1A8N
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![BU of 1a8n by Molmil](/molmil-images/mine/1a8n) | SOLUTION STRUCTURE OF A NA+ CATION STABILIZED DNA QUADRUPLEX CONTAINING G.G.G.G AND G.C.G.C TETRADS FORMED BY G-G-G-C REPEATS OBSERVED IN AAV AND HUMAN CHROMOSOME 19, NMR, 8 STRUCTURES | 分子名称: | DNA QUADRUPLEX CONTAINING G.G.G.G AND G.C.G.C TETRADS | 著者 | Kettani, A, Bouaziz, S, Gorin, A, Zhao, H, Jones, R, Patel, D.J. | 登録日 | 1998-03-27 | 公開日 | 1998-10-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a Na cation stabilized DNA quadruplex containing G.G.G.G and G.C.G.C tetrads formed by G-G-G-C repeats observed in adeno-associated viral DNA. J.Mol.Biol., 282, 1998
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6BOG
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![BU of 6bog by Molmil](/molmil-images/mine/6bog) | Crystal structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription | 分子名称: | RNA polymerase-associated protein RapA, SULFATE ION | 著者 | Shaw, G.X, Gan, J, Zhou, Y.N, Zhang, R, Joachimiak, A, Jin, D.J, Ji, X. | 登録日 | 2017-11-20 | 公開日 | 2017-12-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.205 Å) | 主引用文献 | Structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription. Structure, 16, 2008
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3BS1
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![BU of 3bs1 by Molmil](/molmil-images/mine/3bs1) | Structure of the Staphylococcus aureus AgrA LytTR Domain Bound to DNA Reveals a Beta Fold with a Novel Mode of Binding | 分子名称: | Accessory gene regulator protein A, DNA (5'-D(*DAP*DAP*(BRU)P*DAP*DCP*DTP*DTP*DAP*DAP*DCP*DTP*DGP*DTP*DTP*DAP*DA)-3'), DNA (5'-D(*DTP*DTP*DTP*DAP*DAP*DCP*DAP*DGP*DTP*DTP*DAP*DAP*DGP*(BRU)P*DAP*DT)-3'), ... | 著者 | Sidote, D.J, Barbieri, C, Wu, T, Stock, A.M. | 登録日 | 2007-12-21 | 公開日 | 2008-04-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structure of the Staphylococcus aureus AgrA LytTR Domain Bound to DNA Reveals a Beta Fold with an Unusual Mode of Binding. Structure, 16, 2008
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6ANV
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![BU of 6anv by Molmil](/molmil-images/mine/6anv) | Crystal structure of anti-CRISPR protein AcrF1 | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | 著者 | Yang, H, Patel, D.J. | 登録日 | 2017-08-14 | 公開日 | 2017-10-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.265 Å) | 主引用文献 | Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. Cell, 171, 2017
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6AWL
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![BU of 6awl by Molmil](/molmil-images/mine/6awl) | Crystal structure of human Coq9 | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, Ubiquinone biosynthesis protein COQ9, ... | 著者 | Bingman, C.A, Lohman, D.C, Smith, R.W, Pagliarini, D.J, Mitochondrial Protein Partnership (MPP) | 登録日 | 2017-09-05 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis. Mol. Cell, 73, 2019
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6B89
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![BU of 6b89 by Molmil](/molmil-images/mine/6b89) | E. coli LptB in complex with ADP and novobiocin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lipopolysaccharide export system ATP-binding protein LptB, MAGNESIUM ION, ... | 著者 | May, J.M, Lazarus, M.B, Sherman, D.J, Owens, T.W, Mandler, M.D, Kahne, D.K. | 登録日 | 2017-10-05 | 公開日 | 2017-12-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Antibiotic Novobiocin Binds and Activates the ATPase That Powers Lipopolysaccharide Transport. J. Am. Chem. Soc., 139, 2017
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6ASP
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![BU of 6asp by Molmil](/molmil-images/mine/6asp) | Structure of Grp94 with methyl 3-chloro-2-(2-(1-(2-ethoxybenzyl)-1 H-imidazol-2-yl)ethyl)-4,6-dihydroxybenzoate, a Grp94-selective inhibitor and promising therapeutic lead for treating myocilin-associated glaucoma | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Endoplasmin, GLYCEROL, ... | 著者 | Huard, D.J.E, Lieberman, R.L. | 登録日 | 2017-08-25 | 公開日 | 2018-04-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.696 Å) | 主引用文献 | Trifunctional High-Throughput Screen Identifies Promising Scaffold To Inhibit Grp94 and Treat Myocilin-Associated Glaucoma. ACS Chem. Biol., 13, 2018
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1AY1
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![BU of 1ay1 by Molmil](/molmil-images/mine/1ay1) | ANTI TAQ FAB TP7 | 分子名称: | TP7 FAB | 著者 | Murali, R, Helmer-Citterich, M, Sharkey, D.J, Scalice, E.R, Daiss, J.L, Sullivan, M.A, Murthy, H.M.K. | 登録日 | 1997-11-13 | 公開日 | 1998-05-13 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural studies on an inhibitory antibody against Thermus aquaticus DNA polymerase suggest mode of inhibition. Protein Eng., 11, 1998
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1B3P
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![BU of 1b3p by Molmil](/molmil-images/mine/1b3p) | 5'-D(*GP*GP*AP*GP*GP*AP*T)-3' | 分子名称: | DNA (5'-D(*GP*GP*AP*GP*GP*AP*T)-3') | 著者 | Kettani, A, Bouaziz, S, Skripkin, E, Majumdar, A, Wang, W, Jones, R.A, Patel, D.J. | 登録日 | 1998-12-14 | 公開日 | 1999-08-31 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Interlocked mismatch-aligned arrowhead DNA motifs. Structure Fold.Des., 7, 1999
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5T0P
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![BU of 5t0p by Molmil](/molmil-images/mine/5t0p) | c-Src kinase domain in complex with Rao-IV-151 | 分子名称: | (2E)-3-[4-amino-5-(4-chlorophenyl)-7-(2-methoxyethyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-cyano-N-(propan-2-yl)prop-2-enamide, Proto-oncogene tyrosine-protein kinase Src | 著者 | Dieter, E.M, Merritt, E.A, Maly, D.J. | 登録日 | 2016-08-16 | 公開日 | 2017-08-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A chemical genetic method for conformation-selective kinase inhibition To Be Published
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1B43
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![BU of 1b43 by Molmil](/molmil-images/mine/1b43) | FEN-1 FROM P. FURIOSUS | 分子名称: | PROTEIN (FEN-1) | 著者 | Hosfield, D.J, Mol, C.D, Shen, B, Tainer, J.A. | 登録日 | 1999-01-05 | 公開日 | 2000-01-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity. Cell(Cambridge,Mass.), 95, 1998
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1BA6
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1AT0
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![BU of 1at0 by Molmil](/molmil-images/mine/1at0) | 17-kDA fragment of hedgehog C-terminal autoprocessing domain | 分子名称: | 17-HEDGEHOG | 著者 | Hall, T.M.T, Porter, J.A, Young, K.E, Koonin, E.V, Beachy, P.A, Leahy, D.J. | 登録日 | 1997-08-15 | 公開日 | 1997-11-12 | 最終更新日 | 2017-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins. Cell(Cambridge,Mass.), 91, 1997
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4PDZ
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![BU of 4pdz by Molmil](/molmil-images/mine/4pdz) | Crystal Structure of Calcium-loaded S100B bound to SBi4172 | 分子名称: | 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium, CALCIUM ION, Protein S100-B | 著者 | Cavalier, M.C, Pierce, A.D, Wilder, P.T, Neau, D, Toth, E.A, Weber, D.J. | 登録日 | 2014-04-22 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Covalent Small Molecule Inhibitors of Ca(2+)-Bound S100B. Biochemistry, 53, 2014
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4PE4
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![BU of 4pe4 by Molmil](/molmil-images/mine/4pe4) | Crystal Structure of Calcium-loaded S100B bound to SC1475 | 分子名称: | 2,3-dimethoxy-5-[(1S)-1-phenylpropyl]benzene-1,4-diol, CALCIUM ION, Protein S100-B | 著者 | Cavalier, M.C, Pierce, A.D, Wilder, P.T, Neau, D, Toth, E.A, Weber, D.J. | 登録日 | 2014-04-22 | 公開日 | 2014-10-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.178 Å) | 主引用文献 | Covalent Small Molecule Inhibitors of Ca(2+)-Bound S100B. Biochemistry, 53, 2014
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1PIK
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![BU of 1pik by Molmil](/molmil-images/mine/1pik) | ESPERAMICIN A1-DNA COMPLEX, NMR, 4 STRUCTURES | 分子名称: | 2,4-dideoxy-3-O-methyl-4-(propan-2-ylamino)-alpha-L-threo-pentopyranose-(1-2)-4-amino-4,6-dideoxy-beta-D-glucopyranose, 2,6-dideoxy-4-S-methyl-4-thio-beta-D-ribo-hexopyranose, 2-deoxy-alpha-L-fucopyranose, ... | 著者 | Kumar, R.A, Ikemoto, N, Patel, D.J. | 登録日 | 1996-12-11 | 公開日 | 1997-03-12 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Esperamicin A1-DNA Complex J.Mol.Biol., 265, 1997
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1AXU
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![BU of 1axu by Molmil](/molmil-images/mine/1axu) | SOLUTION NMR STRUCTURE OF THE [AP]DG ADDUCT OPPOSITE DA IN A DNA DUPLEX, NMR, 9 STRUCTURES | 分子名称: | DNA DUPLEX D(CCATC-[AP]G-CTACC)D(GGTAGAGATGG), N-1-AMINOPYRENE | 著者 | Gu, Z, Gorin, A.A, Krishnasami, R, Hingerty, B.E, Basu, A.K, Broyde, S, Patel, D.J. | 登録日 | 1997-10-21 | 公開日 | 1998-07-01 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the N-(deoxyguanosin-8-yl)-1-aminopyrene ([AP]dG) adduct opposite dA in a DNA duplex. Biochemistry, 38, 1999
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1BA4
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![BU of 1ba4 by Molmil](/molmil-images/mine/1ba4) | THE SOLUTION STRUCTURE OF AMYLOID BETA-PEPTIDE (1-40) IN A WATER-MICELLE ENVIRONMENT. IS THE MEMBRANE-SPANNING DOMAIN WHERE WE THINK IT IS? NMR, 10 STRUCTURES | 分子名称: | AMYLOID BETA-PEPTIDE | 著者 | Coles, M, Bicknell, W, Watson, A.A, Fairlie, D.P, Craik, D.J. | 登録日 | 1998-04-07 | 公開日 | 1998-06-17 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is? Biochemistry, 37, 1998
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3DWJ
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![BU of 3dwj by Molmil](/molmil-images/mine/3dwj) | Heme-proximal W188H mutant of inducible nitric oxide synthase | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, AMMONIUM ION, Nitric oxide synthase, ... | 著者 | Tejero, J, Biswas, A, Wang, Z.-Q, Haque, M.M, Hemann, C, Zweier, J.L, Page, R.C, Misra, S, Stuehr, D.J. | 登録日 | 2008-07-22 | 公開日 | 2008-09-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Stabilization and Characterization of a Heme-Oxy Reaction Intermediate in Inducible Nitric-oxide Synthase J.Biol.Chem., 283, 2008
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1ATJ
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![BU of 1atj by Molmil](/molmil-images/mine/1atj) | RECOMBINANT HORSERADISH PEROXIDASE C1A | 分子名称: | CALCIUM ION, PEROXIDASE C1A, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Gajhede, M, Schuller, D.J, Henriksen, A, Smith, A.T, Poulos, T.L. | 登録日 | 1997-08-14 | 公開日 | 1998-02-04 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure of horseradish peroxidase C at 2.15 A resolution. Nat.Struct.Biol., 4, 1997
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1AXL
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![BU of 1axl by Molmil](/molmil-images/mine/1axl) | SOLUTION CONFORMATION OF THE (-)-TRANS-ANTI-[BP]DG ADDUCT OPPOSITE A DELETION SITE IN DNA DUPLEX D(CCATC-[BP]G-CTACC)D(GGTAG--GATGG), NMR, 6 STRUCTURES | 分子名称: | 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, DNA DUPLEX D(CCATC-[BP]G-CTACC)D(GGTAG--GATGG) | 著者 | Feng, B, Gorin, A.A, Kolbanovskiy, A, Hingerty, B.E, Geacintov, N.E, Broyde, S, Patel, D.J. | 登録日 | 1997-10-16 | 公開日 | 1998-07-01 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove. Biochemistry, 36, 1997
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5SYS
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![BU of 5sys by Molmil](/molmil-images/mine/5sys) | c-Src V281C bound to N-[3-({6-[(1E)-2-cyano-3-(methylamino)-3-oxoprop-1-en-1-yl]-7-(2-methoxyethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethynyl)-4-methylphenyl]-3-(trifluoromethyl)benzamide inhibitor | 分子名称: | N-[3-({6-[(2S)-2-cyano-3-(methylamino)-3-oxopropyl]-7-(2-methoxyethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethynyl)-4-methylphenyl]-3-(trifluoromethyl)benzamide, Proto-oncogene tyrosine-protein kinase Src | 著者 | Dieter, E.M, Merritt, E.A, Maly, D.J. | 登録日 | 2016-08-11 | 公開日 | 2017-08-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A combined approach reveals a regulatory mechanism coupling Src's kinase activity, localization, and phosphotransferase-independent functions Mol.Cell, 2019
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5T1Z
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![BU of 5t1z by Molmil](/molmil-images/mine/5t1z) | Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Ethoxytriphenylethylene and GRIP Peptide | 分子名称: | 4,4'-[(1Z)-1-(4-ethoxyphenyl)but-1-ene-1,2-diyl]diphenol, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Fanning, S.W, Rajan, S.S, Maximov, P.Y, Abderrahman, B.H, Surojeet, S, Fernandes, D.J, Fan, P, Curpan, R.F, Greene, G.L, Jordan, V.C. | 登録日 | 2016-08-22 | 公開日 | 2017-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer. Mol. Pharmacol., 94, 2018
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5T1Y
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3D17
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![BU of 3d17 by Molmil](/molmil-images/mine/3d17) | A triply ligated crystal structure of relaxed state human hemoglobin | 分子名称: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | 著者 | Safo, M.K, Musayev, F.N, Jenkins, J, Abraham, D.J. | 登録日 | 2008-05-05 | 公開日 | 2008-06-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A triply ligated crystal structure of relaxed state human hemoglobin TO BE PUBLISHED
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