1OUR
 
 | | LecB (PA-LII) in complex with mannose | | 分子名称: | CALCIUM ION, alpha-D-mannopyranose, hypothetical protein LecB | | 著者 | Loris, R, Tielker, D, Jaeger, K.-E, Wyns, L. | | 登録日 | 2003-03-25 | | 公開日 | 2003-09-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Structural Basis of Carbohydrate Recognition by the Lectin LecB from Pseudomonas aeruginosa
J.MOL.BIOL., 331, 2003
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2WMX
 | | Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors | | 分子名称: | 1-[(2S)-4-(5-phenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)morpholin-2-yl]methanamine, SERINE/THREONINE-PROTEIN KINASE CHK1 | | 著者 | Matthews, T.P, Klair, S, Burns, S, Boxall, K, Cherry, M, Fisher, M, Westwood, I.M, Walton, M.I, McHardy, T, Cheung, K.-M.J, Van Montfort, R, Williams, D, Aherne, G.W, Garrett, M.D, Reader, J, Collins, I. | | 登録日 | 2009-07-03 | | 公開日 | 2009-07-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Identification of Inhibitors of Checkpoint Kinase 1 Through Template Screening.
J.Med.Chem., 52, 2009
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2WMQ
 | | Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors | | 分子名称: | N-(4-OXO-5,6,7,8-TETRAHYDRO-4H-[1,3]THIAZOLO[5,4-C]AZEPIN-2-YL)ACETAMIDE, SERINE/THREONINE-PROTEIN KINASE CHK1 | | 著者 | Matthews, T.P, Klair, S, Burns, S, Boxall, K, Cherry, M, Fisher, M, Westwood, I.M, Walton, M.I, McHardy, T, Cheung, K.-M.J, Van Montfort, R, Williams, D, Aherne, G.W, Garrett, M.D, Reader, J, Collins, I. | | 登録日 | 2009-07-03 | | 公開日 | 2009-07-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Identification of Inhibitors of Checkpoint Kinase 1 Through Template Screening.
J.Med.Chem., 52, 2009
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7OE7
 | | Apo-structure of Lassa virus L protein (well-resolved alpha ribbon) [APO-RIBBON] | | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | | 登録日 | 2021-05-01 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
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7OJK
 | | Lassa virus L protein bound to the distal promoter duplex [DISTAL-PROMOTER] | | 分子名称: | 3' RNA, 5' RNA, RNA-directed RNA polymerase L, ... | | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | | 登録日 | 2021-05-16 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
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2WIW
 | | Crystal structures of Holliday junction resolvases from Archaeoglobus fulgidus bound to DNA substrate | | 分子名称: | 5'-D(*DC*DG*DG*DA*DT*DA*DT*DC*DC*DGP)-3', GLYCEROL, HEXANE-1,6-DIOL, ... | | 著者 | Carolis, C, Koehler, C, Sauter, C, Basquin, J, Suck, D, Toeroe, I. | | 登録日 | 2009-05-18 | | 公開日 | 2009-05-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structures of Holliday Junction Resolvases from Archaeoglobus Fulgidus Bound to DNA Substrate
To be Published
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7OCH
 | | Apo-structure of Lassa virus L protein (well-resolved polymerase core) [APO-CORE] | | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | | 登録日 | 2021-04-26 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
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7OEA
 | | Lassa virus L protein bound to 3' promoter RNA (well-resolved polymerase core) [3END-CORE] | | 分子名称: | 3' vRNA, MAGNESIUM ION, RNA-directed RNA polymerase L, ... | | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | | 登録日 | 2021-05-02 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
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8AF4
 | | Room temperature SSX structure of GH11 xylanase from Nectria haematococca (40000 frames) | | 分子名称: | Endo-1,4-beta-xylanase | | 著者 | Oberthuer, D, Andaleeb, H, Betzel, C, Perbandt, M, Yefanov, O, Zielinski, K. | | 登録日 | 2022-07-15 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive.
Iucrj, 9, 2022
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7OJN
 | | Lassa virus L protein in an elongation conformation [ELONGATION] | | 分子名称: | 3' RNA, 5' RNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... | | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | | 登録日 | 2021-05-16 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
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8AF8
 | | Room temperature SSX crystal structure of CTX-M-14 (5K dataset) | | 分子名称: | Beta-lactamase, SULFATE ION | | 著者 | Oberthuer, D, Perbandt, M, Prester, A, Rohde, H, Betzel, C, Yefanov, O. | | 登録日 | 2022-07-15 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive.
Iucrj, 9, 2022
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2WCZ
 | | 1.6A resolution structure of Archaeoglobus fulgidus Hjc, a Holliday junction resolvase from an archaeal hyperthermophile | | 分子名称: | CHLORIDE ION, HOLLIDAY JUNCTION RESOLVASE | | 著者 | Carolis, C, Koehler, C, Sauter, C, Basquin, J, Suck, D, Toeroe, I. | | 登録日 | 2009-03-18 | | 公開日 | 2009-03-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | 1.6 A Resolution Structure of Archaeoglobus Fulgidus Hjc, a Holliday Junction Resolvase from an Archaeal Hyperthermophile
To be Published
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7OE3
 | | Apo-structure of Lassa virus L protein (well-resolved endonuclease) [APO-ENDO] | | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | | 登録日 | 2021-05-01 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
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8AF5
 | | Room temperature SSX structure of GH11 xylanase from Nectria haematococca (10000 frames) | | 分子名称: | Endo-1,4-beta-xylanase | | 著者 | Oberthuer, D, Andaleeb, H, Betzel, C, Perbandt, M, Yefanov, O, Zielinski, K. | | 登録日 | 2022-07-15 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive.
Iucrj, 9, 2022
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7OJJ
 | | Lassa virus L protein with endonuclease and C-terminal domains in close proximity [MID-LINK] | | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | | 登録日 | 2021-05-16 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
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1P8D
 | | X-Ray Crystal Structure of LXR Ligand Binding Domain with 24(S),25-epoxycholesterol | | 分子名称: | 17-[3-(3,3-DIMETHYL-OXIRANYL)-1-METHYL-PROPYL]-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYC LOPENTA[A]PHENANTHREN-3-OL, Oxysterols receptor LXR-beta, nuclear receptor coactivator 1 isoform 3 | | 著者 | Williams, S, Bledsoe, R.K, Collins, J.L, Boggs, S, Lambert, M.H, Miller, A.B, Moore, J, McKee, D.D, Moore, L, Nichols, J, Parks, D, Watson, M, Wisely, B, Willson, T.M. | | 登録日 | 2003-05-06 | | 公開日 | 2003-07-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by
a histidine-tryptophan switch.
J.Biol.Chem., 278, 2003
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7OEB
 | | Lassa virus L protein bound to 3' promoter RNA (well-resolved endonuclease) [3END-ENDO] | | 分子名称: | 3' vRNA, MAGNESIUM ION, RNA-directed RNA polymerase L, ... | | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | | 登録日 | 2021-05-02 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
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7OJL
 | | Lassa virus L protein in a pre-initiation conformation [PREINITIATION] | | 分子名称: | 3' RNA, 5' RNA, MANGANESE (II) ION, ... | | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | | 登録日 | 2021-05-16 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
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8ADN
 | | Vairimorpha necatrix 20S proteasome from spores | | 分子名称: | Proteasome Inhibitor 31-Like, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... | | 著者 | Jespersen, N, Ehrenbolger, K, Winiger, R, Svedberg, D, Vossbrinck, C.R, Barandun, J. | | 登録日 | 2022-07-08 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Structure of the reduced microsporidian proteasome bound by PI31-like peptides in dormant spores.
Nat Commun, 13, 2022
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2J7E
 | | Beta-glucosidase from Thermotoga maritima in complex with methyl acetate-substituted glucoimidazole | | 分子名称: | ACETATE ION, BETA-GLUCOSIDASE A, CALCIUM ION, ... | | 著者 | Gloster, T.M, Zechel, D, Vasella, A, Davies, G.J. | | 登録日 | 2006-10-07 | | 公開日 | 2006-10-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Glycosidase Inhibition: An Assessment of the Binding of 18 Putative Transition-State Mimics.
J.Am.Chem.Soc., 129, 2007
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2W42
 | | THE STRUCTURE OF A PIWI PROTEIN FROM ARCHAEOGLOBUS FULGIDUS COMPLEXED WITH A 16NT DNA DUPLEX. | | 分子名称: | 5'-D(*GP*TP*CP*GP*AP*AP*TP*TP)-3', 5'-D(*TP*TP*CP*GP*AP*CP*GP*CP)-3', MANGANESE (II) ION, ... | | 著者 | Parker, J.S, Roe, S.M, Barford, D. | | 登録日 | 2008-11-19 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Enhancement of the Seed-Target Recognition Step in RNA Silencing by a Piwi-Mid Domain Protein
Mol.Cell, 33, 2009
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8AS0
 | | PD-1 extracellular domain in complex with Fab fragment from D12 antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ongaro, T, Scietti, L, Pluss, L, Peissert, F, Villa, A, Puca, E, De Luca, R, Neri, D, Forneris, F. | | 登録日 | 2022-08-17 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Selection of a PD-1 blocking antibody from a novel fully human phage display library.
Protein Sci., 31, 2022
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7NTN
 | | The structure of RRM domain of human TRMT2A at 2 A resolution | | 分子名称: | CHLORIDE ION, SODIUM ION, SULFATE ION, ... | | 著者 | Davydova, E, Janowski, R, Witzenberger, M, Niessing, D. | | 登録日 | 2021-03-10 | | 公開日 | 2022-01-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.016 Å) | | 主引用文献 | Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death.
Comput Struct Biotechnol J, 20, 2022
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7OIF
 | | CspA-27 cotranslational folding intermediate 2 | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V. | | 登録日 | 2021-05-11 | | 公開日 | 2022-01-19 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A switch from alpha-helical to beta-strand conformation during co-translational protein folding.
Embo J., 41, 2022
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7OIG
 | | CspA-27 cotranslational folding intermediate 3 | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Agirrezabala, X, Samatova, E, Macher, M, Liutkute, M, Gil-Carton, D, Novacek, J, Valle, M, Rodnina, M.V. | | 登録日 | 2021-05-11 | | 公開日 | 2022-01-19 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | A switch from alpha-helical to beta-strand conformation during co-translational protein folding.
Embo J., 41, 2022
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