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4EYW

Crystal structure of rat carnitine palmitoyltransferase 2 in complex with 1-[(R)-2-(3,4-Dihydro-1H-isoquinoline-2-carbonyl)-piperidin-1-yl]-2-phenoxy-ethanone

Summary for 4EYW
Entry DOI10.2210/pdb4eyw/pdb
DescriptorCarnitine O-palmitoyltransferase 2, mitochondrial, 1-[(2R)-2-(3,4-dihydroisoquinolin-2(1H)-ylcarbonyl)piperidin-1-yl]-2-phenoxyethanone, HEXAETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywordsacyltransferase, mitochondrial protein, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceRattus norvegicus (brown rat,rat,rats)
Cellular locationMitochondrion inner membrane ; Peripheral membrane protein ; Matrix side : P18886
Total number of polymer chains2
Total formula weight144387.37
Authors
Rudolph, M.G.,Benz, J.,Burger, D.,Thoma, R.,Rufer, A.,Joseph, C. (deposition date: 2012-05-02, release date: 2013-04-24, Last modification date: 2024-02-28)
Primary citationPerspicace, S.,Rufer, A.C.,Thoma, R.,Mueller, F.,Hennig, M.,Ceccarelli, S.,Schulz-Gasch, T.,Seelig, J.
Isothermal titration calorimetry with micelles: Thermodynamics of inhibitor binding to carnitine palmitoyltransferase 2 membrane protein.
FEBS Open Bio, 3:204-211, 2013
Cited by
PubMed: 23772395
DOI: 10.1016/j.fob.2013.04.003
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.885 Å)
Structure validation

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