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PDB: 2999 件

3L6G
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Crystal structure of lactococcal OpuAC in its open conformation
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Betaine ABC transporter permease and substrate binding protein
著者Berntsson, R.P.A, Wolters, J.C, Gul, N, Karasawa, A, Thunnissen, A.M.W.H, Slotboom, D.J, Poolman, B.
登録日2009-12-23
公開日2010-05-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ligand binding and crystal structures of the substrate-binding domain of the ABC transporter OpuA.
Plos One, 5, 2010
5J5S
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Src kinase in complex with a sulfonamide inhibitor
分子名称: N-{4-[8-amino-3-(propan-2-yl)imidazo[1,5-a]pyrazin-1-yl]naphthalen-1-yl}-N'-[3-(trifluoromethyl)phenyl]urea, Proto-oncogene tyrosine-protein kinase Src
著者Lebedev, I, Feldman, H.C, Georghiou, G, Maly, D.J, Seeliger, M.
登録日2016-04-03
公開日2016-06-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.153 Å)
主引用文献Structural and Functional Analysis of the Allosteric Modulation of IRE1a with ATP-Competitive Kinase Inhibitors
To Be Published
3LSR
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Crystal structure of DesT in complex with duplex DNA
分子名称: DNA (27-MER), DesT, SULFATE ION
著者Miller, D.J, White, S.W.
登録日2010-02-12
公開日2010-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural basis for the transcriptional regulation of membrane lipid homeostasis.
Nat.Struct.Mol.Biol., 17, 2010
3LK0
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X-ray structure of bovine SC0067,Ca(2+)-S100B
分子名称: 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, CALCIUM ION, Protein S100-B
著者Charpentier, T.H, Weber, D.J, Wilder, P.W.
登録日2010-01-26
公開日2010-12-29
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction.
Int J High Throughput Screen, 2010, 2010
3LSP
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Crystal Structure of DesT bound to desCB promoter and oleoyl-CoA
分子名称: DNA (5'-D(*TP*CP*AP*AP*TP*CP*GP*AP*GP*TP*CP*AP*AP*CP*AP*AP*GP*CP*GP*TP*TP*CP*AP*CP*TP*GP*AP*TP*GP*TP*A)-3'), DNA (5'-D(*TP*TP*AP*CP*AP*TP*CP*AP*GP*TP*GP*AP*AP*CP*GP*CP*TP*TP*GP*TP*TP*GP*AP*CP*TP*CP*GP*AP*TP*TP*G)-3'), DesT, ...
著者Miller, D.J, White, S.W.
登録日2010-02-12
公開日2010-08-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Structural basis for the transcriptional regulation of membrane lipid homeostasis.
Nat.Struct.Mol.Biol., 17, 2010
5IX1
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Crystal structure of mouse Morc3 ATPase-CW cassette in complex with AMPPNP and H3K4me3 peptide
分子名称: MAGNESIUM ION, MORC family CW-type zinc finger protein 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Li, S, Du, J, Patel, D.J.
登録日2016-03-23
公開日2016-08-17
最終更新日2016-09-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin
Proc.Natl.Acad.Sci.USA, 113, 2016
5JZL
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The Structure of Monomeric Ultra Stable Green Fluorescent Protein
分子名称: CHLORIDE ION, Green fluorescent protein, SODIUM ION
著者Gunn, N.J, Yong, K.J, Scott, D.J, Griffin, M.D.W.
登録日2016-05-17
公開日2017-12-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Novel Ultra-Stable, Monomeric Green Fluorescent Protein For Direct Volumetric Imaging of Whole Organs Using CLARITY.
Sci Rep, 8, 2018
3JBC
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Complex of Poliovirus with VHH PVSP29F
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Strauss, M, Schotte, L, Thys, B, Filman, D.J, Hogle, J.M.
登録日2015-08-26
公開日2016-01-27
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Five of Five VHHs Neutralizing Poliovirus Bind the Receptor-Binding Site.
J.Virol., 90, 2016
3JBG
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Complex of poliovirus with VHH PVSS21E
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Strauss, M, Schotte, L, Thys, B, Filman, D.J, Hogle, J.M.
登録日2015-08-26
公開日2016-01-27
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Five of Five VHHs Neutralizing Poliovirus Bind the Receptor-Binding Site.
J.Virol., 90, 2016
3K8D
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Crystal structure of E. coli lipopolysaccharide specific CMP-KDO synthetase in complex with CTP and 2-deoxy-Kdo
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, 3-deoxy-manno-octulosonate cytidylyltransferase, CYTIDINE-5'-TRIPHOSPHATE, ...
著者Heyes, D.J, Levy, C.W, Lafite, P, Scrutton, N.S, Leys, D.
登録日2009-10-14
公開日2009-11-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-based mechanism of CMP-2-keto-3-deoxymanno-octulonic acid synthetase: convergent evolution of a sugar-activating enzyme with DNA/RNA polymerases
J.Biol.Chem., 284, 2009
3J9F
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Poliovirus complexed with soluble, deglycosylated poliovirus receptor (Pvr) at 4 degrees C
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ...
著者Strauss, M, Filman, D.J, Belnap, D.M, Cheng, N, Noel, R.T, Hogle, J.M.
登録日2015-01-15
公開日2015-02-11
最終更新日2022-12-21
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Nectin-Like Interactions between Poliovirus and Its Receptor Trigger Conformational Changes Associated with Cell Entry.
J.Virol., 89, 2015
5JSZ
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Folate ECF transporter: apo state
分子名称: Conserved hypothetical membrane protein, Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, ...
著者Swier, L.J.Y.M, Guskov, A, Slotboom, D.J.
登録日2016-05-09
公開日2016-05-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.004 Å)
主引用文献Structural insight in the toppling mechanism of an energy-coupling factor transporter.
Nat Commun, 7, 2016
5JP2
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Fcho1 Mu homology domain (Danio Rerio) with bound Eps15 peptide
分子名称: Epidermal growth factor receptor substrate 15, F-BAR domain only protein 1, ZINC ION
著者McCoy, A.J, Wrobel, A, Owen, D.J.
登録日2016-05-03
公開日2016-06-08
最終更新日2016-06-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Transient Fcho1/2Eps15/RAP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.
Dev.Cell, 37, 2016
5K8Q
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Crystal Structure of Calcium-loaded Calmodulin in complex with STRA6 CaMBP2-site peptide.
分子名称: CALCIUM ION, Calmodulin, IMIDAZOLE, ...
著者Stowe, S.D, Clarke, O.B, Cavalier, M.C, Godoy-Ruiz, R, Mancia, F, Weber, D.J.
登録日2016-05-30
公開日2016-08-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.739 Å)
主引用文献Structure of the STRA6 receptor for retinol uptake.
Science, 353, 2016
5IW4
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Crystal structure of E. coli NudC in complex with NAD
分子名称: NADH pyrophosphatase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
著者Li, S, Du, J, Patel, D.J.
登録日2016-03-22
公開日2016-07-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and function of the bacterial decapping enzyme NudC.
Nat.Chem.Biol., 12, 2016
5IXA
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HCMV DNA polymerase processivity subunit UL44 at neutral pH and low salt
分子名称: DNA polymerase processivity factor
著者Chen, H, Coen, D.M, Hogle, J.M, Filman, D.J.
登録日2016-03-23
公開日2016-11-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.684 Å)
主引用文献A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions.
ACS Infect Dis, 3, 2017
5JZK
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The Structure of Ultra Stable Green Fluorescent Protein
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ...
著者Yong, K.J, Gunn, N.J, Scott, D.J, Griffin, M.D.W.
登録日2016-05-17
公開日2017-12-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Novel Ultra-Stable, Monomeric Green Fluorescent Protein For Direct Volumetric Imaging of Whole Organs Using CLARITY.
Sci Rep, 8, 2018
3KT7
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Crystal structure of Tpa1 from Saccharomyces cerevisiae, a component of the messenger ribonucleoprotein complex
分子名称: 2-OXOGLUTARIC ACID, FE (III) ION, GLYCEROL, ...
著者Kim, H.S, Kim, H.L, Kim, K.H, Kim, D.J, Lee, S.J, Yoon, J.Y, Yoon, H.J, Lee, H.Y, Park, S.B, Kim, S.-J, Lee, J.Y, Suh, S.W.
登録日2009-11-24
公開日2010-01-19
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Crystal structure of Tpa1 from Saccharomyces cerevisiae, a component of the messenger ribonucleoprotein complex
Nucleic Acids Res., 38, 2010
5K9N
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Structural and Mechanistic Analysis of Drosophila melanogaster Polyamine N acetyltransferase, an enzyme that Catalyzes the Formation of N acetylagmatine
分子名称: Polyamine N acetyltransferase
著者Dempsey, D.R, Nichols, D.A, Battistini, M.R, Pemberton, O, Ospina, S.R, Zhang, X, Carpenter, A.-M, Chen, Y, Merkler, D.J.
登録日2016-06-01
公開日2017-06-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Mechanistic Analysis of Drosophila melanogaster Agmatine N-Acetyltransferase, an Enzyme that Catalyzes the Formation of N-Acetylagmatine.
Sci Rep, 7, 2017
1CLO
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ANTI-CARCINOEMBRYONIC ANTIGEN MONOCLONAL ANTIBODY A5B7
分子名称: A5B7 MONOCLONAL ANTIBODY
著者Banfield, M.J, King, D.J, Mountain, A, Brady, R.L.
登録日1996-05-01
公開日1997-05-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs.
Proteins, 29, 1997
5JDX
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PigG holo
分子名称: 4'-PHOSPHOPANTETHEINE, Putative peptidyl carrier protein
著者Jaremko, M.J, Lee, D.J, Burkart, M.D.
登録日2016-04-17
公開日2017-08-23
最終更新日2019-12-04
実験手法SOLUTION NMR
主引用文献PigG holo
To Be Published
3MJX
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Crystal structure of myosin-2 motor domain in complex with ADP-Metavanadate and blebbistatin
分子名称: (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, ADP METAVANADATE, MAGNESIUM ION, ...
著者Fedorov, R, Baruch, P, Bauer, S, Manstein, D.J.
登録日2010-04-13
公開日2011-04-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The mechanism of pentabromopseudilin inhibition of myosin motor activity.
Nat.Struct.Mol.Biol., 16, 2009
3LML
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Crystal Structure of the sheath tail protein Lin1278 from Listeria innocua, Northeast Structural Genomics Consortium Target LkR115
分子名称: Lin1278 protein
著者Forouhar, F, Neely, H, Seetharaman, J, Mao, M, Xiao, R, Patel, D.J, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2010-01-31
公開日2010-03-09
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Northeast Structural Genomics Consortium Target LkR115
To be Published
3LQJ
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Crystal structure of MLL1 PHD3-Bromo complexed with H3(1-9)K4me3 peptide
分子名称: Histone H3, MLL1 PHD3-Bromo, ZINC ION
著者Wang, Z, Patel, D.J.
登録日2010-02-09
公開日2010-07-07
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell(Cambridge,Mass.), 141, 2010
3L6H
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Crystal structure of lactococcal OpuAC in its closed-liganded conformation complexed with glycine betaine
分子名称: Betaine ABC transporter permease and substrate binding protein, CHLORIDE ION, TRIMETHYL GLYCINE
著者Berntsson, R.P.A, Wolters, J.C, Gul, N, Karasawa, A, Thunnissen, A.M.W.H, Slotboom, D.J, Poolman, B.
登録日2009-12-23
公開日2010-05-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ligand binding and crystal structures of the substrate-binding domain of the ABC transporter OpuA.
Plos One, 5, 2010

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