7KYL
| Powassan virus Envelope protein DIII in complex with neutralizing Fab POWV-80 | 分子名称: | CHLORIDE ION, Envelope protein domain III, POWV-80 Fab heavy chain, ... | 著者 | Errico, J.M, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-12-08 | 公開日 | 2021-04-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Broadly neutralizing monoclonal antibodies protect against multiple tick-borne flaviviruses. J.Exp.Med., 218, 2021
|
|
4G91
| CCAAT-binding complex from Aspergillus nidulans | 分子名称: | HAPB protein, HapE, Transcription factor HapC (Eurofung) | 著者 | Huber, E.M, Scharf, D.H, Hortschansky, P, Groll, M, Brakhage, A.A. | 登録日 | 2012-07-23 | 公開日 | 2012-10-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | DNA Minor Groove Sensing and Widening by the CCAAT-Binding Complex. Structure, 20, 2012
|
|
4GF2
| Crystal structure of Plasmodium falciparum Erythrocyte Binding Antigen 140 (PfEBA-140/BAEBL) | 分子名称: | Erythrocyte binding antigen 140, GLYCEROL | 著者 | Lin, D.H, Malpede, B.M, Batchelor, J.D, Tolia, N.H. | 登録日 | 2012-08-02 | 公開日 | 2012-09-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion. J.Biol.Chem., 287, 2012
|
|
4FXB
| Crystal structure of CYP105N1 from Streptomyces coelicolor: a cytochrome P450 oxidase in the coelibactin siderophore biosynthetic pathway | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 | 著者 | Hong, M.K, Lim, Y.R, Kim, J.K, Kim, D.H, Kang, L.W. | 登録日 | 2012-07-03 | 公開日 | 2012-11-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of cytochrome P450 CYP105N1 from Streptomyces coelicolor, an oxidase in the coelibactin siderophore biosynthetic pathway Arch.Biochem.Biophys., 528, 2012
|
|
4GA0
| |
4GA2
| |
7EWI
| Toxin protein from Staphylococcus aureus | 分子名称: | Endoribonuclease MazF, GLYCEROL, PHOSPHATE ION | 著者 | Kim, D.H, Kang, S.M, Lee, S.J, Lee, B.J. | 登録日 | 2021-05-25 | 公開日 | 2022-02-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Role of PemI in the Staphylococcus aureus PemIK toxin-antitoxin complex: PemI controls PemK by acting as a PemK loop mimic. Nucleic Acids Res., 50, 2022
|
|
7EWJ
| Toxin-antitoxin complex from Staphylococcus aureus | 分子名称: | Endoribonuclease MazF, GLYCEROL, PemI inhibitor, ... | 著者 | Kim, D.H, Kang, S.M, Lee, S.J, Lee, B.J. | 登録日 | 2021-05-25 | 公開日 | 2022-02-16 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Role of PemI in the Staphylococcus aureus PemIK toxin-antitoxin complex: PemI controls PemK by acting as a PemK loop mimic. Nucleic Acids Res., 50, 2022
|
|
7FIN
| Cryo-EM structure of the GIPR/GLP-1R/GCGR triagonist peptide 20-bound human GIPR-Gs complex | 分子名称: | CHOLESTEROL, GAMMA-L-GLUTAMIC ACID, Gastric inhibitory polypeptide receptor,human glucose-dependent insulinotropic polypeptide receptor, ... | 著者 | Zhao, F.h, Zhou, Q.T, Cong, Z.T, Hang, K.N, Zou, X.Y, Zhang, C, Chen, Y, Dai, A.T, Liang, A.Y, Ming, Q.Q, Wang, M, Chen, L.N, Xu, P.Y, Chang, R.L, Feng, W.B, Xia, T, Zhang, Y, Wu, B.L, Yang, D.H, Zhao, L.H, Xu, H.E, Wang, M.W. | 登録日 | 2021-07-31 | 公開日 | 2022-02-23 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors. Nat Commun, 13, 2022
|
|
7FIY
| Cryo-EM structure of the tirzepatide-bound human GIPR-Gs complex | 分子名称: | CHOLESTEROL, Gastric inhibitory polypeptide receptor,Gastric inhibitory polypeptide receptor,human glucose-dependent insulinotropic polypeptide receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhao, F.H, Zhou, Q.T, Cong, Z.T, Hang, K.N, Zou, X.Y, Zhang, C, Chen, Y, Dai, A.T, Liang, A.Y, Ming, Q.Q, Wang, M, Chen, L.N, Xu, P.Y, Chang, R.L, Feng, W.B, Xia, T, Zhang, Y, Wu, B.L, Yang, D.H, Zhao, L.H, Xu, H.E, Wang, M.W. | 登録日 | 2021-08-01 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors. Nat Commun, 13, 2022
|
|
7FIM
| Cryo-EM structure of the tirzepatide (LY3298176)-bound human GLP-1R-Gs complex | 分子名称: | Glucagon-like peptide 1 receptor,Glucagon-like peptide 1 receptor,Glucagon-like peptide 1 receptor,Glucagon-like peptide 1 receptor,human glucagon like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhao, F.H, Zhou, Q.T, Cong, Z.T, Hang, K.N, Zou, X.Y, Zhang, C, Chen, Y, Dai, A.T, Liang, A.Y, Ming, Q.Q, Wang, M, Chen, L.N, Xu, P.Y, Chang, R.L, Feng, W.B, Xia, T, Zhang, Y, Wu, B.L, Yang, D.H, Zhao, L.H, Xu, H.E, Wang, M.W. | 登録日 | 2021-07-31 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors. Nat Commun, 13, 2022
|
|
6M19
| Template lasso peptide C24 mutant W14F | 分子名称: | lasso peptide | 著者 | Liu, X.H, Liu, T, Ma, X.J, Yu, J.H, Yang, D.H, Ma, M. | 登録日 | 2020-02-25 | 公開日 | 2021-03-03 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Rational generation of lasso peptides based on biosynthetic gene mutations and site-selective chemical modifications. Chem Sci, 12, 2021
|
|
4GIQ
| Crystal Structure of mouse RANK bound to RANKL | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, SODIUM ION, ... | 著者 | Nelson, C.A, Wang, M.W.-H, Fremont, D.H. | 登録日 | 2012-08-08 | 公開日 | 2012-10-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor. Structure, 20, 2012
|
|
4DD8
| ADAM-8 metalloproteinase domain with bound batimastat | 分子名称: | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, CALCIUM ION, CHLORIDE ION, ... | 著者 | Hall, T, Shieh, H.S, Day, J.E, Caspers, N, Chrencik, J.E, Williams, J.M, Pegg, L.E, Pauley, A.M, Moon, A.F, Krahn, J.M, Fischer, D.H, Kiefer, J.R, Tomasselli, A.G, Zack, M.D. | 登録日 | 2012-01-18 | 公開日 | 2012-06-06 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of human ADAM-8 catalytic domain complexed with batimastat. Acta Crystallogr.,Sect.F, 68, 2012
|
|
6N8I
| |
6N4Z
| Tetragonal thermolysin (with 50% xylose) plunge cooled in liquid nitrogen to 77 K | 分子名称: | CALCIUM ION, Thermolysin, ZINC ION, ... | 著者 | Juers, D.H, Harrison, K, Wu, B. | 登録日 | 2018-11-20 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | A comparison of gas stream cooling and plunge cooling of macromolecular crystals. J.Appl.Crystallogr., 52, 2019
|
|
7FEQ
| Cryo-EM structure of apo BsClpP at pH 6.5 | 分子名称: | ATP-dependent Clp protease proteolytic subunit | 著者 | Kim, L, Lee, B.-G, Kim, M.K, Kwon, D.H, Kim, H, Brotz-Oesterhelt, H, Roh, S.-H, Song, H.K. | 登録日 | 2021-07-21 | 公開日 | 2022-07-06 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis. Embo J., 41, 2022
|
|
6N8F
| |
7JX6
| |
7FES
| Cryo-EM structure of apo BsClpP at pH 4.2 | 分子名称: | ATP-dependent Clp protease proteolytic subunit | 著者 | Kim, L, Lee, B.-G, Kim, M.K, Kwon, D.H, Kim, H, Brotz-Oesterhelt, H, Roh, S.-H, Song, H.K. | 登録日 | 2021-07-21 | 公開日 | 2022-07-06 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis. Embo J., 41, 2022
|
|
7FER
| Cryo-EM structure of BsClpP-ADEP1 complex at pH 4.2 | 分子名称: | ADEP1, ATP-dependent Clp protease proteolytic subunit | 著者 | Kim, L, Lee, B.-G, Kim, M.K, Kwon, D.H, Kim, H, Brotz-Oesterhelt, H, Roh, S.-H, Song, H.K. | 登録日 | 2021-07-21 | 公開日 | 2022-07-06 | 最終更新日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis. Embo J., 41, 2022
|
|
7FEP
| Cryo-EM structure of BsClpP-ADEP1 complex at pH 6.5 | 分子名称: | ADEP1, ATP-dependent Clp protease proteolytic subunit | 著者 | Kim, L, Lee, B.-G, Kim, M.K, Kwon, D.H, Kim, H, Brotz-Oesterhelt, H, Roh, S.-H, Song, H.K. | 登録日 | 2021-07-21 | 公開日 | 2022-07-06 | 最終更新日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into ClpP protease side exit pore-opening by a pH drop coupled with substrate hydrolysis. Embo J., 41, 2022
|
|
6NKK
| Structure of PhqE Reductase/Diels-Alderase from Penicillium fellutanum in complex with NADP+ and premalbrancheamide | 分子名称: | (5aS,12aS,13aS)-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7,6-b]carbazol-14-one, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short chain dehydrogenase | 著者 | Newmister, S.A, Dan, Q, Smith, J.L, Sherman, D.H. | 登録日 | 2019-01-07 | 公開日 | 2019-10-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | 主引用文献 | Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase. Nat.Chem., 11, 2019
|
|
6N4W
| Tetragonal thermolysin (with 50% xylose) cryocooled in a nitrogen gas stream to 100 K | 分子名称: | CALCIUM ION, Thermolysin, ZINC ION, ... | 著者 | Juers, D.H, Harrison, K, Wu, B. | 登録日 | 2018-11-20 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | A comparison of gas stream cooling and plunge cooling of macromolecular crystals. J.Appl.Crystallogr., 52, 2019
|
|
7DOP
| Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1 | 分子名称: | Nonstructural Protein 1, ZINC ION | 著者 | Zhang, K, Law, Y.S, Law, M.C.Y, Tan, Y.B, Wirawan, M, Luo, D.H. | 登録日 | 2020-12-15 | 公開日 | 2021-03-24 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.38 Å) | 主引用文献 | Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1. Cell Host Microbe, 29, 2021
|
|