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PDB: 1599 results

3F80
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BU of 3f80 by Molmil
(S)-2-amino-6-nitrohexanoic acid binds to human arginase I through multiple nitro-metal coordination interactions in the binuclear manganese cluster. Resolution 1.60 A.
Descriptor: 6-nitro-L-norleucine, Arginase-1, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2008-11-10
Release date:2008-12-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:(S)-2-Amino-6-nitrohexanoic Acid Binds to Human Arginase I through Multiple Nitro-Metal Coordination Interactions in the Binuclear Manganese Cluster.
J.Am.Chem.Soc., 130, 2008
3E8Z
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BU of 3e8z by Molmil
X-ray structure of rat arginase I-N130A mutant: the unliganded complex
Descriptor: Arginase-1, MANGANESE (II) ION
Authors:Shishova, E.Y, Di Costanzo, L, Christianson, D.W.
Deposit date:2008-08-20
Release date:2008-12-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
4GWC
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BU of 4gwc by Molmil
Crystal Structure of Mn2+2,Zn2+-Human Arginase I
Descriptor: Arginase-1, MANGANESE (II) ION, ZINC ION
Authors:D'Antonio, E.L, Hai, Y, Christianson, D.W.
Deposit date:2012-09-01
Release date:2012-09-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and function of non-native metal clusters in human arginase I.
Biochemistry, 51, 2012
6BS6
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BU of 6bs6 by Molmil
SusG with mixed linkage amylosaccharide
Descriptor: ACETATE ION, Alpha-amylase SusG, CALCIUM ION, ...
Authors:Koropatkin, N.M, Cockburn, D.W.
Deposit date:2017-12-01
Release date:2018-01-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural basis for the flexible recognition of alpha-glucan substrates by Bacteroides thetaiotaomicron SusG.
Protein Sci., 27, 2018
7UG6
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BU of 7ug6 by Molmil
Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Yelland, J.N, Bravo, J.P.K, Black, J.J.B, Taylor, D.W, Johnson, A.W.
Deposit date:2022-03-24
Release date:2022-12-21
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:A single 2'-O-methylation of ribosomal RNA gates assembly of a functional ribosome.
Nat.Struct.Mol.Biol., 30, 2023
3DJ8
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BU of 3dj8 by Molmil
Synthesis of (2S)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase I
Descriptor: 6-[(2R)-oxiran-2-yl]-L-norleucine, Arginase-1, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2008-06-22
Release date:2008-07-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Synthesis of (2S)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase I
Org.Biomol.Chem., 6, 2008
4HE0
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BU of 4he0 by Molmil
Crystal structure of human muscle fructose-1,6-bisphosphatase
Descriptor: CHLORIDE ION, Fructose-1,6-bisphosphatase isozyme 2, MAGNESIUM ION, ...
Authors:Shi, R, Zhu, D.W, Lin, S.X.
Deposit date:2012-10-03
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway.
Plos One, 8, 2013
6CGP
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BU of 6cgp by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with MAIP-032
Descriptor: 1,2-ETHANEDIOL, Hdac6 protein, N-hydroxy-4-[(2-propylimidazo[1,2-a]pyridin-3-yl)amino]benzamide, ...
Authors:Osko, J.D, Christianson, D.W.
Deposit date:2018-02-20
Release date:2018-06-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Multicomponent Synthesis and Binding Mode of Imidazo[1,2- a]pyridine-Capped Selective HDAC6 Inhibitors.
Org. Lett., 20, 2018
3DOP
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BU of 3dop by Molmil
Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 5beta-dihydrotestosterone, Resolution 2.00A
Descriptor: 3-oxo-5-beta-steroid 4-dehydrogenase, 5-beta-DIHYDROTESTOSTERONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Di Costanzo, L, Drury, J.E, Penning, T.M, Christianson, D.W.
Deposit date:2008-07-05
Release date:2008-10-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and catalytic mechanism of human steroid 5beta-reductase (AKR1D1)
Mol.Cell.Endocrinol., 301, 2009
3G4F
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BU of 3g4f by Molmil
Crystal Structure of (+)- -Cadinene Synthase from Gossypium arboreum in complex with 2-fluorofarnesyl diphosphate
Descriptor: (+)-delta-cadinene synthase isozyme XC1, (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, BETA-MERCAPTOETHANOL, ...
Authors:Gennadios, H.A, Di Costanzo, L, Christianson, D.W.
Deposit date:2009-02-03
Release date:2009-06-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.651 Å)
Cite:Crystal structure of (+)-delta-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis.
Biochemistry, 48, 2009
4GSV
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BU of 4gsv by Molmil
Crystal Structure of the Ni2+2-Human Arginase I-ABH complex
Descriptor: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, NICKEL (II) ION
Authors:D'Antonio, E.L, Hai, Y, Christianson, D.W.
Deposit date:2012-08-28
Release date:2012-09-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structure and function of non-native metal clusters in human arginase I.
Biochemistry, 51, 2012
3BJ8
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BU of 3bj8 by Molmil
Spermine/spermidine N1-acetyltransferase from mouse: Crystal structure of a ternary complex reveals solvent-mediated spermine binding
Descriptor: COENZYME A, Diamine acetyltransferase 1, SPERMINE
Authors:Montemayor, E.J, Hoffman, D.W.
Deposit date:2007-12-03
Release date:2008-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of spermidine/spermine N1-acetyltransferase in complex with spermine provides insights into substrate binding and catalysis.
Biochemistry, 47, 2008
4HE2
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BU of 4he2 by Molmil
Crystal structure of human muscle fructose-1,6-bisphosphatase Q32R mutant complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Fructose-1,6-bisphosphatase isozyme 2, ...
Authors:Shi, R, Zhu, D.W, Lin, S.X.
Deposit date:2012-10-03
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway.
Plos One, 8, 2013
3GN0
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BU of 3gn0 by Molmil
Crystal structure of human arginase I in complex with difluoromethylornithine (DFMO)
Descriptor: ALPHA-DIFLUOROMETHYLORNITHINE, Arginase-1, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2009-03-15
Release date:2010-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding of alpha,alpha-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design
J.Med.Chem., 54, 2011
4EWD
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BU of 4ewd by Molmil
Study on structure and function relationships in human Pirin with Mn ion
Descriptor: MANGANESE (II) ION, Pirin
Authors:Liu, F, Rehmani, I, Chen, L, Fu, R, Serrano, V, Wilson, D.W, Liu, A.
Deposit date:2012-04-26
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Pirin is an iron-dependent redox regulator of NF-kappa B.
Proc.Natl.Acad.Sci.USA, 110, 2013
3E8Q
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BU of 3e8q by Molmil
X-ray structure of rat arginase I-T135A: the unliganded complex
Descriptor: Arginase-1, MANGANESE (II) ION
Authors:Shishova, E.Y, Di Costanzo, L, Emig, F.A, Ash, D.E, Christianson, D.W.
Deposit date:2008-08-20
Release date:2008-12-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
3E6K
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BU of 3e6k by Molmil
X-ray structure of Human Arginase I: the mutant D183A in complex with ABH
Descriptor: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2008-08-15
Release date:2008-12-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
3E6V
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BU of 3e6v by Molmil
X-ray structure of human arginase I-D183N mutant: the complex with ABH
Descriptor: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2008-08-16
Release date:2008-12-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
4HE1
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BU of 4he1 by Molmil
Crystal structure of human muscle fructose-1,6-bisphosphatase Q32R mutant complex with fructose-6-phosphate and phosphate
Descriptor: 6-O-phosphono-beta-D-fructofuranose, CHLORIDE ION, Fructose-1,6-bisphosphatase isozyme 2, ...
Authors:Shi, R, Zhu, D.W, Lin, S.X.
Deposit date:2012-10-03
Release date:2013-10-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway.
Plos One, 8, 2013
3BNX
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BU of 3bnx by Molmil
Crystal structure of Aristolochene synthase complexed with farnesyl diphosphate
Descriptor: Aristolochene synthase, BETA-MERCAPTOETHANOL, FARNESYL DIPHOSPHATE, ...
Authors:Shishova, E.Y, Christianson, D.W.
Deposit date:2007-12-14
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray Crystallographic Studies of Substrate Binding to Aristolochene Synthase Suggest a Metal Ion Binding Sequence for Catalysis
J.Biol.Chem., 283, 2008
6CSR
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BU of 6csr by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with phenylhydroxamate
Descriptor: 1,2-ETHANEDIOL, BENZHYDROXAMIC ACID, Hdac6 protein, ...
Authors:Porter, N.J, Christianson, D.W.
Deposit date:2018-03-21
Release date:2018-05-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.619 Å)
Cite:Entropy as a Driver of Selectivity for Inhibitor Binding to Histone Deacetylase 6.
Biochemistry, 57, 2018
3BZ5
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BU of 3bz5 by Molmil
Functional domain of InlJ from Listeria monocytogenes includes a cysteine ladder
Descriptor: CHLORIDE ION, Internalin-J, SULFATE ION
Authors:Bublitz, M, Holland, C, Sabet, C, Reichelt, J, Cossart, P, Heinz, D.W, Bierne, H, Schubert, W.D.
Deposit date:2008-01-17
Release date:2008-06-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure and standardized geometric analysis of InlJ, a listerial virulence factor and leucine-rich repeat protein with a novel cysteine ladder.
J.Mol.Biol., 378, 2008
6DFK
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BU of 6dfk by Molmil
Crystal structure of the 11S subunit of the Plasmodium falciparum proteasome, PA28
Descriptor: SULFATE ION, Subunit of proteaseome activator complex,putative
Authors:Xie, S.C, Metcalfe, R.D, Gillett, D.L, Tilley, L, Griffin, M.D.W.
Deposit date:2018-05-15
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis.
Nat Microbiol, 4, 2019
6DVL
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BU of 6dvl by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with DDK-115
Descriptor: Hdac6 protein, N-[2-(cyclohexylamino)-2-oxoethyl]-N-{[4-(hydroxycarbamoyl)phenyl]methyl}-3,5-dimethylbenzamide, POTASSIUM ION, ...
Authors:Porter, N.J, Christianson, D.W.
Deposit date:2018-06-24
Release date:2018-08-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity.
J. Med. Chem., 61, 2018
6DVN
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BU of 6dvn by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with DDK-137
Descriptor: 1,2-ETHANEDIOL, Hdac6 protein, N-[2-(benzylamino)-2-oxoethyl]-4-(dimethylamino)-N-{[4-(hydroxycarbamoyl)phenyl]methyl}benzamide, ...
Authors:Osko, J.D, Christianson, D.W.
Deposit date:2018-06-24
Release date:2018-08-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity.
J. Med. Chem., 61, 2018

224201

數據於2024-08-28公開中

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