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PDB: 2999 件

4QEO
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BU of 4qeo by Molmil
crystal structure of KRYPTONITE in complex with mCHH DNA, H3(1-15) peptide and SAH
分子名称: DNA 5'-ACTGATGAGTACCAT-3', DNA 5'-GGTACT(5CM)ATCAGTAT-3', Histone H3, ...
著者Du, J, Li, S, Patel, D.J.
登録日2014-05-17
公開日2014-07-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of DNA Methylation-Directed Histone Methylation by KRYPTONITE.
Mol.Cell, 55, 2014
4TTM
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BU of 4ttm by Molmil
Racemic structure of kalata B1 (kB1)
分子名称: D-kalata B1, Kalata-B1
著者Wang, C.K, King, G.J, Craik, D.J.
登録日2014-06-22
公開日2014-09-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9001 Å)
主引用文献Racemic and Quasi-Racemic X-ray Structures of Cyclic Disulfide-Rich Peptide Drug Scaffolds.
Angew.Chem.Int.Ed.Engl., 53, 2014
4RSD
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BU of 4rsd by Molmil
STRUCTURE OF THE D121A VARIANT OF RIBONUCLEASE A
分子名称: ACETATE ION, CHLORIDE ION, RIBONUCLEASE A
著者Schultz, L.W, Quirk, D.J, Raines, R.T.
登録日1998-02-05
公開日1998-07-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献His...Asp catalytic dyad of ribonuclease A: structure and function of the wild-type, D121N, and D121A enzymes.
Biochemistry, 37, 1998
2KUK
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BU of 2kuk by Molmil
Solution structure of vhl-2
分子名称: Leaf cyclotide 2
著者Daly, N.L, Chen, B, Nguyencong, P, Craik, D.J.
登録日2010-02-18
公開日2011-01-12
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure and Activity of the Leaf-Specific Cyclotide vhl-2
AUST.J.CHEM., 63, 2010
2KYO
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BU of 2kyo by Molmil
Dimeric human ckit-2 proto-oncogene promoter quadruplex DNA NMR, 10 structures
分子名称: 5'-D(*CP*GP*GP*GP*CP*GP*GP*GP*CP*GP*CP*GP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3'
著者Kuryavyi, V, Phan, A.T, Patel, D.J.
登録日2010-06-05
公開日2010-06-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter.
Nucleic Acids Res., 38, 2010
2KPR
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BU of 2kpr by Molmil
Monomeric intronic human chl1 gene quadruplex DNA NMR, 17 structures
分子名称: 5'-D(*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*GP*GP*GP*TP*GP*GP*GP*T)-3'
著者Kuryavyi, V, Patel, D.J.
登録日2009-10-19
公開日2010-03-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of a Unique G-Quadruplex Scaffold Adopted by a Guanosine-Rich Human Intronic Sequence.
Structure, 18, 2010
2OQF
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Structure of a synthetic, non-natural analogue of RNase A: [N71K(Ade), D83A]RNase A
分子名称: Ribonuclease pancreatic
著者Boerema, D.J, Tereshko, V.A, Zhang, J.L, He, C, Kent, S.B.H.
登録日2007-01-31
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Design, Synthesis, and Characterization of Non-natural RNase A Analogues with Enhanced Second-step Catalytic Activity
To be Published
2OZY
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BU of 2ozy by Molmil
Crystal structure of E.coli nrfB
分子名称: Cytochrome c-type protein nrfB, HEME C
著者Clarke, T.A, Richardson, D.J, Hemmings, A.M.
登録日2007-02-28
公開日2007-08-07
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献The crystal structure of the pentahaem c-type cytochrome NrfB and characterization of its solution-state interaction with the pentahaem nitrite reductase NrfA.
Biochem.J., 406, 2007
2ORX
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BU of 2orx by Molmil
Structural Basis for Ligand Binding and Heparin Mediated Activation of Neuropilin
分子名称: Neuropilin-1
著者Vander Kooi, C.W, Jusino, M.A, Perman, B, Neau, D.B, Bellamy, H.D, Leahy, D.J.
登録日2007-02-05
公開日2007-04-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for ligand and heparin binding to neuropilin B domains
Proc.Natl.Acad.Sci.Usa, 104, 2007
2M2Y
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BU of 2m2y by Molmil
Solution structure of the antimicrobial peptide Btd-2[3,4]
分子名称: BTD-2[3,4]
著者Conibear, A.C, Rosengren, K, Daly, N.L, Troiera Henriques, S, Craik, D.J.
登録日2013-01-03
公開日2013-02-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity.
J.Biol.Chem., 288, 2013
2MN1
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Solution Structure of kalata B1[W23WW]
分子名称: kalata B1[W23WW]
著者Henriques, S.T, Huang, Y.H, Chaousis, S, Wang, C.K, Craik, D.J.
登録日2014-03-26
公開日2015-05-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting.
Chembiochem, 15, 2014
2M13
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BU of 2m13 by Molmil
The ZZ domain of cytoplasmic polyadenylation element binding protein 1 (CPEB1)
分子名称: Cytoplasmic polyadenylation element-binding protein 1, ZINC ION
著者Lee, B.M, Merkel, D.J, Wells, S.B, Hilburn, B.C, Elazzouzi, F, Perez-Alvarado, G.C.
登録日2012-11-14
公開日2013-04-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The C-Terminal Region of Cytoplasmic Polyadenylation Element Binding Protein Is a ZZ Domain with Potential for Protein-Protein Interactions.
J.Mol.Biol., 425, 2013
2M77
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BU of 2m77 by Molmil
[Asp2]RTD-1
分子名称: [Asp2]RTD-1
著者Conibear, A.C, Bochen, A, Rosengren, K, Kessler, H, Craik, D.J.
登録日2013-04-18
公開日2014-02-05
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Cyclic Cystine Ladder of Theta-Defensins as a Stable, Bifunctional Scaffold: A Proof-of-Concept Study Using the Integrin-Binding RGD Motif
Chembiochem, 15, 2014
2MFA
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BU of 2mfa by Molmil
Mambalgin-2
分子名称: Mambalgin-2
著者Schroeder, C.I, Rash, L.D, Vila-Farres, X, Rosengren, K.J, Mobli, M, King, G.F, Alewood, P.F, Craik, D.J, Durek, T.
登録日2013-10-08
公開日2014-01-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2.
Angew.Chem.Int.Ed.Engl., 53, 2014
2LYF
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BU of 2lyf by Molmil
High resolution NMR solution structure of the theta-defensin RTD-1
分子名称: RTD-1
著者Conibear, A.C, Rosengren, K, Harvey, P.J, Craik, D.J.
登録日2012-09-18
公開日2012-11-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural characterization of the cyclic cystine ladder motif of theta-defensins.
Biochemistry, 51, 2012
2M98
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BU of 2m98 by Molmil
NMR Structure of BeF3 Activated Sma0114
分子名称: BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, Two-component response regulator
著者Sheftic, S.R, Gage, D.J, Alexandrescu, A.T.
登録日2013-06-04
公開日2014-01-29
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR Structure of the HWE Kinase Associated Response Regulator Sma0114 in Its Activated State.
Biochemistry, 53, 2014
2LYE
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BU of 2lye by Molmil
High resolution NMR solution structure of a symmetrical theta-defensin, BTD-2
分子名称: BTD-2
著者Conibear, A.C, Rosengren, K, Harvey, P.J, Craik, D.J.
登録日2012-09-18
公開日2012-11-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural characterization of the cyclic cystine ladder motif of theta-defensins.
Biochemistry, 51, 2012
2P8Z
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BU of 2p8z by Molmil
Fitted structure of ADPR-eEF2 in the 80S:ADPR-eEF2:GDPNP:sordarin cryo-EM reconstruction
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, Elongation factor Tu-B, ...
著者Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J.
登録日2007-03-23
公開日2007-05-08
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (8.9 Å)
主引用文献Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation.
Embo J., 26, 2007
2KGG
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BU of 2kgg by Molmil
Solution Structure of JARID1A C-terminal PHD finger
分子名称: Histone demethylase JARID1A, ZINC ION
著者Song, J, Wang, Z, Patel, D.J.
登録日2009-03-11
公開日2009-05-05
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
2KHB
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BU of 2khb by Molmil
Solution structure of linear kalata B1 (loop 6)
分子名称: Kalata-B1
著者Wang, C.K, Craik, D.J.
登録日2009-04-01
公開日2010-03-31
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Cyclotides insert into lipid bilayers to form membrane pores and destabilize the membrane
To be Published
2K7O
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BU of 2k7o by Molmil
Ca2+-S100B, refined with RDCs
分子名称: CALCIUM ION, Protein S100-B
著者Wright, N.T, Inman, K.G, Levine, J.A, Weber, D.J.
登録日2008-08-17
公開日2008-11-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Refinement of the solution structure and dynamic properties of Ca(2+)-bound rat S100B.
J.Biomol.Nmr, 42, 2008
2KF3
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BU of 2kf3 by Molmil
Barnase, low pressure reference NMR structure
分子名称: Ribonuclease
著者Williamson, M.P, Wilton, D.J.
登録日2009-02-11
公開日2009-12-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Pressure-dependent structure changes in barnase on ligand binding reveal intermediate rate fluctuations.
Biophys.J., 97, 2009
2KF5
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Barnase bound to d(CGAC), low pressure
分子名称: Ribonuclease
著者Williamson, M.P, Wilton, D.J.
登録日2009-02-11
公開日2009-12-08
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Pressure-dependent structure changes in barnase on ligand binding reveal intermediate rate fluctuations.
Biophys.J., 97, 2009
2P8W
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BU of 2p8w by Molmil
Fitted structure of eEF2 in the 80S:eEF2:GDPNP cryo-EM reconstruction
分子名称: Elongation factor 2, Elongation factor Tu-B, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J.
登録日2007-03-23
公開日2007-05-08
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (11.3 Å)
主引用文献Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation.
Embo J., 26, 2007
2OXM
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BU of 2oxm by Molmil
Crystal structure of a UNG2/modified DNA complex that represent a stabilized short-lived extrahelical state in ezymatic DNA base flipping
分子名称: DNA (5'-D(*AP*AP*AP*GP*AP*TP*(4MF)P*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*AP*TP*CP*TP*T)-3'), Uracil-DNA glycosylase
著者Bianchet, M.A, Krosky, D.J, Stivers, J.T, Amzel, L.M.
登録日2007-02-20
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Enzymatic capture of an extrahelical thymine in the search for uracil in DNA.
Nature, 449, 2007

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