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PDB: 357 件
1QCZ
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CRYSTAL STRUCTURE OF E. COLI PURE, AN UNUSUAL MUTASE THAT CATALYZES THE CONVERSION OF N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE (N5-CAIR) TO 4-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE (CAIR) IN THE PURINE BIOSYNTHETIC PATHWAY
分子名称: N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE MUTASE
著者Ealick, S.E, Mathews, I.I.
登録日1999-05-10
公開日1999-11-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of Escherichia coli PurE, an unusual mutase in the purine biosynthetic pathway.
Structure Fold.Des., 7, 1999
5HFT
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Crystal structure of HpxW
分子名称: Gamma-glutamyltranspeptidase
著者Ealick, S.E, Hicks, K.A.
登録日2016-01-07
公開日2016-06-29
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.646 Å)
主引用文献Biochemical and structural characterization of Klebsiella pneumoniae oxamate amidohydrolase in the uric acid degradation pathway.
Acta Crystallogr D Struct Biol, 72, 2016
1ULB
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BU of 1ulb by Molmil
APPLICATION OF CRYSTALLOGRAPHIC AND MODELING METHODS IN THE DESIGN OF PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS
分子名称: GUANINE, PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION
著者Ealick, S.E, Rule, S.A, Carter, D.C, Greenhough, T.J, Babu, Y.S, Cook, W.J, Habash, J, Helliwell, J.R, Stoeckler, J.D, Parksjunior, R.E, Chen, S.-F, Bugg, C.E.
登録日1991-11-05
公開日1993-01-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors.
Proc.Natl.Acad.Sci.USA, 88, 1991
1ULA
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BU of 1ula by Molmil
APPLICATION OF CRYSTALLOGRAPHIC AND MODELING METHODS IN THE DESIGN OF PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS
分子名称: PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION
著者Ealick, S.E, Rule, S.A, Carter, D.C, Greenhough, T.J, Babu, Y.S, Cook, W.J, Habash, J, Helliwell, J.R, Stoeckler, J.D, Parksjunior, R.E, Chen, S.-F, Bugg, C.E.
登録日1991-11-05
公開日1993-01-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors.
Proc.Natl.Acad.Sci.USA, 88, 1991
1HIG
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BU of 1hig by Molmil
THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT HUMAN INTERFERON-GAMMA.
分子名称: INTERFERON-GAMMA
著者Ealick, S.E, Cook, W.J, Vijay-Kumar, S, Carson, M, Nagabhushan, T.L, Trotta, P.P, Bugg, C.E.
登録日1991-10-03
公開日1992-04-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Three-dimensional structure of recombinant human interferon-gamma.
Science, 252, 1991
1ZUD
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BU of 1zud by Molmil
Structure of ThiS-ThiF protein complex
分子名称: Adenylyltransferase thiF, CALCIUM ION, SODIUM ION, ...
著者Ealick, S.E, Lehmann, C.
登録日2005-05-30
公開日2006-01-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structure of the Escherichia coli ThiS-ThiF Complex, a Key Component of the Sulfur Transfer System in Thiamin Biosynthesis.
Biochemistry, 45, 2006
1OV6
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BU of 1ov6 by Molmil
M64V PNP + ALLO
分子名称: 9-(6-DEOXY-BETA-D-ALLOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, P.W, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-25
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OUM
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M64V PNP +Talo
分子名称: 9-(6-DEOXY-ALPHA-L-TALOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-24
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OU4
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Native PNP +Talo
分子名称: 6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-24
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OVG
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M64V PNP +MePdr
分子名称: 9-(2-DEOXY-BETA-D-RIBOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, P.W, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-26
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OTY
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Native PNP +ALLO
分子名称: 6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-23
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OTX
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Purine Nucleoside Phosphorylase M64V mutant
分子名称: PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
登録日2003-03-23
公開日2004-02-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1T3T
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Structure of Formylglycinamide synthetase
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoribosylformylglycinamidine synthase, ...
著者Ealick, S.E, Anand, R, Hoskin, A.A, Stubbe, J.
登録日2004-04-27
公開日2004-09-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Domain Organization of Salmonella typhimurium Formylglycinamide Ribonucleotide Amidotransferase Revealed by X-ray crystallography
Biochemistry, 43, 2004
2QJI
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M. jannaschii ADH synthase complexed with dihydroxyacetone phosphate and glycerol
分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, GLYCEROL, Putative aldolase MJ0400
著者Ealick, S.E, Morar, M.
登録日2007-07-07
公開日2007-10-30
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid synthase, a catalyst in the archaeal pathway for the biosynthesis of aromatic amino acids.
Biochemistry, 46, 2007
2QQD
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N47A mutant of Pyruvoyl-dependent Arginine Decarboxylase from Methanococcus jannashii
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, AGMATINE, PYRUVIC ACID, ...
著者Ealick, S.E, Soriano, E.S.
登録日2007-07-26
公開日2008-03-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of the N47A and E109Q mutant proteins of pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii.
Acta Crystallogr.,Sect.D, 64, 2008
2QRO
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Human Deoxycytidine kinase dAMP, UDP, Mg ion product complex
分子名称: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Deoxycytidine kinase, MAGNESIUM ION, ...
著者Ealick, S.E, Soriano, E.V.
登録日2007-07-28
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Structures of human deoxycytidine kinase product complexes.
Acta Crystallogr.,Sect.D, 63, 2007
2QQC
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E109Q mutant of Pyruvoyl-dependent Arginine Decarboxylase from Methanococcus jannashii
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, AGMATINE, Pyruvoyl-dependent arginine decarboxylase subunit alpha, ...
著者Ealick, S.E, Soriano, E.S.
登録日2007-07-26
公開日2008-03-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of the N47A and E109Q mutant proteins of pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii.
Acta Crystallogr.,Sect.D, 64, 2008
2QRN
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Human Deoxycytidine kinase dCMP, UDP, Mg ion product complex
分子名称: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, Deoxycytidine kinase, MAGNESIUM ION, ...
著者Ealick, S.E, Soriano, E.V.
登録日2007-07-28
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structures of human deoxycytidine kinase product complexes.
Acta Crystallogr.,Sect.D, 63, 2007
2QJH
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M. jannaschii ADH synthase covalently bound to dihydroxyacetone phosphate
分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, Putative aldolase MJ0400
著者Ealick, S.E, Morar, M.
登録日2007-07-07
公開日2007-10-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid synthase, a catalyst in the archaeal pathway for the biosynthesis of aromatic amino acids.
Biochemistry, 46, 2007
2QJG
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M. jannaschii ADH synthase complexed with F1,6P
分子名称: 1,6-DI-O-PHOSPHONO-D-ALLITOL, Putative aldolase MJ0400
著者Ealick, S.E, Morar, M.
登録日2007-07-07
公開日2007-10-30
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid synthase, a catalyst in the archaeal pathway for the biosynthesis of aromatic amino acids.
Biochemistry, 46, 2007
2QRY
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Periplasmic thiamin binding protein
分子名称: THIAMIN PHOSPHATE, Thiamine-binding periplasmic protein
著者Ealick, S.E, Soriano, E.V.
登録日2007-07-30
公開日2008-02-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Similarities between Thiamin-Binding Protein and Thiaminase-I Suggest a Common Ancestor
Biochemistry, 47, 2008
2NSJ
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E. coli PurE H45Q mutant complexed with CAIR
分子名称: 5-AMINO-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, Phosphoribosylaminoimidazole carboxylase catalytic subunit
著者Ealick, S.E, Morar, M.
登録日2006-11-04
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献N(5)-CAIR Mutase: Role of a CO(2) Binding Site and Substrate Movement in Catalysis.
Biochemistry, 46, 2007
2NSL
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E. coli PurE H45N mutant complexed with CAIR
分子名称: 5-AMINO-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, Phosphoribosylaminoimidazole carboxylase catalytic subunit
著者Ealick, S.E, Morar, M.
登録日2006-11-04
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献N(5)-CAIR Mutase: Role of a CO(2) Binding Site and Substrate Movement in Catalysis.
Biochemistry, 46, 2007
2NSH
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E. coli PurE H45Q mutant complexed with nitro-AIR
分子名称: ((2R,3S,4R,5R)-5-(5-AMINO-4-NITRO-1H-IMIDAZOL-1-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL DIHYDROGEN PHOSPHATE, Phosphoribosylaminoimidazole carboxylase catalytic subunit
著者Ealick, S.E, Morar, M.
登録日2006-11-04
公開日2007-04-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献N(5)-CAIR Mutase: Role of a CO(2) Binding Site and Substrate Movement in Catalysis.
Biochemistry, 46, 2007
2HS0
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T. maritima PurL complexed with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Phosphoribosylformylglycinamidine synthase II
著者Ealick, S.E, Morar, M.
登録日2006-07-20
公開日2007-01-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily
Biochemistry, 45, 2006

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