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PDB: 41042 件

8FRB
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Mouse acidic mammalian chitinase, catalytic domain in complex with N,N'-diacetylchitobiose at pH 5.25
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetylamino-2-deoxy-alpha-L-idopyranose, ...
著者Diaz, R.E, Fraser, J.S.
登録日2023-01-06
公開日2023-03-08
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase.
Biorxiv, 2024
6YDD
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X-ray structure of LPMO.
分子名称: COPPER (II) ION, LPMO lytic polysaccharide monooxygenase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, ...
著者Tandrup, T, Tryfona, T, Frandsen, K.E.H, Johansen, K.S, Dupree, P, Lo Leggio, L.
登録日2020-03-20
公開日2020-09-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Oligosaccharide Binding and Thermostability of Two Related AA9 Lytic Polysaccharide Monooxygenases.
Biochemistry, 59, 2020
1KKQ
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Crystal structure of the human PPAR-alpha ligand-binding domain in complex with an antagonist GW6471 and a SMRT corepressor motif
分子名称: N-((2S)-2-({(1Z)-1-METHYL-3-OXO-3-[4-(TRIFLUOROMETHYL) PHENYL]PROP-1-ENYL}AMINO)-3-{4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL}PROPYL)PROPANAMIDE, NUCLEAR RECEPTOR CO-REPRESSOR 2, PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR
著者Xu, H.E, Stanley, T.B, Montana, V.G, Lambert, M.H, Shearer, B.G, Cobb, J.E, McKee, D.D, Galardi, C.M, Nolte, R.T, Parks, D.J.
登録日2001-12-10
公開日2002-02-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha.
Nature, 415, 2002
4N56
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Binary complex structure of Klenow fragment of Taq DNA polymerase I707L mutant (Cs3C KlenTaq) with DNA
分子名称: 5'-D(*AP*AP*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3', DNA polymerase I, ...
著者Wu, E.Y.
登録日2013-10-09
公開日2015-01-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A Conservative Isoleucine to Leucine Mutation Causes Major Rearrangements and Cold Sensitivity in KlenTaq1 DNA Polymerase.
Biochemistry, 54, 2015
6QT2
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Radiation damage study on a 16mer DNA segment, structure at 6.2 MGy dose
分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*TP*GP*GP*AP*AP*AP*TP*TP*TP*CP*CP*AP*GP*C)-3')
著者Bugris, V, Harmat, V, Ferenc, G, Brockhauser, S, Carmichael, I, Garman, E.F.
登録日2019-02-22
公開日2019-07-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Radiation-damage investigation of a DNA 16-mer.
J.Synchrotron Radiat., 26, 2019
6HSK
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Crystal structure of a human HDAC8 L6 loop mutant complexed with Quisinostat
分子名称: 2-[4-[[(1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-~{N}-oxidanyl-pyrimidine-5-carboxamide, Histone deacetylase 8, POTASSIUM ION, ...
著者Marek, M, Shaik, T.B, Ramos-Morales, E, Romier, C.
登録日2018-10-01
公開日2018-10-31
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.096 Å)
主引用文献Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants.
J. Med. Chem., 61, 2018
6QRF
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Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with inhibitor
分子名称: (phenylmethyl) 1~{H}-pyrazole-4-carboxylate, SULFATE ION, tRNA (guanine-N(1)-)-methyltransferase
著者Thomas, S.E, Whitehouse, A.J, Coyne, A.G, Abell, C, Mendes, V, Blundell, T.L.
登録日2019-02-19
公開日2019-09-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Development of Inhibitors againstMycobacterium abscessustRNA (m1G37) Methyltransferase (TrmD) Using Fragment-Based Approaches.
J.Med.Chem., 62, 2019
2JWA
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ErbB2 transmembrane segment dimer spatial structure
分子名称: Receptor tyrosine-protein kinase erbB-2
著者Mineev, K.S, Bocharov, E.V, Arseniev, A.S.
登録日2007-10-09
公開日2008-01-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Spatial Structure of the Dimeric Transmembrane Domain of the Growth Factor Receptor ErbB2 Presumably Corresponding to the Receptor Active State
J.Biol.Chem., 283, 2008
7KQ8
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Structure of iron bound MEMO1
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FE (II) ION, ...
著者Boniecki, M.T, Uhlemann, E.E, Dmitriev, O.Y.
登録日2020-11-13
公開日2021-11-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献MEMO1 binds iron and modulates iron homeostasis in cancer cells.
Elife, 13, 2024
6QT6
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Radiation damage study on a 16mer DNA segment, structure at 29.2 MGy dose
分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*TP*GP*GP*AP*AP*AP*TP*TP*TP*CP*CP*AP*GP*C)-3')
著者Bugris, V, Harmat, V, Ferenc, G, Brockhauser, S, Carmichael, I, Garman, E.F.
登録日2019-02-22
公開日2019-07-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Radiation-damage investigation of a DNA 16-mer.
J.Synchrotron Radiat., 26, 2019
8FRD
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Mouse acidic mammalian chitinase, catalytic domain in complex with N,N'-diacetylchitobiose at pH 5.25
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acidic mammalian chitinase, MAGNESIUM ION
著者Diaz, R.E, Fraser, J.S.
登録日2023-01-06
公開日2023-03-15
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase.
Biorxiv, 2024
6QTA
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Crystal structure of Rea1-MIDAS/Rsa4-UBL complex from Chaetomium thermophilum
分子名称: GLYCEROL, MAGNESIUM ION, Midasin,Midasin, ...
著者Ahmed, Y.L, Thoms, M, Hurt, E, Sinning, I.
登録日2019-02-22
公開日2019-08-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal structures of Rea1-MIDAS bound to its ribosome assembly factor ligands resembling integrin-ligand-type complexes.
Nat Commun, 10, 2019
6QS9
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Bovine Serum Albumin in complex with Ketoprofen
分子名称: (R)-Ketoprofen, CALCIUM ION, Serum albumin
著者Donini, S, Parisini, E.
登録日2019-02-20
公開日2019-09-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献Biohybrid Electrospun Membrane for the Filtration of Ketoprofen Drug from Water.
Acs Omega, 4, 2019
5SYG
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BU of 5syg by Molmil
Cryo-EM reconstruction of zampanolide-bound microtubule
分子名称: (2Z,4E)-N-[(S)-[(1S,2E,5S,8E,10Z,17S)-3,11-dimethyl-19-methylidene-7,13-dioxo-6,21-dioxabicyclo[15.3.1]henicosa-2,8,10-trien-5-yl](hydroxy)methyl]hexa-2,4-dienamide, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Kellogg, E.H, Hejab, N.M.A, Nogales, E.
登録日2016-08-11
公開日2017-02-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures.
J. Mol. Biol., 429, 2017
8R65
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1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains
分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2023-11-20
公開日2024-03-27
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (4.23 Å)
主引用文献Structural and functional characterization of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA polymerase II.
J.Virol., 98, 2024
2NXF
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Crystal Structure of a dimetal phosphatase from Danio rerio LOC 393393
分子名称: ETHANOL, PHOSPHATE ION, Putative dimetal phosphatase, ...
著者Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, McCoy, J.G, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
登録日2006-11-17
公開日2006-12-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of a dimetal phosphatase from Danio rerio LOC 393393
To be Published
6QSN
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Crystal structure of Yellow fever virus polymerase NS5A
分子名称: Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
著者Boura, E, Dubankova, A.
登録日2019-02-21
公開日2019-10-16
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献Structure of the yellow fever NS5 protein reveals conserved drug targets shared among flaviviruses.
Antiviral Res., 169, 2019
6QT1
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Radiation damage study on a 16mer DNA segment, structure at 0.48 MGy dose
分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*TP*GP*GP*AP*AP*AP*TP*TP*TP*CP*CP*AP*GP*C)-3')
著者Bugris, V, Harmat, V, Ferenc, G, Brockhauser, S, Carmichael, I, Garman, E.F.
登録日2019-02-22
公開日2019-07-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Radiation-damage investigation of a DNA 16-mer.
J.Synchrotron Radiat., 26, 2019
6QT4
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Radiation damage study on a 16mer DNA segment, structure at 17.7 MGy dose
分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*TP*GP*GP*AP*AP*AP*TP*TP*TP*CP*CP*AP*GP*C)-3')
著者Bugris, V, Harmat, V, Ferenc, G, Brockhauser, S, Carmichael, I, Garman, E.F.
登録日2019-02-22
公開日2019-07-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Radiation-damage investigation of a DNA 16-mer.
J.Synchrotron Radiat., 26, 2019
8FR9
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Mouse acidic mammalian chitinase, catalytic domain in complex with N,N'-diacetylchitobiose at pH 5.08
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acidic mammalian chitinase, ...
著者Diaz, R.E, Fraser, J.S.
登録日2023-01-06
公開日2023-03-15
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase.
Biorxiv, 2024
8FRG
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Mouse acidic mammalian chitinase, catalytic domain in complex with N,N'-diacetylchitobiose at pH 5.43
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acidic mammalian chitinase, ...
著者Diaz, R.E, Fraser, J.S.
登録日2023-01-06
公開日2023-03-15
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase.
Biorxiv, 2024
8C84
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Crystal structure of MADS-box/MEF2D N-terminal domain complex
分子名称: DNA (5'-D(P*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3'), DNA (5'-D(P*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*TP*T)-3'), MEF2D protein
著者Chinellato, M, Carli, A, Perin, S, Mazzoccato, Y, Di Giorgio, E, Brancolini, C, Angelini, A, Cendron, L.
登録日2023-01-18
公開日2024-01-31
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.
J.Mol.Biol., 436, 2024
2NV9
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The X-ray Crystal Structure of the Paramecium bursaria Chlorella virus arginine decarboxylase
分子名称: A207R protein, arginine decarboxylase, PYRIDOXAL-5'-PHOSPHATE
著者Shah, R.H, Akella, R, Goldsmith, E, Phillips, M.A.
登録日2006-11-11
公開日2007-03-20
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献X-ray Structure of Paramecium bursaria Chlorella Virus Arginine Decarboxylase: Insight into the Structural Basis for Substrate Specificity.
Biochemistry, 46, 2007
6QW2
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The Transcriptional Regulator PrfA-A218G mutant from Listeria Monocytogenes
分子名称: ISOPROPYL ALCOHOL, Listeriolysin positive regulatory factor A, SODIUM ION
著者Hall, M, Grundstrom, C, Hansen, S, Brannstrom, K, Johansson, J, Sauer-Eriksson, A.E.
登録日2019-03-05
公開日2020-04-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Novel Growth-Based Selection Strategy Identifies New Constitutively Active Variants of the Major Virulence Regulator PrfA in Listeria monocytogenes.
J.Bacteriol., 202, 2020
6JKS
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Crystal structure of aspartate transcarbamoylase from Trypanosoma cruzi in complex with carbamoyl phosphate (CP) and aspartate (Asp)
分子名称: ASPARTIC ACID, Aspartate carbamoyltransferase, putative, ...
著者Matoba, K, Shiba, T, Nara, T, Aoki, T, Nagasaki, S, Hayamizu, R, Honma, T, Tanaka, A, Inoue, M, Matsuoka, S, Balogun, E.O, Inaoka, D.K, Kita, K, Harada, S.
登録日2019-03-01
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic snapshots of Trypanosoma cruzi aspartate transcarbamoylase revealed an ordered Bi-Bi reaction mechanism
To Be Published

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件を2024-10-09に公開中

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