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PDB: 130 results

3FHE
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BU of 3fhe by Molmil
Leukotriene A4 Hydrolase complexed with inhibitor N-[3-(4-benzylphenoxy)propyl]-N-methyl-beta-alanine.
Descriptor: ACETATE ION, IMIDAZOLE, Leukotriene A-4 hydrolase, ...
Authors:Mamat, B, Davies, D.R.
Deposit date:2008-12-09
Release date:2010-01-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis.
J.Med.Chem., 53, 2010
7MFC
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BU of 7mfc by Molmil
Crystal structure of CSF1R in complex with vimseltinib
Descriptor: Macrophage colony-stimulating factor 1 receptor, Vimseltinib
Authors:Abendroth, J, Davies, D.R, Atkins, K.
Deposit date:2021-04-08
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Vimseltinib: A Precision CSF1R Therapy for Tenosynovial Giant Cell Tumors and Diseases Promoted by Macrophages.
Mol.Cancer Ther., 20, 2021
2TGI
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BU of 2tgi by Molmil
CRYSTAL STRUCTURE OF TRANSFORMING GROWTH FACTOR-BETA2: AN UNUSUAL FOLD FOR THE SUPERFAMILY
Descriptor: TRANSFORMING GROWTH FACTOR ,BETA 2
Authors:Daopin, S, Davies, D.R.
Deposit date:1993-10-20
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily.
Science, 257, 1992
2TRS
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BU of 2trs by Molmil
CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES
Descriptor: INDOLE-3-PROPANOL PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE, ...
Authors:Rhee, S, Parris, K.D, Hyde, C.C, Ahmed, S.A, Miles, E.W, Davies, D.R.
Deposit date:1997-01-07
Release date:1997-04-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes.
Biochemistry, 36, 1997
2TSY
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BU of 2tsy by Molmil
CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES
Descriptor: SN-GLYCEROL-3-PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE, ...
Authors:Rhee, S, Parris, K.D, Hyde, C.C, Ahmed, S.A, Miles, E.W, Davies, D.R.
Deposit date:1997-01-03
Release date:1997-04-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes.
Biochemistry, 36, 1997
2TYS
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BU of 2tys by Molmil
CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES
Descriptor: SODIUM ION, TRYPTOPHAN SYNTHASE, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-L-TRYPTOPHANE
Authors:Rhee, S, Parris, K.D, Hyde, C.C, Ahmed, S.A, Miles, E.W, Davies, D.R.
Deposit date:1997-01-08
Release date:1997-04-01
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes.
Biochemistry, 36, 1997
6MBQ
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BU of 6mbq by Molmil
Crystal structure of Mg-free wild-type KRAS (2-166) bound to GMPPNP in the state 1 conformation
Descriptor: 1,2-ETHANEDIOL, GTPase KRas, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Dharmaiah, S, Davies, D.R, Abendroth, J, Gillette, W.G, Stephen, A.G, Simanshu, D.K.
Deposit date:2018-08-30
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structures of N-terminally processed KRAS provide insight into the role of N-acetylation.
Sci Rep, 9, 2019
1DHS
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BU of 1dhs by Molmil
CRYSTAL STRUCTURE OF THE NAD COMPLEX OF HUMAN DEOXYHYPUSINE SYNTHASE
Descriptor: DEOXYHYPUSINE SYNTHASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Liao, D.-I, Davies, D.R.
Deposit date:1997-10-28
Release date:1998-02-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the NAD complex of human deoxyhypusine synthase: an enzyme with a ball-and-chain mechanism for blocking the active site.
Structure, 6, 1998
1CI4
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BU of 1ci4 by Molmil
THE CRYSTAL STRUCTURE OF HUMAN BARRIER-TO-AUTOINTEGRATION FACTOR (BAF)
Descriptor: PROTEIN (BARRIER-TO-AUTOINTEGRATION FACTOR (BAF))
Authors:Umland, T.C, Wei, S.-Q, Craigie, R, Davies, D.R.
Deposit date:1999-04-07
Release date:2000-08-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of DNA bridging by barrier-to-autointegration factor.
Biochemistry, 39, 2000
2KU0
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BU of 2ku0 by Molmil
Inhibitor Induced Structural Change in the HCV IRES Domain IIa RNA
Descriptor: (7S)-7-[(dimethylamino)methyl]-1-[3-(dimethylamino)propyl]-7,8-dihydro-1H-furo[3,2-e]benzimidazol-2-amine, HCV IRES Domain IIa RNA
Authors:Paulsen, R.B, Seth, P.P, Swayze, E.E, Griffey, R.H, Skalicky, J.J, Cheatham III, T.E, Davis, D.R.
Deposit date:2010-02-10
Release date:2010-04-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Inhibitor-induced structural change in the HCV IRES domain IIa RNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
2LPS
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BU of 2lps by Molmil
Molecular dynamics re-refinement of domain 5 of the yeast ai5(gamma) group II intron
Descriptor: RNA (34-MER)
Authors:Henriksen, N.M, Davis, D.R, Cheatham III, T.E.
Deposit date:2012-02-17
Release date:2012-08-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Molecular dynamics re-refinement of two different small RNA loop structures using the original NMR data suggest a common structure.
J.Biomol.Nmr, 53, 2012
2LPT
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BU of 2lpt by Molmil
Molecular dynamics re-refinement of domain 5 of the Pylaiella littoralis group II intron
Descriptor: RNA_(34-MER)
Authors:Henriksen, N.M, Davis, D.R, Cheatham III, T.E.
Deposit date:2012-02-17
Release date:2012-08-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Molecular dynamics re-refinement of two different small RNA loop structures using the original NMR data suggest a common structure.
J.Biomol.Nmr, 53, 2012
2BU1
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BU of 2bu1 by Molmil
MS2-RNA HAIRPIN (5BRU -5) COMPLEX
Descriptor: 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *5BU*AP*CP*CP*CP*AP*UP*GP*U)-3', MS2 COAT PROTEIN
Authors:Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L.
Deposit date:2005-06-08
Release date:2005-08-18
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex.
Rna, 7, 2001
2C50
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BU of 2c50 by Molmil
MS2-RNA HAIRPIN (A -5) COMPLEX
Descriptor: 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *AP*AP*CP*CP*CP*AP*UP*GP*U)-3', COAT PROTEIN
Authors:Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L.
Deposit date:2005-10-25
Release date:2006-01-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex.
Rna, 7, 2001
2C4Q
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BU of 2c4q by Molmil
MS2-RNA HAIRPIN (2ONE -5) COMPLEX
Descriptor: 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *PYO*AP*CP*CP*CP*AP*UP*GP*U)-3', COAT PROTEIN
Authors:Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L.
Deposit date:2005-10-21
Release date:2005-11-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex.
Rna, 7, 2001
2C51
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BU of 2c51 by Molmil
MS2-RNA HAIRPIN (G -5) COMPLEX
Descriptor: 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *GP*AP*CP*CP*CP*AP*UP*GP*U)-3', COAT PROTEIN
Authors:Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L.
Deposit date:2005-10-25
Release date:2006-01-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex.
Rna, 7, 2001
2C4Y
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BU of 2c4y by Molmil
MS2-RNA HAIRPIN (2THIOURACIL-5) COMPLEX
Descriptor: 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *SUR*AP*CP*CP*CP*AP*UP*GP*U)-3', Capsid protein
Authors:Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L.
Deposit date:2005-10-25
Release date:2006-01-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex.
Rna, 7, 2001
2C4Z
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BU of 2c4z by Molmil
MS2-RNA HAIRPIN (2SU -5-6) COMPLEX
Descriptor: 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*SUR *SUR*AP*CP*CP*CP*AP*UP*GP*U)-3', COAT PROTEIN
Authors:Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L.
Deposit date:2005-10-25
Release date:2006-01-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex.
Rna, 7, 2001
1KPQ
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BU of 1kpq by Molmil
Structure of the Tsg101 UEV domain
Descriptor: Tumor susceptibility gene 101 protein
Authors:Pornillos, O, Alam, S.L, Rich, R.L, Myszka, D.G, Davis, D.R, Sundquist, W.I.
Deposit date:2002-01-02
Release date:2002-05-25
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and functional interactions of the Tsg101 UEV domain.
EMBO J., 21, 2002
1KPP
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BU of 1kpp by Molmil
Structure of the Tsg101 UEV domain
Descriptor: Tumor susceptibility gene 101 protein
Authors:Pornillos, O, Alam, S.L, Rich, R.L, Myszka, D.G, Davis, D.R, Sundquist, W.I.
Deposit date:2002-01-02
Release date:2002-05-24
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and functional interactions of the Tsg101 UEV domain.
EMBO J., 21, 2002
1M4P
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BU of 1m4p by Molmil
Structure of the Tsg101 UEV domain in complex with a HIV-1 PTAP "late domain" peptide, DYANA Ensemble
Descriptor: Gag Polyprotein, Tumor Susceptibility gene 101 protein
Authors:Pornillos, O, Alam, S.L, Davis, D.R, Sundquist, W.I.
Deposit date:2002-07-03
Release date:2002-11-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein
Nat.Struct.Biol., 9, 2002
1M4Q
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BU of 1m4q by Molmil
STRUCTURE OF THE TSG101 UEV DOMAIN IN COMPLEX WITH A HIV-1 PTAP "LATE DOMAIN" PEPTIDE, CNS ENSEMBLE
Descriptor: Gag Polyprotein, Tumor Susceptibility gene 101 protein
Authors:Pornillos, O, Alam, S.L, Davis, D.R, Sundquist, W.I.
Deposit date:2002-07-03
Release date:2002-11-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein
Nat.Struct.Biol., 9, 2002
1BZ2
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BU of 1bz2 by Molmil
STABILIZATION OF THE ANTICODON STEM-LOOP OF TRNALYS,3 BY AN A+C BASE PAIR AND BY PSEUDOURIDINE, NMR, 1 STRUCTURE
Descriptor: TRNA
Authors:Durant, P.C, Davis, D.R.
Deposit date:1998-11-05
Release date:1999-04-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Stabilization of the anticodon stem-loop of tRNALys,3 by an A+-C base-pair and by pseudouridine.
J.Mol.Biol., 285, 1999
1BZT
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BU of 1bzt by Molmil
STABILIZATION OF THE ANTICODON STEM-LOOP OF TRNALYS,3 BY AN A+C BASE PAIR AND BY PSEUDOURIDINE, NMR, 1 STRUCTURE
Descriptor: TRNA
Authors:Durant, P.C, Davis, D.R.
Deposit date:1998-11-05
Release date:1999-04-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Stabilization of the anticodon stem-loop of tRNALys,3 by an A+-C base-pair and by pseudouridine.
J.Mol.Biol., 285, 1999
1BZU
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BU of 1bzu by Molmil
STABILIZATION OF THE ANTICODON STEM-LOOP OF TRNALYS, 3 BY AN A+C BASE PAIR AND BY PSEUDOURIDINE, NMR, 1 STRUCTURE
Descriptor: TRNA
Authors:Durant, P.C, Davis, D.R.
Deposit date:1998-11-05
Release date:1999-04-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Stabilization of the anticodon stem-loop of tRNALys,3 by an A+-C base-pair and by pseudouridine.
J.Mol.Biol., 285, 1999

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