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PDB: 22322 results

4CAC
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BU of 4cac by Molmil
REFINED STRUCTURE OF HUMAN CARBONIC ANHYDRASE II AT 2.0 ANGSTROMS RESOLUTION
Descriptor: CARBONIC ANHYDRASE FORM C, ZINC ION
Authors:Lindahl, M, Habash, D, Harrop, S, Helliwell, D.R, Liljas, A.
Deposit date:1991-09-05
Release date:1994-01-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Refined structure of human carbonic anhydrase II at 2.0 A resolution.
Proteins, 4, 1988
4JOI
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BU of 4joi by Molmil
Crystal structure of the human telomeric Stn1-Ten1 complex
Descriptor: CST complex subunit STN1, CST complex subunit TEN1
Authors:Bryan, C, Rice, C, Harkisheimer, M, Schultz, D, Skordalakes, E.
Deposit date:2013-03-18
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the human telomeric stn1-ten1 capping complex.
Plos One, 8, 2013
4JQF
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BU of 4jqf by Molmil
Structure of the C-terminal domain of human telomeric Stn1
Descriptor: CST complex subunit STN1
Authors:Bryan, C.F, Rice, C.T, Harkisheimer, M, Schultz, D, Skordalakes, E.
Deposit date:2013-03-20
Release date:2013-06-05
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the human telomeric stn1-ten1 capping complex.
Plos One, 8, 2013
4BKN
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BU of 4bkn by Molmil
Human Dihydropyrimidinase-related protein 3 (DPYSL3)
Descriptor: DIHYDROPYRIMIDINASE-RELATED PROTEIN 3
Authors:Mathea, S, Elkins, J.M, Alegre-Abarrategui, J, Shrestha, L, Burgess-Brown, N, Puranik, S, Coutandin, D, Bradley, A, Vollmar, M, von Delft, F, Bountra, C, Arrowsmith, C, Edwards, A, Knapp, S.
Deposit date:2013-04-26
Release date:2013-05-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of Dpysl3
To be Published
4JKO
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Crystal structure of a catalytic mutant of Axe2 (Axe2_S15A), an acetylxylan esterase from Geobacillus stearothermophilus
Descriptor: Acetyl xylan esterase, GLYCEROL, PHOSPHATE ION
Authors:Azulay, D, Lansky, S, Alalouf, O, Solomon, V, Alhassid, A, Belrahli, H, Govada, L, Chayan, N.E, Shoham, Y, Shoham, G.
Deposit date:2013-03-11
Release date:2014-02-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A unique octameric structure of Axe2, an intracellular acetyl-xylooligosaccharide esterase from Geobacillus stearothermophilus.
Acta Crystallogr.,Sect.D, 70, 2014
4F4J
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BU of 4f4j by Molmil
Conversion of the enzyme guanylate kinase into a mitotic spindle orienting protein by a single mutation that inhibits gmp- induced closing
Descriptor: Guanylate kinase, SULFATE ION
Authors:Johnston, C.A, Whitney, D, Volkman, B.F, Prehoda, K.E.
Deposit date:2012-05-10
Release date:2012-06-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Conversion of the enzyme guanylate kinase into a mitotic-spindle orienting protein by a single mutation that inhibits GMP-induced closing.
Proc.Natl.Acad.Sci.USA, 108, 2011
4EYW
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BU of 4eyw by Molmil
Crystal structure of rat carnitine palmitoyltransferase 2 in complex with 1-[(R)-2-(3,4-Dihydro-1H-isoquinoline-2-carbonyl)-piperidin-1-yl]-2-phenoxy-ethanone
Descriptor: 1-[(2R)-2-(3,4-dihydroisoquinolin-2(1H)-ylcarbonyl)piperidin-1-yl]-2-phenoxyethanone, Carnitine O-palmitoyltransferase 2, mitochondrial, ...
Authors:Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Rufer, A, Joseph, C.
Deposit date:2012-05-02
Release date:2013-04-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.885 Å)
Cite:Isothermal titration calorimetry with micelles: Thermodynamics of inhibitor binding to carnitine palmitoyltransferase 2 membrane protein.
FEBS Open Bio, 3, 2013
3PNW
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BU of 3pnw by Molmil
Crystal Structure of the tudor domain of human TDRD3 in complex with an anti-TDRD3 FAB
Descriptor: FAB heavy chain, FAB light chain, Tudor domain-containing protein 3, ...
Authors:Loppnau, P, Tempel, W, Wernimont, A.K, Lam, R, Ravichandran, M, Adams-Cioaba, M.A, Persson, H, Sidhu, S.S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Cossar, D, Structural Genomics Consortium (SGC)
Deposit date:2010-11-19
Release date:2010-12-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:CDR-H3 Diversity Is Not Required for Antigen Recognition by Synthetic Antibodies.
J.Mol.Biol., 425, 2013
3QKI
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BU of 3qki by Molmil
Crystal structure of Glucose-6-Phosphate Isomerase (PF14_0341) from Plasmodium falciparum 3D7
Descriptor: Glucose-6-phosphate isomerase
Authors:Gileadi, T, Wernimont, A.K, Hutchinson, A, Weadge, J, Cossar, D, Lew, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Hills, T, Pizarro, J.C, Structural Genomics Consortium (SGC)
Deposit date:2011-02-01
Release date:2011-02-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of Glucose-6-Phosphate Isomerase (PF14_0341) from Plasmodium falciparum 3D7
TO BE PUBLISHED
3RZ2
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BU of 3rz2 by Molmil
Crystal of Prl-1 complexed with peptide
Descriptor: Prl-1 (PTP4A1), Protein tyrosine phosphatase type IVA 1
Authors:Zhang, Z.-Y, Liu, D, Bai, Y.
Deposit date:2011-05-11
Release date:2011-10-26
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein.
J.Biol.Chem., 286, 2011
3PO6
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BU of 3po6 by Molmil
Crystal structure of human carbonic anhydrase II with 6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide
Descriptor: (1R)-6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide, (1S)-6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide, ACETATE ION, ...
Authors:Mader, P, Brynda, J, Gitto, R, Agnello, S, Ferro, S, De Luca, L, Vullo, D, Supuran, C.T, Chimirri, A.
Deposit date:2010-11-22
Release date:2011-04-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structural basis for the interaction between carbonic anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides.
J.Med.Chem., 54, 2011
3PYM
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BU of 3pym by Molmil
Structure of GAPDH 3 from S.cerevisiae at 2.0 A resolution
Descriptor: Glyceraldehyde-3-phosphate dehydrogenase 3, MESO-ERYTHRITOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Garcia-Saez, I, Kozielski, F, Job, D, Boscheron, C.
Deposit date:2010-12-13
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:

7JUK
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BU of 7juk by Molmil
Crystal structure of PTEN with a tetra-phosphorylated tail (4p-crPTEN-13sp-T2, SDTTDSDPENEG)
Descriptor: PHOSPHATE ION, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Authors:Dempsey, D, Phan, K, Cole, P, Gabelli, S.B.
Deposit date:2020-08-19
Release date:2021-10-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The structural basis of PTEN regulation by multi-site phosphorylation.
Nat.Struct.Mol.Biol., 28, 2021
7KH2
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BU of 7kh2 by Molmil
Structure of N-citrylornithine decarboxylase bound with PLP
Descriptor: GLYCEROL, N-citrylornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Deng, X, Tomchick, D, Phillips, M, Michael, A.
Deposit date:2020-10-19
Release date:2020-12-16
Last modified:2021-07-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Alternative pathways utilize or circumvent putrescine for biosynthesis of putrescine-containing rhizoferrin.
J.Biol.Chem., 296, 2020
7L4U
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BU of 7l4u by Molmil
Crystal structure of human monoacylglycerol lipase in complex with compound 1h
Descriptor: (5S)-5-(3-{4-[(2-chloro-4-fluorophenoxy)methyl]piperidin-1-yl}-3-oxopropyl)pyrrolidin-2-one, CHLORIDE ION, Monoglyceride lipase
Authors:Qin, L, Lane, W, Skene, R.J, Dougan, D.
Deposit date:2020-12-21
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2 H -benzo[ b ][1,4]oxazin-6-yl Moiety.
J.Med.Chem., 64, 2021
7KC4
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BU of 7kc4 by Molmil
Human WLS in complex with WNT8A
Descriptor: 1-CIS-9-OCTADECANOYL-2-CIS-9-HEXADECANOYL PHOSPHATIDYL GLYCEROL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
Authors:Nygaard, R, Jia, Y, Kim, J, Ross, D, Parisi, G, Clarke, O.B, Virshup, D.M, Mancia, F.
Deposit date:2020-10-05
Release date:2021-01-06
Last modified:2021-01-20
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structural Basis of WLS/Evi-Mediated Wnt Transport and Secretion.
Cell, 184, 2021
3RPL
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BU of 3rpl by Molmil
D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase of Synechocystis sp. PCC 6803 in complex with FRUCTOSE-1,6-BISPHOSPHATE
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
Authors:Hu, X, Hui, D, Lingling, F, Jian, W.
Deposit date:2011-04-26
Release date:2012-05-02
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:New insights into the structural and interactional basis for a promising route towards fructose-1,6-/sedoheptulose-1,7-bisphosphatases controlling
To be Published
3T9I
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BU of 3t9i by Molmil
Pim1 complexed with a novel 3,6-disubstituted indole at 2.6 Ang Resolution
Descriptor: 2-methoxy-4-(3-phenyl-2H-pyrazolo[3,4-b]pyridin-6-yl)phenol, Proto-oncogene serine/threonine-protein kinase pim-1
Authors:Bellamacina, C, Shu, W, Le, V, Nishiguchi, G, Bussiere, D.
Deposit date:2011-08-02
Release date:2011-10-12
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery of novel 3,5-disubstituted indole derivatives as potent inhibitors of Pim-1, Pim-2, and Pim-3 protein kinases.
Bioorg.Med.Chem.Lett., 21, 2011
3SWM
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BU of 3swm by Molmil
The NAC domain of ANAC019 in complex with DNA, gold derivative
Descriptor: GOLD ION, NAC domain-containing protein 19, oligonucleotide forward, ...
Authors:Welner, D, Lo Leggio, L.
Deposit date:2011-07-14
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.25 Å)
Cite:DNA binding by the plant-specific NAC transcription factors in crystal and solution: a firm link to WRKY and GCM transcription factors.
Biochem.J., 444, 2012
7LHG
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BU of 7lhg by Molmil
Cryo-EM structure of E. coli P pilus tip assembly intermediate PapC-PapD-PapK-PapG in the first conformation
Descriptor: Chaperone protein PapD, Fimbrial adapter PapK, P fimbria tip G-adhesin PapG-II, ...
Authors:Du, M, Yuan, Z, Werneburg, G, Henderson, N, Chauhan, H, Kovach, A, Zhao, G, Johl, J, Li, H, Thanassi, D.
Deposit date:2021-01-23
Release date:2021-08-11
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Processive dynamics of the usher assembly platform during uropathogenic Escherichia coli P pilus biogenesis.
Nat Commun, 12, 2021
7LHH
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BU of 7lhh by Molmil
Cryo-EM structure of E. coli P pilus tip assembly intermediate PapC-PapD-PapK-PapG in the second conformation
Descriptor: Chaperone protein PapD, Fimbrial adapter PapK, P fimbria tip G-adhesin PapG-II, ...
Authors:Du, M, Yuan, Z, Werneburg, G, Henderson, N, Chauhan, H, Kovach, A, Zhao, G, Johl, J, Li, H, Thanassi, D.
Deposit date:2021-01-23
Release date:2021-08-11
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Processive dynamics of the usher assembly platform during uropathogenic Escherichia coli P pilus biogenesis.
Nat Commun, 12, 2021
3PR3
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BU of 3pr3 by Molmil
Crystal structure of Plasmodium falciparum glucose-6-phosphate isomerase (PF14_0341) in complex with fructose-6-phosphate
Descriptor: 6-O-phosphono-beta-D-fructofuranose, Glucose-6-phosphate isomerase, PHOSPHATE ION
Authors:Gileadi, T, Wernimont, A.K, Hutchinson, A, Weadge, J, Cossar, D, Lew, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Hills, T, Pizarro, J.C, Structural Genomics Consortium (SGC)
Deposit date:2010-11-29
Release date:2011-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of Plasmodium falciparum glucose-6-phosphate isomerase (PF14_0341) in complex with fructose-6-phosphate
To be Published
3Q4L
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BU of 3q4l by Molmil
Structure of a small peptide ligand bound to E.coli DNA sliding clamp
Descriptor: DNA polymerase III subunit beta, SODIUM ION, peptide ligand
Authors:Wolff, P, Olieric, V, Briand, J.P, Chaloin, O, Dejaegere, A, Dumas, P, Ennifar, E, Guichard, G, Wagner, J, Burnouf, D.
Deposit date:2010-12-23
Release date:2011-12-28
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure-based design of short peptide ligands binding onto the E. coli processivity ring.
J.Med.Chem., 54, 2011
3T29
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BU of 3t29 by Molmil
TMAO-grown trigonal trypsin (bovine)
Descriptor: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ...
Authors:Cahn, J, Venkat, M, Marshall, H, Juers, D.
Deposit date:2011-07-22
Release date:2011-12-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
7L0K
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Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM784 (3-(1-(3-methyl-4-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1H-pyrrole-2-carboxamido)ethyl)-1H-pyrazole-5-carboxamide)
Descriptor: 3-{(1R)-1-[(3-methyl-4-{[6-(trifluoromethyl)pyridin-3-yl]methyl}-1H-pyrrole-2-carbonyl)amino]ethyl}-1H-pyrazole-5-carboxamide, Dihydroorotate dehydrogenase (quinone), mitochondrial, ...
Authors:Deng, X, Phillips, M, Tomchick, D.
Deposit date:2020-12-11
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series.
J.Med.Chem., 64, 2021

224004

數據於2024-08-21公開中

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