7U4Q
 
 | |
7TUA
 | |
7TX9
 | | Human Synaptotagmin-1 C2B Y312F Ca2+ bound | | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Dominguez, M.J, Karmakar, S, Fuson, K.L, Sutton, R.B. | | 登録日 | 2022-02-08 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | | 主引用文献 | Human Synaptotagmin-1 C2B Y312F Ca2+ bound
To Be Published
|
|
6U41
 | | 1.7 angstrom structure of a pathogenic human Syt 1 C2B (D304G) | | 分子名称: | SULFATE ION, Synaptotagmin-1 | | 著者 | Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B. | | 登録日 | 2019-08-22 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
|
|
6U4U
 | | 1.3 A structure of a pathogenic human Syt 1 C2B (I368T) | | 分子名称: | SULFATE ION, Synaptotagmin-1 | | 著者 | Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B. | | 登録日 | 2019-08-26 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
|
|
6U4W
 | | 1.4 A structure of a pathogenic human Syt 1 C2B (D366E) | | 分子名称: | SULFATE ION, Synaptotagmin-1 | | 著者 | Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B. | | 登録日 | 2019-08-26 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
|
|
6TZ3
 | | Crystal Structure of Human Synaptotagmin 1 C2B without Ca2+ | | 分子名称: | SULFATE ION, Synaptotagmin-1 | | 著者 | Dominguez, M.J, Karmakar, S, Meyer, A.G, Sutton, R.B. | | 登録日 | 2019-08-09 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | | 主引用文献 | Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
|
|
6UIO
 | | Crystal structure of mouse CRES (Cystatin-Related Epididymal Spermatogenic) | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Cystatin-8, ... | | 著者 | Dominguez, M.J, Cornwall, G.A, Hewetson, A, Sutton, R.B. | | 登録日 | 2019-10-01 | | 公開日 | 2020-07-01 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Maturation of the functional mouse CRES amyloid from globular form.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
1QY7
 | | The structure of the PII protein from the cyanobacteria Synechococcus sp. PCC 7942 | | 分子名称: | NICKEL (II) ION, Nitrogen regulatory protein P-II, SULFATE ION | | 著者 | Xu, Y, Carr, P.D, Clancy, P, Garcia-Dominguez, M, Forchhammer, K, Florencio, F, Tandeau de Marsac, N, Vasudevan, S.G, Ollis, D.L. | | 登録日 | 2003-09-09 | | 公開日 | 2003-09-23 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structures of the PII proteins from the cyanobacteria Synechococcus sp. PCC 7942 and Synechocystis sp. PCC 6803.
Acta Crystallogr.,Sect.D, 59, 2003
|
|
1UL3
 | | Crystal Structure of PII from Synechocystis sp. PCC 6803 | | 分子名称: | CALCIUM ION, GLYCEROL, Nitrogen regulatory protein P-II | | 著者 | Xu, Y, Carr, P.D, Clancy, P, Garcia-Dominguez, M, Forchhammer, K, Florencio, F, Tandeau de Marsac, N, Vasudevan, S.G, Ollis, D.L. | | 登録日 | 2003-09-09 | | 公開日 | 2003-12-16 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structures of the PII proteins from the cyanobacteria Synechococcus sp. PCC 7942 and Synechocystis sp. PCC 6803.
Acta Crystallogr.,Sect.D, 59, 2003
|
|
8FAM
 | | Edited Octopus bimaculoides Synaptotagmin 1 C2A (I248V) at room temperature | | 分子名称: | Synaptotagmin | | 著者 | McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.J, Sutton, R.B. | | 登録日 | 2022-11-28 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Temperature-dependent RNA editing in octopus extensively recodes the neural proteome.
Cell, 186, 2023
|
|
8FAF
 | | Unedited Octopus bimaculoides Synaptotagmin 1 C2A at room temperature | | 分子名称: | Synaptotagmin | | 著者 | McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.C, Sutton, R.B. | | 登録日 | 2022-11-26 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Temperature-dependent RNA editing in octopus extensively recodes the neural proteome.
Cell, 186, 2023
|
|
4XZH
 | | Crystal structure of human Aldose Reductase complexed with NADP+ and JF0048 | | 分子名称: | Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [3-(4-chloro-3-nitrobenzyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl]acetic acid | | 著者 | Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Dominguez, M, de Lera, A.R, Farres, J, Pares, X, Podjarny, A. | | 登録日 | 2015-02-04 | | 公開日 | 2015-11-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10.
Chemmedchem, 10, 2015
|
|
4XZI
 | | Crystal structure of human Aldose Reductase complexed with NADP+ and JF0049 | | 分子名称: | Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [2,4-dioxo-3-(2,3,4,5-tetrabromo-6-methoxybenzyl)-3,4-dihydropyrimidin-1(2H)-yl]acetic acid | | 著者 | Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Dominguez, M, de Lera, A.R, Farres, J, Pares, X, Podjarny, A. | | 登録日 | 2015-02-04 | | 公開日 | 2015-11-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10.
Chemmedchem, 10, 2015
|
|
4XZL
 | | Crystal structure of human AKR1B10 complexed with NADP+ and JF0049 | | 分子名称: | 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Dominguez, M, de Lera, A.R, Farres, J, Pares, X, Podjarny, A. | | 登録日 | 2015-02-04 | | 公開日 | 2015-11-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10.
Chemmedchem, 10, 2015
|
|
1ZUA
 | | Crystal Structure Of AKR1B10 Complexed With NADP+ And Tolrestat | | 分子名称: | Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TOLRESTAT | | 著者 | Gallego, O, Ruiz, F.X, Ardevol, A, Dominguez, M, Alvarez, R, de Lera, A.R, Rovira, C, Farres, J, Fita, I, Pares, X. | | 登録日 | 2005-05-30 | | 公開日 | 2006-11-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Structural basis for the high all-trans-retinaldehyde reductase activity of the tumor marker AKR1B10.
Proc.Natl.Acad.Sci.USA, 104, 2007
|
|
5M2F
 | | Crystal structure of human AKR1B10 complexed with NADP+ and the synthetic retinoid UVI2008 | | 分子名称: | 1,2-ETHANEDIOL, 3-bromo-4-[(1E)-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]benzoic acid, Aldo-keto reductase family 1 member B10, ... | | 著者 | Ruiz, F.X, Cousido-Siah, A, Mitschler, A, Porte, S, Alvarez, S, Dominguez, M, Alvarez, R, de Lera, A.R, Pares, X, Farres, J, Podjarny, A. | | 登録日 | 2016-10-12 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.503 Å) | | 主引用文献 | Structural basis for the inhibition of AKR1B10 by the C3 brominated TTNPB derivative UVI2008.
Chem. Biol. Interact., 276, 2017
|
|
