6SXA
XPF-ERCC1 Cryo-EM Structure, Apo-form
Summary for 6SXA
Entry DOI | 10.2210/pdb6sxa/pdb |
EMDB information | 10337 |
Descriptor | DNA repair endonuclease XPF, DNA excision repair protein ERCC-1 (2 entities in total) |
Functional Keywords | dna repair enzyme. nucleotide excision repair, dna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 137234.46 |
Authors | Jones, M.L.,Briggs, D.C.,McDonald, N.Q. (deposition date: 2019-09-25, release date: 2020-03-11, Last modification date: 2024-05-22) |
Primary citation | Jones, M.,Beuron, F.,Borg, A.,Nans, A.,Earl, C.P.,Briggs, D.C.,Snijders, A.P.,Bowles, M.,Morris, E.P.,Linch, M.,McDonald, N.Q. Cryo-EM structures of the XPF-ERCC1 endonuclease reveal how DNA-junction engagement disrupts an auto-inhibited conformation. Nat Commun, 11:1120-1120, 2020 Cited by PubMed: 32111838DOI: 10.1038/s41467-020-14856-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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