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PDB: 19 件
3QQD
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Human SOD1 H80R variant, P212121 crystal form
分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Schirf, V, Demeler, B, Carroll, M.C, Culotta, V.C, Hart, P.J.
登録日2011-02-15
公開日2011-03-09
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.653 Å)
主引用文献Disrupted zinc-binding sites in structures of pathogenic SOD1 variants D124V and H80R.
Biochemistry, 49, 2010
3H2P
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Human SOD1 D124V Variant
分子名称: ACETYL GROUP, MALONATE ION, Superoxide dismutase [Cu-Zn], ...
著者Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Carroll, M.C, Culotta, V.C, Hart, P.J.
登録日2009-04-14
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding and Compromised Post-translational Modification by the Copper Chaperone CCS
To be Published
3CQP
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Human SOD1 G85R Variant, Structure I
分子名称: COPPER (II) ION, MALONATE ION, Superoxide dismutase [Cu-Zn], ...
著者Cao, X, Antonyuk, S, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Valentine, J.S, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Hasnain, S.S, Hart, P.J.
登録日2008-04-03
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
1HL5
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The Structure of Holo Type Human Cu, Zn Superoxide Dismutase
分子名称: CALCIUM ION, COPPER (II) ION, SUPEROXIDE DISMUTASE, ...
著者Strange, R.W, Antonyuk, S, Hough, M.A, Doucette, P, Rodriguez, J, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S.
登録日2003-03-13
公開日2003-05-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Structure of Holo and Metal-Deficient Wild-Type Human Cu, Zn Superoxide Dismutase and its Relevance to Familial Amyotrophic Lateral Sclerosis
J.Mol.Biol., 328, 2003
1HL4
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The Structure of Apo Type Human Cu, Zn Superoxide Dismutase
分子名称: SUPEROXIDE DISMUTASE, ZINC ION
著者Strange, R.W, Antonyuk, S, Hough, M.A, Doucette, P, Rodriguez, J, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S.
登録日2003-03-13
公開日2003-05-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献The Structure of Holo and Metal-Deficient Wild-Type Human Cu, Zn Superoxide Dismutase and its Relevance to Familial Amyotrophic Lateral Sclerosis
J.Mol.Biol., 328, 2003
3CQQ
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Human SOD1 G85R Variant, Structure II
分子名称: ACETYL GROUP, Superoxide dismutase [Cu-Zn], ZINC ION
著者Cao, X, Antonyuk, S, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Valentine, J.S, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Hasnain, S.S, Hart, P.J.
登録日2008-04-03
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
3H2Q
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Human SOD1 H80R variant, P21 crystal form
分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Carroll, M.C, Culotta, V.C, Hart, P.J.
登録日2009-04-14
公開日2010-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding and Compromised Post-translational Modification by the Copper Chaperone CCS
To be Published
2VR7
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Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.58 A resolution
分子名称: COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Antonyuk, S, Cao, X, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Selverstone Valentine, J, Hasnain, S.S, Hart, P.J.
登録日2008-03-28
公開日2008-04-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structures of the G85R Variant of Sod1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
2VR8
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Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.36 A resolution
分子名称: COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Antonyuk, S, Cao, X, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Selverstone Valentine, J, Hasnain, S.S, Hart, P.J.
登録日2008-03-28
公開日2008-04-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Structures of the G85R Variant of Sod1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
2VR6
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Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.3 A resolution
分子名称: COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Antonyuk, S, Cao, X, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Selverstone Valentine, J, Hasnain, S.S, Hart, P.J.
登録日2008-03-28
公開日2008-04-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structures of the G85R Variant of Sod1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
1UXM
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A4V mutant of human SOD1
分子名称: COPPER (II) ION, SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION
著者Hough, M.A, Grossmann, J.G, Antonyuk, S.V, Strange, R.W, Doucette, P.A, Rodriguez, J.A, Whitson, L.J, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S.
登録日2004-02-26
公開日2004-03-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Dimer Destabilization in Superoxide Dismutase May Result in Disease-Causing Properties: Structures of Motor Neuron Disease Mutants
Proc.Natl.Acad.Sci.USA, 101, 2004
1UXL
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I113T mutant of human SOD1
分子名称: COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Hough, M.A, Grossmann, J.G, Antonyuk, S.V, Strange, R.W, Doucette, P.A, Rodriguez, J.A, Whitson, L.J, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S.
登録日2004-02-25
公開日2004-03-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Dimer Destabilization in Superoxide Dismutase May Result in Disease-Causing Properties: Structures of Motor Neuron Disease Mutants
Proc.Natl.Acad.Sci.USA, 101, 2004
2C9V
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Atomic resolution structure of Cu-Zn Human Superoxide dismutase
分子名称: COPPER (II) ION, SODIUM ION, SULFATE ION, ...
著者Strange, R.W, Antonyuk, S.V, Hough, M.A, Doucette, P.A, Valentine, J.S, Hasnain, S.S.
登録日2005-12-14
公開日2005-12-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu-Zn, Zn-Zn and as-Isolated Wild-Type Enzymes.
J.Mol.Biol., 356, 2006
2C9U
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1.24 Angstroms resolution structure of as-isolated Cu-Zn Human Superoxide dismutase
分子名称: ACETATE ION, COPPER (II) ION, SULFATE ION, ...
著者Strange, R.W, Antonyuk, S.V, Hough, M.A, Doucette, P.A, Valentine S, J.S, Hasnain, S.
登録日2005-12-14
公開日2005-12-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu-Zn, Zn-Zn and as-Isolated Wild-Type Enzymes.
J.Mol.Biol., 356, 2006
2C9S
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1.24 Angstroms resolution structure of Zn-Zn Human Superoxide dismutase
分子名称: ACETATE ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Strange, R.W, Antonyuk, S.V, Hough, M.A, Doucette, P.A, Valentine S, J.S, Hasnain, S.
登録日2005-12-14
公開日2005-12-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu-Zn, Zn-Zn and as-Isolated Wild-Type Enzymes.
J.Mol.Biol., 356, 2006
1OEZ
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Zn His46Arg mutant of Human Cu, Zn Superoxide Dismutase
分子名称: SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION
著者Strange, R.W, Antonyuk, S, Hough, M.A, Doucette, P, Rodriguez, J, Elam, J.S, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S.
登録日2003-04-02
公開日2003-05-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Amyloid-Like Filaments and Water-Filled Nanotubes Formed by Sod1 Mutant Proteins Linked to Familial Als
Nat.Struct.Biol., 10, 2003
1OZU
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Crystal Structure of Familial ALS Mutant S134N of human Cu,Zn Superoxide Dismutase (CuZnSOD) to 1.3A resolution
分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Elam, J.S, Taylor, A.B, Strange, R, Antonyuk, S, Doucette, P.A, Rodriguez, J.A, Hasnain, S.S, Hayward, L.J, Valentine, J.S, Yeates, T.O, Hart, P.J.
登録日2003-04-09
公開日2003-05-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Amyloid-like Filaments and Water-filled Nanotubes Formed by SOD1 Mutant Proteins Linked to Familial ALS
Nat.Struct.Biol., 10, 2003
1OZT
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Crystal Structure of apo-H46R Familial ALS Mutant human Cu,Zn Superoxide Dismutase (CuZnSOD) to 2.5A resolution
分子名称: Superoxide dismutase [Cu-Zn]
著者Elam, J.S, Taylor, A.B, Strange, R, Antonyuk, S, Doucette, P.A, Rodriguez, J.A, Hasnain, S.S, Hayward, L.J, Valentine, J.S, Yeates, T.O, Hart, P.J.
登録日2003-04-09
公開日2003-05-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Amyloid-like Filaments and Water-filled Nanotubes Formed by SOD1 Mutant Proteins Linked to Familial ALS
Nat.Struct.Biol., 10, 2003
1P1V
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Crystal Structure of FALS-associated human Copper-Zinc Superoxide Dismutase (CuZnSOD) Mutant D125H to 1.4A
分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Elam, J.S, Malek, K, Rodriguez, J.A, Doucette, P.A, Taylor, A.B, Hayward, L.J, Cabelli, D.E, Valentine, J.S, Hart, P.J.
登録日2003-04-14
公開日2003-08-26
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献An Alternative Mechanism of Bicarbonate-mediated Peroxidation by Copper-Zinc Superoxide Dismutase: RATES ENHANCED VIA PROPOSED ENZYME-ASSOCIATED PEROXYCARBONATE INTERMEDIATE
J.Biol.Chem., 278, 2003

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