine, Uracil and Sulfate.
To be Published
1Y1S
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Crystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium in Complex with Uracil and Sulfate Ion at 2.55A Resolution
分子名称: SULFATE ION, URACIL, Uridine phosphorylase
著者Gabdoulkhakov, A.G, Dontsova, M.V, Kachalova, G.S, Betzel, C, Ealick, S.E, Mikhailov, A.M.
登録日2004-11-19
公開日2005-11-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal Structures of Salmonella Typhimurium Uridine Phosphorylase in Native and Three Complexes Forms - with Uridine, Uracil and Sulfate.
To be Published
1Z37
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Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with adenosine
分子名称: ADENOSINE, purine nucleoside phosphorylase
著者Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E.
登録日2005-03-10
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
J.Biol.Chem., 280, 2005
3RW9
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Crystal Structure of human Spermidine Synthase in Complex with decarboxylated S-adenosylhomocysteine
分子名称: 5'-S-(3-aminopropyl)-5'-thioadenosine, Spermidine synthase
著者Seckute, J, McCloskey, D.E, Thomas, H.J, Secrist III, J.A, Pegg, A.E, Ealick, S.E.
登録日2011-05-08
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding and inhibition of human spermidine synthase by decarboxylated S-adenosylhomocysteine.
Protein Sci., 20, 2011
3RI6
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A Novel Mechanism of Sulfur Transfer Catalyzed by O-Acetylhomoserine Sulfhydrylase in Methionine Biosynthetic Pathway of Wolinella succinogenes
分子名称: O-ACETYLHOMOSERINE SULFHYDRYLASE
著者Tran, T.H, Krishnamoorthy, K, Begley, T.P, Ealick, S.E.
登録日2011-04-13
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A novel mechanism of sulfur transfer catalyzed by O-acetylhomoserine sulfhydrylase in the methionine-biosynthetic pathway of Wolinella succinogenes.
Acta Crystallogr.,Sect.D, 67, 2011
1Y1R
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Crystal Structure of the Uridine Phosphorylase from Salmonella Typhimurium in Complex with Inhibitor and Phosphate Ion at 2.11A Resolution
分子名称: 2,2'-Anhydro-(1-beta-D-ribofuranosyl)uracil, PHOSPHATE ION, Uridine phosphorylase
著者Dontsova, M.V, Gabdoulkhakov, A.G, Kachalova, G.S, Betzel, C, Ealick, S.E, Mikhailov, A.M.
登録日2004-11-19
公開日2005-11-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Crystal Structures of Salmonella Typhimurium Uridine Phosphorylase in Complex with Inhibitor and Phosphate.
To be Published
1YFY
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Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans complexed with 3-hydroxyanthranilic acid
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-HYDROXYANTHRANILIC ACID, 3-hydroxyanthranilate-3,4-dioxygenase, ...
著者Zhang, Y, Colabroy, K.L, Begley, T.P, Ealick, S.E.
登録日2005-01-04
公開日2005-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis.
Biochemistry, 44, 2005
1YAF
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Structure of TenA from Bacillus subtilis
分子名称: Transcriptional activator tenA
著者Toms, A.V, Haas, A.L, Park, J.-H, Begley, T.P, Ealick, S.E.
登録日2004-12-17
公開日2005-02-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II.
Biochemistry, 44, 2005
1YMW
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The study of reductive unfolding pathways of RNase A (Y92G mutant)
分子名称: Ribonuclease pancreatic
著者Xu, G, Narayan, M, Kurinov, I, Ripoll, D.R, Welker, E, Khalili, M, Ealick, S.E, Scheraga, H.A.
登録日2005-01-21
公開日2006-01-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A localized specific interaction alters the unfolding pathways of structural homologues.
J.Am.Chem.Soc., 128, 2006
1Z36
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Crystal structure of Trichomonas vaginalis purine nucleoside phosphorylase complexed with formycin A
分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, purine nucleoside phosphorylase
著者Zhang, Y, Wang, W.H, Wu, S.W, Wang, C.C, Ealick, S.E.
登録日2005-03-10
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
J.Biol.Chem., 280, 2005
3O7K
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Crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase from Klebsiella pneumoniae
分子名称: OHCU decarboxylase
著者French, J.B, Ealick, S.E.
登録日2010-07-30
公開日2010-09-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural and Mechanistic Studies on Klebsiella pneumoniae 2-Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline Decarboxylase.
J.Biol.Chem., 285, 2010
3O94
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High resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into catalytic mechanism and inhibition by aldehydes
分子名称: NICOTINAMIDE, ZINC ION, nicotinamidase
著者French, J.B, Cen, Y, Sauve, A.A, Ealick, S.E.
登録日2010-08-03
公開日2011-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献High-resolution crystal structures of Streptococcus pneumoniae nicotinamidase with trapped intermediates provide insights into the catalytic mechanism and inhibition by aldehydes .
Biochemistry, 49, 2010
1CSG
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Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor
分子名称: Granulocyte-macrophage colony-stimulating factor
著者Walter, M.R, Cook, W.J, Ealick, S.E.
登録日1992-11-23
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor.
J.Mol.Biol., 224, 1992
3QPB
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Crystal Structure of Streptococcus Pyogenes Uridine Phosphorylase Reveals a Subclass of the NP-I Superfamily
分子名称: 1-O-phosphono-alpha-D-ribofuranose, URACIL, Uridine phosphorylase
著者Tran, T.H, Christoffersen, S, Parker, W.B, Piskur, J, Serra, I, Terreni, M, Ealick, S.E.
登録日2011-02-11
公開日2011-08-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献The Crystal Structure of Streptococcus pyogenes Uridine Phosphorylase Reveals a Distinct Subfamily of Nucleoside Phosphorylases.
Biochemistry, 50, 2011
2ABS
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Crystal structure of T. gondii adenosine kinase complexed with AMP-PCP
分子名称: CHLORIDE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SODIUM ION, ...
著者Zhang, Y, el Kouni, M.H, Ealick, S.E.
登録日2005-07-16
公開日2006-01-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Structure of Toxoplasma gondii adenosine kinase in complex with an ATP analog at 1.1 angstroms resolution.
Acta Crystallogr.,Sect.D, 62, 2006

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