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PDB: 340 件

3WA5
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Crystal Structure of type VI peptidoglycan muramidase effector Tse3 in complex with its cognate immunity protein Tsi3
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Tse3-specific immunity protein, ...
著者Ding, J, Wang, T, Liu, W, Wang, D.C.
登録日2013-04-26
公開日2013-10-02
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Complex structure of type VI peptidoglycan muramidase effector and a cognate immunity protein.
Acta Crystallogr.,Sect.D, 69, 2013
5Z2C
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Crystal structure of ALPK-1 N-terminal domain in complex with ADP-heptose
分子名称: Alpha-protein kinase 1, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4S,5S,6R)-6-[(1S)-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl] hydrogen phosphate
著者Ding, J, She, Y, Shao, F.
登録日2018-01-02
公開日2018-08-22
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.594 Å)
主引用文献Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose.
Nature, 561, 2018
3AJM
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BU of 3ajm by Molmil
Crystal structure of programmed cell death 10 in complex with inositol 1,3,4,5-tetrakisphosphate
分子名称: INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, Programmed cell death protein 10
著者Ding, J, Wang, D.C.
登録日2010-06-09
公開日2010-06-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of human programmed cell death 10 complexed with inositol-(1,3,4,5)-tetrakisphosphate: a novel adaptor protein involved in human cerebral cavernous malformation.
Biochem.Biophys.Res.Commun., 399, 2010
4YKC
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BU of 4ykc by Molmil
Crystal structure of cerebral cavernous malformation 2 C-terminal adaptor domain
分子名称: Malcavernin
著者Ding, J, Wang, X, Wang, D.C.
登録日2015-03-04
公開日2015-06-03
最終更新日2015-06-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3
Structure, 23, 2015
1AVP
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BU of 1avp by Molmil
STRUCTURE OF HUMAN ADENOVIRUS 2 PROTEINASE WITH ITS 11 AMINO ACID COFACTOR
分子名称: ADENOVIRAL PROTEINASE
著者Ding, J, Mcgrath, W.J, Sweet, R.M, Mangel, W.F.
登録日1996-04-04
公開日1997-11-19
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the human adenovirus proteinase with its 11 amino acid cofactor.
EMBO J., 15, 1996
4YL6
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Crystal structure of truncated cerebral cavernous malformation 2 C-terminal adaptor domain in complex with an internal helix of mitogen-activated protein kinase kinase kinase 3
分子名称: Malcavernin, Mitogen-activated protein kinase kinase kinase 3
著者Ding, J, Wang, X, Wang, D.C.
登録日2015-03-05
公開日2015-06-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3
Structure, 23, 2015
4YKD
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BU of 4ykd by Molmil
Crystal structure of truncated cerebral cavernous malformation 2 C-terminal adaptor domain
分子名称: Malcavernin
著者Ding, J, Wang, X, Wang, D.C.
登録日2015-03-04
公開日2015-06-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.932 Å)
主引用文献Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3
Structure, 23, 2015
3WLC
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BU of 3wlc by Molmil
Crystal structure of dimeric GCaMP6m
分子名称: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ...
著者Ding, J, Luo, A.F, Hu, L.Y, Wang, D.C, Shao, F.
登録日2013-11-08
公開日2014-01-22
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural basis of the ultrasensitive calcium indicator GCaMP6.
Sci China Life Sci, 57, 2014
3WLD
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BU of 3wld by Molmil
Crystal structure of monomeric GCaMP6m
分子名称: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ...
著者Ding, J, Luo, A.F, Hu, L.Y, Wang, D.C, Shao, F.
登録日2013-11-08
公開日2014-01-22
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of the ultrasensitive calcium indicator GCaMP6.
Sci China Life Sci, 57, 2014
5B5R
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BU of 5b5r by Molmil
Crystal structure of GSDMA3
分子名称: Gasdermin-A3
著者Ding, J, Shao, F.
登録日2016-05-14
公開日2016-06-15
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Pore-forming activity and structural autoinhibition of the gasdermin family.
Nature, 535, 2016
6ACI
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BU of 6aci by Molmil
Crystal structure of EPEC effector NleB in complex with FADD death domain
分子名称: FAS-associated death domain protein, MANGANESE (II) ION, T3SS secreted effector NleB homolog, ...
著者Ding, J, Shao, F.
登録日2018-07-26
公開日2019-05-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.
Mol.Cell, 74, 2019
6AC0
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Crystal structure of TRADD death domain GlcNAcylated by EPEC effector NleB
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor receptor type 1-associated DEATH domain protein
著者Ding, J, Shao, F.
登録日2018-07-24
公開日2019-05-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.449 Å)
主引用文献Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.
Mol.Cell, 74, 2019
6KMV
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BU of 6kmv by Molmil
caspase-11 C254A P22/P10 in complex with mouse GSDMD-C domain
分子名称: Caspase-4, Gasdermin-D
著者Ding, J, Sun, Q.
登録日2019-08-01
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
6KMZ
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caspase-4 P22/P10 C258A in complex with human GSDMD-C domain
分子名称: Caspase-4, Gasdermin-D
著者Ding, J, Sun, Q.
登録日2019-08-01
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.61 Å)
主引用文献Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
6KMU
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BU of 6kmu by Molmil
P22/P10 complex of caspase-11 mutant C254A
分子名称: Caspase-4
著者Ding, J, Sun, Q.
登録日2019-08-01
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
7DN8
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BU of 7dn8 by Molmil
Crystal structure of Salmonella effector SopF in complex with ARF1
分子名称: ADP-ribosylation factor 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Ding, J, Shao, F.
登録日2020-12-09
公開日2021-12-15
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.6084 Å)
主引用文献ARF GTPases activate Salmonella effector SopF to ADP-ribosylate host V-ATPase and inhibit endomembrane damage-induced autophagy.
Nat.Struct.Mol.Biol., 29, 2022
7DN9
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BU of 7dn9 by Molmil
Crystal structure of Salmonella effector in complex with NAD and host co-factor ARF1
分子名称: ADP-ribosylation factor 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Ding, J, Shao, F.
登録日2020-12-09
公開日2021-12-15
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献ARF GTPases activate Salmonella effector SopF to ADP-ribosylate host V-ATPase and inhibit endomembrane damage-induced autophagy.
Nat.Struct.Mol.Biol., 29, 2022
6KN1
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BU of 6kn1 by Molmil
P20/P12 of caspase-11 mutant C254A
分子名称: Caspase-4
著者Ding, J, Sun, Q.
登録日2019-08-02
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
6KN0
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BU of 6kn0 by Molmil
caspase-1 P20/P10 C285A in complex with human GSDMD-C domain
分子名称: Caspase-1, Gasdermin-D
著者Ding, J, Sun, Q.
登録日2019-08-02
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.793 Å)
主引用文献Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
6KMT
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BU of 6kmt by Molmil
P32 of caspase-11 mutant C254A
分子名称: Caspase-4
著者Ding, J, Sun, Q.
登録日2019-08-01
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
7WZS
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BU of 7wzs by Molmil
Crystal structure of Chromobacterium violaceum effector CopC in complex with host calmodulin and caspase-7
分子名称: Calmodulin-1, Caspase-7, CopC
著者Ding, J.
登録日2022-02-19
公開日2022-05-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Calmodulin Binding Activates Chromobacterium CopC Effector to ADP-Riboxanate Host Apoptotic Caspases.
Mbio, 13, 2022
1WAV
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BU of 1wav by Molmil
CRYSTAL STRUCTURE OF FORM B MONOCLINIC CRYSTAL OF INSULIN
分子名称: INSULIN, PHENOL, ZINC ION
著者Liang, D.-C, Ding, J.-H, Chang, W.-R, Wan, Z.-L.
登録日1996-02-28
公開日1997-02-28
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular replacement study on form-B monoclinic crystal of insulin.
Sci.China, Ser.C: Life Sci., 39, 1996
8HQN
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BU of 8hqn by Molmil
Activation mechanism of GPR132 by 9(S)-HODE
分子名称: (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Wang, J.L, Ding, J.H, Sun, J.P, Yu, X.
登録日2022-12-13
公開日2023-10-11
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Nat Metab, 5, 2023
8HVI
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Activation mechanism of GPR132 by compound NOX-6-7
分子名称: 3-methyl-5-[(4-oxidanylidene-4-phenyl-butanoyl)amino]-1-benzofuran-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Wang, J.L, Ding, J.H, Sun, J.P, Yu, X.
登録日2022-12-26
公開日2023-10-11
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Nat Metab, 5, 2023
8HQM
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BU of 8hqm by Molmil
Activation mechanism of GPR132 by NPGLY
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Wang, J.L, Ding, J.H, Sun, J.P, Yu, X.
登録日2022-12-13
公開日2023-10-11
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Nat Metab, 5, 2023

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