8CIN
| BA.4/5-5 FAB IN COMPLEX WITH SARS-COV-2 BA.4 SPIKE GLYCOPROTEIN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA.4/5-5 fab HEAVY CHAIN, ... | 著者 | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I, Fry, E.E. | 登録日 | 2023-02-10 | 公開日 | 2024-02-21 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86. Nat Commun, 15, 2024
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8T9Y
| Structure of VHH-Fab complex with engineered Elbow FNQIKG and Crystal Kappa regions | 分子名称: | DI(HYDROXYETHYL)ETHER, Fab heavy chain, Fab light chain, ... | 著者 | Filippova, E.V, Thompson, I, Kossiakoff, A.A. | 登録日 | 2023-06-26 | 公開日 | 2023-11-29 | 最終更新日 | 2024-01-03 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci., 33, 2024
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8T8I
| Structure of VHH-Fab complex with engineered Elbow FNQIKG, Crystal Kappa and SER substitutions | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Fab heavy chain, ... | 著者 | Filippova, E.V, Thompson, I, Kossiakoff, A.A. | 登録日 | 2023-06-22 | 公開日 | 2023-11-29 | 最終更新日 | 2024-01-03 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci., 33, 2024
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6UTN
| Native E. coli Glyceraldehyde 3-phosphate dehydrogenase | 分子名称: | ACETATE ION, Glyceraldehyde-3-phosphate dehydrogenase, PHOSPHATE ION, ... | 著者 | Rodriguez-Hernandez, A, Romo-Arevalo, E, Rodriguez-Romero, A. | 登録日 | 2019-10-29 | 公開日 | 2019-12-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | A Novel Substrate-Binding Site in the X-Ray Structure of an Oxidized E. coli Glyceraldehyde 3-Phosphate Dehydrogenase Elucidated by Single-Wavelength Anomalous Dispersion Crystals, 9, 2019
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4XAJ
| Crystal structure of human NR2E1/TLX | 分子名称: | Atrophin/grunge, Maltose-binding periplasmic protein,Nuclear receptor subfamily 2 group E member 1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Zhi, X, Zhou, E, Xu, E. | 登録日 | 2014-12-14 | 公開日 | 2015-03-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.551 Å) | 主引用文献 | Structural basis for corepressor assembly by the orphan nuclear receptor TLX. Genes Dev., 29, 2015
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7MXY
| Cryo-EM structure of PfFNT-inhibitor complex | 分子名称: | (Z)-4,4,5,5,5-pentakis(fluoranyl)-1-(4-methoxy-2-oxidanyl-phenyl)-3-oxidanyl-pent-2-en-1-one, Formate-nitrite transporter | 著者 | Yu, E.W, Su, C, Lyu, M. | 登録日 | 2021-05-19 | 公開日 | 2021-12-08 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.18 Å) | 主引用文献 | Structural basis of transport and inhibition of the Plasmodium falciparum transporter PfFNT EMBO Rep, 22, 2021
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8EUJ
| Class2 of the INO80-Nucleosome complex | 分子名称: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F. | 登録日 | 2022-10-18 | 公開日 | 2023-07-12 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
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5M0T
| Alpha-ketoglutarate-dependent non-heme iron oxygenase EasH | 分子名称: | 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent non-heme iron oxygenase EasH, FE (II) ION, ... | 著者 | Jakubczyk, D, Caputi, L, Stevenson, C.E.M, Lawson, D.M, O'Connor, S.E. | 登録日 | 2016-10-05 | 公開日 | 2016-12-07 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural characterization of EasH (Aspergillus japonicus) - an oxidase involved in cycloclavine biosynthesis. Chem. Commun. (Camb.), 52, 2016
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8ETT
| Class1 of the INO80-Hexasome complex | 分子名称: | DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. | 登録日 | 2022-10-17 | 公開日 | 2023-07-12 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (6.68 Å) | 主引用文献 | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
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8ETV
| Class2 of the INO80-Hexasome complex | 分子名称: | DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. | 登録日 | 2022-10-17 | 公開日 | 2023-07-12 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
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5M30
| Structure of TssK from T6SS EAEC in complex with nanobody nb18 | 分子名称: | Anti-vesicular stomatitis virus N VHH, Type VI secretion protein | 著者 | Nguyen, V.S, Cambillau, C, Spinelli, C, Desmyter, A, Legrand, P, Cascales, E. | 登録日 | 2016-10-13 | 公開日 | 2017-06-21 | 最終更新日 | 2017-09-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex. Nat Microbiol, 2, 2017
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8EU2
| Class3 of the INO80-Hexasome complex | 分子名称: | DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. | 登録日 | 2022-10-18 | 公開日 | 2023-07-12 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
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7Z0W
| E. coli NfsA bound to NADP+ | 分子名称: | 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, ... | 著者 | White, S.A, Grainger, A, Parr, R, Day, M.A, Jarrom, D, Graziano, A, Searle, P.F, Hyde, E.I. | 登録日 | 2022-02-23 | 公開日 | 2022-07-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | The 3D-structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP + provide glimpses of its catalytic mechanism. Febs Lett., 596, 2022
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6YBK
| Structure of MBP-Mcl-1 in complex with compound 4d | 分子名称: | (2~{R})-2-[5-[3-chloranyl-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy-3-[2-(pyrazin-2-ylmethoxy)phenyl]propanoic acid, CHLORIDE ION, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, ... | 著者 | Dokurno, P, Surgenor, A.E, Murray, J.B. | 登録日 | 2020-03-17 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of S64315, a Potent and Selective Mcl-1 Inhibitor. J.Med.Chem., 63, 2020
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7A3S
| Crystal structure of dengue 3 virus envelope glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, SULFATE ION | 著者 | Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Navarro-Sanchez, E, Rey, F.A. | 登録日 | 2020-08-18 | 公開日 | 2021-12-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses. Cell, 184, 2021
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6XZR
| Influenza C virus polymerase in complex with chicken ANP32A - Subclass 1 | 分子名称: | LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... | 著者 | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | 登録日 | 2020-02-05 | 公開日 | 2020-11-25 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
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8F28
| Lysozyme Structures from Single-Entity Crystallization Method NanoAC | 分子名称: | ACETATE ION, CHLORIDE ION, Lysozyme C, ... | 著者 | Yang, R, Sankaran, B, Ogbonna, E, Wang, G. | 登録日 | 2022-11-07 | 公開日 | 2023-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | A Single-Entity Method for Actively Controlled Nucleation and High-Quality Protein Crystal Synthesis. Anal.Chem., 95, 2023
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7PZD
| Cryo-EM structure of the NLRP3 PYD filament | 分子名称: | NACHT, LRR and PYD domains-containing protein 3 | 著者 | Hochheiser, I.V, Hagelueken, G, Behrmann, H, Behrmann, E, Geyer, M. | 登録日 | 2021-10-12 | 公開日 | 2022-04-20 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Directionality of PYD filament growth determined by the transition of NLRP3 nucleation seeds to ASC elongation. Sci Adv, 8, 2022
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8EUE
| Class1 of the INO80-Nucleosome complex | 分子名称: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | 著者 | Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F. | 登録日 | 2022-10-18 | 公開日 | 2023-07-12 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
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6S51
| The crystal structure of glycogen phosphorylase in complex with 10 | 分子名称: | (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(2-phenyl-1,3-thiazol-4-yl)oxane-3,4,5-triol, Glycogen phosphorylase, muscle form, ... | 著者 | Kyriakis, E, Solovou, T.G.A, Papaioannou, O.S.E, Skamnaki, V.T, Leonidas, D.D. | 登録日 | 2019-06-29 | 公開日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | The architecture of hydrogen and sulfur sigma-hole interactions explain differences in the inhibitory potency of C-beta-d-glucopyranosyl thiazoles, imidazoles and an N-beta-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design. Bioorg.Med.Chem., 28, 2020
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7N9F
| Structure of the in situ yeast NPC | 分子名称: | Dynein light chain 1, cytoplasmic, Nucleoporin 145c, ... | 著者 | Villa, E, Singh, D, Ludtke, S.J, Akey, C.W, Rout, M.P, Echeverria, I, Suslov, S. | 登録日 | 2021-06-17 | 公開日 | 2022-01-26 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (37 Å) | 主引用文献 | Comprehensive structure and functional adaptations of the yeast nuclear pore complex. Cell, 185, 2022
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7NGJ
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7NGD
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7NGO
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8EOH
| crystal structure of human Cytochrome P450 8B1 in complex with a C12-Pyridine Containing Steroid | 分子名称: | 12-(pyridin-3-yl)-8alpha,10alpha,13alpha,14beta-androsta-4,11-diene-3,17-dione, 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Liu, J, Scott, E.E. | 登録日 | 2022-10-03 | 公開日 | 2023-08-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Pyridine-containing substrate analogs are restricted from accessing the human cytochrome P450 8B1 active site by tryptophan 281. J.Biol.Chem., 299, 2023
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