5VVJ
| Cas1-Cas2 bound to half-site intermediate | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (112-MER), ... | Authors: | Wright, A.V, Knott, G.J, Doxzen, K.W, Doudna, J.A. | Deposit date: | 2017-05-19 | Release date: | 2017-08-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.89 Å) | Cite: | Structures of the CRISPR genome integration complex. Science, 357, 2017
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5W1I
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5WFE
| Cas1-Cas2-IHF-DNA holo-complex | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ... | Authors: | Wright, A.V, Liu, J.J, Nogales, E, Doudna, J.A. | Deposit date: | 2017-07-11 | Release date: | 2017-08-02 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | Structures of the CRISPR genome integration complex. Science, 357, 2017
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5WLH
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2OIH
| Hepatitis Delta Virus gemonic ribozyme precursor with C75U mutation and bound to monovalent cation Tl+ | Descriptor: | HDV ribozyme, THALLIUM (I) ION, U1 small nuclear ribonucleoprotein A | Authors: | Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A. | Deposit date: | 2007-01-11 | Release date: | 2007-03-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural roles of monovalent cations in the HDV ribozyme. Structure, 15, 2007
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2OJ3
| Hepatitis Delta Virus ribozyme precursor structure, with C75U mutation, bound to Tl+ and cobalt hexammine (Co(NH3)63+) | Descriptor: | COBALT HEXAMMINE(III), HDV RIBOZYME, THALLIUM (I) ION, ... | Authors: | Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A. | Deposit date: | 2007-01-12 | Release date: | 2007-03-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural roles of monovalent cations in the HDV ribozyme. Structure, 15, 2007
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6MCC
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6MCB
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5K4C
| Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 2 | Descriptor: | Eukaryotic translation initiation factor 3 subunit D, GLYCEROL | Authors: | Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D. | Deposit date: | 2016-05-20 | Release date: | 2016-07-27 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.698 Å) | Cite: | eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation. Nature, 536, 2016
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5K4B
| Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 1 | Descriptor: | CHLORIDE ION, Eukaryotic translation initiation factor 3 subunit D | Authors: | Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D. | Deposit date: | 2016-05-20 | Release date: | 2016-07-27 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.399 Å) | Cite: | eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation. Nature, 536, 2016
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5K4D
| Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 3 | Descriptor: | Eukaryotic translation initiation factor 3 subunit D | Authors: | Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D. | Deposit date: | 2016-05-20 | Release date: | 2016-07-27 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation. Nature, 536, 2016
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7KFU
| Cas6-RT-Cas1--Cas2 complex | Descriptor: | Cas2, Cas6-RT-Cas1 | Authors: | Hoel, C.M, Wang, J.Y, Doudna, J.A, Brohawn, S.G. | Deposit date: | 2020-10-14 | Release date: | 2021-03-31 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex. Nat Commun, 12, 2021
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7KFT
| Partial Cas6-RT-Cas1--Cas2 complex | Descriptor: | Cas2, Cas6-RT-Cas1 | Authors: | Hoel, C.M, Wang, J.Y, Doudna, J.A, Brohawn, S.G. | Deposit date: | 2020-10-14 | Release date: | 2021-03-31 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex. Nat Commun, 12, 2021
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1SJ3
| Hepatitis Delta Virus Gemonic Ribozyme Precursor, with Mg2+ Bound | Descriptor: | MAGNESIUM ION, precursor form of the Hepatitis Delta virus ribozyme, small nuclear ribonucleoprotein A | Authors: | Ke, A, Zhou, K, Ding, F, Cate, J.H, Doudna, J.A. | Deposit date: | 2004-03-02 | Release date: | 2004-05-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A Conformational Switch controls hepatitis delta virus ribozyme
catalysis Nature, 429, 2004
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1SJF
| Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in Cobalt Hexammine solution | Descriptor: | COBALT HEXAMMINE(III), Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A | Authors: | Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A. | Deposit date: | 2004-03-03 | Release date: | 2004-05-18 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | A conformational switch controls hepatitis delta virus ribozyme catalysis. Nature, 429, 2004
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1SJ4
| Crystal structure of a C75U mutant Hepatitis Delta Virus ribozyme precursor, in Cu2+ solution | Descriptor: | precursor form of the Hepatitis Delta virus ribozyme, small nuclear ribonucleoprotein A | Authors: | Ke, A, Zhou, K, Ding, F, Cate, J.H, Doudna, J.A. | Deposit date: | 2004-03-02 | Release date: | 2004-05-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A Conformational Switch controls hepatitis delta virus ribozyme
catalysis Nature, 429, 2004
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6NY3
| CasX ternary complex with 30bp target DNA | Descriptor: | CasX, DNA Non-target strand, DNA target strand, ... | Authors: | Liu, J.J, Orlova, N, Nogales, E, Doudna, J.A. | Deposit date: | 2019-02-10 | Release date: | 2019-02-27 | Last modified: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | CasX enzymes comprise a distinct family of RNA-guided genome editors. Nature, 566, 2019
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6NY2
| CasX-gRNA-DNA(45bp) state I | Descriptor: | CasX, DNA Non-target strand, DNA target strand, ... | Authors: | Liu, J.J, Orlova, N, Nogales, E, Doudna, J.A. | Deposit date: | 2019-02-10 | Release date: | 2019-02-27 | Last modified: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | CasX enzymes comprise a distinct family of RNA-guided genome editors. Nature, 566, 2019
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6NY1
| CasX-gRNA-DNA(30bp) State II | Descriptor: | CasX, DNA Non-target strand, DNA target strand, ... | Authors: | Liu, J.J, Orlova, N, Nogales, E, Doudna, J.A. | Deposit date: | 2019-02-10 | Release date: | 2019-02-27 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | CasX enzymes comprise a distinct family of RNA-guided genome editors. Nature, 566, 2019
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6P7M
| Cryo-EM structure of LbCas12a-crRNA: AcrVA4 (1:2 complex) | Descriptor: | Cas12a, MAGNESIUM ION, anti-CRISPR VA4, ... | Authors: | Knott, G.J, Liu, J.J, Doudna, J.A. | Deposit date: | 2019-06-06 | Release date: | 2019-08-21 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a. Elife, 8, 2019
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6P7N
| Cryo-EM structure of LbCas12a-crRNA: AcrVA4 (2:2 complex) | Descriptor: | Cas12a, MAGNESIUM ION, anti-CRISPR VA4, ... | Authors: | Knott, G.J, Liu, J.J, Doudna, J.A. | Deposit date: | 2019-06-06 | Release date: | 2019-08-21 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a. Elife, 8, 2019
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1KH6
| Crystal Structure of an RNA Tertiary Domain Essential to HCV IRES-mediated Translation Initiation. | Descriptor: | JIIIabc | Authors: | Kieft, J.S, Zhou, K, Grech, A, Jubin, R, Doudna, J.A. | Deposit date: | 2001-11-29 | Release date: | 2002-04-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation. Nat.Struct.Biol., 9, 2002
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1KXK
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1L8V
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3T4B
| Crystal Structure of the HCV IRES pseudoknot domain | Descriptor: | HCV IRES pseudoknot domain plus crystallization module, NICKEL (II) ION | Authors: | Berry, K.E, Waghray, S, Mortimer, S.A, Bai, Y, Doudna, J.A. | Deposit date: | 2011-07-25 | Release date: | 2011-10-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.55 Å) | Cite: | Crystal structure of the HCV IRES central domain reveals strategy for start-codon positioning. Structure, 19, 2011
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