6CHI
 
 | | Human Cytochrome P450 17A1 in complex with inhibitor: abiraterone C6 amide | | 分子名称: | 3-hydroxy-17-(3-pyridyl)-androst-5,16-dien-6-amide, PROTOPORPHYRIN IX CONTAINING FE, Steroid 17-alpha-hydroxylase/17,20 lyase | | 著者 | Scott, E.E. | | 登録日 | 2018-02-22 | | 公開日 | 2018-06-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.698 Å) | | 主引用文献 | Structure-Based Design of Inhibitors with Improved Selectivity for Steroidogenic Cytochrome P450 17A1 over Cytochrome P450 21A2.
J. Med. Chem., 61, 2018
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4QPI
 | | Crystal structure of hepatitis A virus | | 分子名称: | CHLORIDE ION, Capsid protein VP1, Capsid protein VP2, ... | | 著者 | Wang, X, Ren, J, Gao, Q, Hu, Z, Sun, Y, Li, X, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. | | 登録日 | 2014-06-23 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Hepatitis A virus and the origins of picornaviruses.
Nature, 517, 2015
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4IL3
 | | Crystal Structure of S. mikatae Ste24p | | 分子名称: | Ste24p, ZINC ION | | 著者 | Pryor Jr, E.E, Horanyi, P.S, Clark, K, Fedoriw, N, Connelly, S.M, Koszelak-Rosenblum, M, Zhu, G, Malkowski, M.G, Dumont, M.E, Wiener, M.C, Membrane Protein Structural Biology Consortium (MPSBC) | | 登録日 | 2012-12-28 | | 公開日 | 2013-02-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.102 Å) | | 主引用文献 | Structure of the integral membrane protein CAAX protease Ste24p.
Science, 339, 2013
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7AY8
 | | NMR solution structure of Tbo-IT2 | | 分子名称: | Tbo-IT2 | | 著者 | Mineev, K.S, Kornilov, F.D, Lushpa, V.A, Korolkova, Y.A, Maleeva, E.E, Andreev, Y.A, Kozlov, S.A, Arseniev, A.S. | | 登録日 | 2020-11-11 | | 公開日 | 2021-03-03 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | New Insectotoxin from Tibellus Oblongus Spider Venom Presents Novel Adaptation of ICK Fold.
Toxins, 13, 2021
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2IXR
 | | BipD of Burkholderia Pseudomallei | | 分子名称: | MEMBRANE ANTIGEN | | 著者 | Roversi, P, Johnson, S, Field, T, Deane, J.E, Galyov, E.E, Lea, S.M. | | 登録日 | 2006-07-10 | | 公開日 | 2006-11-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Self-Chaperoning of the Type III Secretion System Needle Tip Proteins Ipad and Bipd.
J.Biol.Chem., 282, 2007
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4U4H
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4X9Q
 | | MnSOD-3 Room Temperature Structure | | 分子名称: | MALONATE ION, MANGANESE (II) ION, SULFATE ION, ... | | 著者 | Hunter, G.J, Trinh, C.H, Hunter, T, Bonetta, R, Stewart, E.E. | | 登録日 | 2014-12-11 | | 公開日 | 2015-11-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | The structure of the Caenorhabditis elegans manganese superoxide dismutase MnSOD-3-azide complex.
Protein Sci., 24, 2015
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8EOH
 | | crystal structure of human Cytochrome P450 8B1 in complex with a C12-Pyridine Containing Steroid | | 分子名称: | 12-(pyridin-3-yl)-8alpha,10alpha,13alpha,14beta-androsta-4,11-diene-3,17-dione, 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Liu, J, Scott, E.E. | | 登録日 | 2022-10-03 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Pyridine-containing substrate analogs are restricted from accessing the human cytochrome P450 8B1 active site by tryptophan 281.
J.Biol.Chem., 299, 2023
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5UBO
 | | Mical-oxidized Actin complex with Gelsolin Segment 1 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Grintsevich, E.E, Sawaya, M.R, Reisler, E. | | 登録日 | 2016-12-21 | | 公開日 | 2017-12-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Catastrophic disassembly of actin filaments via Mical-mediated oxidation.
Nat Commun, 8, 2017
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7ZOL
 | | Cryo-EM structure of a CRISPR effector in complex with regulator | | 分子名称: | Cas7-11, TPR-CHAT, ZINC ION, ... | | 著者 | Babatunde, E.E, Davide, T, Bertrand, B, Sergey, N, Alexander, M, Henning, S, Dong, C.N. | | 登録日 | 2022-04-26 | | 公開日 | 2022-11-30 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Structural insights into the regulation of Cas7-11 by TPR-CHAT.
Nat.Struct.Mol.Biol., 30, 2023
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7ZOQ
 | | Cryo-EM structure of a CRISPR effector in complex with a caspase regulator | | 分子名称: | RNA (39-MER), TPR-CHAT, ZINC ION, ... | | 著者 | Babatunde, E.E, Davide, T, Bertrand, B, Sergey, N, Alexander, M, Henning, S, Dong, C.N. | | 登録日 | 2022-04-26 | | 公開日 | 2022-11-30 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into the regulation of Cas7-11 by TPR-CHAT.
Nat.Struct.Mol.Biol., 30, 2023
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5V2S
 | | Crystal structure of glycoprotein B from Herpes Simplex Virus type I | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein B | | 著者 | Cooper, R.S, Heldwein, E.E. | | 登録日 | 2017-03-06 | | 公開日 | 2018-05-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural basis for membrane anchoring and fusion regulation of the herpes simplex virus fusogen gB.
Nat. Struct. Mol. Biol., 25, 2018
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5UYS
 | | Human steroidogenic cytochrome P450 17A1 with 3alphaOH-5alpha-abiraterone analog | | 分子名称: | (3alpha,5alpha,8alpha)-17-(pyridin-3-yl)androst-16-en-3-ol, PROTOPORPHYRIN IX CONTAINING FE, Steroid 17-alpha-hydroxylase/17,20 lyase | | 著者 | Scott, E.E, Petrunak, E.M. | | 登録日 | 2017-02-24 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.392 Å) | | 主引用文献 | Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site.
J.Biol.Chem., 299, 2023
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7FGN
 | | The crystal structure of the FAF1 UBL1 | | 分子名称: | FAS-associated factor 1 | | 著者 | Kim, E.E, ParK, J.K, Shin, S.C. | | 登録日 | 2021-07-27 | | 公開日 | 2022-07-27 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.199 Å) | | 主引用文献 | The complex of Fas-associated factor 1 with Hsp70 stabilizes the adherens junction integrity by suppressing RhoA activation
J Mol Cell Biol, 14, 2022
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7QBY
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7FGM
 | | The complex crystals structure of the FAF1 UBL1_L-Hsp70 NBD with ADP and phosphate | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FAS-associated factor 1, Heat shock 70 kDa protein 1A, ... | | 著者 | Kim, E.E, ParK, J.K, Shin, S.C. | | 登録日 | 2021-07-27 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The complex of Fas-associated factor 1 with Hsp70 stabilizes the adherens junction integrity by suppressing RhoA activation
J Mol Cell Biol, 14, 2022
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8ITP
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8ITN
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7QI2
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5D8A
 | | Crystal structure of recombinant foot-and-mouth-disease virus A22-H2093F empty capsid | | 分子名称: | VP1, VP2, VP3, ... | | 著者 | Kotecha, A, Seago, J, Scott, K, Burman, A, Loureiro, S, Ren, J, Porta, C, Ginn, H.M, Jackson, T, Perez-Martin, E, Siebert, C.A, Paul, G, Huiskonen, J.T, Jones, I.M, Esnouf, R.M, Fry, E.E, Maree, F.F, Charleston, B, Stuart, D.I. | | 登録日 | 2015-08-16 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design.
Nat.Struct.Mol.Biol., 22, 2015
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3EBS
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5DDJ
 | | Crystal structure of recombinant foot-and-mouth-disease virus O1M-S2093Y empty capsid | | 分子名称: | Foot and mouth disease virus, VP1, VP2, ... | | 著者 | Kotecha, A, Seago, J, Scott, K, Burman, A, Loureiro, S, Ren, J, Porta, C, Ginn, H.M, Jackson, T, Perez-Martin, E, Siebert, C.A, Paul, G, Huiskonen, J.T, Jones, I.M, Esnouf, R.M, Fry, E.E, Maree, F.F, Charleston, B, Stuart, D.I. | | 登録日 | 2015-08-25 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design.
Nat.Struct.Mol.Biol., 22, 2015
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3E6I
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3E21
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5CXF
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