3DO7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3do7 by Molmil](/molmil-images/mine/3do7) | X-ray structure of a NF-kB p52/RelB/DNA complex | 分子名称: | 5'-D(*DCP*DGP*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DCP*DC)-3', Avian reticuloendotheliosis viral (V-rel) oncogene related B, Nuclear factor NF-kappa-B p100 subunit | 著者 | Fusco, A, Huang, D.B, Miller, D, Vu, D, Ghosh, G. | 登録日 | 2008-07-03 | 公開日 | 2009-07-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | NF-kapppaB p52:RelB heterodimer uses different binding modes to recognize different kappaB DNA TO BE PUBLISHED
|
|
3EAC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3eac by Molmil](/molmil-images/mine/3eac) | |
2CFO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cfo by Molmil](/molmil-images/mine/2cfo) | Non-Discriminating Glutamyl-tRNA Synthetase from Thermosynechococcus elongatus in Complex with Glu | 分子名称: | GLUTAMIC ACID, GLUTAMYL-TRNA SYNTHETASE | 著者 | Schulze, J.O, Nickel, D, Schubert, W.-D, Jahn, D, Heinz, D.W. | 登録日 | 2006-02-22 | 公開日 | 2006-08-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal Structure of a Non-Discriminating Glutamyl- tRNA Synthetase. J.Mol.Biol., 361, 2006
|
|
2C8P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2c8p by Molmil](/molmil-images/mine/2c8p) | lysozyme (60sec) and UV laser excited fluorescence | 分子名称: | LYSOZYME C | 著者 | Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D. | 登録日 | 2005-12-06 | 公開日 | 2006-03-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops. Acta Crystallogr.,Sect.D, 62, 2006
|
|
8GEL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gel by Molmil](/molmil-images/mine/8gel) | Cryo-EM structure of synthetic tetrameric building block sC4 | 分子名称: | sC4 | 著者 | Redler, R.L, Huddy, T.F, Hsia, Y, Baker, D, Ekiert, D, Bhabha, G. | 登録日 | 2023-03-07 | 公開日 | 2024-03-13 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Blueprinting extendable nanomaterials with standardized protein blocks. Nature, 627, 2024
|
|
8VEI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vei by Molmil](/molmil-images/mine/8vei) | |
8VEJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vej by Molmil](/molmil-images/mine/8vej) | De novo designed cholic acid binder: CHD_buttress | 分子名称: | CHD_buttress, CHOLIC ACID | 著者 | Bera, A.K, Tran, L, Kang, A, Baker, D. | 登録日 | 2023-12-19 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (3.59 Å) | 主引用文献 | Binding and sensing diverse small molecules using shape-complementary pseudocycles. Science, 385, 2024
|
|
3EAZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3eaz by Molmil](/molmil-images/mine/3eaz) | |
7B83
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7b83 by Molmil](/molmil-images/mine/7b83) | Structure of SARS-CoV-2 Main Protease bound to pyrithione zinc | 分子名称: | 3C-like proteinase, 9-oxa-7-thia-1-azonia-8$l^{2}-zincabicyclo[4.3.0]nona-1,3,5-triene, CHLORIDE ION, ... | 著者 | Guenther, S, Reinke, P, Oberthuer, D, Yefanov, O, Gelisio, L, Ginn, H, Lieske, J, Domaracky, M, Brehm, W, Rahmani Mashour, A, White, T.A, Knoska, J, Pena Esperanza, G, Koua, F, Tolstikova, A, Groessler, M, Fischer, P, Hennicke, V, Fleckenstein, H, Trost, F, Galchenkova, M, Gevorkov, Y, Li, C, Awel, S, Paulraj, L.X, Ullah, N, Falke, S, Alves Franca, B, Schwinzer, M, Brognaro, H, Werner, N, Perbandt, M, Tidow, H, Seychell, B, Beck, T, Meier, S, Doyle, J.J, Giseler, H, Melo, D, Dunkel, I, Lane, T.J, Peck, A, Saouane, S, Hakanpaeae, J, Meyer, J, Noei, H, Gribbon, P, Ellinger, B, Kuzikov, M, Wolf, M, Zhang, L, Ehrt, C, Pletzer-Zelgert, J, Wollenhaupt, J, Feiler, C, Weiss, M, Schulz, E.C, Mehrabi, P, Norton-Baker, B, Schmidt, C, Lorenzen, K, Schubert, R, Han, H, Chari, A, Fernandez Garcia, Y, Turk, D, Hilgenfeld, R, Rarey, M, Zaliani, A, Chapman, H.N, Pearson, A, Betzel, C, Meents, A. | 登録日 | 2020-12-12 | 公開日 | 2021-01-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease. Science, 372, 2021
|
|
2BTW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2btw by Molmil](/molmil-images/mine/2btw) | Crystal structure of Alr0975 | 分子名称: | ALR0975 PROTEIN, CALCIUM ION | 著者 | Vivares, D, Arnoux, P, Pignol, D. | 登録日 | 2005-06-07 | 公開日 | 2005-12-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Papain-Like Enzyme at Work: Native and Acyl- Enzyme Intermediate Structures in Phytochelatin Synthesis. Proc.Natl.Acad.Sci.USA, 102, 2005
|
|
2B34
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b34 by Molmil](/molmil-images/mine/2b34) | Structure of MAR1 Ribonuclease from Caenorhabditis elegans | 分子名称: | MAR1 Ribonuclease | 著者 | Schormann, N, Karpova, E, Li, S, Symersky, J, Zhang, Y, Lu, S, Zhou, Q, Lin, G, Cao, Z, Luo, M, Qiu, S, Luan, C.-H, Luo, D, Huang, W, Shang, Q, McKinstry, A, An, J, Tsao, J, Carson, M, Stinnett, M, Chen, Y, Johnson, D, Gary, R, Arabshahi, A, Bunzel, R, Bray, T, DeLucas, L, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2005-09-19 | 公開日 | 2005-09-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.141 Å) | 主引用文献 | Structure of MAR1 Ribonuclease from Caenorhabditis elegans To be Published
|
|
2AK5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ak5 by Molmil](/molmil-images/mine/2ak5) | beta PIX-SH3 complexed with a Cbl-b peptide | 分子名称: | 8-residue peptide from a signal transduction protein CBL-B, Rho guanine nucleotide exchange factor 7 | 著者 | Jozic, D, Cardenes, N, Deribe, Y.L, Moncalian, G, Hoeller, D, Groemping, Y, Dikic, I, Rittinger, K, Bravo, J. | 登録日 | 2005-08-03 | 公開日 | 2005-10-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Cbl promotes clustering of endocytic adaptor proteins. Nat.Struct.Mol.Biol., 12, 2005
|
|
2ATI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ati by Molmil](/molmil-images/mine/2ati) | Glycogen Phosphorylase Inhibitors | 分子名称: | Glycogen phosphorylase, liver form, N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA, ... | 著者 | Klabunde, T, Wendt, K.U, Kadereit, D, Brachvogel, V, Burger, H.J, Herling, A.W, Oikonomakos, N.G, Schmoll, D, Sarubbi, E, von Roedern, E, Schoenafinger, K, Defossa, E. | 登録日 | 2005-08-25 | 公開日 | 2006-08-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. J.Med.Chem., 48, 2005
|
|
2B5B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b5b by Molmil](/molmil-images/mine/2b5b) | A reptilian defensin with anti-bacterial and anti-viral activity | 分子名称: | Defensin | 著者 | Chattopadhyay, S, Sinha, N.K, Banerjee, S, Roy, D, Chattopadhyay, D, Roy, S. | 登録日 | 2005-09-28 | 公開日 | 2006-06-27 | 最終更新日 | 2022-03-09 | 実験手法 | SOLUTION NMR | 主引用文献 | Small cationic protein from a marine turtle has beta-defensin-like fold and antibacterial and antiviral activity. Proteins, 64, 2006
|
|
2C8O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2c8o by Molmil](/molmil-images/mine/2c8o) | lysozyme (1sec) and UV lasr excited fluorescence | 分子名称: | LYSOZYME C | 著者 | Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D. | 登録日 | 2005-12-06 | 公開日 | 2006-03-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops. Acta Crystallogr.,Sect.D, 62, 2006
|
|
2C8R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2c8r by Molmil](/molmil-images/mine/2c8r) | insuline(60sec) and UV laser excited fluorescence | 分子名称: | INSULIN A CHAIN, INSULIN B CHAIN | 著者 | Vernede, X, Lavault, B, Ohana, J, Nurizzo, D, Joly, J, Jacquamet, L, Felisaz, F, Cipriani, F, Bourgeois, D. | 登録日 | 2005-12-06 | 公開日 | 2006-03-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Uv Laser-Excited Fluorescence as a Tool for the Visualization of Protein Crystals Mounted in Loops. Acta Crystallogr.,Sect.D, 62, 2006
|
|
2CJ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cj9 by Molmil](/molmil-images/mine/2cj9) | Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with an analog of seryladenylate | 分子名称: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, CHLORIDE ION, SERYL-TRNA SYNTHETASE, ... | 著者 | Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Soll, D, Weygand-Durasevic, I, Ban, N. | 登録日 | 2006-03-29 | 公開日 | 2006-06-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition Embo J., 25, 2006
|
|
2CIM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cim by Molmil](/molmil-images/mine/2cim) | Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase | 分子名称: | CHLORIDE ION, PLATINUM (II) ION, SERYL-TRNA SYNTHETASE, ... | 著者 | Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Soll, D, Weygand-Durasevic, I, Ban, N. | 登録日 | 2006-03-24 | 公開日 | 2006-06-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition Embo J., 25, 2006
|
|
2CJA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cja by Molmil](/molmil-images/mine/2cja) | Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Soll, D, Weygand-Durasevic, I, Ban, N. | 登録日 | 2006-03-30 | 公開日 | 2006-06-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition Embo J., 25, 2006
|
|
2EJN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ejn by Molmil](/molmil-images/mine/2ejn) | Structural characterization of the tetrameric form of the major cat allergen fel D 1 | 分子名称: | CALCIUM ION, Major allergen I polypeptide chain 1, chain 2 | 著者 | Kaiser, L, Velickovic, T.C, Badia-Martinez, D, Adedoyin, J, Thunberg, S, Hallen, D, Berndt, K, Gronlund, H, Gafvelin, G, van Hage, M, Achour, A. | 登録日 | 2007-03-19 | 公開日 | 2007-04-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Structural characterization of the tetrameric form of the major cat allergen Fel d 1 J.Mol.Biol., 370, 2007
|
|
6Y0Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y0z by Molmil](/molmil-images/mine/6y0z) | X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant Q126K | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | 著者 | Hermann, J, Bischoff, D, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | 登録日 | 2020-02-10 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Controlling Protein Crystallization by Free Energy Guided Design of Interactions at Crystal Contacts Crystals, 11, 2021
|
|
6Y10
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y10 by Molmil](/molmil-images/mine/6y10) | X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant Q126H | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, R-specific alcohol dehydrogenase | 著者 | Hermann, J, Bischoff, D, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | 登録日 | 2020-02-10 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | Controlling Protein Crystallization by Free Energy Guided Design of Interactions at Crystal Contacts Crystals, 11, 2021
|
|
8ILV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ilv by Molmil](/molmil-images/mine/8ilv) | Cryo-EM structure of PI3Kalpha in complex with compound 18 | 分子名称: | N-[(2R)-1-(ethylamino)-1-oxidanylidene-3-[3-(2-quinoxalin-6-ylethynyl)phenyl]propan-2-yl]-2,3-dimethyl-quinoxaline-6-carboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Zhou, Q, Liu, X, Neri, D, Li, W, Favalli, N, Bassi, G, Yang, S, Yang, D, Vogt, P.K, Wang, M.-W. | 登録日 | 2023-03-04 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | Structural insights into the interaction of three Y-shaped ligands with PI3K alpha. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8ILS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ils by Molmil](/molmil-images/mine/8ils) | Cryo-EM structure of PI3Kalpha in complex with compound 17 | 分子名称: | N-[(2R)-1-(ethylamino)-1-oxidanylidene-3-[4-(2-quinoxalin-6-ylethynyl)phenyl]propan-2-yl]-2,3-dimethyl-quinoxaline-6-carboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Zhou, Q, Liu, X, Neri, D, Li, W, Favalli, N, Bassi, G, Yang, S, Yang, D, Vogt, P.K, Wang, M.-W. | 登録日 | 2023-03-04 | 公開日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into the interaction of three Y-shaped ligands with PI3K alpha. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
5K7R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5k7r by Molmil](/molmil-images/mine/5k7r) | MicroED structure of trypsin at 1.7 A resolution | 分子名称: | CALCIUM ION, Cationic trypsin | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2018-08-22 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.7 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
|
|