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PDB: 88 件

6OF6
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BU of 6of6 by Molmil
Crystal structure of tRNA^ Ala(GGC) bound to cognate 70S A-site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Sunita, S, Dunham, C.M.
登録日2019-03-28
公開日2020-06-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
7N8Y
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BU of 7n8y by Molmil
Oxidized PheRS G318W from Salmonella enterica serovar Typhimurium
分子名称: Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit
著者Srinivas, P, Dunham, C.M.
登録日2021-06-16
公開日2021-10-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Oxidation alters the architecture of the phenylalanyl-tRNA synthetase editing domain to confer hyperaccuracy.
Nucleic Acids Res., 49, 2021
8FON
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BU of 8fon by Molmil
Crystal structure of tRNA^Lys(SUU) bound to AUA codon in the ribosomal P site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
登録日2023-01-02
公開日2023-03-29
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.64 Å)
主引用文献Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches.
J.Biol.Chem., 299, 2023
8FOM
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BU of 8fom by Molmil
Crystal structure of tRNA^Lys(SUU) bound to UAA codon in the ribosomal P site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
登録日2023-01-02
公開日2023-03-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.58 Å)
主引用文献Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches.
J.Biol.Chem., 299, 2023
8FR3
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BU of 8fr3 by Molmil
E. coli EF-Tu in complex with KKL-55
分子名称: 3-chloro-N-(1-propyl-1H-tetrazol-5-yl)benzamide, Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, ...
著者Nguyen, H.A, Kuzmishin Nagy, A.B, Dunham, C.M.
登録日2023-01-06
公開日2023-09-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Antibiotic that inhibits trans -translation blocks binding of EF-Tu to tmRNA but not to tRNA.
Mbio, 14, 2023
1VVJ
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BU of 1vvj by Molmil
Crystal Structure of Frameshift Suppressor tRNA SufA6 bound to Codon CCC-G on the Ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Maehigashi, T, Dunkle, J.A, Dunham, C.M.
登録日2013-05-24
公開日2014-08-06
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.440001 Å)
主引用文献Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
5DFE
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BU of 5dfe by Molmil
70S termination complex containing E. coli RF2
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Hoffer, E.D, Dunham, C.M.
登録日2015-08-26
公開日2016-10-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.09997559 Å)
主引用文献Uniformity of Peptide Release Is Maintained by Methylation of Release Factors.
Cell Rep, 17, 2016
5CZP
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BU of 5czp by Molmil
70S termination complex containing E. coli RF2
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Dunham, C.M.
登録日2015-07-31
公開日2016-10-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.29995918 Å)
主引用文献Uniformity of Peptide Release Is Maintained by Methylation of Release Factors.
Cell Rep, 17, 2016
4YZV
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BU of 4yzv by Molmil
Precleavage 70S structure of the P. vulgaris HigB deltaH92 toxin bound to the ACA codon
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Schureck, M.A, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
登録日2015-03-25
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZSN
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BU of 4zsn by Molmil
70S-wild-type HigB toxin complex bound to a AAA lysine codon
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Schureck, M.A, Dunham, C.M.
登録日2015-05-13
公開日2016-09-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Mechanism of endonuclease cleavage by the HigB toxin.
Nucleic Acids Res., 44, 2016
4YPB
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BU of 4ypb by Molmil
Precleavage 70S structure of the P. vulgaris HigB DeltaH92 toxin bound to the AAA codon
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Schureck, M.A, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
登録日2015-03-12
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YY3
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BU of 4yy3 by Molmil
30S ribosomal subunit- HigB complex
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Schureck, M.A, Maehigashi, T, Dunham, C.M.
登録日2015-03-23
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献mRNA bound to the 30S subunit is a HigB toxin substrate.
Rna, 22, 2016
4OX9
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BU of 4ox9 by Molmil
Crystal structure of the aminoglycoside resistance methyltransferase NpmA bound to the 30S ribosomal subunit
分子名称: 16S rRNA, 16S rRNA (adenine(1408)-N(1))-methyltransferase, 30S ribosomal protein S10, ...
著者Dunkle, J.A, Conn, G.L, Dunham, C.M.
登録日2014-02-04
公開日2014-04-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.8035 Å)
主引用文献Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.
Proc.Natl.Acad.Sci.USA, 111, 2014
4P70
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BU of 4p70 by Molmil
Crystal Structure of Unmodified tRNA Proline (CGG) Bound to Codon CCG on the Ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Maehigashi, T, Dunkle, J.A, Dunham, C.M.
登録日2014-03-25
公開日2014-08-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.68 Å)
主引用文献Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4P6F
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BU of 4p6f by Molmil
Crystal structure of the peptolide 12C bound to bacterial ribosome
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fagan, C.E, Dunham, C.M.
登録日2014-03-24
公開日2014-10-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Macrolide-Peptide Conjugates as Probes of the Path of Travel of the Nascent Peptides through the Ribosome.
Acs Chem.Biol., 9, 2014
4PX8
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BU of 4px8 by Molmil
Structure of P. vulgaris HigB toxin
分子名称: CHLORIDE ION, Killer protein
著者Schureck, M.A, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
登録日2014-03-22
公開日2015-10-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
4Q2U
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BU of 4q2u by Molmil
Crystal structure of the E. coli DinJ-YafQ toxin-antitoxin complex
分子名称: Antitoxin DinJ, SULFATE ION, mRNA interferase YafQ
著者Maehigashi, T, Ruangprasert, A, Dunham, C.M.
登録日2014-04-09
公開日2014-06-11
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mechanisms of Toxin Inhibition and Transcriptional Repression by Escherichia coli DinJ-YafQ.
J.Biol.Chem., 289, 2014
5UCT
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BU of 5uct by Molmil
Mycobacterium tuberculosis toxin MazF-mt6
分子名称: Endoribonuclease MazF3, SULFATE ION
著者Hoffer, E.H, Dunham, C.M.
登録日2016-12-22
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structure and function of Mycobacterium tuberculosis MazF-mt6 toxin provide insights into conserved features of MazF endonucleases.
J. Biol. Chem., 292, 2017
5VPP
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BU of 5vpp by Molmil
The 70S P-site tRNA SufA6 complex
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hong, S, Sunita, S, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
登録日2017-05-05
公開日2018-09-26
最終更新日2018-11-07
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Mechanism of tRNA-mediated +1 ribosomal frameshifting.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5VPO
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BU of 5vpo by Molmil
The 70S P-site ASL SufA6 complex
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hong, S, Sunita, S, Dunkle, J.A, Maehigashi, T, Dunham, C.M.
登録日2017-05-05
公開日2018-09-26
最終更新日2018-11-07
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Mechanism of tRNA-mediated +1 ribosomal frameshifting.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5UQ7
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BU of 5uq7 by Molmil
70S ribosome complex with dnaX mRNA stemloop and E-site tRNA ("in" conformation)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Zhang, Y, Hong, S, Skiniotis, G, Dunham, C.M.
登録日2017-02-07
公開日2018-03-07
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Alternative Mode of E-Site tRNA Binding in the Presence of a Downstream mRNA Stem Loop at the Entrance Channel.
Structure, 26, 2018
5UQ8
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BU of 5uq8 by Molmil
70S ribosome complex with dnaX mRNA stem-loop and E-site tRNA ("out" conformation)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Zhang, Y, Hong, S, Skiniotis, G, Dunham, C.M.
登録日2017-02-07
公開日2018-03-07
最終更新日2018-03-21
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Alternative Mode of E-Site tRNA Binding in the Presence of a Downstream mRNA Stem Loop at the Entrance Channel.
Structure, 26, 2018
4L71
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BU of 4l71 by Molmil
Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-A on the Ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Maehigashi, T, Dunkle, J.A, Dunham, C.M.
登録日2013-06-13
公開日2014-08-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.900001 Å)
主引用文献Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4L47
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BU of 4l47 by Molmil
Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-U on the Ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Maehigashi, T, Dunkle, J.A, Dunham, C.M.
登録日2013-06-07
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.220001 Å)
主引用文献Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014
4LFZ
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BU of 4lfz by Molmil
Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-U in the Absence of Paromomycin
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Maehigashi, T, Dunkle, J.A, Dunham, C.M.
登録日2013-06-27
公開日2014-08-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.92000055 Å)
主引用文献Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.
Proc.Natl.Acad.Sci.USA, 111, 2014

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