5IJD
 
 | | The crystal structure of mouse TLR4/MD-2/lipid A complex | | 分子名称: | (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wang, Y, Su, L, Morin, M.D, Jones, B.T, Whitby, L.R, Surakattula, M, Huang, H, Shi, H, Choi, J.H, Wang, K, Moresco, E.M, Berger, M, Zhan, X, Zhang, H, Boger, D.L, Beutler, B. | | 登録日 | 2016-03-01 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
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1PIL
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5IWO
 | | Bacterial sodium channel pore domain, low bromide | | 分子名称: | BROMIDE ION, Ion transport protein | | 著者 | Shaya, D, Findeisen, F, Rohaim, A, Minor, D.L. | | 登録日 | 2016-03-22 | | 公開日 | 2016-03-30 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.33 Å) | | 主引用文献 | Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation.
Cell, 164, 2016
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5MCS
 | | Solution structure and dynamics of the outer membrane cytochrome OmcF from Geobacter sulfurreducens | | 分子名称: | HEME C, Lipoprotein cytochrome c, 1 heme-binding site | | 著者 | Dantas, J.M, Silva, M.A, Morgado, L, Pantoja-Uceda, D, Turner, D.L, Bruix, M, Salgueiro, C.A. | | 登録日 | 2016-11-10 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and dynamics of the outer membrane cytochrome OmcF from Geobacter sulfurreducens.
Biochim. Biophys. Acta, 1858, 2017
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5EGM
 | | Development of a novel tricyclic class of potent and selective FIXa inhibitors | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-chloranyl-~{N}-[(7~{S})-2-methyl-7-phenyl-10-(1~{H}-1,2,3,4-tetrazol-5-yl)-8,9-dihydro-6~{H}-pyrido[1,2-a]indol-7-yl]-4-(1,2,4-triazol-4-yl)benzamide, Coagulation factor IX, ... | | 著者 | Meng, D, Andre, P, Bateman, T.J, Berger, R, Chen, Y, Desai, K, Dewnani, S, Ellsworth, K, Feng, D, Geissler, W.M, Guo, L, Hruza, A, Jian, T, Li, H, Parker, D.L, Reichert, P, Sherer, E.C, Smith, C.J, Sonatore, L.M, Tschirret-Guth, R, Wu, J, Xu, J, Zhang, T, Campeau, L, Orr, R, Poirier, M, McCabe-Dunn, j, Araki, K, Nishimura, T, Sakurada, I, Hirabayashi, T, Wood, H.B. | | 登録日 | 2015-10-27 | | 公開日 | 2015-11-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.841 Å) | | 主引用文献 | Development of a novel tricyclic class of potent and selective FIXa inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
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5FOY
 | | De novo structure of the binary mosquito larvicide BinAB at pH 7 | | 分子名称: | 41.9 KDA INSECTICIDAL TOXIN, LARVICIDAL TOXIN 51 KDA PROTEIN | | 著者 | Colletier, J.P, Sawaya, M.R, Gingery, M, Rodriguez, J.A, Cascio, D, Brewster, A.S, Michels-Clark, T, Boutet, S, Williams, G.J, Messerschmidt, M, DePonte, D.P, Sierra, R.G, Laksmono, H, Koglin, J.E, Hunter, M.S, W Park, H, Uervirojnangkoorn, M, Bideshi, D.L, Brunger, A.T, Federici, B.A, Sauter, N.K, Eisenberg, D.S. | | 登録日 | 2015-11-26 | | 公開日 | 2016-10-05 | | 最終更新日 | 2019-08-28 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | De Novo Phasing with X-Ray Laser Reveals Mosquito Larvicide Binab Structure.
Nature, 539, 2016
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1K4J
 | | Crystal Structure of the Acyl-homoserinelactone Synthase EsaI Complexed with Rhenate | | 分子名称: | PERRHENATE, acyl-homoserinelactone synthase EsaI | | 著者 | Watson, W.T, Minogue, T.D, Val, D.L, Beck von Bodman, S, Churchill, M.E.A. | | 登録日 | 2001-10-08 | | 公開日 | 2002-04-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis and specificity of acyl-homoserine lactone signal production in bacterial quorum sensing.
Mol.Cell, 9, 2002
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8R9W
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8R9Y
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1EIA
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8R9Z
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8R9X
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5FUA
 | | Cryo-EM of BK polyomavirus | | 分子名称: | MAJOR CAPSID PROTEIN VP1 | | 著者 | Hurdiss, D.L, Morgan, E.L, Thompson, R.F, Prescott, E.L, Panou, M.M, Macdonald, A, Ranson, N.A. | | 登録日 | 2016-01-22 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | | 主引用文献 | New Structural Insights Into the Genome and Minor Capsid Proteins of Bk Polyomavirus Using Cryo-Electron Microscopy.
Structure, 24, 2016
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5MRW
 | | Structure of the KdpFABC complex | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, POTASSIUM ION, Potassium-transporting ATPase ATP-binding subunit, ... | | 著者 | Huang, C, Pedersen, B.P, Stokes, D.L. | | 登録日 | 2016-12-27 | | 公開日 | 2017-06-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the potassium-importing KdpFABC membrane complex.
Nature, 546, 2017
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5IWN
 | | Bacterial sodium channel pore domain, high bromide | | 分子名称: | BROMIDE ION, Ion transport protein | | 著者 | Shaya, D, Findeisen, F, Rohaim, A, Minor, D.L. | | 登録日 | 2016-03-22 | | 公開日 | 2016-03-30 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.75 Å) | | 主引用文献 | Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation.
Cell, 164, 2016
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5FOZ
 | | De novo structure of the binary mosquito larvicide BinAB at pH 10 | | 分子名称: | LARVICIDAL TOXIN PROTEIN, SODIUM ION, TOXIN | | 著者 | Colletier, J.P, Sawaya, M.R, Gingery, M, Rodriguez, J.A, Cascio, D, Brewster, A.S, Michels-Clark, T, Boutet, S, Williams, G.J, Messerschmidt, M, DePonte, D.P, Sierra, R.G, Laksmono, H, Koglin, J.E, Hunter, M.S, W Park, H, Uervirojnangkoorn, M, Bideshi, D.L, Brunger, A.T, Federici, B.A, Sauter, N.K, Eisenberg, D.S. | | 登録日 | 2015-11-26 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | De Novo Phasing with X-Ray Laser Reveals Mosquito Larvicide Binab Structure.
Nature, 539, 2016
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1JNB
 | | CONNECTOR PROTEIN FROM BACTERIOPHAGE PHI29 | | 分子名称: | UPPER COLLAR PROTEIN | | 著者 | Simpson, A.A, Leiman, P.G, Tao, Y, He, Y, Badasso, M.O, Jardine, P.J, Anderson, D.L, Rossmann, M.G. | | 登録日 | 2001-07-23 | | 公開日 | 2001-08-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure determination of the head-tail connector of bacteriophage phi29.
Acta Crystallogr.,Sect.D, 57, 2001
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5KZL
 | | Structure of Heme Oxygenase from Leptospira interrogans | | 分子名称: | Heme oxygenase, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Klinke, S, Soldano, A, Otero, L.H, Rivera, M, Catalano-Dupuy, D.L, Ceccarelli, E.A. | | 登録日 | 2016-07-25 | | 公開日 | 2017-07-26 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Structural and mutational analyses of the Leptospira interrogans virulence-related heme oxygenase provide insights into its catalytic mechanism.
PLoS ONE, 12, 2017
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1POA
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1DSX
 | | KV1.2 T1 DOMAIN, RESIDUES 33-119, T46V MUTANT | | 分子名称: | PROTEIN (KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL) | | 著者 | Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Avelar, A, Jan, Y.N, Jan, L.Y, Berger, J.M. | | 登録日 | 2000-01-10 | | 公開日 | 2000-09-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel.
Cell(Cambridge,Mass.), 102, 2000
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5E96
 | | Crystal structure of aminoglycoside 6'-acetyltransferase type Ii | | 分子名称: | 1,2-ETHANEDIOL, Aminoglycoside 6'-acetyltransferase, PHOSPHATE ION | | 著者 | Berghuis, A.M, Burk, D.L, Baettig, O.M, Shi, K. | | 登録日 | 2015-10-14 | | 公開日 | 2016-07-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Comprehensive characterization of ligand-induced plasticity changes in a dimeric enzyme.
Febs J., 283, 2016
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5NFU
 | | The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1) in complex with LHSpTA peptide | | 分子名称: | Ac-LEU-HIS-SER-(TPO)-ALA, Serine/threonine-protein kinase PLK1 | | 著者 | Kunciw, D.L, Rossmann, M, De Fusco, C, Spring, D.R, Hyvonen, M. | | 登録日 | 2017-03-16 | | 公開日 | 2018-05-16 | | 最終更新日 | 2023-03-08 | | 実験手法 | X-RAY DIFFRACTION (1.809 Å) | | 主引用文献 | A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation.
Sci Rep, 9, 2019
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1POE
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1HNF
 | | CRYSTAL STRUCTURE OF THE EXTRACELLULAR REGION OF THE HUMAN CELL ADHESION MOLECULE CD2 AT 2.5 ANGSTROMS RESOLUTION | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CD2, SODIUM ION | | 著者 | Bodian, D.L, Jones, E.Y, Harlos, K, Stuart, D.I, Davis, S.J. | | 登録日 | 1994-08-10 | | 公開日 | 1995-02-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5 A resolution.
Structure, 2, 1994
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1QDV
 | | N-TERMINAL DOMAIN, VOLTAGE-GATED POTASSIUM CHANNEL KV1.2 RESIDUES 33-131 | | 分子名称: | KV1.2 VOLTAGE-GATED POTASSIUM CHANNEL | | 著者 | Minor Jr, D.L, Lin, Y.-F, Mobley, B.C, Yu, M, Jan, Y.N, Jan, L.Y, Berger, J.M. | | 登録日 | 1999-07-10 | | 公開日 | 2000-09-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel.
Cell(Cambridge,Mass.), 102, 2000
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