2H27
 
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7MKJ
 | | Cryo-EM structure of Escherichia coli RNA polymerase bound to T7A1 promoter DNA | | Descriptor: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Saecker, R.M, Darst, S.A, Chen, J. | | Deposit date: | 2021-04-23 | | Release date: | 2021-09-29 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7MKD
 | | Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 1) | | Descriptor: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Saecker, R.M, Darst, S.A, Chen, J. | | Deposit date: | 2021-04-23 | | Release date: | 2021-09-29 | | Last modified: | 2021-10-13 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7MKE
 | | Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 2) | | Descriptor: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Saecker, R.M, Darst, S.A, Chen, J. | | Deposit date: | 2021-04-23 | | Release date: | 2021-09-29 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7MKI
 | | Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR (-5G to C) promoter DNA | | Descriptor: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Saecker, R.M, Darst, S.A, Chen, J. | | Deposit date: | 2021-04-23 | | Release date: | 2021-09-29 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
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4KI2
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4GZZ
 | | Crystal structures of bacterial RNA Polymerase paused elongation complexes | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Weixlbaumer, A, Leon, K, Landick, R, Darst, S.A. | | Deposit date: | 2012-09-06 | | Release date: | 2013-02-13 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (4.2927 Å) | | Cite: | Structural basis of transcriptional pausing in bacteria.
Cell(Cambridge,Mass.), 152, 2013
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4GZY
 | | Crystal structures of bacterial RNA Polymerase paused elongation complexes | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Weixlbaumer, A, Leon, K, Landick, R, Darst, S.A. | | Deposit date: | 2012-09-06 | | Release date: | 2013-02-13 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.5054 Å) | | Cite: | Structural basis of transcriptional pausing in bacteria.
Cell(Cambridge,Mass.), 152, 2013
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7KIN
 | | Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoter | | Descriptor: | DNA (49-MER), DNA (54-MER), DNA-directed RNA polymerase subunit alpha, ... | | Authors: | Lilic, M, Darst, S.A, Campbell, E.A. | | Deposit date: | 2020-10-23 | | Release date: | 2021-04-21 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.74 Å) | | Cite: | Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.
Mol.Cell, 81, 2021
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7KRN
 | | Structure of SARS-CoV-2 backtracked complex bound to nsp13 helicase - nsp13(1)-BTC | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ... | | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | | Deposit date: | 2020-11-20 | | Release date: | 2021-04-21 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7KIF
 | | Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 transcription factor | | Descriptor: | DNA (55-MER), DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ... | | Authors: | Lilic, M, Darst, S.A, Campbell, E.A. | | Deposit date: | 2020-10-23 | | Release date: | 2021-04-21 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.
Mol.Cell, 81, 2021
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7KRP
 | | Structure of SARS-CoV-2 backtracked complex complex bound to nsp13 helicase - BTC (local refinement) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHAPSO, MAGNESIUM ION, ... | | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | | Deposit date: | 2020-11-20 | | Release date: | 2021-04-21 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7KIM
 | | Mycobacterium tuberculosis WT RNAP transcription closed promoter complex with WhiB7 transcription factor | | Descriptor: | DNA (45-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Lilic, M, Darst, S.A, Campbell, E.A. | | Deposit date: | 2020-10-23 | | Release date: | 2021-04-21 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.
Mol.Cell, 81, 2021
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7KRO
 | | Structure of SARS-CoV-2 backtracked complex complex bound to nsp13 helicase - nsp13(2)-BTC | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ... | | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | | Deposit date: | 2020-11-20 | | Release date: | 2021-04-21 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
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4L6Y
 | | Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1) | | Descriptor: | Protein regulator of cytokinesis 1 | | Authors: | Subramanian, R, Ti, S, Tan, L, Darst, S.A, Kapoor, T.M. | | Deposit date: | 2013-06-13 | | Release date: | 2013-07-17 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.3015 Å) | | Cite: | Marking and Measuring Single Microtubules by PRC1 and Kinesin-4.
Cell(Cambridge,Mass.), 154, 2013
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4L5G
 | | Crystal structure of Thermus thermophilus CarD | | Descriptor: | CarD | | Authors: | Srivastava, D.B, Westblade, L.F, Campbell, E.A, Darst, S.A. | | Deposit date: | 2013-06-11 | | Release date: | 2013-07-31 | | Last modified: | 2013-08-21 | | Method: | X-RAY DIFFRACTION (2.3902 Å) | | Cite: | Structure and function of CarD, an essential mycobacterial transcription factor.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3MGC
 | | Teg12 Apo | | Descriptor: | GLYCEROL, IMIDAZOLE, N-L-ALPHA-ASPARTYL L-PHENYLALANINE 1-METHYL ESTER, ... | | Authors: | Bick, M.J, Banik, J.J, Darst, S.A, Brady, S.F. | | Deposit date: | 2010-04-05 | | Release date: | 2010-06-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Crystal structures of the glycopeptide sulfotransferase Teg12 in a complex with the teicoplanin aglycone.
Biochemistry, 49, 2010
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3MG9
 | | Teg 12 Binary Structure Complexed with the Teicoplanin Aglycone | | Descriptor: | FORMIC ACID, GLYCEROL, TEG12, ... | | Authors: | Bick, M.J, Banik, J.J, Darst, S.A, Brady, S.F. | | Deposit date: | 2010-04-05 | | Release date: | 2010-06-09 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | Crystal Structures of the Glycopeptide Sulfotransferase Teg12 in a Complex with the Teicoplanin Aglycone.
Biochemistry, 49, 2010
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4L3I
 | | Structure of the microtubule associated protein PRC1 (Protein Regulator of Cytokinesis 1) | | Descriptor: | Protein regulator of cytokinesis 1 | | Authors: | Subramanian, R, Ti, S, Tan, L, Darst, S.A, Kapoor, T.M. | | Deposit date: | 2013-06-06 | | Release date: | 2013-07-17 | | Last modified: | 2013-08-07 | | Method: | X-RAY DIFFRACTION (3.6005 Å) | | Cite: | Marking and Measuring Single Microtubules by PRC1 and Kinesin-4.
Cell(Cambridge,Mass.), 154, 2013
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4LK1
 | | Crystal Structure Analysis of the E.coli holoenzyme | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Bae, B, Darst, S.A. | | Deposit date: | 2013-07-05 | | Release date: | 2013-11-13 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.8369 Å) | | Cite: | Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3NIB
 | | Teg14 Apo | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Teg14 | | Authors: | Bick, M.J, Banik, J.J, Darst, S.A, Brady, S.F. | | Deposit date: | 2010-06-15 | | Release date: | 2010-12-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The 2.7 A resolution structure of the glycopeptide sulfotransferase Teg14
Acta Crystallogr.,Sect.D, 66, 2010
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4LLG
 | | Crystal Structure Analysis of the E.coli holoenzyme/Gp2 complex | | Descriptor: | Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Bae, B, Darst, S.A. | | Deposit date: | 2013-07-09 | | Release date: | 2013-11-13 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.7936 Å) | | Cite: | Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3MGB
 | | Teg 12 Ternary Structure Complexed with PAP and the Teicoplanin Aglycone | | Descriptor: | 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, ACETATE ION, CHLORIDE ION, ... | | Authors: | Bick, M.J, Banik, J.J, Darst, S.A, Brady, S.F. | | Deposit date: | 2010-04-05 | | Release date: | 2010-06-09 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Crystal Structures of the Glycopeptide Sulfotransferase Teg12 in a Complex with the Teicoplanin Aglycone.
Biochemistry, 49, 2010
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4LJZ
 | | Crystal Structure Analysis of the E.coli holoenzyme | | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | Authors: | Bae, B, Darst, S.A. | | Deposit date: | 2013-07-05 | | Release date: | 2013-11-13 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.5871 Å) | | Cite: | Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4LK0
 | | Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex | | Descriptor: | Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Bae, B, Darst, S.A. | | Deposit date: | 2013-07-05 | | Release date: | 2013-11-13 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.9103 Å) | | Cite: | Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
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