1EPR
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![BU of 1epr by Molmil](/molmil-images/mine/1epr) | ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH PD-135,040 | Descriptor: | ENDOTHIAPEPSIN, N~2~-[(2R)-2-benzyl-3-(tert-butylsulfonyl)propanoyl]-N-{(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-[(2-morpholin-4-ylethyl)amino]-4-oxobutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide | Authors: | Badasso, M, Crawford, M, Cooper, J.B, Blundell, T.L. | Deposit date: | 1994-07-27 | Release date: | 1994-12-20 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica. Protein Sci., 3, 1994
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1Z3M
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![BU of 1z3m by Molmil](/molmil-images/mine/1z3m) | Crystal structure of mutant Ribonuclease S (F8Nva) | Descriptor: | Ribonuclease pancreatic, S-Peptide, S-protein, ... | Authors: | Das, M, Vasudeva Rao, B, Ghosh, S, Varadarajan, R. | Deposit date: | 2005-03-14 | Release date: | 2005-03-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Attempts to delineate the relative contributions of changes in hydrophobicity and packing to changes in stability of ribonuclease S mutants. Biochemistry, 44, 2005
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1Z3P
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![BU of 1z3p by Molmil](/molmil-images/mine/1z3p) | X-Ray crystal structure of a mutant Ribonuclease S (M13Nva) | Descriptor: | Ribonuclease pancreatic, S-Peptide, S-Protein, ... | Authors: | Das, M, Rao, B.V, Ghosh, S, Varadarajan, R. | Deposit date: | 2005-03-14 | Release date: | 2005-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Attempts to delineate the relative contributions of changes in hydrophobicity and packing to changes in stability of ribonuclease S mutants. Biochemistry, 44, 2005
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1Z3L
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![BU of 1z3l by Molmil](/molmil-images/mine/1z3l) | X-Ray Crystal Structure of a Mutant Ribonuclease S (F8Anb) | Descriptor: | Ribonuclease pancreatic, S-Peptide, S-Protein, ... | Authors: | Das, M, Vasudeva Rao, B, Ghosh, S, Varadarajan, R. | Deposit date: | 2005-03-14 | Release date: | 2005-03-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Attempts to delineate the relative contributions of changes in hydrophobicity and packing to changes in stability of ribonuclease S mutants. Biochemistry, 44, 2005
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6UNF
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![BU of 6unf by Molmil](/molmil-images/mine/6unf) | |
6NPQ
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![BU of 6npq by Molmil](/molmil-images/mine/6npq) | |
6NUG
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![BU of 6nug by Molmil](/molmil-images/mine/6nug) | hGRNA4-28_3s | Descriptor: | Granulin-4 | Authors: | Dastpeyman, M, Bansal, P, Wilson, D, Loukas, A, Smout, M, Daly, N. | Deposit date: | 2019-02-01 | Release date: | 2020-02-05 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | hGRN4-28_3s to be published
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7RE8
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![BU of 7re8 by Molmil](/molmil-images/mine/7re8) | |
7RE7
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![BU of 7re7 by Molmil](/molmil-images/mine/7re7) | TCR mimic antibody (Fab fragment) in complex with AFP/HLA-A*02 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, FORMIC ACID, ... | Authors: | Dasgupta, M, Baker, B.M. | Deposit date: | 2021-07-12 | Release date: | 2022-07-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.547 Å) | Cite: | Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma. Sci Rep, 12, 2022
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7RE9
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![BU of 7re9 by Molmil](/molmil-images/mine/7re9) | TCR mimic antibody (Fab fragment) | Descriptor: | DI(HYDROXYETHYL)ETHER, Fab heavy chain, Fab light chain | Authors: | Dasgupta, M, Baker, B.M. | Deposit date: | 2021-07-12 | Release date: | 2022-07-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma. Sci Rep, 12, 2022
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6UND
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![BU of 6und by Molmil](/molmil-images/mine/6und) | |
6E1L
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![BU of 6e1l by Molmil](/molmil-images/mine/6e1l) | GRN3Ala | Descriptor: | Granulin | Authors: | Dastpeyman, M, Bansal, P, Wilson, D, Sotillo, J, Brindley, P, Loukas, A, Smout, M, Daly, N. | Deposit date: | 2018-07-10 | Release date: | 2019-02-06 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural Variants of a Liver Fluke Derived Granulin Peptide Potently Stimulate Wound Healing. J. Med. Chem., 61, 2018
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4YK7
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![BU of 4yk7 by Molmil](/molmil-images/mine/4yk7) | |
1W97
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![BU of 1w97 by Molmil](/molmil-images/mine/1w97) | cyto-EpsL: the cytoplasmic domain of EpsL, an inner membrane component of the type II secretion system of Vibrio cholerae | Descriptor: | TYPE II SECRETION SYSTEM PROTEIN L | Authors: | Abendroth, J, Bagdasarian, M, Sansdkvist, M, Hol, W.G.J. | Deposit date: | 2004-10-06 | Release date: | 2004-11-30 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Structure of the Cytoplasmic Domain of Epsl, an Inner Membrane Component of the Type II Secretion System of Vibrio Cholerae: An Unusual Member of the Actin-Like ATPase Superfamily J.Mol.Biol., 344, 2004
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7SUC
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![BU of 7suc by Molmil](/molmil-images/mine/7suc) | |
7TBL
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![BU of 7tbl by Molmil](/molmil-images/mine/7tbl) | Composite structure of the human nuclear pore complex (NPC) cytoplasmic face generated with a 12A cryo-ET map of the purified HeLa cell NPC | Descriptor: | DDX19, ELYS, GLE1, ... | Authors: | Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. | Deposit date: | 2021-12-22 | Release date: | 2022-06-22 | Last modified: | 2022-06-29 | Method: | ELECTRON MICROSCOPY (23 Å) | Cite: | Architecture of the cytoplasmic face of the nuclear pore. Science, 376, 2022
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7TBM
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![BU of 7tbm by Molmil](/molmil-images/mine/7tbm) | Composite structure of the dilated human nuclear pore complex (NPC) generated with a 37A in situ cryo-ET map of CD4+ T cell NPC | Descriptor: | DDX19, NUP107 CTD, NUP107 NTD, ... | Authors: | Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. | Deposit date: | 2021-12-22 | Release date: | 2022-06-15 | Last modified: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (37 Å) | Cite: | Architecture of the cytoplasmic face of the nuclear pore. Science, 376, 2022
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8VPW
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![BU of 8vpw by Molmil](/molmil-images/mine/8vpw) | Pseudomonas fluorescens G150T isocyanide hydratase at 298 K XFEL data, free enzyme | Descriptor: | CHLORIDE ION, Isonitrile hydratase InhA | Authors: | Wilson, M.A, Smith, N, Dasgupta, M, Dolamore, C. | Deposit date: | 2024-01-17 | Release date: | 2024-02-21 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Changes in an enzyme ensemble during catalysis observed by high-resolution XFEL crystallography. Sci Adv, 10, 2024
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8VQ1
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![BU of 8vq1 by Molmil](/molmil-images/mine/8vq1) | Pseudomonas fluorescens G150T isocyanide hydratase at 298 K XFEL data, thioimidate intermediate | Descriptor: | CHLORIDE ION, Isonitrile hydratase InhA, N-(4-nitrophenyl)methanimine | Authors: | Wilson, M.A, Smith, N, Dasgupta, M, Dolamore, C. | Deposit date: | 2024-01-17 | Release date: | 2024-02-21 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Changes in an enzyme ensemble during catalysis observed by high-resolution XFEL crystallography. Sci Adv, 10, 2024
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7PER
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![BU of 7per by Molmil](/molmil-images/mine/7per) | Model of the inner ring of the human nuclear pore complex | Descriptor: | Nuclear pore complex protein Nup155, Nuclear pore complex protein Nup205, Nuclear pore complex protein Nup93, ... | Authors: | Schuller, A.P, Wojtynek, M, Mankus, D, Tatli, M, Kronenberg-Tenga, R, Regmi, S.G, Dasso, M, Weis, K, Medalia, O, Schwartz, T.U. | Deposit date: | 2021-08-11 | Release date: | 2021-10-20 | Last modified: | 2021-11-24 | Method: | ELECTRON MICROSCOPY (35 Å) | Cite: | The cellular environment shapes the nuclear pore complex architecture. Nature, 598, 2021
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6NI7
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6NIA
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6NI9
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6NI5
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6NI6
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![BU of 6ni6 by Molmil](/molmil-images/mine/6ni6) | |