4QEO
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![BU of 4qeo by Molmil](/molmil-images/mine/4qeo) | crystal structure of KRYPTONITE in complex with mCHH DNA, H3(1-15) peptide and SAH | Descriptor: | DNA 5'-ACTGATGAGTACCAT-3', DNA 5'-GGTACT(5CM)ATCAGTAT-3', Histone H3, ... | Authors: | Du, J, Li, S, Patel, D.J. | Deposit date: | 2014-05-17 | Release date: | 2014-07-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE. Mol.Cell, 55, 2014
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4TTM
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![BU of 4ttm by Molmil](/molmil-images/mine/4ttm) | Racemic structure of kalata B1 (kB1) | Descriptor: | D-kalata B1, Kalata-B1 | Authors: | Wang, C.K, King, G.J, Craik, D.J. | Deposit date: | 2014-06-22 | Release date: | 2014-09-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9001 Å) | Cite: | Racemic and Quasi-Racemic X-ray Structures of Cyclic Disulfide-Rich Peptide Drug Scaffolds. Angew.Chem.Int.Ed.Engl., 53, 2014
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4RSD
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![BU of 4rsd by Molmil](/molmil-images/mine/4rsd) | STRUCTURE OF THE D121A VARIANT OF RIBONUCLEASE A | Descriptor: | ACETATE ION, CHLORIDE ION, RIBONUCLEASE A | Authors: | Schultz, L.W, Quirk, D.J, Raines, R.T. | Deposit date: | 1998-02-05 | Release date: | 1998-07-15 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | His...Asp catalytic dyad of ribonuclease A: structure and function of the wild-type, D121N, and D121A enzymes. Biochemistry, 37, 1998
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2KUK
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2KYO
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2KPR
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2OQF
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![BU of 2oqf by Molmil](/molmil-images/mine/2oqf) | Structure of a synthetic, non-natural analogue of RNase A: [N71K(Ade), D83A]RNase A | Descriptor: | Ribonuclease pancreatic | Authors: | Boerema, D.J, Tereshko, V.A, Zhang, J.L, He, C, Kent, S.B.H. | Deposit date: | 2007-01-31 | Release date: | 2008-02-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Design, Synthesis, and Characterization of Non-natural RNase A Analogues with Enhanced Second-step Catalytic Activity To be Published
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2OZY
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![BU of 2ozy by Molmil](/molmil-images/mine/2ozy) | Crystal structure of E.coli nrfB | Descriptor: | Cytochrome c-type protein nrfB, HEME C | Authors: | Clarke, T.A, Richardson, D.J, Hemmings, A.M. | Deposit date: | 2007-02-28 | Release date: | 2007-08-07 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | The crystal structure of the pentahaem c-type cytochrome NrfB and characterization of its solution-state interaction with the pentahaem nitrite reductase NrfA. Biochem.J., 406, 2007
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2ORX
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![BU of 2orx by Molmil](/molmil-images/mine/2orx) | Structural Basis for Ligand Binding and Heparin Mediated Activation of Neuropilin | Descriptor: | Neuropilin-1 | Authors: | Vander Kooi, C.W, Jusino, M.A, Perman, B, Neau, D.B, Bellamy, H.D, Leahy, D.J. | Deposit date: | 2007-02-05 | Release date: | 2007-04-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for ligand and heparin binding to neuropilin B domains Proc.Natl.Acad.Sci.Usa, 104, 2007
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2M2Y
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![BU of 2m2y by Molmil](/molmil-images/mine/2m2y) | Solution structure of the antimicrobial peptide Btd-2[3,4] | Descriptor: | BTD-2[3,4] | Authors: | Conibear, A.C, Rosengren, K, Daly, N.L, Troiera Henriques, S, Craik, D.J. | Deposit date: | 2013-01-03 | Release date: | 2013-02-27 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity. J.Biol.Chem., 288, 2013
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2MN1
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![BU of 2mn1 by Molmil](/molmil-images/mine/2mn1) | Solution Structure of kalata B1[W23WW] | Descriptor: | kalata B1[W23WW] | Authors: | Henriques, S.T, Huang, Y.H, Chaousis, S, Wang, C.K, Craik, D.J. | Deposit date: | 2014-03-26 | Release date: | 2015-05-27 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting. Chembiochem, 15, 2014
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2M13
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![BU of 2m13 by Molmil](/molmil-images/mine/2m13) | The ZZ domain of cytoplasmic polyadenylation element binding protein 1 (CPEB1) | Descriptor: | Cytoplasmic polyadenylation element-binding protein 1, ZINC ION | Authors: | Lee, B.M, Merkel, D.J, Wells, S.B, Hilburn, B.C, Elazzouzi, F, Perez-Alvarado, G.C. | Deposit date: | 2012-11-14 | Release date: | 2013-04-03 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The C-Terminal Region of Cytoplasmic Polyadenylation Element Binding Protein Is a ZZ Domain with Potential for Protein-Protein Interactions. J.Mol.Biol., 425, 2013
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2M77
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![BU of 2m77 by Molmil](/molmil-images/mine/2m77) | [Asp2]RTD-1 | Descriptor: | [Asp2]RTD-1 | Authors: | Conibear, A.C, Bochen, A, Rosengren, K, Kessler, H, Craik, D.J. | Deposit date: | 2013-04-18 | Release date: | 2014-02-05 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Cyclic Cystine Ladder of Theta-Defensins as a Stable, Bifunctional Scaffold: A Proof-of-Concept Study Using the Integrin-Binding RGD Motif Chembiochem, 15, 2014
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2MFA
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![BU of 2mfa by Molmil](/molmil-images/mine/2mfa) | Mambalgin-2 | Descriptor: | Mambalgin-2 | Authors: | Schroeder, C.I, Rash, L.D, Vila-Farres, X, Rosengren, K.J, Mobli, M, King, G.F, Alewood, P.F, Craik, D.J, Durek, T. | Deposit date: | 2013-10-08 | Release date: | 2014-01-01 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2. Angew.Chem.Int.Ed.Engl., 53, 2014
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2LYF
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2M98
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2LYE
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![BU of 2lye by Molmil](/molmil-images/mine/2lye) | High resolution NMR solution structure of a symmetrical theta-defensin, BTD-2 | Descriptor: | BTD-2 | Authors: | Conibear, A.C, Rosengren, K, Harvey, P.J, Craik, D.J. | Deposit date: | 2012-09-18 | Release date: | 2012-11-28 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural characterization of the cyclic cystine ladder motif of theta-defensins. Biochemistry, 51, 2012
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2P8Z
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![BU of 2p8z by Molmil](/molmil-images/mine/2p8z) | Fitted structure of ADPR-eEF2 in the 80S:ADPR-eEF2:GDPNP:sordarin cryo-EM reconstruction | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, Elongation factor Tu-B, ... | Authors: | Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J. | Deposit date: | 2007-03-23 | Release date: | 2007-05-08 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (8.9 Å) | Cite: | Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation. Embo J., 26, 2007
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2KGG
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2KHB
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2K7O
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![BU of 2k7o by Molmil](/molmil-images/mine/2k7o) | Ca2+-S100B, refined with RDCs | Descriptor: | CALCIUM ION, Protein S100-B | Authors: | Wright, N.T, Inman, K.G, Levine, J.A, Weber, D.J. | Deposit date: | 2008-08-17 | Release date: | 2008-11-18 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Refinement of the solution structure and dynamic properties of Ca(2+)-bound rat S100B. J.Biomol.Nmr, 42, 2008
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2KF3
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2KF5
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2P8W
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![BU of 2p8w by Molmil](/molmil-images/mine/2p8w) | Fitted structure of eEF2 in the 80S:eEF2:GDPNP cryo-EM reconstruction | Descriptor: | Elongation factor 2, Elongation factor Tu-B, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J. | Deposit date: | 2007-03-23 | Release date: | 2007-05-08 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (11.3 Å) | Cite: | Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation. Embo J., 26, 2007
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2OXM
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![BU of 2oxm by Molmil](/molmil-images/mine/2oxm) | Crystal structure of a UNG2/modified DNA complex that represent a stabilized short-lived extrahelical state in ezymatic DNA base flipping | Descriptor: | DNA (5'-D(*AP*AP*AP*GP*AP*TP*(4MF)P*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*AP*TP*CP*TP*T)-3'), Uracil-DNA glycosylase | Authors: | Bianchet, M.A, Krosky, D.J, Stivers, J.T, Amzel, L.M. | Deposit date: | 2007-02-20 | Release date: | 2007-10-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Enzymatic capture of an extrahelical thymine in the search for uracil in DNA. Nature, 449, 2007
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