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4EYW

Crystal structure of rat carnitine palmitoyltransferase 2 in complex with 1-[(R)-2-(3,4-Dihydro-1H-isoquinoline-2-carbonyl)-piperidin-1-yl]-2-phenoxy-ethanone

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Carnitine O-palmitoyltransferase 2, mitochondrialpolymer63471532.92UniProt (P18886)
Pfam (PF00755)
Rattus norvegicus (brown rat rat rats)Carnitine palmitoyltransferase II, CPT II
2C, E
(A, B)
1-[(2R)-2-(3,4-dihydroisoquinolin-2(1H)-ylcarbonyl)piperidin-1-yl]-2-phenoxyethanonenon-polymer378.52Chemie (L0R)
3D, F
(A, B)
HEXAETHYLENE GLYCOLnon-polymer282.32Chemie (P6G)
4G, H
(A, B)
waterwater18.01189Chemie (HOH)
Sequence modifications
A, B: 27 - 658 (UniProt: P18886)
PDBExternal DatabaseDetails
His 25-expression tag
Met 26-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight143065.8
Non-Polymers*Number of molecules4
Total formula weight1321.6
All*Total formula weight144387.4
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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