6V0I
 
 | | Lipophilic Envelope-spanning Tunnel B (LetB), Model 7 | | 分子名称: | Intermembrane transport protein YebT | | 著者 | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | | 登録日 | 2019-11-18 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | | 主引用文献 | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
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5UVN
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6V0P
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6V0C
 | | Lipophilic Envelope-spanning Tunnel B (LetB), Model 1 | | 分子名称: | Intermembrane transport protein YebT | | 著者 | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | | 登録日 | 2019-11-18 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
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5X80
 | | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MARR FAMILY PROTEIN RV2887 COMPLEX WITH SALICYLIC ACID | | 分子名称: | 2-HYDROXYBENZOIC ACID, SULFATE ION, Uncharacterized HTH-type transcriptional regulator Rv2887 | | 著者 | Gao, Y.R, Li, D.F, Wang, D.C, Bi, L.J. | | 登録日 | 2017-02-28 | | 公開日 | 2017-08-09 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural analysis of the regulatory mechanism of MarR protein Rv2887 in M. tuberculosis
Sci Rep, 7, 2017
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6V0E
 | | Lipophilic Envelope-spanning Tunnel B (LetB), Model 3 | | 分子名称: | Intermembrane transport protein YebT | | 著者 | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | | 登録日 | 2019-11-18 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
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6VCI
 | | Lipophilic envelope-spanning tunnel protein (LetB), domains MCE2-MCE3 | | 分子名称: | Lipophilic envelope-spanning tunnel protein LetB | | 著者 | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | | 登録日 | 2019-12-21 | | 公開日 | 2020-05-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
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6V0D
 | | Lipophilic Envelope-spanning Tunnel B (LetB), Model 2 | | 分子名称: | Intermembrane transport protein YebT | | 著者 | Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G. | | 登録日 | 2019-11-18 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
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6SXA
 | | XPF-ERCC1 Cryo-EM Structure, Apo-form | | 分子名称: | DNA excision repair protein ERCC-1, DNA repair endonuclease XPF | | 著者 | Jones, M.L, Briggs, D.C, McDonald, N.Q. | | 登録日 | 2019-09-25 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structures of the XPF-ERCC1 endonuclease reveal how DNA-junction engagement disrupts an auto-inhibited conformation.
Nat Commun, 11, 2020
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5U5I
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6VPG
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6VPM
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6VPI
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5X7Z
 | | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS MARR FAMILY PROTEIN RV2887 COMPLEX WITH P-AMINOSALICYLIC ACID | | 分子名称: | 2-HYDROXY-4-AMINOBENZOIC ACID, Uncharacterized HTH-type transcriptional regulator Rv2887 | | 著者 | Gao, Y.R, Li, D.F, Wang, D.C, Bi, L.J. | | 登録日 | 2017-02-28 | | 公開日 | 2017-08-09 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural analysis of the regulatory mechanism of MarR protein Rv2887 in M. tuberculosis
Sci Rep, 7, 2017
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1WSX
 | | Solution structure of MCL-1 | | 分子名称: | myeloid cell leukemia sequence 1 | | 著者 | Day, C.L, Chen, L, Richardson, S.J, Harrison, P.J, Huang, D.C, Hinds, M.G. | | 登録日 | 2004-11-12 | | 公開日 | 2004-11-23 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of Prosurvival Mcl-1 and Characterization of Its Binding by Proapoptotic BH3-only Ligands
J.Biol.Chem., 280, 2005
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4F6N
 | | Crystal structure of Kaiso zinc finger DNA binding protein in complex with methylated CpG site DNA | | 分子名称: | DNA (5'-D(*CP*GP*TP*AP*TP*AP*GP*AP*(5CM)P*GP*(5CM)P*GP*GP*TP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*AP*CP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*AP*TP*AP*CP*G)-3'), GLYCEROL, ... | | 著者 | Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E. | | 登録日 | 2012-05-15 | | 公開日 | 2012-09-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4F6M
 | | Crystal structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA | | 分子名称: | DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), Transcriptional regulator Kaiso, ... | | 著者 | Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E. | | 登録日 | 2012-05-15 | | 公開日 | 2012-09-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012
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1WOD
 | | CRYSTAL STRUCTURE OF MODA, A MOLYBDATE PROTEIN, COMPLEXED WITH TUNGSTATE | | 分子名称: | MODA, TUNGSTATE(VI)ION | | 著者 | Hu, Y, Rech, S, Gunsalus, R.P, Rees, D.C. | | 登録日 | 1997-06-17 | | 公開日 | 1997-12-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of the molybdate binding protein ModA.
Nat.Struct.Biol., 4, 1997
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4GMS
 | | Crystal structure of heterosubtypic Fab S139/1 in complex with influenza A H3 hemagglutinin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab S139/1 heavy chain, ... | | 著者 | Lee, P.S, Ekiert, D.C, Wilson, I.A. | | 登録日 | 2012-08-16 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4G04
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4GEE
 | | Pyrrolopyrimidine inhibitors of DNA gyrase B and topoisomerase IV, part I: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity. | | 分子名称: | (1R,5S,6s)-3-[5-chloro-6-ethyl-2-(pyrimidin-5-yloxy)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-3-azabicyclo[3.1.0]hexan-6-amine, DNA gyrase subunit B, GLYCEROL | | 著者 | Bensen, D.C, Chen, Z, Tari, L.W. | | 登録日 | 2012-08-01 | | 公開日 | 2013-02-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity.
Bioorg.Med.Chem.Lett., 23, 2013
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4GBA
 | | DCNL complex with N-terminally acetylated NEDD8 E2 peptide | | 分子名称: | DCN1-like protein 3, NEDD8-conjugating enzyme UBE2F | | 著者 | Monda, J.K, Scott, D.C, Miller, D.J, Harper, J.W, Bennett, E.J, Schulman, B.A. | | 登録日 | 2012-07-26 | | 公開日 | 2012-11-28 | | 最終更新日 | 2013-01-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Conservation of Distinctive N-terminal Acetylation-Dependent Interactions across a Family of Mammalian NEDD8 Ligation Enzymes.
Structure, 21, 2013
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4GFN
 | | Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic | | 分子名称: | (1R,5S,6s)-3-[5-chloro-6-ethyl-2-(pyrimidin-5-ylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-3-azabicyclo[3.1.0]hexan-6-amine, DNA gyrase subunit B, GLYCEROL | | 著者 | Bensen, D.C, Trzoss, M, Tari, L.W. | | 登録日 | 2012-08-03 | | 公開日 | 2013-02-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity.
Bioorg.Med.Chem.Lett., 23, 2013
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4G8B
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4G9E
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