Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6MBQ

Crystal structure of Mg-free wild-type KRAS (2-166) bound to GMPPNP in the state 1 conformation

Summary for 6MBQ
Entry DOI10.2210/pdb6mbq/pdb
DescriptorGTPase KRas, SODIUM ION, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywordskras, ras, mg, k-ras, small gtpase, guanine nucleotide, oncoprotein, gmppnp, gppnhp
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight19474.44
Authors
Dharmaiah, S.,Davies, D.R.,Abendroth, J.,Gillette, W.G.,Stephen, A.G.,Simanshu, D.K. (deposition date: 2018-08-30, release date: 2019-07-31, Last modification date: 2023-10-11)
Primary citationDharmaiah, S.,Tran, T.H.,Messing, S.,Agamasu, C.,Gillette, W.K.,Yan, W.,Waybright, T.,Alexander, P.,Esposito, D.,Nissley, D.V.,McCormick, F.,Stephen, A.G.,Simanshu, D.K.
Structures of N-terminally processed KRAS provide insight into the role of N-acetylation.
Sci Rep, 9:10512-10512, 2019
Cited by
PubMed: 31324887
DOI: 10.1038/s41598-019-46846-w
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.35 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon