2XCG
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![BU of 2xcg by Molmil](/molmil-images/mine/2xcg) | Tranylcypromine-inhibited human monoamine oxidase B in complex with 2- (2-benzofuranyl)-2-imidazoline | Descriptor: | 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, 3-PHENYLPROPANAL, Amine oxidase [flavin-containing] B, ... | Authors: | Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. | Deposit date: | 2010-04-23 | Release date: | 2010-10-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
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2XP7
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![BU of 2xp7 by Molmil](/molmil-images/mine/2xp7) | DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION | Descriptor: | 2-PHENYL-1H-IMIDAZOLE-4,5-DICARBOXYLIC ACID, DODECAETHYLENE GLYCOL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 | Authors: | Potter, A, Oldfield, V, Nunns, C, Fromont, C, Ray, S, Northfield, C.J, Bryant, C.J, Scrace, S.F, Robinson, D, Matossova, N, Baker, L, Dokurno, P, Surgenor, A.E, Davis, B.E, Richardson, C.M, Murray, J.B, Moore, J.D. | Deposit date: | 2010-08-25 | Release date: | 2011-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of Cell-Active Phenyl-Imidazole Pin1 Inhibitors by Structure-Guided Fragment Evolution. Bioorg.Med.Chem.Lett., 20, 2010
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5E5N
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![BU of 5e5n by Molmil](/molmil-images/mine/5e5n) | |
7MBJ
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![BU of 7mbj by Molmil](/molmil-images/mine/7mbj) | |
4O6M
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![BU of 4o6m by Molmil](/molmil-images/mine/4o6m) | Structure of AF2299, a CDP-alcohol phosphotransferase (CMP-bound) | Descriptor: | AF2299, a CDP-alcohol phosphotransferase, CALCIUM ION, ... | Authors: | Clarke, O.B, Sciara, G, Tomasek, D, Banerjee, S, Rajashankar, K.R, Shapiro, L, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2013-12-22 | Release date: | 2014-05-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Structural basis for catalysis in a CDP-alcohol phosphotransferase. Nat Commun, 5, 2014
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1I7B
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![BU of 1i7b by Molmil](/molmil-images/mine/1i7b) | HUMAN S-ADENOSYLMETHIONINE DECARBOXYLASE WITH COVALENTLY BOUND PYRUVOYL GROUP AND COVALENTLY BOUND S-ADENOSYLMETHIONINE METHYL ESTER | Descriptor: | 1,4-DIAMINOBUTANE, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAIN, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAIN, ... | Authors: | Tolbert, W.D, Ekstrom, J.L, Mathews, I.I, Secrist III, J.A, Pegg, A.E, Ealick, S.E. | Deposit date: | 2001-03-08 | Release date: | 2001-08-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase. Biochemistry, 40, 2001
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3U2X
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![BU of 3u2x by Molmil](/molmil-images/mine/3u2x) | Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and 1'-deoxyglucose | Descriptor: | 1,2-ETHANEDIOL, 1,5-anhydro-D-glucitol, Glycogenin-1, ... | Authors: | Chaikuad, A, Froese, D.S, Krysztofinska, E, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Oppermann, U, Yue, W.W, Structural Genomics Consortium (SGC) | Deposit date: | 2011-10-04 | Release date: | 2011-11-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese, UDP and 1'-deoxyglucose To be Published
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1I8T
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![BU of 1i8t by Molmil](/molmil-images/mine/1i8t) | STRUCTURE OF UDP-GALACTOPYRANOSE MUTASE FROM E.COLI | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, UDP-GALACTOPYRANOSE MUTASE | Authors: | Sanders, D.A.R, Staines, A.G, McMahon, S.A, McNeil, M.R, Whitfield, C, Naismith, J.H. | Deposit date: | 2001-03-16 | Release date: | 2001-10-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | UDP-galactopyranose mutase has a novel structure and mechanism. Nat.Struct.Biol., 8, 2001
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1HV5
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![BU of 1hv5 by Molmil](/molmil-images/mine/1hv5) | CRYSTAL STRUCTURE OF THE STROMELYSIN-3 (MMP-11) CATALYTIC DOMAIN COMPLEXED WITH A PHOSPHINIC INHIBITOR | Descriptor: | 1-BENZYLOXYCARBONYLAMINO-2-PHENYL-ETHYL)-{2-[1-CARBAMOYL-2-(1H-INDOL-3-YL)-ETHYLCARBAMOYL]-5-PHENYL-PENTYL}-PHOSPHINIC ACID, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CALCIUM ION, ... | Authors: | Gall, A.L, Ruff, M, Kannan, R, Cuniasse, P, Yiotakis, A, Dive, V, Rio, M.C, Basset, P, Moras, D. | Deposit date: | 2001-01-08 | Release date: | 2001-03-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the stromelysin-3 (MMP-11) catalytic domain complexed with a phosphinic inhibitor mimicking the transition-state. J.Mol.Biol., 307, 2001
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8GK7
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![BU of 8gk7 by Molmil](/molmil-images/mine/8gk7) | MsbA bound to cerastecin C | Descriptor: | 2-[(4-butylbenzene-1-sulfonyl)amino]-5-[(3-{4-[(4-butylbenzene-1-sulfonyl)amino]-3-carboxyanilino}-3-oxopropyl)carbamoyl]benzoic acid, Lipid A export ATP-binding/permease protein MsbA, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Chen, Y, Klein, D. | Deposit date: | 2023-03-17 | Release date: | 2024-04-24 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Cerastecins inhibit membrane lipooligosaccharide transport in drug-resistant Acinetobacter baumannii. Nat Microbiol, 9, 2024
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1HY2
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![BU of 1hy2 by Molmil](/molmil-images/mine/1hy2) | MINIPROTEIN MP-1 COMPLEX WITH STREPTAVIDIN | Descriptor: | MP-1, STREPTAVIDIN | Authors: | Yang, H.W, Liu, D.Q, Fan, X, White, M.A, Fox, R.O. | Deposit date: | 2001-01-17 | Release date: | 2003-06-17 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Conformational Ensemble Analysis of Ligand Binding in Streptavidin Mini-Protein Complexes To be Published
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7MW8
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![BU of 7mw8 by Molmil](/molmil-images/mine/7mw8) | |
1HXL
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![BU of 1hxl by Molmil](/molmil-images/mine/1hxl) | MINIPROTEIN MP-2 (V10A) COMPLEX WITH STREPTAVIDIN | Descriptor: | MP-2, STREPTAVIDIN | Authors: | Yang, H.W, Liu, D.Q, Fan, X, White, M.A, Fox, R.O. | Deposit date: | 2001-01-16 | Release date: | 2003-06-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Conformational Ensemble Analysis of Ligand Binding in Streptavidin Mini-Protein Complexes To be Published
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1HXZ
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![BU of 1hxz by Molmil](/molmil-images/mine/1hxz) | MINIPROTEIN MP-2 COMPLEX WITH STREPTAVIDIN | Descriptor: | MP-2, STREPTAVIDIN | Authors: | Yang, H.W, Liu, D.Q, Fan, X, White, M.A, Fox, R.O. | Deposit date: | 2001-01-17 | Release date: | 2003-06-17 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Conformational Ensemble Analysis of Ligand Binding in Streptavidin Mini-Protein Complexes To be Published
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1I4W
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![BU of 1i4w by Molmil](/molmil-images/mine/1i4w) | THE CRYSTAL STRUCTURE OF THE TRANSCRIPTION FACTOR SC-MTTFB OFFERS INTRIGUING INSIGHTS INTO MITOCHONDRIAL TRANSCRIPTION | Descriptor: | MITOCHONDRIAL REPLICATION PROTEIN MTF1, XENON | Authors: | Schubot, F.D, Chen, C.-J, Rose, J.P, Dailey, T.A, Dailey, H.A, Wang, B.-C. | Deposit date: | 2001-02-23 | Release date: | 2001-10-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the transcription factor sc-mtTFB offers insights into mitochondrial transcription. Protein Sci., 10, 2001
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7MVW
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![BU of 7mvw by Molmil](/molmil-images/mine/7mvw) | Crystal structure of Chaetomium thermophilum Nup188 NTD (residues 1-1134) | Descriptor: | GLYCEROL, Nucleoporin NUP188 | Authors: | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | Deposit date: | 2021-05-15 | Release date: | 2022-06-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Architecture of the linker-scaffold in the nuclear pore. Science, 376, 2022
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6WC6
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![BU of 6wc6 by Molmil](/molmil-images/mine/6wc6) | |
7MVV
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![BU of 7mvv by Molmil](/molmil-images/mine/7mvv) | Single particle cryo-EM structure of the Chaetomium thermophilum Nup192-Nic96-Nup53-Nup145N complex (Nup192 residues 1-1756; Nic96 residues 240-301; Nup53 31-67; Nup145N 616-683) | Descriptor: | Nucleoporin NIC96, Nucleoporin NUP145N, Nucleoporin NUP192, ... | Authors: | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | Deposit date: | 2021-05-15 | Release date: | 2022-06-15 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Architecture of the linker-scaffold in the nuclear pore. Science, 376, 2022
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3UAR
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![BU of 3uar by Molmil](/molmil-images/mine/3uar) | Crystal structure of glutathione transferase (TARGET EFI-501774) from methylococcus capsulatus str. bath with gsh bound | Descriptor: | GLUTATHIONE, GLYCEROL, Glutathione S-transferase | Authors: | Patskovsky, Y, Toro, R, Bhosle, R, Zencheck, W.D, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2011-10-21 | Release date: | 2011-11-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of Glutathione S-Transferase from Methylococcus Capsulatus To be Published
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5KWO
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![BU of 5kwo by Molmil](/molmil-images/mine/5kwo) | |
5KY6
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![BU of 5ky6 by Molmil](/molmil-images/mine/5ky6) | |
6R2O
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![BU of 6r2o by Molmil](/molmil-images/mine/6r2o) | Hemoglobin structure from serial crystallography with a 3D-printed nozzle. | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Hemoglobin subunit alpha, ... | Authors: | Oberthuer, D, Yefanov, O, Sarrou, I. | Deposit date: | 2019-03-18 | Release date: | 2020-01-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Ultracompact 3D microfluidics for time-resolved structural biology. Nat Commun, 11, 2020
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3UBL
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![BU of 3ubl by Molmil](/molmil-images/mine/3ubl) | Crystal structure of glutathione transferase (TARGET EFI-501770) from leptospira interrogans with gsh bound | Descriptor: | CHLORIDE ION, GLUTATHIONE, GLYCEROL, ... | Authors: | Patskovsky, Y, Toro, R, Bhosle, R, Zencheck, W.D, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2011-10-24 | Release date: | 2011-11-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Glutathione S-Transferase from Leptospira Interrogans To be Published
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8GJR
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![BU of 8gjr by Molmil](/molmil-images/mine/8gjr) | |
2XNZ
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![BU of 2xnz by Molmil](/molmil-images/mine/2xnz) | xpt-pbuX C74U Riboswitch from B. subtilis bound to acetoguanamine identified by virtual screening | Descriptor: | 6-METHYL-1,3,5-TRIAZINE-2,4-DIAMINE, ACETATE ION, COBALT HEXAMMINE(III), ... | Authors: | Daldrop, P, Reyes, F.E, Robinson, D.A, Hammond, C.M, Lilley, D.M.J, Batey, R.T, Brenk, R. | Deposit date: | 2010-08-06 | Release date: | 2011-04-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Novel ligands for a purine riboswitch discovered by RNA-ligand docking. Chem. Biol., 18, 2011
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