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PDB: 1599 件

3F80
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(S)-2-amino-6-nitrohexanoic acid binds to human arginase I through multiple nitro-metal coordination interactions in the binuclear manganese cluster. Resolution 1.60 A.
分子名称: 6-nitro-L-norleucine, Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2008-11-10
公開日2008-12-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献(S)-2-Amino-6-nitrohexanoic Acid Binds to Human Arginase I through Multiple Nitro-Metal Coordination Interactions in the Binuclear Manganese Cluster.
J.Am.Chem.Soc., 130, 2008
3E8Z
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X-ray structure of rat arginase I-N130A mutant: the unliganded complex
分子名称: Arginase-1, MANGANESE (II) ION
著者Shishova, E.Y, Di Costanzo, L, Christianson, D.W.
登録日2008-08-20
公開日2008-12-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
4GWC
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Crystal Structure of Mn2+2,Zn2+-Human Arginase I
分子名称: Arginase-1, MANGANESE (II) ION, ZINC ION
著者D'Antonio, E.L, Hai, Y, Christianson, D.W.
登録日2012-09-01
公開日2012-09-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and function of non-native metal clusters in human arginase I.
Biochemistry, 51, 2012
6BS6
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SusG with mixed linkage amylosaccharide
分子名称: ACETATE ION, Alpha-amylase SusG, CALCIUM ION, ...
著者Koropatkin, N.M, Cockburn, D.W.
登録日2017-12-01
公開日2018-01-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural basis for the flexible recognition of alpha-glucan substrates by Bacteroides thetaiotaomicron SusG.
Protein Sci., 27, 2018
7UG6
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Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Yelland, J.N, Bravo, J.P.K, Black, J.J.B, Taylor, D.W, Johnson, A.W.
登録日2022-03-24
公開日2022-12-21
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献A single 2'-O-methylation of ribosomal RNA gates assembly of a functional ribosome.
Nat.Struct.Mol.Biol., 30, 2023
3DJ8
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Synthesis of (2S)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase I
分子名称: 6-[(2R)-oxiran-2-yl]-L-norleucine, Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2008-06-22
公開日2008-07-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Synthesis of (2S)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase I
Org.Biomol.Chem., 6, 2008
4HE0
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Crystal structure of human muscle fructose-1,6-bisphosphatase
分子名称: CHLORIDE ION, Fructose-1,6-bisphosphatase isozyme 2, MAGNESIUM ION, ...
著者Shi, R, Zhu, D.W, Lin, S.X.
登録日2012-10-03
公開日2013-10-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway.
Plos One, 8, 2013
6CGP
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BU of 6cgp by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with MAIP-032
分子名称: 1,2-ETHANEDIOL, Hdac6 protein, N-hydroxy-4-[(2-propylimidazo[1,2-a]pyridin-3-yl)amino]benzamide, ...
著者Osko, J.D, Christianson, D.W.
登録日2018-02-20
公開日2018-06-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Multicomponent Synthesis and Binding Mode of Imidazo[1,2- a]pyridine-Capped Selective HDAC6 Inhibitors.
Org. Lett., 20, 2018
3DOP
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Crystal structure of 5beta-reductase (AKR1D1) in complex with NADP+ and 5beta-dihydrotestosterone, Resolution 2.00A
分子名称: 3-oxo-5-beta-steroid 4-dehydrogenase, 5-beta-DIHYDROTESTOSTERONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Di Costanzo, L, Drury, J.E, Penning, T.M, Christianson, D.W.
登録日2008-07-05
公開日2008-10-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and catalytic mechanism of human steroid 5beta-reductase (AKR1D1)
Mol.Cell.Endocrinol., 301, 2009
3G4F
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Crystal Structure of (+)- -Cadinene Synthase from Gossypium arboreum in complex with 2-fluorofarnesyl diphosphate
分子名称: (+)-delta-cadinene synthase isozyme XC1, (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, BETA-MERCAPTOETHANOL, ...
著者Gennadios, H.A, Di Costanzo, L, Christianson, D.W.
登録日2009-02-03
公開日2009-06-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.651 Å)
主引用文献Crystal structure of (+)-delta-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis.
Biochemistry, 48, 2009
4GSV
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BU of 4gsv by Molmil
Crystal Structure of the Ni2+2-Human Arginase I-ABH complex
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, NICKEL (II) ION
著者D'Antonio, E.L, Hai, Y, Christianson, D.W.
登録日2012-08-28
公開日2012-09-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Structure and function of non-native metal clusters in human arginase I.
Biochemistry, 51, 2012
3BJ8
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Spermine/spermidine N1-acetyltransferase from mouse: Crystal structure of a ternary complex reveals solvent-mediated spermine binding
分子名称: COENZYME A, Diamine acetyltransferase 1, SPERMINE
著者Montemayor, E.J, Hoffman, D.W.
登録日2007-12-03
公開日2008-09-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of spermidine/spermine N1-acetyltransferase in complex with spermine provides insights into substrate binding and catalysis.
Biochemistry, 47, 2008
4HE2
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Crystal structure of human muscle fructose-1,6-bisphosphatase Q32R mutant complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, Fructose-1,6-bisphosphatase isozyme 2, ...
著者Shi, R, Zhu, D.W, Lin, S.X.
登録日2012-10-03
公開日2013-10-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway.
Plos One, 8, 2013
3GN0
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Crystal structure of human arginase I in complex with difluoromethylornithine (DFMO)
分子名称: ALPHA-DIFLUOROMETHYLORNITHINE, Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2009-03-15
公開日2010-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Binding of alpha,alpha-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design
J.Med.Chem., 54, 2011
4EWD
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BU of 4ewd by Molmil
Study on structure and function relationships in human Pirin with Mn ion
分子名称: MANGANESE (II) ION, Pirin
著者Liu, F, Rehmani, I, Chen, L, Fu, R, Serrano, V, Wilson, D.W, Liu, A.
登録日2012-04-26
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Pirin is an iron-dependent redox regulator of NF-kappa B.
Proc.Natl.Acad.Sci.USA, 110, 2013
3E8Q
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X-ray structure of rat arginase I-T135A: the unliganded complex
分子名称: Arginase-1, MANGANESE (II) ION
著者Shishova, E.Y, Di Costanzo, L, Emig, F.A, Ash, D.E, Christianson, D.W.
登録日2008-08-20
公開日2008-12-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
3E6K
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X-ray structure of Human Arginase I: the mutant D183A in complex with ABH
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2008-08-15
公開日2008-12-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
3E6V
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X-ray structure of human arginase I-D183N mutant: the complex with ABH
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase-1, MANGANESE (II) ION
著者Di Costanzo, L, Christianson, D.W.
登録日2008-08-16
公開日2008-12-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
4HE1
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Crystal structure of human muscle fructose-1,6-bisphosphatase Q32R mutant complex with fructose-6-phosphate and phosphate
分子名称: 6-O-phosphono-beta-D-fructofuranose, CHLORIDE ION, Fructose-1,6-bisphosphatase isozyme 2, ...
著者Shi, R, Zhu, D.W, Lin, S.X.
登録日2012-10-03
公開日2013-10-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway.
Plos One, 8, 2013
3BNX
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Crystal structure of Aristolochene synthase complexed with farnesyl diphosphate
分子名称: Aristolochene synthase, BETA-MERCAPTOETHANOL, FARNESYL DIPHOSPHATE, ...
著者Shishova, E.Y, Christianson, D.W.
登録日2007-12-14
公開日2008-03-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray Crystallographic Studies of Substrate Binding to Aristolochene Synthase Suggest a Metal Ion Binding Sequence for Catalysis
J.Biol.Chem., 283, 2008
6CSR
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BU of 6csr by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with phenylhydroxamate
分子名称: 1,2-ETHANEDIOL, BENZHYDROXAMIC ACID, Hdac6 protein, ...
著者Porter, N.J, Christianson, D.W.
登録日2018-03-21
公開日2018-05-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.619 Å)
主引用文献Entropy as a Driver of Selectivity for Inhibitor Binding to Histone Deacetylase 6.
Biochemistry, 57, 2018
3BZ5
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Functional domain of InlJ from Listeria monocytogenes includes a cysteine ladder
分子名称: CHLORIDE ION, Internalin-J, SULFATE ION
著者Bublitz, M, Holland, C, Sabet, C, Reichelt, J, Cossart, P, Heinz, D.W, Bierne, H, Schubert, W.D.
登録日2008-01-17
公開日2008-06-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure and standardized geometric analysis of InlJ, a listerial virulence factor and leucine-rich repeat protein with a novel cysteine ladder.
J.Mol.Biol., 378, 2008
6DFK
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Crystal structure of the 11S subunit of the Plasmodium falciparum proteasome, PA28
分子名称: SULFATE ION, Subunit of proteaseome activator complex,putative
著者Xie, S.C, Metcalfe, R.D, Gillett, D.L, Tilley, L, Griffin, M.D.W.
登録日2018-05-15
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis.
Nat Microbiol, 4, 2019
6DVL
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BU of 6dvl by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with DDK-115
分子名称: Hdac6 protein, N-[2-(cyclohexylamino)-2-oxoethyl]-N-{[4-(hydroxycarbamoyl)phenyl]methyl}-3,5-dimethylbenzamide, POTASSIUM ION, ...
著者Porter, N.J, Christianson, D.W.
登録日2018-06-24
公開日2018-08-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity.
J. Med. Chem., 61, 2018
6DVN
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Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with DDK-137
分子名称: 1,2-ETHANEDIOL, Hdac6 protein, N-[2-(benzylamino)-2-oxoethyl]-4-(dimethylamino)-N-{[4-(hydroxycarbamoyl)phenyl]methyl}benzamide, ...
著者Osko, J.D, Christianson, D.W.
登録日2018-06-24
公開日2018-08-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity.
J. Med. Chem., 61, 2018

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件を2024-08-28に公開中

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