2AQP
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![BU of 2aqp by Molmil](/molmil-images/mine/2aqp) | CU/ZN superoxide dismutase from neisseria meningitidis E73A mutant | Descriptor: | 1,2-ETHANEDIOL, COPPER (I) ION, Superoxide dismutase [Cu-Zn], ... | Authors: | DiDonato, M, Kassmann, C.J, Bruns, C.K, Cabelli, D.E, Cao, Z, Tabatabai, L.B, Kroll, J.S, Getzoff, E.D. | Deposit date: | 2005-08-18 | Release date: | 2006-10-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | CU/ZN superoxide dismutase from neisseria meningitidis E73A mutant To be Published
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2C66
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![BU of 2c66 by Molmil](/molmil-images/mine/2c66) | MAO inhibition by rasagiline analogues | Descriptor: | 4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN, AMINE OXIDASE (FLAVIN-CONTAINING) B, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Binda, C, Hubalek, F, Li, M, Herzig, Y, Sterling, J, Edmondson, D.E, Mattevi, A. | Deposit date: | 2005-11-07 | Release date: | 2006-01-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Binding of Rasagiline-Related Inhibitors to Human Monoamine Oxidases: A Kinetic and Crystallographic Analysis. J.Med.Chem., 48, 2005
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2AHQ
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2AGI
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![BU of 2agi by Molmil](/molmil-images/mine/2agi) | The leupeptin-trypsin covalent complex at 1.14 A resolution | Descriptor: | CALCIUM ION, SULFATE ION, beta-trypsin, ... | Authors: | Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2005-07-26 | Release date: | 2006-05-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates Proc.Natl.Acad.Sci.USA, 103, 2006
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2AQS
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![BU of 2aqs by Molmil](/molmil-images/mine/2aqs) | CU/ZN superoxide dismutase from neisseria meningitidis K91E, K94E double mutant | Descriptor: | COPPER (I) ION, COPPER (II) ION, Superoxide dismutase [Cu-Zn], ... | Authors: | DiDonato, M, Kassmann, C.J, Bruns, C.K, Cabelli, D.E, Cao, Z, Tabatabai, L.B, Kroll, J.S, Getzoff, E.D. | Deposit date: | 2005-08-18 | Release date: | 2006-10-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | CU/ZN superoxide dismutase from neisseria meningitidis K91E, K94E double mutant To be Published
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2AX1
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![BU of 2ax1 by Molmil](/molmil-images/mine/2ax1) | Hepatitis C Virus NS5b RNA Polymerase in complex with a covalent inhibitor (5ee) | Descriptor: | 5R-(3,4-DICHLOROPHENYLMETHYL)-3-(2-THIOPHENESULFONYLAMINO)-4-OXO-2-THIONOTHIAZOLIDINE, Genome polyprotein, SULFATE ION | Authors: | Powers, J.P, Piper, D.E, Li, Y, Mayorga, V, Anzola, J, Chen, J.M, Jaen, J.C, Lee, G, Liu, J, Peterson, M.G, Tonn, G.R, Ye, Q, Walker, N.P, Wang, Z. | Deposit date: | 2005-09-02 | Release date: | 2006-01-24 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | SAR and Mode of Action of Novel Non-Nucleoside Inhibitors of Hepatitis C NS5b RNA Polymerase. J.Med.Chem., 49, 2006
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2AGE
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![BU of 2age by Molmil](/molmil-images/mine/2age) | Succinyl-AAPR-trypsin acyl-enzyme at 1.15 A resolution | Descriptor: | CALCIUM ION, Cationic trypsin, succinyl-Ala-Ala-Pro-Arg | Authors: | Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2005-07-26 | Release date: | 2006-05-16 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates Proc.Natl.Acad.Sci.USA, 103, 2006
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2E34
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![BU of 2e34 by Molmil](/molmil-images/mine/2e34) | L11 structure with RDC and RG refinement | Descriptor: | 50S ribosomal protein L11 | Authors: | Lee, D, Walsh, J.D, Yu, P, Markus, M.A, Choli-Papadopoulous, T, Schwieters, C.D, Krueger, S, Draper, D.E, Wang, Y.X. | Deposit date: | 2006-11-20 | Release date: | 2007-06-19 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The structure of free L11 and functional dynamics of L11 in free, L11-rRNA(58 nt) binary and L11-rRNA(58 nt)-thiostrepton ternary complexes J.Mol.Biol., 367, 2007
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2E4O
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![BU of 2e4o by Molmil](/molmil-images/mine/2e4o) | X-ray Crystal Structure of Aristolochene Synthase from Aspergillus terreus and the Evolution of Templates for the Cyclization of Farnesyl Diphosphate | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Aristolochene synthase, BETA-MERCAPTOETHANOL, ... | Authors: | Shishova, E.Y, Di Costanzo, L, Cane, D.E, Christianson, D.W. | Deposit date: | 2006-12-15 | Release date: | 2007-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | X-ray crystal structure of aristolochene synthase from Aspergillus terreus and evolution of templates for the cyclization of farnesyl diphosphate. Biochemistry, 46, 2007
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2AQR
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![BU of 2aqr by Molmil](/molmil-images/mine/2aqr) | CU/ZN superoxide dismutase from neisseria meningitidis K91Q mutant | Descriptor: | COPPER (I) ION, COPPER (II) ION, Superoxide dismutase [Cu-Zn], ... | Authors: | DiDonato, M, Kassmann, C.J, Bruns, C.K, Cabelli, D.E, Cao, Z, Tabatabai, L.B, Kroll, J.S, Getzoff, E.D. | Deposit date: | 2005-08-18 | Release date: | 2006-10-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | CU/ZN superoxide dismutase from neisseria meningitidis K91Q mutant To be Published
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2AH4
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![BU of 2ah4 by Molmil](/molmil-images/mine/2ah4) | guanidinobenzoyl-trypsin acyl-enzyme at 1.13 A resolution | Descriptor: | 4-carbamimidamidobenzoic acid, CALCIUM ION, SULFATE ION, ... | Authors: | Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2005-07-26 | Release date: | 2006-05-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.13 Å) | Cite: | Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates Proc.Natl.Acad.Sci.USA, 103, 2006
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2AQQ
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![BU of 2aqq by Molmil](/molmil-images/mine/2aqq) | CU/ZN superoxid dismutate from neisseria meningitidis K91E mutant | Descriptor: | COPPER (I) ION, COPPER (II) ION, SULFATE ION, ... | Authors: | DiDonato, M, Kassmann, C.J, Bruns, C.K, Cabelli, D.E, Cao, Z, Tabatabai, L.B, Kroll, J.S, Getzoff, E.D. | Deposit date: | 2005-08-18 | Release date: | 2006-10-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | CU/ZN superoxid dismutate from neisseria meningitidis K91E mutant To be Published
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2AZX
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![BU of 2azx by Molmil](/molmil-images/mine/2azx) | Charged and uncharged tRNAs adopt distinct conformations when complexed with human tryptophanyl-tRNA synthetase | Descriptor: | 72-MER, GLYCEROL, MAGNESIUM ION, ... | Authors: | Yang, X.L, Otero, F.J, Ewalt, K.L, Liu, J, Swairjo, M.A, Kohrer, C, RajBhandary, U.L, Skene, R.J, McRee, D.E, Schimmel, P. | Deposit date: | 2005-09-12 | Release date: | 2006-08-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Two conformations of a crystalline human tRNA synthetase-tRNA complex: implications for protein synthesis. Embo J., 25, 2006
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2AQN
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![BU of 2aqn by Molmil](/molmil-images/mine/2aqn) | CU/ZN superoxide dismutase from neisseria meningitidis | Descriptor: | COPPER (I) ION, COPPER (II) ION, SULFATE ION, ... | Authors: | DiDonato, M, Kassmann, C.J, Bruns, C.K, Cabelli, D.E, Cao, Z, Tabatabai, L.B, Kroll, J.S, Getzoff, E.D. | Deposit date: | 2005-08-18 | Release date: | 2006-10-31 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | CU/ZN superoxide dismutase from neisseria meningitidis To be Published
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2AGG
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![BU of 2agg by Molmil](/molmil-images/mine/2agg) | succinyl-AAPK-trypsin acyl-enzyme at 1.28 A resolution | Descriptor: | CALCIUM ION, Cationic trypsin, SULFATE ION, ... | Authors: | Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2005-07-26 | Release date: | 2006-05-16 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates Proc.Natl.Acad.Sci.USA, 103, 2006
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2AQT
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![BU of 2aqt by Molmil](/molmil-images/mine/2aqt) | CU/ZN superoxide dismutase from neisseria meningitidis K91Q, K94Q double mutant | Descriptor: | COPPER (I) ION, COPPER (II) ION, SULFATE ION, ... | Authors: | DiDonato, M, Kassmann, C.J, Bruns, C.K, Cabelli, D.E, Cao, Z, Tabatabai, L.B, Kroll, J.S, Getzoff, E.D. | Deposit date: | 2005-08-18 | Release date: | 2006-10-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | CU/ZN superoxide dismutase from neisseria meningitidis K91Q, K94Q double mutant To be Published
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2AKW
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![BU of 2akw by Molmil](/molmil-images/mine/2akw) | Crystal Structure of T.Thermophilus Phenylalanyl-tRNA synthetase complexed with p-Cl-Phenylalanine | Descriptor: | 4-CHLORO-L-PHENYLALANINE, MANGANESE (II) ION, Phenylalanyl-tRNA synthetase alpha chain, ... | Authors: | Kotik-Kogan, O.M, Moor, N.A, Tworowski, D.E, Safro, M.G. | Deposit date: | 2005-08-04 | Release date: | 2005-12-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for Discrimination of L-Phenylalanine from L-Tyrosine by Phenylalanyl-tRNA Synthetase Structure, 13, 2005
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2AX0
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![BU of 2ax0 by Molmil](/molmil-images/mine/2ax0) | Hepatitis C Virus NS5b RNA Polymerase in complex with a covalent inhibitor (5x) | Descriptor: | 5R-(2E-METHYL-3-PHENYL-ALLYL)-3-(BENZENESULFONYLAMINO)-4-OXO-2-THIONOTHIAZOLIDINE, Genome polyprotein, SULFATE ION | Authors: | Powers, J.P, Piper, D.E, Li, Y, Mayorga, V, Anzola, J, Chen, J.M, Jaen, J.C, Lee, G, Liu, J, Peterson, M.G, Tonn, G.R, Ye, Q, Walker, N.P, Wang, Z. | Deposit date: | 2005-09-02 | Release date: | 2006-01-24 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | SAR and Mode of Action of Novel Non-Nucleoside Inhibitors of Hepatitis C NS5b RNA Polymerase. J.Med.Chem., 49, 2006
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2AWZ
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![BU of 2awz by Molmil](/molmil-images/mine/2awz) | Hepatitis C Virus NS5b RNA Polymerase in complex with a covalent inhibitor (5h) | Descriptor: | 5R-(4-BROMOPHENYLMETHYL)-3-(BENZENESULFONYLAMINO)-4-OXO-2-THIONOTHIAZOLIDINE, Genome polyprotein, SULFATE ION | Authors: | Powers, J.P, Piper, D.E, Li, Y, Mayorga, V, Anzola, J, Chen, J.M, Jaen, J.C, Lee, G, Liu, J, Peterson, M.G, Tonn, G.R, Ye, Q, Walker, N.P, Wang, Z. | Deposit date: | 2005-09-02 | Release date: | 2006-01-24 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | SAR and Mode of Action of Novel Non-Nucleoside Inhibitors of Hepatitis C NS5b RNA Polymerase. J.Med.Chem., 49, 2006
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2ALY
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![BU of 2aly by Molmil](/molmil-images/mine/2aly) | Crystal Structure of T.Thermophilus Phenylalanyl-tRNA synthetase complexed with 5'-O-[N-(L-tyrosyl)sulphamoyl]adenosine | Descriptor: | 5'-O-[N-(L-TYROSYL)SULFAMOYL]ADENOSINE, MANGANESE (II) ION, Phenylalanyl-tRNA synthetase alpha chain, ... | Authors: | Kotik-Kogan, O.M, Moor, N.A, Tworowski, D.E, Safro, M.G. | Deposit date: | 2005-08-04 | Release date: | 2005-12-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Basis for Discrimination of L-Phenylalanine from L-Tyrosine by Phenylalanyl-tRNA Synthetase Structure, 13, 2005
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2ERC
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![BU of 2erc by Molmil](/molmil-images/mine/2erc) | CRYSTAL STRUCTURE OF ERMC' A RRNA-METHYL TRANSFERASE | Descriptor: | RRNA METHYL TRANSFERASE | Authors: | Bussiere, D.E, Muchmore, S.W, Dealwis, C.G, Schluckebier, G, Abad-Zapatero, C. | Deposit date: | 1998-03-13 | Release date: | 1999-03-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | Crystal structure of ErmC', an rRNA methyltransferase which mediates antibiotic resistance in bacteria. Biochemistry, 37, 1998
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2CUA
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![BU of 2cua by Molmil](/molmil-images/mine/2cua) | THE CUA DOMAIN OF CYTOCHROME BA3 FROM THERMUS THERMOPHILUS | Descriptor: | DINUCLEAR COPPER ION, PROTEIN (CUA), ZINC ION | Authors: | Williams, P.A, Blackburn, N.J, Sanders, D, Bellamy, H, Stura, E.A, Fee, J.A, Mcree, D.E. | Deposit date: | 1999-02-18 | Release date: | 1999-05-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The CuA domain of Thermus thermophilus ba3-type cytochrome c oxidase at 1.6 A resolution. Nat.Struct.Biol., 6, 1999
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2F17
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![BU of 2f17 by Molmil](/molmil-images/mine/2f17) | Mouse Thiamin Pyrophosphokinase in a Ternary Complex with Pyrithiamin Pyrophosphate and AMP at 2.5 angstrom | Descriptor: | 1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-2-METHYLPYRIDINIUM, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE MONOPHOSPHATE, ... | Authors: | Liu, J.Y, Timm, D.E, Hurley, T.D. | Deposit date: | 2005-11-14 | Release date: | 2005-11-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Pyrithiamine as a substrate for thiamine pyrophosphokinase J.Biol.Chem., 281, 2006
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2E35
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![BU of 2e35 by Molmil](/molmil-images/mine/2e35) | the minimized average structure of L11 with rg refinement | Descriptor: | 50S ribosomal protein L11 | Authors: | Lee, D, Walsh, J.D, Yu, P, Markus, M.A, Choli-Papadopoulous, T, Schwieters, C.D, Krueger, S, Draper, D.E, Wang, Y.X. | Deposit date: | 2006-11-20 | Release date: | 2007-06-19 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The structure of free L11 and functional dynamics of L11 in free, L11-rRNA(58 nt) binary and L11-rRNA(58 nt)-thiostrepton ternary complexes J.Mol.Biol., 367, 2007
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2E36
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![BU of 2e36 by Molmil](/molmil-images/mine/2e36) | L11 with SANS refinement | Descriptor: | 50S ribosomal protein L11 | Authors: | Lee, D, Walsh, J.D, Yu, P, Markus, M.A, Choli-Papadopoulous, T, Schwieters, C.D, Krueger, S, Draper, D.E, Wang, Y.X. | Deposit date: | 2006-11-20 | Release date: | 2007-06-19 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The structure of free L11 and functional dynamics of L11 in free, L11-rRNA(58 nt) binary and L11-rRNA(58 nt)-thiostrepton ternary complexes J.Mol.Biol., 367, 2007
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