1AF6
 
 | | MALTOPORIN SUCROSE COMPLEX | | Descriptor: | MAGNESIUM ION, MALTOPORIN, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | Authors: | Dutzler, R, Schirmer, T. | | Deposit date: | 1997-03-21 | | Release date: | 1998-03-25 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Channel specificity: structural basis for sugar discrimination and differential flux rates in maltoporin.
J.Mol.Biol., 272, 1997
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4WIT
 | | TMEM16 lipid scramblase in crystal form 2 | | Descriptor: | CALCIUM ION, Predicted protein | | Authors: | Dutzler, R, Brunner, J.D, Lim, N.K, Schenck, S. | | Deposit date: | 2014-09-26 | | Release date: | 2014-11-12 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | X-ray structure of a calcium-activated TMEM16 lipid scramblase.
Nature, 516, 2014
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4WIS
 | | Crystal structure of the lipid scramblase nhTMEM16 in crystal form 1 | | Descriptor: | CALCIUM ION, lipid scramblase | | Authors: | Dutzler, R, Brunner, J.D, Lim, N.K, Schenck, S. | | Deposit date: | 2014-09-26 | | Release date: | 2014-11-12 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | X-ray structure of a calcium-activated TMEM16 lipid scramblase.
Nature, 516, 2014
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2D4Z
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5DA0
 | | Structure of the the SLC26 transporter SLC26Dg in complex with a nanobody | | Descriptor: | DECYL-BETA-D-MALTOPYRANOSIDE, Nanobody, Sulphate transporter | | Authors: | Dutzler, R, Geertsma, E.R, Chang, Y, Shaik, F.R. | | Deposit date: | 2015-08-19 | | Release date: | 2015-09-09 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family.
Nat.Struct.Mol.Biol., 22, 2015
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5DA4
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1OTS
 | | Structure of the Escherichia coli ClC Chloride channel and Fab Complex | | Descriptor: | CHLORIDE ION, Fab fragment (heavy chain), Fab fragment (light chain), ... | | Authors: | Dutzler, R, Campbell, E.B, MacKinnon, R. | | Deposit date: | 2003-03-22 | | Release date: | 2003-04-15 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
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1OTU
 | | Structure of the Escherichia coli ClC Chloride channel E148Q mutant and Fab Complex | | Descriptor: | CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... | | Authors: | Dutzler, R, Campbell, E.B, MacKinnon, R. | | Deposit date: | 2003-03-23 | | Release date: | 2003-04-15 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
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1OTT
 | | Structure of the Escherichia coli ClC Chloride channel E148A mutant and Fab Complex | | Descriptor: | CHLORIDE ION, Fab fragment (Heavy chain), Fab fragment (Light chain), ... | | Authors: | Dutzler, R, Campbell, E.B, MacKinnon, R. | | Deposit date: | 2003-03-23 | | Release date: | 2003-04-15 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
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5M94
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1MPQ
 | | MALTOPORIN TREHALOSE COMPLEX | | Descriptor: | MALTOPORIN, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose | | Authors: | Dutzler, R, Schirmer, T. | | Deposit date: | 1997-03-24 | | Release date: | 1998-03-25 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Channel specificity: structural basis for sugar discrimination and differential flux rates in maltoporin.
J.Mol.Biol., 272, 1997
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1KPK
 | | Crystal Structure of the ClC Chloride Channel from E. coli | | Descriptor: | putative channel transporter | | Authors: | Dutzler, R, Campbell, E.B, Cadene, M, Chait, B.T, MacKinnon, R. | | Deposit date: | 2001-12-31 | | Release date: | 2002-01-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of
anion selectivity.
Nature, 415, 2002
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1KPL
 | | Crystal Structure of the ClC Chloride Channel from S. typhimurium | | Descriptor: | CHLORIDE ION, N-OCTANE, PENTADECANE, ... | | Authors: | Dutzler, R, Campbell, E.B, Cadene, M, Chait, B.T, MacKinnon, R. | | Deposit date: | 2001-12-31 | | Release date: | 2002-01-23 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of
anion selectivity.
Nature, 415, 2002
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1OSM
 | | OSMOPORIN (OMPK36) FROM KLEBSIELLA PNEUMONIAE | | Descriptor: | DODECANE, OMPK36 | | Authors: | Dutzler, R, Schirmer, T. | | Deposit date: | 1999-01-08 | | Release date: | 1999-07-26 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structure and functional characterization of OmpK36, the osmoporin of Klebsiella pneumoniae.
Structure Fold.Des., 7, 1999
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5IOF
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1MPM
 | | MALTOPORIN MALTOSE COMPLEX | | Descriptor: | MAGNESIUM ION, MALTOPORIN, alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose | | Authors: | Dutzler, R, Schirmer, T. | | Deposit date: | 1996-01-11 | | Release date: | 1997-03-12 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structures of various maltooligosaccharides bound to maltoporin reveal a specific sugar translocation pathway.
Structure, 4, 1996
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1MPO
 | | MALTOPORIN MALTOHEXAOSE COMPLEX | | Descriptor: | MAGNESIUM ION, MALTOPORIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Dutzler, R, Schirmer, T. | | Deposit date: | 1996-01-11 | | Release date: | 1997-03-12 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structures of various maltooligosaccharides bound to maltoporin reveal a specific sugar translocation pathway.
Structure, 4, 1996
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1MPN
 | | MALTOPORIN MALTOTRIOSE COMPLEX | | Descriptor: | MAGNESIUM ION, MALTOPORIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Dutzler, R, Schirmer, T. | | Deposit date: | 1996-01-11 | | Release date: | 1997-03-12 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structures of various maltooligosaccharides bound to maltoporin reveal a specific sugar translocation pathway.
Structure, 4, 1996
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5OCL
 | | Nanobody-anti-VGLUT nanobody complex | | Descriptor: | anti-llama nanobody, anti-vglut nanobody | | Authors: | Dutzler, R, Schenck, S, Kunz, L. | | Deposit date: | 2017-07-03 | | Release date: | 2017-07-26 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Generation and Characterization of Anti-VGLUT Nanobodies Acting as Inhibitors of Transport.
Biochemistry, 56, 2017
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7ZK3
 | | Structure of 1PBC- and calcium-bound mTMEM16A(ac) chloride channel at 2.85 A resolution | | Descriptor: | 1-Hydroxy-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile, Anoctamin-1, CALCIUM ION | | Authors: | Lam, A.K.M, Rutz, S, Dutzler, R. | | Deposit date: | 2022-04-12 | | Release date: | 2022-05-25 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC.
Nat Commun, 13, 2022
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9EZC
 | | Structure of the extracellular subdomain of a homomeric LRRC8C truncation disease mutant | | Descriptor: | Volume-regulated anion channel subunit LRRC8C | | Authors: | Rutz, S, Quinodoz, M, Peter, V, Garavelli, L, Innes, M.A, Kellenberger, S, Peng, Z, Barone, A, Campos-Xavier, B, Unger, S, Rivolta, C, Dutzler, R, Superti-Furga, A. | | Deposit date: | 2024-04-11 | | Release date: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Genetic activation of Volume-Regulated Anion Channels cause a multisystem disorder
To Be Published
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9F16
 | | Structure of a homomeric LRRC8C point mutation disease mutant | | Descriptor: | Volume-regulated anion channel subunit LRRC8C | | Authors: | Rutz, S, Quinodoz, M, Peter, V, Garavelli, L, Innes, M.A, Kellenberger, S, Peng, Z, Barone, A, Campos-Xavier, B, Unger, S, Rivolta, C, Dutzler, R, Superti-Furga, A. | | Deposit date: | 2024-04-18 | | Release date: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Genetic activation of Volume-Regulated Anion Channels causes a multisystem disorder
To Be Published
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8ONT
 | | Structure of Setaria italica NRAT in complex with a nanobody | | Descriptor: | DIUNDECYL PHOSPHATIDYL CHOLINE, NRAMP related aluminium transporter, Nanobody1 | | Authors: | Ramanadane, K, Liziczai, M, Markovic, D, Straub, M.S, Rosalen, G.T, Udovcic, A, Dutzler, R, Manatschal, C. | | Deposit date: | 2023-04-03 | | Release date: | 2023-04-12 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | Structural and functional properties of a plant NRAMP-related aluminum transporter.
Elife, 12, 2023
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8OPQ
 | | Structure of Human Solute Carrier 26 family member A6 (SLC26A6) anion transporter in an inward-facing state | | Descriptor: | CHLORIDE ION, Solute carrier family 26 member 6 | | Authors: | Tippett, D.N, Breen, C, Butler, S.J, Sawicka, M, Dutzler, R. | | Deposit date: | 2023-04-07 | | Release date: | 2023-05-17 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Structural and functional properties of the transporter SLC26A6 reveal mechanism of coupled anion exchange.
Elife, 12, 2023
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2VL0
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