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PDB: 2998 件

3B4A
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T. tengcongensis glmS ribozyme with G40A mutation, bound to glucosamine-6-phosphate
分子名称: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, glmS ribozyme RNA, ...
著者Klein, D.J, Ferre-D'Amare, A.R.
登録日2007-10-23
公開日2007-12-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Essential Role of an Active-Site Guanine in glmS Ribozyme Catalysis.
J.Am.Chem.Soc., 129, 2007
1WLG
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Crystal structure of FlgE31, a major fragment of the hook protein
分子名称: Flagellar hook protein flgE
著者Samatey, F.A, Matsunami, H, Imada, K, Nagashima, S, Shaikh, T.R, Thomas, D.R, DeRosier, D.J, Kitao, A, Namba, K.
登録日2004-06-25
公開日2004-11-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the bacterial flagellar hook and implication for the molecular universal joint mechanism.
Nature, 431, 2004
5M7U
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Structure of human O-GlcNAc hydrolase with new iminocyclitol type inhibitor
分子名称: 2-[(2~{R},3~{S},4~{R},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)-1-[3-[3-(trifluoromethyl)phenyl]propyl]pyrrolidin-2-yl]-~{N}-methyl-ethanamide, Protein O-GlcNAcase
著者Roth, C, Chan, S, Offen, W.A, Hemsworth, G.R, Willems, L.I, King, D, Varghese, V, Britton, R, Vocadlo, D.J, Davies, G.J.
登録日2016-10-28
公開日2017-03-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and functional insight into human O-GlcNAcase.
Nat. Chem. Biol., 13, 2017
1M9R
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BU of 1m9r by Molmil
human endothelial nitric oxide synthase with 3-Bromo-7-Nitroindazole bound
分子名称: 3-BROMO-7-NITROINDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ZINC ION, ...
著者Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D.
登録日2002-07-29
公開日2002-08-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency
Biochemistry, 41, 2002
5MBT
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BU of 5mbt by Molmil
CeuE (H227L, Y288F variant) a periplasmic protein from Campylobacter jejuni
分子名称: Enterochelin uptake periplasmic binding protein
著者Wilde, E.J, Blagova, E.V, Hughes, A, Raines, D.J, Moroz, O.V, Turkenburg, J.P, Duhme-Klair, A.-K, Wilson, K.S.
登録日2016-11-08
公開日2017-04-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length.
Sci Rep, 7, 2017
5MEK
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BU of 5mek by Molmil
Sulphotransferase-18 from Arabidopsis thaliana in complex with 3'-phosphoadenosine 5'-phosphate (PAP)
分子名称: 1,2-ETHANEDIOL, ADENOSINE-3'-5'-DIPHOSPHATE, Cytosolic sulfotransferase 18, ...
著者Hirschmann, F, Krause, F, Baruch, P, Chizhov, I, Mueller, J.W, Manstein, D.J, Papenbrock, J, Fedorov, R.
登録日2016-11-15
公開日2017-07-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural and biochemical studies of sulphotransferase 18 from Arabidopsis thaliana explain its substrate specificity and reaction mechanism.
Sci Rep, 7, 2017
1W9P
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Specificity and affinity of natural product cyclopentapeptide inhibitors against Aspergillus fumigatus, human and bacterial chitinaseFra
分子名称: CHITINASE, SULFATE ION
著者Rao, F.V, Houston, D.R, Boot, R.G, Aerts, J.M.F.G, Hodkinson, M, Adams, D.J, Shiomi, K, Omura, S, Van Aalten, D.M.F.
登録日2004-10-15
公開日2004-10-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases
Chem.Biol., 12, 2005
1WB0
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specificity and affinity of natural product cyclopentapeptide inhibitor Argifin against human chitinase
分子名称: ARGIFIN, CHITOTRIOSIDASE 1, GLYCEROL, ...
著者Rao, F.V, Houston, D.R, Boot, R.G, Aerts, J.M.F.G, Hodkinson, M, Adams, D.J, Shiomi, K, Omura, S, Van Aalten, D.M.F.
登録日2004-10-29
公開日2005-01-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases
Chem.Biol., 12, 2005
3CNN
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BU of 3cnn by Molmil
GTP-bound structure of TM YlqF
分子名称: GUANOSINE-5'-TRIPHOSPHATE, Putative uncharacterized protein
著者Kim, D.J, Jang, J.Y, Yoon, H.-J, Suh, S.W.
登録日2008-03-26
公開日2008-06-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of YlqF, a circularly permuted GTPase: Implications for its GTPase activation in 50 S ribosomal subunit assembly
Proteins, 72, 2008
3CKE
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BU of 3cke by Molmil
Crystal structure of aristolochene synthase in complex with 12,13-difluorofarnesyl diphosphate
分子名称: (2E,6E)-12-fluoro-11-(fluoromethyl)-3,7-dimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, Aristolochene synthase, BETA-MERCAPTOETHANOL, ...
著者Shishova, E.Y, Yu, F, Miller, D.J, Faraldos, J.A, Zhao, Y, Coates, R.M, Allemann, R.K, Cane, D.E, Christianson, D.W.
登録日2008-03-14
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献X-ray Crystallographic Studies of Substrate Binding to Aristolochene Synthase Suggest a Metal Ion Binding Sequence for Catalysis.
J.Biol.Chem., 283, 2008
1VHH
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BU of 1vhh by Molmil
A POTENTIAL CATALYTIC SITE WITHIN THE AMINO-TERMINAL SIGNALLING DOMAIN OF SONIC HEDGEHOG
分子名称: SONIC HEDGEHOG, SULFATE ION, ZINC ION
著者Hall, T.M.T, Porter, J.A, Beachy, P.A, Leahy, D.J.
登録日1995-10-03
公開日1996-01-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A potential catalytic site revealed by the 1.7-A crystal structure of the amino-terminal signalling domain of Sonic hedgehog.
Nature, 378, 1995
3D1B
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BU of 3d1b by Molmil
Tetragonal crystal structure of Tas3 C-terminal alpha motif
分子名称: RNA-induced transcriptional silencing complex protein tas3
著者Li, H, Patel, D.J.
登録日2008-05-05
公開日2009-04-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
5LUF
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BU of 5luf by Molmil
Cryo-EM of bovine respirasome
分子名称: COPPER (II) ION, Cytochrome b, Cytochrome b-c1 complex subunit 1, ...
著者Sousa, J.S, Mills, D.J, Vonck, J, Kuehlbrandt, W.
登録日2016-09-08
公開日2016-11-30
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (9.1 Å)
主引用文献Functional asymmetry and electron flow in the bovine respirasome.
Elife, 5, 2016
1DDV
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BU of 1ddv by Molmil
CRYSTAL STRUCTURE OF THE HOMER EVH1 DOMAIN WITH BOUND MGLUR PEPTIDE
分子名称: GLGF-DOMAIN PROTEIN HOMER, METABOTROPIC GLUTAMATE RECEPTOR MGLUR5
著者Beneken, J, Tu, J.C, Xiao, B, Worley, P.F, Leahy, D.J.
登録日1999-11-11
公開日2000-05-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition.
Neuron, 26, 2000
1UOV
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BU of 1uov by Molmil
Calcium binding domain C2B
分子名称: CALCIUM ION, GLYCEROL, SYNAPTOTAGMIN I
著者Cheng, Y, Sequeira, S.M, Sollner, T.H, Patel, D.J.
登録日2003-09-24
公開日2004-09-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystallographic Identification of Ca2+ and Sr2+ Coordination Sites in Synaptotagmin I C2B Domain
Protein Sci., 13, 2004
6DGR
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Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with CAY10638
分子名称: (5Z)-5-({4-[2-(thiophen-2-yl)ethoxy]phenyl}methylidene)-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma
著者Shang, J, Kojetin, D.J.
登録日2018-05-18
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Quantitative structural assessment of graded receptor agonism.
Proc.Natl.Acad.Sci.USA, 116, 2019
6DGP
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BU of 6dgp by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with TRAP220 Coactivator Peptide
分子名称: Peroxisome proliferator-activated receptor gamma, TRAP220 Coactivator Peptide (Mediator of RNA polymerase II transcription subunit 1)
著者Shang, J, Kojetin, D.J.
登録日2018-05-17
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with TRAP220 Coactivator Peptide
To Be Published
1WOS
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BU of 1wos by Molmil
Crystal Structure of T-protein of the Glycine Cleavage System
分子名称: Aminomethyltransferase
著者Lee, H.H, Kim, D.J, Ahn, H.J, Ha, J.Y, Suh, S.W.
登録日2004-08-24
公開日2004-09-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystal Structure of T-protein of the Glycine Cleavage System: Cofactor binding, insights into H-protein recognition, and molecular basis for understanding nonketotic hyperglycinemia
J.Biol.Chem., 279, 2004
3DAS
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BU of 3das by Molmil
Structure of the PQQ-bound form of Aldose Sugar Dehydrogenase (Adh) from Streptomyces coelicolor
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, PYRROLOQUINOLINE QUINONE, ...
著者Southall, S.M, Doel, J.J, Oubrie, A, Richardson, D.J.
登録日2008-05-30
公開日2009-06-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and Enzymatic Characterization of a Thermostable PQQ-dependent Soluble Aldose Sugar Dehydrogenase
To be Published
6F8E
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PH domain from TgAPH
分子名称: Pleckstrin homology domain
著者Darvill, N, Liu, B, Matthews, S, Soldati-Favre, D, Rouse, S, Benjamin, S, Blake, T, Dubois, D.J, Hammoudi, P.M, Pino, P.
登録日2017-12-13
公開日2019-01-30
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structural Basis of Phosphatidic Acid Sensing by APH in Apicomplexan Parasites.
Structure, 26, 2018
5MY1
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BU of 5my1 by Molmil
E. coli expressome
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Kohler, R, Mooney, R.A, Mills, D.J, Kostrewa, D, Landick, R, Cramer, P.
登録日2017-01-25
公開日2017-04-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Architecture of a transcribing-translating expressome.
Science, 356, 2017
1UPN
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COMPLEX OF ECHOVIRUS TYPE 12 WITH DOMAINS 3 AND 4 OF ITS RECEPTOR DECAY ACCELERATING FACTOR (CD55) BY CRYO ELECTRON MICROSCOPY AT 16 A
分子名称: COMPLEMENT DECAY-ACCELERATING FACTOR, ECHOVIRUS 11 COAT PROTEIN VP1, ECHOVIRUS 11 COAT PROTEIN VP2, ...
著者Bhella, D, Goodfellow, I.G, Roversi, P, Pettigrew, D, Chaudry, Y, Evans, D.J, Lea, S.M.
登録日2003-10-08
公開日2004-01-07
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (16 Å)
主引用文献The Structure of Echovirus Type 12 Bound to a Two-Domain Fragment of its Cellular Attachment Protein Decay-Accelerating Factor (Cd 55)
J.Biol.Chem., 279, 2004
6DH9
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BU of 6dh9 by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with MSDC-0602
分子名称: (5S)-5-({4-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma, nonanoic acid
著者Shang, J, Kojetin, D.J.
登録日2018-05-18
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with MSDC-0602
To Be Published
1ULL
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BU of 1ull by Molmil
RNA APTAMER COMPLEXED WITH HIV-1 REV PEPTIDE, NMR, 7 STRUCTURES
分子名称: REV PEPTIDE, RNA (5'-R (GP*GP*CP*UP*GP*GP*AP*CP*UP*CP*GP*UP*AP*CP*UP*UP*CP*GP* GP*UP*AP*CP*UP*GP*GP*AP*GP*AP*AP*AP*CP*AP*GP*CP*C)-3')
著者Ye, X, Gorin, A, Ellington, A.D, Patel, D.J.
登録日1996-11-05
公開日1997-08-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Deep penetration of an alpha-helix into a widened RNA major groove in the HIV-1 rev peptide-RNA aptamer complex.
Nat.Struct.Biol., 3, 1996
6D8A
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RsAgo Ternary Complex with guide RNA and Target DNA Containing A-A Bulge Within the Seed Segment of the Target Strand
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, DNA (5'-D(P*TP*CP*GP*TP*CP*AP*CP*CP*TP*GP*TP*GP*CP*AP*GP*AP*AP*TP*AP*AP*C)-3'), ...
著者Liu, Y, Esyunina, D, Olovnikov, I, Teplova, M, Patel, D.J.
登録日2018-04-26
公開日2018-07-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Cell Rep, 24, 2018

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