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PDB: 48 件

5A5U
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Structure of mammalian eIF3 in the context of the 43S preinitiation complex
分子名称: EUKARYOTIC INITIATION FACTOR 3, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I
著者des-Georges, A, Dhote, V, Kuhn, L, Hellen, C.U.T, Pestova, T.V, Frank, J, Hashem, Y.
登録日2015-06-21
公開日2015-09-09
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Structure of Mammalian Eif3 in the Context of the 43S Preinitiation Complex.
Nature, 525, 2015
5A5T
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Structure of mammalian eIF3 in the context of the 43S preinitiation complex
分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E, ...
著者des-Georges, A, Dhote, V, Kuhn, L, Hellen, C.U.T, Pestova, T.V, Frank, J, Hashem, Y.
登録日2015-06-21
公開日2015-09-09
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Structure of Mammalian Eif3 in the Context of the 43S Preinitiation Complex.
Nature, 525, 2015
3J5Y
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BU of 3j5y by Molmil
Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP
分子名称: 5'-R(*AP*UP*UP*GP*UP*AP*AP*AP*AP*A)-3', Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1, ...
著者des Georges, A, Hashem, Y, Unbehaun, A, Grassucci, R.A, Taylor, D, Hellen, C.U.T, Pestova, T.V, Frank, J.
登録日2013-11-21
公開日2013-12-25
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (9.7 Å)
主引用文献Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP.
Nucleic Acids Res., 42, 2014
4V8M
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BU of 4v8m by Molmil
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome
分子名称: 18S RRNA OF THE SMALL RIBOSOMAL SUBUNIT, 40S RIBOSOMAL PROTEIN S10, PUTATIVE, ...
著者Hashem, Y, des Georges, A, Fu, J, Buss, S.N, Jossinet, F, Jobe, A, Zhang, Q, Liao, H.Y, Grassucci, R.A, Bajaj, C, Westhof, E, Madison-Antenucci, S, Frank, J.
登録日2012-12-09
公開日2014-07-09
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (5.57 Å)
主引用文献High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome.
Nature, 494, 2013
6PV6
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BU of 6pv6 by Molmil
Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
著者Dashti, A, des Georges, A, Frank, J, Ourmazd, A.
登録日2019-07-19
公開日2020-08-12
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Retrieving functional pathways of biomolecules from single-particle snapshots.
Nat Commun, 11, 2020
7N4T
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BU of 7n4t by Molmil
Low conductance mechanosensitive channel YnaI
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Low conductance mechanosensitive channel YnaI
著者Catalano, C, Ben-Hail, D, Qiu, W, des Georges, A, Guo, Y.
登録日2021-06-04
公開日2022-04-20
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Cryo-EM Structure of Mechanosensitive Channel YnaI Using SMA2000: Challenges and Opportunities.
Membranes (Basel), 11, 2021
7RAZ
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BU of 7raz by Molmil
Small conductance mechanosensitive channel MscS
分子名称: PHOSPHATIDYLETHANOLAMINE, Small-conductance mechanosensitive channel
著者Catalano, C, Ben-Hail, D, Qiu, W, des Georges, A, Guo, Y.
登録日2021-07-05
公開日2022-07-13
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Small conductance mechanosensitive channel MscS
To Be Published
7RR7
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BU of 7rr7 by Molmil
Multidrug efflux pump subunit AcrB
分子名称: DODECANE, Multidrug efflux pump subunit AcrB, PHOSPHATIDYLETHANOLAMINE
著者Trinh, T.K.H, Cabezas, A, Catalano, C, Qiu, W, des Georges, A, Guo, Y.
登録日2021-08-09
公開日2022-08-17
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献pH-tunable membrane-active polymers, NCMNP2a- x , and their potential membrane protein applications.
Chem Sci, 14, 2023
7RR6
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BU of 7rr6 by Molmil
Multidrug efflux pump subunit AcrB
分子名称: DODECANE, Multidrug efflux pump subunit AcrB, PHOSPHATIDYLETHANOLAMINE
著者Trinh, T.K.H, Cabezas, A, Catalano, C, Qiu, W, des Georges, A, Guo, Y.
登録日2021-08-09
公開日2022-08-17
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献pH-tunable membrane-active polymers, NCMNP2a- x , and their potential membrane protein applications.
Chem Sci, 14, 2023
7RR8
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BU of 7rr8 by Molmil
Multidrug efflux pump subunit AcrB
分子名称: DODECANE, Multidrug efflux pump subunit AcrB, PHOSPHATIDYLETHANOLAMINE
著者Trinh, T.K.H, Cabezas, A, Catalano, C, Qiu, W, des Georges, A, Guo, Y.
登録日2021-08-09
公開日2022-08-17
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献pH-tunable membrane-active polymers, NCMNP2a- x , and their potential membrane protein applications.
Chem Sci, 14, 2023
6UWT
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BU of 6uwt by Molmil
Clostridium difficile binary toxin translocase CDTb tetradecamer in symmetric conformation
分子名称: ADP-ribosyltransferase binding component, CALCIUM ION
著者Xu, X, Pozharski, E, des Georges, A.
登録日2019-11-05
公開日2020-01-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UWR
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BU of 6uwr by Molmil
Clostridium difficile binary toxin translocase CDTb in asymmetric tetradecamer conformation
分子名称: ADP-ribosyltransferase binding component, CALCIUM ION
著者Xu, X, Pozharski, E, des Georges, A.
登録日2019-11-05
公開日2020-01-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly.
Proc.Natl.Acad.Sci.USA, 117, 2020
6GSR
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BU of 6gsr by Molmil
Single Particle Cryo-EM map of human Transferrin receptor 1 - H-Ferritin complex at 5.5 Angstrom resolution.
分子名称: Ferritin heavy chain, Transferrin receptor protein 1
著者Testi, C, Montemiglio, L.C, Vallone, B, Des Georges, A, Boffi, A, Mancia, F, Baiocco, P.
登録日2018-06-15
公開日2019-03-27
最終更新日2019-05-08
実験手法ELECTRON MICROSCOPY (5.5 Å)
主引用文献Cryo-EM structure of the human ferritin-transferrin receptor 1 complex.
Nat Commun, 10, 2019
7ZQS
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BU of 7zqs by Molmil
Cryo-EM Structure of Human Transferrin Receptor 1 bound to DNA Aptamer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (30-MER), ...
著者Bansia, H, Wang, T, Gutierrez, D, des Georges, A.
登録日2022-05-02
公開日2022-08-17
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.54 Å)
主引用文献Discovery of a Transferrin Receptor 1-Binding Aptamer and Its Application in Cancer Cell Depletion for Adoptive T-Cell Therapy Manufacturing.
J.Am.Chem.Soc., 144, 2022
6H5I
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BU of 6h5i by Molmil
Single Particle Cryo-EM map of human Transferrin receptor 1 - H-Ferritin complex.
分子名称: Ferritin heavy chain, Transferrin receptor protein 1
著者Testi, C, Montemiglio, L.C, Vallone, B, Des Georges, A, Boffi, A, Mancia, F, Baiocco, P, Savino, C.
登録日2018-07-24
公開日2019-03-27
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structure of the human ferritin-transferrin receptor 1 complex.
Nat Commun, 10, 2019
6NI2
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BU of 6ni2 by Molmil
Stabilized beta-arrestin 1-V2T subcomplex of a GPCR-G protein-beta-arrestin mega-complex
分子名称: Beta-arrestin-1, Fab30 Heavy Chain, Fab30 Light Chain, ...
著者Nguyen, A.H, Thomsen, A.R.B, Cahill, T.J, des Georges, A, Lefkowitz, R.J.
登録日2018-12-26
公開日2019-11-20
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex.
Nat.Struct.Mol.Biol., 26, 2019
6NI3
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BU of 6ni3 by Molmil
B2V2R-Gs protein subcomplex of a GPCR-G protein-beta-arrestin mega-complex
分子名称: 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Endolysin,Beta-2 adrenergic receptor chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Nguyen, A.H, Thomsen, A.R.B, Cahill, T.J, des Georges, A, Lefkowitz, R.J.
登録日2018-12-26
公開日2019-11-20
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex.
Nat.Struct.Mol.Biol., 26, 2019
6BBM
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BU of 6bbm by Molmil
Mechanisms of Opening and Closing of the Bacterial Replicative Helicase: The DnaB Helicase and Lambda P Helicase Loader Complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Replication protein P, Replicative DNA helicase
著者Chase, J, Catalano, A, Noble, A.J, Eng, E.T, Olinares, P.D.B, Molloy, K, Pakotiprapha, D, Samuels, M, Chain, B, des Georges, A, Jeruzalmi, D.
登録日2017-10-18
公開日2019-03-06
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Mechanisms of opening and closing of the bacterial replicative helicase.
Elife, 7, 2018
7JMF
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BU of 7jmf by Molmil
Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 42 - State 6 (S6)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ...
著者Dashti, A, des Georges, A, Frank, J, Ourmazd, A.
登録日2020-07-31
公開日2020-08-12
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Retrieving functional pathways of biomolecules from single-particle snapshots.
Nat Commun, 11, 2020
7JMH
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BU of 7jmh by Molmil
Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 35 - State 4 (S4)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ...
著者Dashti, A, des Georges, A, Frank, J, Ourmazd, A.
登録日2020-07-31
公開日2020-08-12
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Retrieving functional pathways of biomolecules from single-particle snapshots.
Nat Commun, 11, 2020
7JMI
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BU of 7jmi by Molmil
Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 29 - State 3 (S3)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ...
著者Dashti, A, des Georges, A, Frank, J, Ourmazd, A.
登録日2020-07-31
公開日2020-08-12
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Retrieving functional pathways of biomolecules from single-particle snapshots.
Nat Commun, 11, 2020
7JMJ
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BU of 7jmj by Molmil
Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 37 - State 5 (S5)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ...
著者Dashti, A, des Georges, A, Frank, J, Ourmazd, A.
登録日2020-07-31
公開日2020-08-12
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Retrieving functional pathways of biomolecules from single-particle snapshots.
Nat Commun, 11, 2020
7JMG
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BU of 7jmg by Molmil
Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 22 - State 2 (S2)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ...
著者Dashti, A, des Georges, A, Frank, J, Ourmazd, A.
登録日2020-07-31
公開日2020-08-12
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Retrieving functional pathways of biomolecules from single-particle snapshots.
Nat Commun, 11, 2020
5TB1
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BU of 5tb1 by Molmil
Structure of rabbit RyR1 (EGTA-only dataset, class 1)
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION
著者Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J.
登録日2016-09-10
公開日2016-10-12
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural Basis for Gating and Activation of RyR1.
Cell, 167, 2016
5T9R
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BU of 5t9r by Molmil
Structure of rabbit RyR1 (Ca2+-only dataset, class 3)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
著者Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J.
登録日2016-09-09
公開日2016-10-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Structural Basis for Gating and Activation of RyR1.
Cell, 167, 2016

 

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